Mathias Ziegler

Publications

• SIRT2 Inactivation Reveals a Subset of Hyperacetylated Perinuclear Microtubules Inaccessible to HDAC6
  Journal of Cell Science. Aug, 2016  |   Pubmed ID: 27311481
• Subcellular Distribution of NAD+ Between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells
  The Journal of Biological Chemistry. Nov, 2015  |   Pubmed ID: 26432643
• Generation, Release, and Uptake of the NAD Precursor Nicotinic Acid Riboside by Human Cells
  The Journal of Biological Chemistry. Nov, 2015  |   Pubmed ID: 26385918
• The Human NAD Metabolome: Functions, Metabolism and Compartmentalization
  Critical Reviews in Biochemistry and Molecular Biology. 2015  |   Pubmed ID: 25837229
• An Organellar Nα-acetyltransferase, Naa60, Acetylates Cytosolic N Termini of Transmembrane Proteins and Maintains Golgi Integrity
  Cell Reports. Mar, 2015  |   Pubmed ID: 25732826
• NAD Kinase Controls Animal NADP Biosynthesis and is Modulated Via Evolutionarily Divergent Calmodulin-dependent Mechanisms
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2015  |   Pubmed ID: 25605906
• The PHD Finger of P300 Influences Its Ability to Acetylate Histone and Non-histone Targets
  Journal of Molecular Biology. Dec, 2014  |   Pubmed ID: 25158095
• Sequence Divergence and Diversity Suggests Ongoing Functional Diversification of Vertebrate NAD Metabolism
  DNA Repair. Nov, 2014  |   Pubmed ID: 25084685
• Separating NADH and NADPH Fluorescence in Live Cells and Tissues Using FLIM
  Nature Communications. May, 2014  |   Pubmed ID: 24874098
• Regulation of SIRT2-dependent α-tubulin Deacetylation by Cellular NAD Levels
  DNA Repair. Nov, 2014  |   Pubmed ID: 24814981
• Carbohydrate Metabolism During Vertebrate Appendage Regeneration: What is Its Role? How is It Regulated?: A Postulation That Regenerating Vertebrate Appendages Facilitate Glycolytic and Pentose Phosphate Pathways to Fuel Macromolecule Biosynthesis
  BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Jan, 2014  |   Pubmed ID: 24264888
• Constitutive Nuclear Localization of an Alternatively Spliced Sirtuin-2 Isoform
  Journal of Molecular Biology. Apr, 2014  |   Pubmed ID: 24177535
• NAD Biosynthesis in Humans--enzymes, Metabolites and Therapeutic Aspects
  Current Topics in Medicinal Chemistry. 2013  |   Pubmed ID: 24171775
• Model of Tryptophan Metabolism, Readily Scalable Using Tissue-specific Gene Expression Data
  The Journal of Biological Chemistry. Nov, 2013  |   Pubmed ID: 24129579
• Physiology of ADP-ribosylation
  The FEBS Journal. Aug, 2013  |   Pubmed ID: 23773547
• Pharmacology of ADP-ribosylation
  The FEBS Journal. Aug, 2013  |   Pubmed ID: 23763848
• NAD and ADP-ribose Metabolism in Mitochondria
  The FEBS Journal. Aug, 2013  |   Pubmed ID: 23617329
• The NAD Metabolome--a Key Determinant of Cancer Cell Biology
  Nature Reviews. Cancer. Nov, 2012  |   Pubmed ID: 23018234
• ADP-ribosylhydrolase 3 (ARH3), Not Poly(ADP-ribose) Glycohydrolase (PARG) Isoforms, is Responsible for Degradation of Mitochondrial Matrix-associated Poly(ADP-ribose)
  The Journal of Biological Chemistry. May, 2012  |   Pubmed ID: 22433848
• NAD(+) Biosynthesis and Salvage--a Phylogenetic Perspective
  The FEBS Journal. Sep, 2012  |   Pubmed ID: 22404877
• Pathway Analysis of NAD+ Metabolism
  The Biochemical Journal. Oct, 2011  |   Pubmed ID: 21729004
• Progress in the Function and Regulation of ADP-Ribosylation
  Science Signaling. 2011  |   Pubmed ID: 21610250
• Pathways and Subcellular Compartmentation of NAD Biosynthesis in Human Cells: from Entry of Extracellular Precursors to Mitochondrial NAD Generation
  The Journal of Biological Chemistry. Jun, 2011  |   Pubmed ID: 21504897
• Compartmentation of NAD+-dependent Signalling
  FEBS Letters. Jun, 2011  |   Pubmed ID: 21443875
• Isoform-specific Targeting and Interaction Domains in Human Nicotinamide Mononucleotide Adenylyltransferases
  The Journal of Biological Chemistry. Jun, 2010  |   Pubmed ID: 20388704
• The Phosphate Makes a Difference: Cellular Functions of NADP
