Magnus Stougaard Department of Clinical Medicine Aarhus University Biography Publications Institution JoVE Articles Magnus Stougaard has not added a biography. If you are Magnus Stougaard and would like to personalize this page please email our Author Liaison for assistance. Publications Prognostic Value of Mutations, Mutations and PD-L1 Expression Among Lung Adenocarcinomas Treated with Immunotherapy Journal of Clinical Pathology. Nov, 2022 | Pubmed ID: 36410939 Rolling Circle Enhanced Detection of Specific Restriction Endonuclease Activities in Crude Cell Extracts Sensors (Basel, Switzerland). Oct, 2022 | Pubmed ID: 36298113 Impact of New Molecular Criteria on Diagnosis and Survival of Adult Glioma Patients IBRO Neuroscience Reports. Dec, 2022 | Pubmed ID: 36204252 The Psychiatric Risk Gene BRD1 Modulates Mitochondrial Bioenergetics by Transcriptional Regulation Translational Psychiatry. Aug, 2022 | Pubmed ID: 35941107 The Diagnostic Value of Circulating Cell-Free HPV DNA in Plasma from Cervical Cancer Patients Cells. Jul, 2022 | Pubmed ID: 35883612 Topoisomerase 1 Inhibits MYC Promoter Activity by Inducing G-quadruplex Formation Nucleic Acids Research. Jun, 2022 | Pubmed ID: 35687110 Targeted Next Generation Sequencing for Human Papillomavirus Genotyping in Cervical Liquid-Based Cytology Samples Cancers. Jan, 2022 | Pubmed ID: 35158920 A Targeted Expression Panel for Classification, Gene Fusion Detection and PD-L1 Measurements - Can Molecular Profiling Replace Immunohistochemistry in Non-small Cell Lung Cancer? Experimental and Molecular Pathology. Apr, 2022 | Pubmed ID: 35093316 TDP1 and TOP1 As Targets in Anticancer Treatment of NSCLC: Activity and Protein Level in Normal and Tumor Tissue from 150 NSCLC Patients Correlated to Clinical Data Lung Cancer (Amsterdam, Netherlands). Feb, 2022 | Pubmed ID: 34974222 Simple and Fast DNA Based Sensor System for Screening of Small-Molecule Compounds Targeting Eukaryotic Topoisomerase 1 Pharmaceutics. Aug, 2021 | Pubmed ID: 34452216 A Dual-Sensor-Based Screening System for In Vitro Selection of TDP1 Inhibitors Sensors (Basel, Switzerland). Jul, 2021 | Pubmed ID: 34300575 Frequently Used Quantitative Polymerase Chain Reaction-based Methods Overlook Potential Clinically Relevant Genetic Alterations in Epidermal Growth Factor Receptor Compared with Next-generation Sequencing: a Retrospective Clinical Comparison of 1839 Lung Adenocarcinomas Human Pathology. Sep, 2021 | Pubmed ID: 34153308 SNP-based Detection of Allelic Imbalance: A Novel Approach for Identifying KIAA1549-BRAF Fusion in Pilocytic Astrocytoma Using DNA Sequencing Experimental and Molecular Pathology. Jun, 2021 | Pubmed ID: 33626378 Targeted Next Generation Sequencing Panel for HPV Genotyping in Cervical Cancer Experimental and Molecular Pathology. Feb, 2021 | Pubmed ID: 33171155 Different Camptothecin Sensitivities in Subpopulations of Colon Cancer Cells Correlate with Expression of Different Phospho-Isoforms of Topoisomerase I with Different Activities Cancers. May, 2020 | Pubmed ID: 32423158 FcRn Overexpression in Human Cancer Drives Albumin Recycling and Cell Growth; a Mechanistic Basis for Exploitation in Targeted Albumin-drug Designs Journal of Controlled Release : Official Journal of the Controlled Release Society. Jun, 2020 | Pubmed ID: 32145268 Detection of MRNA of Telomerase Protein in Benign Naevi and Melanomas Using RNAscope Applied Immunohistochemistry & Molecular Morphology : AIMM. Jan, 2020 | Pubmed ID: 30095463 Topoisomerase I Activity and Sensitivity to Camptothecin in Breast Cancer-derived Cells: a Comparative Study BMC Cancer. Nov, 2019 | Pubmed ID: 31783818 Enzymatic Activity in Single Cells Methods in Enzymology. 