Marc Freichel Pharmakologisches Institut Ruprecht-Karls-Universität Heidelberg Biography Publications Institution JoVE Articles Marc Freichel has not added a biography. If you are Marc Freichel and would like to personalize this page please email our Author Liaison for assistance. Publications Development of an AAV9-RNAi-mediated Silencing Strategy to Abrogate TRPM4 Expression in the Adult Heart Pflugers Archiv : European Journal of Physiology. Mar, 2021 | Pubmed ID: 33580817 Transcriptional Signatures Regulated by TRPC1/C4-mediated Background Ca Entry After Pressure-overload Induced Cardiac Remodelling Progress in Biophysics and Molecular Biology. 01, 2021 | Pubmed ID: 32738354 Genetic Background Influences Expression and Function of the Cation Channel TRPM4 in the Mouse Heart Basic Research in Cardiology. 11, 2020 | Pubmed ID: 33205255 Control of Insulin Release by Transient Receptor Potential Melastatin 3 (TRPM3) Ion Channels Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. Nov, 2020 | Pubmed ID: 33166100 L-type Blocker STIMulate Ca Entry in Synthetic VSMCs Cell Calcium. 11, 2020 | Pubmed ID: 32892148 Cardiomyocyte-Specific Deletion of Orai1 Reveals Its Protective Role in Angiotensin-II-Induced Pathological Cardiac Remodeling Cells. 04, 2020 | Pubmed ID: 32354146 Analysis of Mrgprb2 Receptor-Evoked Ca Signaling in Bone Marrow Derived (BMMC) and Peritoneal (PMC) Mast Cells of TRPC-Deficient Mice Frontiers in Immunology. 2020 | Pubmed ID: 32322252 Angiotensin-II-Evoked Ca Entry in Murine Cardiac Fibroblasts Does Not Depend on TRPC Channels Cells. 01, 2020 | Pubmed ID: 32013125 Assessment of PEEP-Ventilation and the Time Point of Parallel-Conductance Determination for Pressure-Volume Analysis Under β-Adrenergic Stimulation in Mice Frontiers in Cardiovascular Medicine. 2019 | Pubmed ID: 31111037 Methylglyoxal Evokes Acute Ca Transients in Distinct Cell Types and Increases Agonist-evoked Ca Entry in Endothelial Cells Via CRAC Channels Cell Calcium. 03, 2019 | Pubmed ID: 30658323 Compensatory Mechanisms for Methylglyoxal Detoxification in Experimental & Clinical Diabetes Molecular Metabolism. 12, 2018 | Pubmed ID: 30287091 Deletion of Orai2 Augments Endogenous CRAC Currents and Degranulation in Mast Cells Leading to Enhanced Anaphylaxis Cell Calcium. May, 2018 | Pubmed ID: 29604961 TRPC Proteins Contribute to Development of Diabetic Retinopathy and Regulate Glyoxalase 1 Activity and Methylglyoxal Accumulation Molecular Metabolism. Mar, 2018 | Pubmed ID: 29373286 Heteromeric Channels Formed by TRPC1, TRPC4 and TRPC5 Define Hippocampal Synaptic Transmission and Working Memory The EMBO Journal. 09, 2017 | Pubmed ID: 28790178 Dicarbonyls and Advanced Glycation End-Products in the Development of Diabetic Complications and Targets for Intervention International Journal of Molecular Sciences. May, 2017 | Pubmed ID: 28475116 TRPM4-mediated Control of FcεRI-evoked Ca(2+) Elevation Comprises Enhanced Plasmalemmal Trafficking of TRPM4 Channels in Connective Tissue Type Mast Cells Scientific Reports. 09, 2016 | Pubmed ID: 27624684 A Background Ca2+ Entry Pathway Mediated by TRPC1/TRPC4 is Critical for Development of Pathological Cardiac Remodelling European Heart Journal. Sep, 2015 | Pubmed ID: 26069213 Adenylyl Cyclase-mediated Effects Contribute to Increased Isoprenaline-induced Cardiac Contractility in TRPM4-deficient Mice Journal of Molecular and Cellular Cardiology. Sep, 2014 | Pubmed ID: 24972051 TRPC4- and TRPC4-containing Channels Handbook of Experimental Pharmacology. 2014 | Pubmed ID: 24756704 The Role of CGMP/cGKI Signalling and Trpc Channels in Regulation of Vascular Tone Cardiovascular Research. Nov, 2013 | Pubmed ID: 23832809 Canonical Transient Receptor Channel 5 (TRPC5) and TRPC1/4 Contribute to Seizure and Excitotoxicity by Distinct Cellular Mechanisms Molecular Pharmacology. Feb, 2013 | Pubmed ID: 23188715 Hjärtsvar på β-adrenerisk stimulering bestäms av analys av tryckvolymslinga Rebekka Medert*1,2, Lucas Bacmeister*1,2,3, Sebastian Segin*1,2,4, Marc Freichel1,2, Juan E. Camacho Londoño1,2 1Pharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, 2DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, 3Department of Internal Medicine III, University of Heidelberg, 4Department of Anesthesiology, University Hospital RWTH Aachen JoVE 62057 Medicine Isolering av Peritoneum-derived mastceller och deras funktionella karakterisering med Ca2 +-imaging och degranulering analyser Volodymyr Tsvilovskyy1, Alejandra Solis-Lopez1, Kathrin Öhlenschläger1, Marc Freichel1 1Institute of Pharmacology, Ruprecht-Karls Heidelberg University JoVE 57222 Immunology and Infection Kontraktilitet Mätningar på isolerade papillarmusklerna för utredning av Cardiac inotropi hos möss Sebastian Uhl1, Marc Freichel1, Ilka Mathar1 1Pharmakologisches Institut, Universität Heidelberg JoVE 53076 Biology
Hjärtsvar på β-adrenerisk stimulering bestäms av analys av tryckvolymslinga Rebekka Medert*1,2, Lucas Bacmeister*1,2,3, Sebastian Segin*1,2,4, Marc Freichel1,2, Juan E. Camacho Londoño1,2 1Pharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, 2DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, 3Department of Internal Medicine III, University of Heidelberg, 4Department of Anesthesiology, University Hospital RWTH Aachen JoVE 62057 Medicine
Isolering av Peritoneum-derived mastceller och deras funktionella karakterisering med Ca2 +-imaging och degranulering analyser Volodymyr Tsvilovskyy1, Alejandra Solis-Lopez1, Kathrin Öhlenschläger1, Marc Freichel1 1Institute of Pharmacology, Ruprecht-Karls Heidelberg University JoVE 57222 Immunology and Infection
Kontraktilitet Mätningar på isolerade papillarmusklerna för utredning av Cardiac inotropi hos möss Sebastian Uhl1, Marc Freichel1, Ilka Mathar1 1Pharmakologisches Institut, Universität Heidelberg JoVE 53076 Biology