  Redox Report : Communications in Free Radical Research. 2010  |   Pubmed ID: 20196923
• Visualization of Subcellular NAD Pools and Intra-organellar Protein Localization by Poly-ADP-ribose Formation
  Cellular and Molecular Life Sciences : CMLS. Feb, 2010  |   Pubmed ID: 19902144
• Human Naa50p (Nat5/San) Displays Both Protein N Alpha- and N Epsilon-acetyltransferase Activity
  The Journal of Biological Chemistry. Nov, 2009  |   Pubmed ID: 19744929
• Application of Reverse-phase HPLC to Quantify Oligopeptide Acetylation Eliminates Interference from Unspecific Acetyl CoA Hydrolysis
  BMC Proceedings. Aug, 2009  |   Pubmed ID: 19660098
• The NMN/NaMN Adenylyltransferase (NMNAT) Protein Family
  Frontiers in Bioscience (Landmark Edition). Jan, 2009  |   Pubmed ID: 19273075
• Proteomic Response of Human Neuroblastoma Cells to Azaspiracid-1
  Journal of Proteomics. May, 2009  |   Pubmed ID: 19269354
• Reconstitution of Yeast Silent Chromatin: Multiple Contact Sites and O-AADPR Binding Load SIR Complexes Onto Nucleosomes in Vitro
  Molecular Cell. Feb, 2009  |   Pubmed ID: 19217406
• Emerging Roles of NAD+ and Its Metabolites in Cell Signaling
  Science Signaling. 2009  |   Pubmed ID: 19211509
• Application of a Coupled Enzyme Assay to Characterize Nicotinamide Riboside Kinases
  Analytical Biochemistry. Feb, 2009  |   Pubmed ID: 19027704
• Inhibition of the Glucosyltransferase Activity of Clostridial Rho/Ras-glucosylating Toxins by Castanospermine
  FEBS Letters. Jun, 2008  |   Pubmed ID: 18505687
• Conformational Changes and Reaction of Clostridial Glycosylating Toxins
  Journal of Molecular Biology. Apr, 2008  |   Pubmed ID: 18325534
• Designed Protein-protein Association
  Science (New York, N.Y.). Jan, 2008  |   Pubmed ID: 18187656
• Functional Localization of Two Poly(ADP-ribose)-degrading Enzymes to the Mitochondrial Matrix
  Molecular and Cellular Biology. Jan, 2008  |   Pubmed ID: 17991898
• Refinement of a Radioreceptor Binding Assay for Nicotinic Acid Adenine Dinucleotide Phosphate
  Analytical Biochemistry. Dec, 2007  |   Pubmed ID: 17919448
• NAD Kinase Levels Control the NADPH Concentration in Human Cells
  The Journal of Biological Chemistry. Nov, 2007  |   Pubmed ID: 17855339
• Regulation of Poly(ADP-ribose) Polymerase 1 Activity by the Phosphorylation State of the Nuclear NAD Biosynthetic Enzyme NMN Adenylyl Transferase 1
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2007  |   Pubmed ID: 17360427
• The Power to Reduce: Pyridine Nucleotides--small Molecules with a Multitude of Functions
  The Biochemical Journal. Mar, 2007  |   Pubmed ID: 17295611
• Emerging Functions of Extracellular Pyridine Nucleotides
  Molecular Medicine (Cambridge, Mass.). Nov-Dec, 2006  |   Pubmed ID: 17380199
• Time Sensing by NAADP Receptors
  The Biochemical Journal. Jul, 2006  |   Pubmed ID: 16551267
• A Vital Link Between Energy and Signal Transduction
  The FEBS Journal. Sep, 2005  |   Pubmed ID: 16156778
• Subcellular Compartmentation and Differential Catalytic Properties of the Three Human Nicotinamide Mononucleotide Adenylyltransferase Isoforms
  The Journal of Biological Chemistry. Oct, 2005  |   Pubmed ID: 16118205
• Poly(ADP-ribosylation) and Genomic Stability
  Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Jun, 2005  |   Pubmed ID: 15959554
• NAD+ Surfaces Again
  The Biochemical Journal. Sep, 2004  |   Pubmed ID: 15352307
• The New Life of a Centenarian: Signalling Functions of NAD(P)
  Trends in Biochemical Sciences. Mar, 2004  |   Pubmed ID: 15003268
• ATP-dependent Selection Between Single Nucleotide and Long Patch Base Excision Repair
  DNA Repair. Oct, 2003  |   Pubmed ID: 13679148
• Crystal Structure of Human Nicotinamide Mononucleotide Adenylyltransferase in Complex with NMN
  FEBS Letters. Apr, 2002  |   Pubmed ID: 11959140
• Crystallization and Preliminary X-ray Analysis of Human Nicotinamide Mononucleotide Adenylyltransferase (NMNAT)
  Acta Crystallographica. Section D, Biological Crystallography. Jan, 2002  |   Pubmed ID: 11752792