Martin Krönke Institute for Medical Microbiology, Immunology and Hygiene, Faculty of Medicine and University Hospital Cologne University of Cologne Biography Publications Institution JoVE Articles Martin Krönke has not added a biography. If you are Martin Krönke and would like to personalize this page please email our Author Liaison for assistance. Publications A Tissue-specific Screen of Ceramide Expression in Aged Mice Identifies Ceramide Synthase-1 and Ceramide Synthase-5 As Potential Regulators of Fiber Size and Strength in Skeletal Muscle Aging Cell. Nov, 2019 | Pubmed ID: 31692231 Emergence of AnnexinVpos CD31neg CD42blow/neg Extracellular Vesicles in Plasma of Humans at Extreme Altitude PloS One. 2019 | Pubmed ID: 31369589 Generation and Selection of Antibodies for a Novel Immunochromatographic Lateral Flow Test to Rapidly Identify OXA-23-like-mediated Carbapenem Resistance in Acinetobacter Baumannii Journal of Medical Microbiology. Jul, 2019 | Pubmed ID: 31188094 Mitochondrial Reactive Oxygen Species Enable Proinflammatory Signaling Through Disulfide Linkage of NEMO Science Signaling. 02, 2019 | Pubmed ID: 30755476 The β Integrin Mac-1 Induces Protective LC3-Associated Phagocytosis of Listeria Monocytogenes Cell Host & Microbe. Mar, 2018 | Pubmed ID: 29544096 Hypoxia-induced Changes in Plasma Micro-RNAs Correlate with Pulmonary Artery Pressure at High Altitude American Journal of Physiology. Lung Cellular and Molecular Physiology. 01, 2018 | Pubmed ID: 28971974 Type I Interferon Enhances Necroptosis of Typhimurium-infected Macrophages by Impairing Antioxidative Stress Responses The Journal of Cell Biology. 12, 2017 | Pubmed ID: 29055012 Salmonella Typhimurium Disrupts Sirt1/AMPK Checkpoint Control of MTOR to Impair Autophagy PLoS Pathogens. Feb, 2017 | Pubmed ID: 28192515 Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids Cell Stem Cell. Mar, 2017 | Pubmed ID: 28132835 P22phox C242T Single-Nucleotide Polymorphism Inhibits Inflammatory Oxidative Damage to Endothelial Cells and Vessels Circulation. Jun, 2016 | Pubmed ID: 27162237 Endogenous Il10 Alleviates the Systemic Antiviral Cellular Immune Response and T Cell-mediated Immunopathology in Select Organs of Acutely LCMV-infected Mice The American Journal of Pathology. Nov, 2015 | Pubmed ID: 26506472 IAP Antagonization Promotes Inflammatory Destruction of Vascular Endothelium EMBO Reports. Jun, 2015 | Pubmed ID: 25825408 Ceramide Synthase 4 Regulates Stem Cell Homeostasis and Hair Follicle Cycling The Journal of Investigative Dermatology. Jun, 2015 | Pubmed ID: 25705848 BID-dependent Release of Mitochondrial SMAC Dampens XIAP-mediated Immunity Against Shigella The EMBO Journal. Oct, 2014 | Pubmed ID: 25056906 Embelin Inhibits Endothelial Mitochondrial Respiration and Impairs Neoangiogenesis During Tumor Growth and Wound Healing EMBO Molecular Medicine. May, 2014 | Pubmed ID: 24648500 Riboflavin (vitamin B2 ) Deficiency Impairs NADPH Oxidase 2 (Nox2) Priming and Defense Against Listeria Monocytogenes European Journal of Immunology. Mar, 2014 | Pubmed ID: 24272050 Second Mitochondria-derived Activator of Caspase (SMAC) Mimetic Potentiates Tumor Susceptibility Toward Natural Killer Cell-mediated Killing Leukemia & Lymphoma. Mar, 2014 | Pubmed ID: 23697877 On the Antibiotic and Antifungal Activity of Pestalone, Pestalachloride A, and Structurally Related Compounds Journal of Natural Products. Aug, 2013 | Pubmed ID: 23905700 Soluble Ligands for NK Cell Receptors Promote Evasion of Chronic Lymphocytic Leukemia Cells from NK Cell Anti-tumor Activity Blood. May, 2013 | Pubmed ID: 23509156 Therapeutic Concentrations of Antibiotics Inhibit Shiga Toxin Release from Enterohemorrhagic E. Coli O104:H4 from the 2011 German Outbreak BMC Microbiology. Aug, 2012 | Pubmed ID: 22853739 WIPI-1 Positive Autophagosome-Like Vesicles Entrap Pathogenic Staphylococcus Aureus for Lysosomal Degradation International Journal of Cell Biology. 