Malin Parmar

Publications

• Towards Stem Cell Based Therapies for Parkinson's Disease
  Development (Cambridge, England). Jan, 2018  |   Pubmed ID: 29311261
• Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus
  Stem Cells International. 2017  |   Pubmed ID: 29317869
• Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming
  Cell Stem Cell. Dec, 2017  |   Pubmed ID: 29174331
• Human Trials of Stem Cell-Derived Dopamine Neurons for Parkinson's Disease: Dawn of a New Era
  Cell Stem Cell. Nov, 2017  |   Pubmed ID: 29100010
• Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned?
  Frontiers in Neuroscience. 2017  |   Pubmed ID: 29033781
• IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells
  Stem Cell Reports. Oct, 2017  |   Pubmed ID: 28943253
• Human IPS Cell-derived Dopaminergic Neurons Function in a Primate Parkinson's Disease Model
  Nature. 08, 2017  |   Pubmed ID: 28858313
• Generation of High-purity Human Ventral Midbrain Dopaminergic Progenitors for in Vitro Maturation and Intracerebral Transplantation
  Nature Protocols. Sep, 2017  |   Pubmed ID: 28858290
• Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons
  Stem Cell Reports. Sep, 2017  |   Pubmed ID: 28844658
• Term Amniotic Fluid: an Unexploited Reserve of Mesenchymal Stromal Cells for Reprogramming and Potential Cell Therapy Applications
  Stem Cell Research & Therapy. Aug, 2017  |   Pubmed ID: 28841906
• REST Suppression Mediates Neural Conversion of Adult Human Fibroblasts Via MicroRNA-dependent and -independent Pathways
  EMBO Molecular Medicine. Aug, 2017  |   Pubmed ID: 28646119
• Strategies for Bringing Stem Cell-derived Dopamine Neurons to the Clinic: A European Approach (STEM-PD)
  Progress in Brain Research. 2017  |   Pubmed ID: 28552228
• Synaptic Inputs from Stroke-injured Brain to Grafted Human Stem Cell-derived Neurons Activated by Sensory Stimuli
  Brain : a Journal of Neurology. Mar, 2017  |   Pubmed ID: 28115364
• Single-Cell Analysis Reveals a Close Relationship Between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages
  Cell Stem Cell. Jan, 2017  |   Pubmed ID: 28094018
• Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of HESC-Based Therapy for Parkinson's Disease
  Cell Stem Cell. Jan, 2017  |   Pubmed ID: 28094017
• TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells
  Cell Reports. Jan, 2017  |   Pubmed ID: 28052240
• Small Molecules Increase Direct Neural Conversion of Human Fibroblasts
  Scientific Reports. Dec, 2016  |   Pubmed ID: 27917895
• Plug and Play Brain: Understanding Integration of Transplanted Neurons for Brain Repair
  Cell Stem Cell. 12, 2016  |   Pubmed ID: 27912087
• Comparability: Manufacturing, Characterization and Controls, Report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015
  Regenerative Medicine. Jul, 2016  |   Pubmed ID: 27404768
• HESC-derived Neural Progenitors Prevent Xenograft Rejection Through Neonatal Desensitisation
  Experimental Neurology. Aug, 2016  |   Pubmed ID: 27235932
• DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor
  Neuron. Jun, 2016  |   Pubmed ID: 27161524
• Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?
  Journal of Parkinson's Disease. 2016  |   Pubmed ID: 27003785
• In Vivo Reprogramming for Brain and Spinal Cord Repair
  ENeuro. Sep-Oct, 2015  |   Pubmed ID: 26730402
• Comprehensive Analysis of MicroRNA Expression in Regionalized Human Neural Progenitor Cells Reveals MicroRNA-10 As a Caudalizing Factor
  Development (Cambridge, England). Sep, 2015  |   Pubmed ID: 26395143
• Cell-based Therapies for Parkinson Disease—past Insights and Future Potential
  Nature Reviews. Neurology. Sep, 2015  |   Pubmed ID: 26240036
• In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons That Integrate into Local Host Circuitry
  Cell Reports. Jul, 2015  |   Pubmed ID: 26166567
• Monosynaptic Tracing Using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons
  Stem Cell Reports. Jun, 2015  |   Pubmed ID: 26004633
• Human ESC-derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson's Disease
  Cell Stem Cell. Nov, 2014  |   Pubmed ID: 25517469
• Direct Neural Conversion from Human Fibroblasts Using Self-regulating and Nonintegrating Viral Vectors
  Cell Reports. Dec, 2014  |   Pubmed ID: 25482564
• Highly Efficient Generation of Induced Neurons from Human Fibroblasts That Survive Transplantation into the Adult Rat Brain