2019 | Pubmed ID: 31668235 Characterization and Radiosensitivity of HPV-related Oropharyngeal Squamous Cell Carcinoma Patient-derived Xenografts Acta Oncologica (Stockholm, Sweden). Oct, 2019 | Pubmed ID: 31510843 Intra-individual Variation of Circulating Tumour DNA in Lung Cancer Patients Molecular Oncology. Oct, 2019 | Pubmed ID: 31306545 Distinguishing Recurrence and New Primary Tumor As Well As the Origin of Neck Metastases in Head and Neck Cancer Clinical Trials by Targeted DNA Sequencing Acta Oncologica (Stockholm, Sweden). Oct, 2019 | Pubmed ID: 31271080 Rapid and Efficient Gene Deletion by CRISPR/Cas9 Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 30912049 A New DNA Sensor System for Specific and Quantitative Detection of Mycobacteria Nanoscale. Jan, 2019 | Pubmed ID: 30556557 Telomerase Reverse Transcriptase Promoter Mutations and Solar Elastosis in Cutaneous Melanoma Melanoma Research. Oct, 2018 | Pubmed ID: 29570169 Detection of the Malaria Causing Plasmodium Parasite in Saliva from Infected Patients Using Topoisomerase I Activity As a Biomarker Scientific Reports. Mar, 2018 | Pubmed ID: 29515150 Characterization of Camptothecin-induced Genomic Changes in the Camptothecin-resistant T-ALL-derived Cell Line CPT-K5 Cancer Genomics & Proteomics. 2018 | Pubmed ID: 29496689 On-slide Detection of Enzymatic Activities in Selected Single Cells Nanoscale. Sep, 2017 | Pubmed ID: 28872165 Quantification of MicroRNA-21 and MicroRNA-125b in Melanoma Tissue Melanoma Research. Oct, 2017 | Pubmed ID: 28614272 Interlinked DNA Nano-circles for Measuring Topoisomerase II Activity at the Level of Single Decatenation Events Nucleic Acids Research. Jul, 2017 | Pubmed ID: 28541438 The Effects of Dithiothreitol on DNA Sensors (Basel, Switzerland). May, 2017 | Pubmed ID: 28538659 Advantages of an Optical Nanosensor System for the Mechanistic Analysis of a Novel Topoisomerase I Targeting Drug: a Case Study Nanoscale. Feb, 2017 | Pubmed ID: 28094391 Novel DNA Sensor System for Highly Sensitive and Quantitative Retrovirus Detection Using Virus Encoded Integrase As a Biomarker Nanoscale. Jan, 2017 | Pubmed ID: 27934981 Optimized Detection of Plasmodium Falciparum Topoisomerase I Enzyme Activity in a Complex Biological Sample by the Use of Molecular Beacons Sensors (Basel, Switzerland). Nov, 2016 | Pubmed ID: 27854277 Molecular Characterization of Irinotecan (SN-38) Resistant Human Breast Cancer Cell Lines BMC Cancer. Jan, 2016 | Pubmed ID: 26801902 Generation of a Double Transgenic Humanized Neonatal Fc Receptor (FcRn)/albumin Mouse to Study the Pharmacokinetics of Albumin-linked Drugs Journal of Controlled Release : Official Journal of the Controlled Release Society. Feb, 2016 | Pubmed ID: 26699424 Microfluidics-Enabled Enzyme Activity Measurement in Single Cells Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 26542724 Correlation Between Topoisomerase I and Tyrosyl-DNA Phosphodiesterase 1 Activities in Non-small Cell Lung Cancer Tissue Experimental and Molecular Pathology. Aug, 2015 | Pubmed ID: 25987486 Real-time Investigation of Human Topoisomerase I Reaction Kinetics Using an Optical Sensor: a Fast Method for Drug Screening and Determination of Active Enzyme Concentrations Nanoscale. Jun, 2015 | Pubmed ID: 25963854 The Parental Origin Correlates with the Karyotype of Human Embryos Developing from Tripronuclear Zygotes Clinical and Experimental