Luis F. Santana Department of Physiology & Biophysics University of Washington Biography Publications Institution JoVE Articles Luis F. Santana has not added a biography. If you are Luis F. Santana and would like to personalize this page please email our Author Liaison for assistance. Publications Ca2+ Signaling Amplification by Oligomerization of L-type Cav1.2 Channels Proceedings of the National Academy of Sciences of the United States of America. Jan, 2012 | Pubmed ID: 22307641 Dynamic Changes in Sarcoplasmic Reticulum Structure in Ventricular Myocytes Journal of Biomedicine & Biotechnology. 2011 | Pubmed ID: 22131804 An Entirely Specific Type I A-kinase Anchoring Protein That Can Sequester Two Molecules of Protein Kinase A at Mitochondria Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 22084075 Relationship Between Ca2+ Sparklets and Sarcoplasmic Reticulum Ca2+ Load and Release in Rat Cerebral Arterial Smooth Muscle American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2011 | Pubmed ID: 21984539 Restoration of Normal L-type Ca2+ Channel Function During Timothy Syndrome by Ablation of an Anchoring Protein Circulation Research. Jul, 2011 | Pubmed ID: 21700933 Mitochondrial Targeted Antioxidant Peptide Ameliorates Hypertensive Cardiomyopathy Journal of the American College of Cardiology. Jun, 2011 | Pubmed ID: 21620606 Mitochondrial Oxidative Stress Mediates Angiotensin II-induced Cardiac Hypertrophy and Galphaq Overexpression-induced Heart Failure Circulation Research. Apr, 2011 | Pubmed ID: 21311045 Eosinophil Cysteinyl Leukotriene Synthesis Mediated by Exogenous Secreted Phospholipase A2 Group X The Journal of Biological Chemistry. Dec, 2010 | Pubmed ID: 20974857 How Does the Shape of the Cardiac Action Potential Control Calcium Signaling and Contraction in the Heart? Journal of Molecular and Cellular Cardiology. Dec, 2010 | Pubmed ID: 20850450 Sympathetic Stimulation of Adult Cardiomyocytes Requires Association of AKAP5 with a Subpopulation of L-type Calcium Channels Circulation Research. Sep, 2010 | Pubmed ID: 20671242 Natural Inequalities: Why Some L-type Ca2+ Channels Work Harder Than Others The Journal of General Physiology. Aug, 2010 | Pubmed ID: 20660657 Phosphodiesterase 8A (PDE8A) Regulates Excitation-contraction Coupling in Ventricular Myocytes Journal of Molecular and Cellular Cardiology. Aug, 2010 | Pubmed ID: 20353794 A-kinase Anchoring Proteins: Getting to the Heart of the Matter Circulation. Mar, 2010 | Pubmed ID: 20231544 Knockout of Na+/Ca2+ Exchanger in Smooth Muscle Attenuates Vasoconstriction and L-type Ca2+ Channel Current and Lowers Blood Pressure American Journal of Physiology. Heart and Circulatory Physiology. May, 2010 | Pubmed ID: 20173044 Increased Coupled Gating of L-type Ca2+ Channels During Hypertension and Timothy Syndrome Circulation Research. Mar, 2010 | Pubmed ID: 20110531 Elevated Ca2+ Sparklet Activity During Acute Hyperglycemia and Diabetes in Cerebral Arterial Smooth Muscle Cells American Journal of Physiology. Cell Physiology. Feb, 2010 | Pubmed ID: 19846755 Myostatin Represses Physiological Hypertrophy of the Heart and Excitation-contraction Coupling The Journal of Physiology. Oct, 2009 | Pubmed ID: 19736304 Molecular and Biophysical Mechanisms of Ca2+ Sparklets in Smooth Muscle Journal of Molecular and Cellular Cardiology. Oct, 2009 | Pubmed ID: 19616004 Overexpression of Catalase Targeted to Mitochondria Attenuates Murine Cardiac Aging Circulation. Jun, 2009 | Pubmed ID: 19451351 Local Control of Excitation-contraction Coupling in Human Embryonic Stem Cell-derived Cardiomyocytes PloS One. 2009 | Pubmed ID: 19404384 NFATc3-dependent Loss of