  Scientific Reports. Sep, 2014  |   Pubmed ID: 25208484
• Isolation of Human Induced Pluripotent Stem Cell-derived Dopaminergic Progenitors by Cell Sorting for Successful Transplantation
  Stem Cell Reports. Mar, 2014  |   Pubmed ID: 24672756
• The Novel MAPT Mutation K298E: Mechanisms of Mutant Tau Toxicity, Brain Pathology and Tau Expression in Induced Fibroblast-derived Neurons
  Acta Neuropathologica. Feb, 2014  |   Pubmed ID: 24292008
• Human Foetal Brain Tissue As Quality Control when Developing Stem Cells Towards Cell Replacement Therapy for Neurological Diseases
  Neuroreport. Dec, 2013  |   Pubmed ID: 24257249
• Generation of Induced Neurons Via Direct Conversion in Vivo
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013  |   Pubmed ID: 23530235
• Efficient Expansion and Dopaminergic Differentiation of Human Fetal Ventral Midbrain Neural Stem Cells by Midbrain Morphogens
  Neurobiology of Disease. Jan, 2013  |   Pubmed ID: 22940632
• Generating Regionalized Neuronal Cells from Pluripotency, a Step-by-step Protocol
  Frontiers in Cellular Neuroscience. 2012  |   Pubmed ID: 23316134
• Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells Under Defined Conditions
  Cell Reports. Jun, 2012  |   Pubmed ID: 22813745
• Identification of Embryonic Stem Cell-derived Midbrain Dopaminergic Neurons for Engraftment
  The Journal of Clinical Investigation. Aug, 2012  |   Pubmed ID: 22751106
• Generation of Transplantable Striatal Projection Neurons from Human ESCs
  Cell Stem Cell. Apr, 2012  |   Pubmed ID: 22482498
• Efficient Induction of Functional Neurons from Adult Human Fibroblasts
  Cell Cycle (Georgetown, Tex.). Oct, 2011  |   Pubmed ID: 21934358
• Turning Skin into Dopamine Neurons
  Cell Research. Oct, 2011  |   Pubmed ID: 21826107
• Direct Conversion of Human Fibroblasts to Dopaminergic Neurons
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2011  |   Pubmed ID: 21646515
• Neural Grafting in Parkinson's Disease Problems and Possibilities
  Progress in Brain Research. 2010  |   Pubmed ID: 20887880
• Tracking Differentiating Neural Progenitors in Pluripotent Cultures Using MicroRNA-regulated Lentiviral Vectors
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010  |   Pubmed ID: 20534548
• Organization of the Human Embryonic Ventral Mesencephalon
  Gene Expression Patterns : GEP. Dec, 2009  |   Pubmed ID: 19825428
• Dopamine Neuron Precursors Within the Developing Human Mesencephalon Show Radial Glial Characteristics
  Glia. Nov, 2009  |   Pubmed ID: 19330857
• Reprogramming of Neonatal SVZ Progenitors by Islet-1 and Neurogenin-2
  Molecular and Cellular Neurosciences. Jul, 2008  |   Pubmed ID: 18524626
• Early Specification of Dopaminergic Phenotype During ES Cell Differentiation
  BMC Developmental Biology. Jul, 2007  |   Pubmed ID: 17640353
• Ngn2 and Nurr1 Act in Synergy to Induce Midbrain Dopaminergic Neurons from Expanded Neural Stem and Progenitor Cells
  Experimental Cell Research. Apr, 2007  |   Pubmed ID: 17291494
• In Vitro Characterization of a Human Neural Progenitor Cell Coexpressing SSEA4 and CD133
  Journal of Neuroscience Research. Feb, 2007  |   Pubmed ID: 17131412
• Strengths and Limitations of the Neurosphere Culture System
  Molecular Neurobiology. Dec, 2006  |   Pubmed ID: 17308349
• Retrovirally Delivered Islet-1 Increases Recruitment of Ng2 Expressing Cells from the Postnatal SVZ into the Striatum
  Experimental Neurology. Oct, 2006  |   Pubmed ID: 16806175
• Neurogenin2 Identifies a Transplantable Dopamine Neuron Precursor in the Developing Ventral Mesencephalon
  Experimental Neurology. Mar, 2006  |   Pubmed ID: 16438966
• Striatal Neuron Differentiation from Neurosphere-expanded Progenitors Depends on Gsh2 Expression
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2004  |   Pubmed ID: 15295031
• Phenotypic and Molecular Identity of Cells in the Adult Subventricular Zone. in Vivo and After Expansion in Vitro
  Molecular and Cellular Neurosciences. Nov, 2003  |   Pubmed ID: 14664822
• A Transplantation Study of Expanded Human Embryonic Forebrain Precursors: Evidence for Selection of a Specific Progenitor Population
  Molecular and Cellular Neurosciences. Aug, 2003  |   Pubmed ID: 12932435
• Regional Specification of Neurosphere Cultures Derived from Subregions of the Embryonic Telencephalon
  Molecular and Cellular Neurosciences. Dec, 2002  |   Pubmed ID: 12504597