2012 | Pubmed ID: 22829830 Factor Associated with Neutral Sphingomyelinase Activity Mediates Navigational Capacity of Leukocytes Responding to Wounds and Infection: Live Imaging Studies in Zebrafish Larvae Journal of Immunology (Baltimore, Md. : 1950). Aug, 2012 | Pubmed ID: 22802420 Listeria Monocytogenes Infection in Macrophages Induces Vacuolar-dependent Host MiRNA Response PloS One. 2011 | Pubmed ID: 22114673 Anti-inflammatory Arene--chromium Complexes Acting As Specific Inhibitors of NOD2 Signalling ChemMedChem. Dec, 2010 | Pubmed ID: 20973121 Selection of Potent Non-toxic Inhibitory Sequences from a Randomized HIV-1 Specific Lentiviral Short Hairpin RNA Library PloS One. Oct, 2010 | Pubmed ID: 20949027 The Proteasome Inhibitor Bortezomib Sensitizes Melanoma Cells Toward Adoptive CTL Attack Cancer Research. Mar, 2010 | Pubmed ID: 20179203 Immunologic Hurdles of Therapeutic Stem Cell Transplantation Biological Chemistry. Oct, 2009 | Pubmed ID: 19642871 Riboflavin Kinase Couples TNF Receptor 1 to NADPH Oxidase Nature. Aug, 2009 | Pubmed ID: 19641494 Acid Sphingomyelinase is a Key Regulator of Cytotoxic Granule Secretion by Primary T Lymphocytes Nature Immunology. Jul, 2009 | Pubmed ID: 19525969 Looking Beyond Death: a Morphogenetic Role for the TNF Signalling Pathway Journal of Cell Science. Jun, 2009 | Pubmed ID: 19494121 Proteomics-based Identification of Anchorless Cell Wall Proteins As Vaccine Candidates Against Staphylococcus Aureus Infection and Immunity. Jul, 2009 | Pubmed ID: 19364833 Large Scale Multiplex PCR Improves Pathogen Detection by DNA Microarrays BMC Microbiology. Jan, 2009 | Pubmed ID: 19121223 Role of Natural-killer Group 2 Member D Ligands and Intercellular Adhesion Molecule 1 in Natural Killer Cell-mediated Lysis of Murine Embryonic Stem Cells and Embryonic Stem Cell-derived Cardiomyocytes Stem Cells (Dayton, Ohio). Feb, 2009 | Pubmed ID: 18988711 Gene Transfer of Hodgkin Cell Lines Via Multivalent Anti-CD30 ScFv Displaying Bacteriophage BMC Molecular Biology. Apr, 2008 | Pubmed ID: 18416816 Fusogenicity of Membranes: the Impact of Acid Sphingomyelinase on Innate Immune Responses Immunobiology. 2008 | Pubmed ID: 18406376 PtdIns(4,5)P-restricted Plasma Membrane Localization of FAN is Involved in TNF-induced Actin Reorganization The EMBO Journal. Jul, 2007 | Pubmed ID: 17599063 Transport of Streptococcus Pneumoniae Capsular Polysaccharide in MHC Class II Tubules PLoS Pathogens. Mar, 2007 | Pubmed ID: 17367207 Serpin-6 Expression Protects Embryonic Stem Cells from Lysis by Antigen-specific CTL Journal of Immunology (Baltimore, Md. : 1950). Mar, 2007 | Pubmed ID: 17339433 NF-kappaB-independent Down-regulation of XIAP by Bortezomib Sensitizes HL B Cells Against Cytotoxic Drugs Blood. May, 2007 | Pubmed ID: 17185461 Rapid Identification, Virulence Analysis and Resistance Profiling of Staphylococcus Aureus by Gene Segment-based DNA Microarrays: Application to Blood Culture Post-processing Journal of Microbiological Methods. Mar, 2007 | Pubmed ID: 17141897 Staphylococcus Aureus Subvert Autophagy for Induction of Caspase-independent Host Cell Death The Journal of Biological Chemistry. Jan, 2007 | Pubmed ID: 17135247 Indoleamine 2,3-dioxygenase-expressing Dendritic Cells Form Suppurative Granulomas Following Listeria Monocytogenes Infection The Journal of Clinical Investigation. Dec, 2006 | Pubmed ID: 17111046 Inhibition of TNF Receptor 1 Internalization by Adenovirus 14.7K As a Novel Immune Escape Mechanism The Journal of Clinical Investigation. Nov, 2006 | Pubmed ID: 17024246 Subinhibitory Quinupristin/dalfopristin