I(to) Gradient Across the Left Ventricular Wall During Chronic Beta Adrenergic Stimulation Journal of Molecular and Cellular Cardiology. Feb, 2009 | Pubmed ID: 19027024 The Control of Ca2+ Influx and NFATc3 Signaling in Arterial Smooth Muscle During Hypertension Proceedings of the National Academy of Sciences of the United States of America. Oct, 2008 | Pubmed ID: 18832165 NFAT-dependent Excitation-transcription Coupling in Heart Circulation Research. Sep, 2008 | Pubmed ID: 18818410 Calcium Sparklets in Arterial Smooth Muscle Clinical and Experimental Pharmacology & Physiology. Sep, 2008 | Pubmed ID: 18215181 AKAP150 is Required for Stuttering Persistent Ca2+ Sparklets and Angiotensin II-induced Hypertension Circulation Research. Feb, 2008 | Pubmed ID: 18174462 SMAKing Ca2+ Sparks in Arterial Myocytes The Journal of Physiology. Oct, 2007 | Pubmed ID: 17717006 Ca(v)1.3 Channels Produce Persistent Calcium Sparklets, but Ca(v)1.2 Channels Are Responsible for Sparklets in Mouse Arterial Smooth Muscle American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2007 | Pubmed ID: 17526649 Calcium Sparklets Regulate Local and Global Calcium in Murine Arterial Smooth Muscle The Journal of Physiology. Feb, 2007 | Pubmed ID: 17158168 Activation of NFATc3 Down-regulates the Beta1 Subunit of Large Conductance, Calcium-activated K+ Channels in Arterial Smooth Muscle and Contributes to Hypertension The Journal of Biological Chemistry. Feb, 2007 | Pubmed ID: 17148444 Phosphoinositide 3-kinase Binds to TRPV1 and Mediates NGF-stimulated TRPV1 Trafficking to the Plasma Membrane The Journal of General Physiology. Nov, 2006 | Pubmed ID: 17074976 Mechanisms Underlying Heterogeneous Ca2+ Sparklet Activity in Arterial Smooth Muscle The Journal of General Physiology. Jun, 2006 | Pubmed ID: 16702354 Differential Calcineurin/NFATc3 Activity Contributes to the Ito Transmural Gradient in the Mouse Heart Circulation Research. May, 2006 | Pubmed ID: 16614306 Kv2 Channels Oppose Myogenic Constriction of Rat Cerebral Arteries American Journal of Physiology. Cell Physiology. Aug, 2006 | Pubmed ID: 16571867 On the Loose: Uncaging Ca2+ -induced Ca2+ Release in Smooth Muscle The Journal of General Physiology. Mar, 2006 | Pubmed ID: 16505144 Mechanisms Underlying Variations in Excitation-contraction Coupling Across the Mouse Left Ventricular Free Wall The Journal of Physiology. Apr, 2006 | Pubmed ID: 16423856 Sodium Current and Arrhythmogenesis in Heart Failure Heart Failure Clinics. Jul, 2005 | Pubmed ID: 17386846 Constitutively Active L-type Ca2+ Channels Proceedings of the National Academy of Sciences of the United States of America. Aug, 2005 | Pubmed ID: 16040810 Alterations in Early Action Potential Repolarization Causes Localized Failure of Sarcoplasmic Reticulum Ca2+ Release Circulation Research. Mar, 2005 | Pubmed ID: 15705962 NFATc3 Regulates Kv2.1 Expression in Arterial Smooth Muscle The Journal of Biological Chemistry. Nov, 2004 | Pubmed ID: 15322114 Modulation of the Molecular Composition of Large Conductance, Ca(2+) Activated K(+) Channels in Vascular Smooth Muscle During Hypertension The Journal of Clinical Investigation. Sep, 2003 | Pubmed ID: 12952920 Single Cell транскрипции Профилирование взрослых кардиомиоцитов мышь James M. Flynn1, Luis F. Santana2, Simon Melov1 1Buck Institute for Research on Aging, 2Department of Physiology & Biophysics, University of Washington JoVE 3302 Biology
Single Cell транскрипции Профилирование взрослых кардиомиоцитов мышь James M. Flynn1, Luis F. Santana2, Simon Melov1 1Buck Institute for Research on Aging, 2Department of Physiology & Biophysics, University of Washington JoVE 3302 Biology