Mark Helm

Publications

• Identification of Modifications in Microbial, Native TRNA That Suppress Immunostimulatory Activity
  The Journal of Experimental Medicine. Feb, 2012  |   Pubmed ID: 22312113
• Dye Selection for Live Cell Imaging of Intact SiRNA
  Biological Chemistry. Dec, 2011  |   Pubmed ID: 22148896
• RNA Nucleotide Methylation
  Wiley Interdisciplinary Reviews. RNA. Sep-Oct, 2011  |   Pubmed ID: 21823225
• Single-molecule FRET Reveals a Cooperative Effect of Two Methyl Group Modifications in the Folding of Human Mitochondrial TRNA(Lys)
  Chemistry & Biology. Jul, 2011  |   Pubmed ID: 21802013
• Regulatory RNAs and Beyond
  EMBO Reports. Aug, 2011  |   Pubmed ID: 21760614
• Use of Specific Chemical Reagents for Detection of Modified Nucleotides in RNA
  Journal of Nucleic Acids. 2011  |   Pubmed ID: 21716696
• A Multifunctional Bioconjugate Module for Versatile Photoaffinity Labeling and Click Chemistry of RNA
  Nucleic Acids Research. Sep, 2011  |   Pubmed ID: 21646334
• Single-molecule FRET Studies of Counterion Effects on the Free Energy Landscape of Human Mitochondrial Lysine TRNA
  Biochemistry. Apr, 2011  |   Pubmed ID: 21375355
• A Post-labeling Approach for the Characterization and Quantification of RNA Modifications Based on Site-directed Cleavage by DNAzymes
  Methods in Molecular Biology (Clifton, N.J.). 2011  |   Pubmed ID: 21370054
• Measuring Single Small Molecule Binding Via Rupture Forces of a Split Aptamer
  Journal of the American Chemical Society. Feb, 2011  |   Pubmed ID: 21287983
• Expanding the Chemical Scope of RNA:methyltransferases to Site-specific Alkynylation of RNA for Click Labeling
  Nucleic Acids Research. Mar, 2011  |   Pubmed ID: 21037259
• RNA Methylation by Dnmt2 Protects Transfer RNAs Against Stress-induced Cleavage
  Genes & Development. Aug, 2010  |   Pubmed ID: 20679393
• TRNA Stabilization by Modified Nucleotides
  Biochemistry. Jun, 2010  |   Pubmed ID: 20459084
• Detection of RNA Modifications
  RNA Biology. Mar-Apr, 2010  |   Pubmed ID: 20224293
• A New Nuclear Function of the Entamoeba Histolytica Glycolytic Enzyme Enolase: the Metabolic Regulation of Cytosine-5 Methyltransferase 2 (Dnmt2) Activity
  PLoS Pathogens. Feb, 2010  |   Pubmed ID: 20174608
• Evidence-based Use of Second-generation Antipsychotics in a State Medicaid Pediatric Population, 2001-2005
  Psychiatric Services (Washington, D.C.). Feb, 2010  |   Pubmed ID: 20123816
• Formation of a Stalled Early Intermediate of Pseudouridine Synthesis Monitored by Real-time FRET
  RNA (New York, N.Y.). Mar, 2010  |   Pubmed ID: 20106954
• FRET Imaging of Cells Transfected with SiRNA/liposome Complexes
  Methods in Molecular Biology (Clifton, N.J.). 2010  |   Pubmed ID: 20013414
• 5-methylcytosine in RNA: Detection, Enzymatic Formation and Biological Functions
  Nucleic Acids Research. Mar, 2010  |   Pubmed ID: 20007150
• In Vivo Down-regulation of Mouse Brain Capillary P-glycoprotein: a Preliminary Investigation
  Neuroscience Letters. Oct, 2009  |   Pubmed ID: 19679165
• Good and Poor Adherence: Optimal Cut-point for Adherence Measures Using Administrative Claims Data
  Current Medical Research and Opinion. Sep, 2009  |   Pubmed ID: 19635045
• Effect of a Quaternary Pentamine on RNA Stabilization and Enzymatic Methylation
  Biological Chemistry. Sep, 2009  |   Pubmed ID: 19558320
• Prospective Validation of Eight Different Adherence Measures for Use with Administrative Claims Data Among Patients with Schizophrenia
  Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research. Sep, 2009  |   Pubmed ID: 19402852
• Preparation of Small Amounts of Sterile SiRNA-liposomes with High Entrapping Efficiency by Dual Asymmetric Centrifugation (DAC)
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Apr, 2009  |   Pubmed ID: 19124051
• An Empirical Basis for Standardizing Adherence Measures Derived from Administrative Claims Data Among Diabetic Patients
  Medical Care. Nov, 2008  |   Pubmed ID: 18953222
• RNA Intramolecular Dynamics by Single-molecule FRET
  Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [et Al.]. Sep, 2008  |   Pubmed ID: 18819081
• Human DNMT2 Methylates TRNA(Asp) Molecules Using a DNA Methyltransferase-like Catalytic Mechanism
  RNA (New York, N.Y.). Aug, 2008  |   Pubmed ID: 18567810
• Sculpting an RNA Conformational Energy Landscape by a Methyl Group Modification--a Single-molecule FRET Study
  Angewandte Chemie (International Ed. in English). 2008  |   Pubmed ID: 18449867
• Use of DNAzymes for Site-specific Analysis of Ribonucleotide Modifications
  RNA (New York, N.Y.). Jan, 2008  |   Pubmed ID: 17998290
• Readout of Micromechanical Cantilever Sensor Arrays by Fabry-Perot Interferometry
  The Review of Scientific Instruments. Oct, 2007  |   Pubmed ID: 17979440
• A Methyl Group Controls Conformational Equilibrium in Human Mitochondrial TRNA(Lys)
  Journal of the American Chemical Society. Nov, 2007  |   Pubmed ID: 17941640
• Surveillance of SiRNA Integrity by FRET Imaging
  Nucleic Acids Research. 2007  |   Pubmed ID: 17890733
• Mg2+-dependent Folding of a Diels-Alderase Ribozyme Probed by Single-molecule FRET Analysis
  Nucleic Acids Research. 2007  |   Pubmed ID: 17344321
• Molecular Dysfunction Associated with the Human Mitochondrial 3302A>G Mutation in the MTTL1 (mt-tRNALeu(UUR)) Gene
  Nucleic Acids Research. 2006  |   Pubmed ID: 17130166
• Post-transcriptional Nucleotide Modification and Alternative Folding of RNA
  Nucleic Acids Research. 2006  |   Pubmed ID: 16452298
• Optimizing Splinted Ligation of Highly Structured Small RNAs
  RNA (New York, N.Y.). Dec, 2005  |   Pubmed ID: 16251384
• A New Mechanism for MtDNA Pathogenesis: Impairment of Post-transcriptional Maturation Leads to Severe Depletion of Mitochondrial TRNASer(UCN) Caused by T7512C and G7497A Point Mutations
  Nucleic Acids Research. 2005  |   Pubmed ID: 16199753
• Allosterically Activated Diels-Alder Catalysis by a Ribozyme
  Journal of the American Chemical Society. Aug, 2005  |   Pubmed ID: 16045328
• Aminoacylation Properties of Pathology-related Human Mitochondrial TRNA(Lys) Variants
  RNA (New York, N.Y.). May, 2004  |   Pubmed ID: 15100439
• Nuclear Control of Cloverleaf Structure of Human Mitochondrial TRNA(Lys)
  Journal of Molecular Biology. Mar, 2004  |   Pubmed ID: 15019776
• A Monomer-to-trimer Transition of the Human Mitochondrial Transcription Termination Factor (mTERF) is Associated with a Loss of in Vitro Activity
  The Journal of Biological Chemistry. Apr, 2004  |   Pubmed ID: 14744862
• RNA Sex
  Chemistry & Biology. Dec, 2003  |   Pubmed ID: 14700622
• Variability of Substrate Specificity of Serum Antibodies Obtained from Patients with Different Autoimmune and Viral Diseases in Reaction of TRNA Hydrolysis
  Russian Journal of Immunology : RJI : Official Journal of Russian Society of Immunology. Apr, 1999  |   Pubmed ID: 12687113