Reproductive Medicine. Mar, 2015 | Pubmed ID: 25874169 In-situ Hybridization-based Quantification of HTR: a Possible Biomarker in Malignant Melanoma Histopathology. Apr, 2015 | Pubmed ID: 25601620 Decreased Camptothecin Sensitivity of the Stem-cell-like Fraction of Caco2 Cells Correlates with an Altered Phosphorylation Pattern of Topoisomerase I PloS One. 2014 | Pubmed ID: 24960044 Topoisomerase I As a Biomarker: Detection of Activity at the Single Molecule Level Sensors (Basel, Switzerland). Jan, 2014 | Pubmed ID: 24434877 DNA-based Nanosensors for Next-generation Clinical Diagnostics Via Detection of Enzyme Activity Expert Review of Molecular Diagnostics. Jan, 2014 | Pubmed ID: 24308335 Real-time Detection of TDP1 Activity Using a Fluorophore-quencher Coupled DNA-biosensor Biosensors & Bioelectronics. Oct, 2013 | Pubmed ID: 23693093 DNA-based Sensor for Real-time Measurement of the Enzymatic Activity of Human Topoisomerase I Sensors (Basel, Switzerland). Mar, 2013 | Pubmed ID: 23529147 Droplet Microfluidics Platform for Highly Sensitive and Quantitative Detection of Malaria-causing Plasmodium Parasites Based on Enzyme Activity Measurement ACS Nano. Dec, 2012 | Pubmed ID: 23121492 Microfluidics-mediated Isothermal Detection of Enzyme Activity at the Single Molecule Level Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. Aug, 2011 | Pubmed ID: 22255034 Detection of Single Enzymatic Events in Rare or Single Cells Using Microfluidics ACS Nano. Oct, 2011 | Pubmed ID: 21936557 Strategies for Highly Sensitive Biomarker Detection by Rolling Circle Amplification of Signals from Nucleic Acid Composed Sensors Integrative Biology : Quantitative Biosciences from Nano to Macro. Oct, 2011 | Pubmed ID: 21927767 Multiplexed Detection of Site Specific Recombinase and DNA Topoisomerase Activities at the Single Molecule Level ACS Nano. Dec, 2009 | Pubmed ID: 19950974 Single-molecule Detection of Human Topoisomerase I Cleavage-ligation Activity ACS Nano. Jan, 2009 | Pubmed ID: 19206270 Detection of Short Repeated Genomic Sequences on Metaphase Chromosomes Using Padlock Probes and Target Primed Rolling Circle DNA Synthesis BMC Molecular Biology. Nov, 2007 | Pubmed ID: 17997865 In Situ Detection of Non-polyadenylated RNA Molecules Using Turtle Probes and Target Primed Rolling Circle PRINS BMC Biotechnology. Oct, 2007 | Pubmed ID: 17945012 A New Enzymatic Route for Production of Long 5'-phosphorylated Oligonucleotides Using Suicide Cassettes and Rolling Circle DNA Synthesis BMC Biotechnology. Aug, 2007 | Pubmed ID: 17705815 Eenvoudige en snelle detectie van topoisomerase 1-activiteit in ruwe biologische monsters op basis van versterking van de rollende cirkel Josephine Geertsen Keller1,2, Karol Mizielinski3, Kamilla Vandsø Petersen1,2, Magnus Stougaard2,3,4, Birgitta R. Knudsen1,3, Cinzia Tesauro3 1Department of Molecular Biology and Genetics, Aarhus University, 2Department of Clinical Medicine, Aarhus University, 3VPCIR Biosciences ApS, 4Department of Pathology, Aarhus University Hospital JoVE 64484 Cancer Research
Eenvoudige en snelle detectie van topoisomerase 1-activiteit in ruwe biologische monsters op basis van versterking van de rollende cirkel Josephine Geertsen Keller1,2, Karol Mizielinski3, Kamilla Vandsø Petersen1,2, Magnus Stougaard2,3,4, Birgitta R. Knudsen1,3, Cinzia Tesauro3 1Department of Molecular Biology and Genetics, Aarhus University, 2Department of Clinical Medicine, Aarhus University, 3VPCIR Biosciences ApS, 4Department of Pathology, Aarhus University Hospital JoVE 64484 Cancer Research