Attenuates Virulence of Staphylococcus Aureus The Journal of Antimicrobial Chemotherapy. Sep, 2006 | Pubmed ID: 16895938 XIAP Targeting Sensitizes Hodgkin Lymphoma Cells for Cytolytic T-cell Attack Blood. Nov, 2006 | Pubmed ID: 16868249 Identification and Characterization of Bacterial Pathogens Causing Bloodstream Infections by DNA Microarray Journal of Clinical Microbiology. Jul, 2006 | Pubmed ID: 16825354 Novel Tumor Necrosis Factor-responsive Mammalian Neutral Sphingomyelinase-3 is a C-tail-anchored Protein The Journal of Biological Chemistry. May, 2006 | Pubmed ID: 16517606 Targeting of HIV-1 Tat Traffic and Function by Transduction-competent Single Chain Antibodies Vaccine. Apr, 2006 | Pubmed ID: 16497417 Acid Sphingomyelinase is Indispensable for UV Light-induced Bax Conformational Change at the Mitochondrial Membrane The Journal of Biological Chemistry. May, 2005 | Pubmed ID: 15743760 Subinhibitory Concentrations of Linezolid Reduce Staphylococcus Aureus Virulence Factor Expression Antimicrobial Agents and Chemotherapy. Feb, 2004 | Pubmed ID: 14742208 XIAP-mediated Caspase Inhibition in Hodgkin's Lymphoma-derived B Cells The Journal of Experimental Medicine. Jul, 2003 | Pubmed ID: 12874265 T Lymphoid Differentiation in Human Bone Marrow Proceedings of the National Academy of Sciences of the United States of America. May, 2003 | Pubmed ID: 12738882 Detection of Chlamydia Pneumoniae-specific Antibodies Binding to the VD2 and VD3 Regions of the Major Outer Membrane Protein Journal of Clinical Microbiology. May, 2003 | Pubmed ID: 12734234 Silencing of B Cell Receptor Signals in Human Naive B Cells The Journal of Experimental Medicine. Nov, 2002 | Pubmed ID: 12438421 Role of Caspases in TNF-mediated Regulation of CPLA(2) FEBS Letters. Oct, 2002 | Pubmed ID: 12401196 Crystal Structure of the BEACH Domain Reveals an Unusual Fold and Extensive Association with a Novel PH Domain The EMBO Journal. Sep, 2002 | Pubmed ID: 12234919 Molecular Portraits of B Cell Lineage Commitment Proceedings of the National Academy of Sciences of the United States of America. Jul, 2002 | Pubmed ID: 12119411 Identification and Discrimination of Staphylococcus Aureus Strains Using Matrix-assisted Laser Desorption/ionization-time of Flight Mass Spectrometry Proteomics. Jun, 2002 | Pubmed ID: 12112858 Identification of Staphylococcus Aureus Exotoxins by Combined Sodium Dodecyl Sulfate Gel Electrophoresis and Matrix-assisted Laser Desorption/ Ionization-time of Flight Mass Spectrometry Proteomics. Jun, 2002 | Pubmed ID: 12112857 Human Endothelial Cell Activation and Mediator Release in Response to Listeria Monocytogenes Virulence Factors Infection and Immunity. Feb, 2001 | Pubmed ID: 11159983 Highly Efficient Transfection of Primary Macrophages with In Vitro Transcribed mRNA Marc Herb1, Alina Farid1, Alexander Gluschko1, Martin Krönke1,2,3,4, Michael Schramm1 1Institute for Medical Microbiology, Immunology and Hygiene, Faculty of Medicine and University Hospital Cologne, University of Cologne, 2Center for Molecular Medicine Cologne, 3Cologne Cluster of Excellence on Cellular Stress Responses in Aging-associated Diseases (CECAD), 4German Center for Infection Research (DZIF) JoVE 60143 Immunology and Infection
Highly Efficient Transfection of Primary Macrophages with In Vitro Transcribed mRNA Marc Herb1, Alina Farid1, Alexander Gluschko1, Martin Krönke1,2,3,4, Michael Schramm1 1Institute for Medical Microbiology, Immunology and Hygiene, Faculty of Medicine and University Hospital Cologne, University of Cologne, 2Center for Molecular Medicine Cologne, 3Cologne Cluster of Excellence on Cellular Stress Responses in Aging-associated Diseases (CECAD), 4German Center for Infection Research (DZIF) JoVE 60143 Immunology and Infection
