Matthew W. Kelley Laboratory of Cochlear Development National Institute on Deafness and Other Communication Disorders Biography Publications Institution JoVE Articles Matthew W. Kelley has not added a biography. If you are Matthew W. Kelley and would like to personalize this page please email our Author Liaison for assistance. Publications Pou3f4-mediated Regulation of Ephrin-b2 Controls Temporal Bone Development in the Mouse PloS One. 2014 | Pubmed ID: 25299585 Retinoic Acid Signalling Regulates the Development of Tonotopically Patterned Hair Cells in the Chicken Cochlea Nature Communications. 2014 | Pubmed ID: 24845860 A Gradient of Bmp7 Specifies the Tonotopic Axis in the Developing Inner Ear Nature Communications. 2014 | Pubmed ID: 24845721 Wdpcp, a PCP Protein Required for Ciliogenesis, Regulates Directional Cell Migration and Cell Polarity by Direct Modulation of the Actin Cytoskeleton PLoS Biology. Nov, 2013 | Pubmed ID: 24302887 Expression and Function of Scleraxis in the Developing Auditory System PloS One. 2013 | Pubmed ID: 24058692 Expression of Insulin-like Growth Factor Binding Proteins During Mouse Cochlear Development Developmental Dynamics : an Official Publication of the American Association of Anatomists. Oct, 2013 | Pubmed ID: 23813480 Making Connections in the Inner Ear: Recent Insights into the Development of Spiral Ganglion Neurons and Their Connectivity with Sensory Hair Cells Seminars in Cell & Developmental Biology. May, 2013 | Pubmed ID: 23660234 Making Sense with Thyroid Hormone--the Role of T(3) in Auditory Development Nature Reviews. Endocrinology. May, 2013 | Pubmed ID: 23529044 Thyroid Hormone Increases Fibroblast Growth Factor Receptor Expression and Disrupts Cell Mechanics in the Developing Organ of Corti BMC Developmental Biology. 2013 | Pubmed ID: 23394545 The Atoh1-lineage Gives Rise to Hair Cells and Supporting Cells Within the Mammalian Cochlea Developmental Biology. Apr, 2013 | Pubmed ID: 23318633 Cilia, Wnt Signaling, and the Cytoskeleton Cilia. 2012 | Pubmed ID: 23351924 Fibroblast Growth Factor Receptor 3 Regulates Microtubule Formation and Cell Surface Mechanical Properties in the Developing Organ of Corti Bioarchitecture. Nov-Dec, 2012 | Pubmed ID: 23267415 Planar Cell Polarity in the Inner Ear Current Topics in Developmental Biology. 2012 | Pubmed ID: 23140627 A Dual Function for Canonical Wnt/β-catenin Signaling in the Developing Mammalian Cochlea Development (Cambridge, England). Dec, 2012 | Pubmed ID: 23132246 Gipc1 Has a Dual Role in Vangl2 Trafficking and Hair Bundle Integrity in the Inner Ear Development (Cambridge, England). Oct, 2012 | Pubmed ID: 22991442 Molecular Mechanisms of Inner Ear Development Cold Spring Harbor Perspectives in Biology. Aug, 2012 | Pubmed ID: 22855724 Fgf Signaling Regulates Development and Transdifferentiation of Hair Cells and Supporting Cells in the Basilar Papilla Hearing Research. Jul, 2012 | Pubmed ID: 22575790 Cytoskeletal Changes in Actin and Microtubules Underlie the Developing Surface Mechanical Properties of Sensory and Supporting Cells in the Mouse Cochlea Development (Cambridge, England). Jun, 2012 | Pubmed ID: 22573615 Stem Cell Therapy for the Inner Ear: Recent Advances and Future Directions Trends in Amplification. Mar, 2012 | Pubmed ID: 22514095 Combining Cep290 and Mkks Ciliopathy Alleles in Mice Rescues Sensory Defects and Restores Ciliogenesis The Journal of Clinical Investigation. Apr, 2012 | Pubmed ID: 22446187 Otic Mesenchyme Cells Regulate Spiral Ganglion Axon Fasciculation Through a Pou3f4/EphA4 Signaling Pathway Neuron. Jan, 2012 | Pubmed ID: 22243746 Examining Planar Cell Polarity in the Mammalian Cochlea Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22218900 Insulin-like Growth Factor Signaling Regulates the Timing of Sensory Cell Differentiation in the Mouse Cochlea The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2011 | Pubmed ID: 22159122 Loss of Bardet-Biedl Syndrome Protein-8 (BBS8) Perturbs Olfactory Function, Protein Localization, and Axon Targeting Proceedings of the National Academy of Sciences of the United States of America. Jun, 2011 | Pubmed ID: 21646512 Response to a Letter to the Editor Hearing Research. Oct, 2011 | Pubmed ID: 21600274 Rbpj Regulates Development of Prosensory Cells in the Mammalian Inner Ear Developmental Biology. May, 2011 | Pubmed ID: 21420948 Development of Tonotopy in the Auditory Periphery Hearing Research. Jun, 2011 | Pubmed ID: 21276841 CD44 is a Marker for the Outer Pillar Cells in the Early Postnatal Mouse Inner Ear Journal of the Association for Research in Otolaryngology : JARO. Sep, 2010 | Pubmed ID: 20386946 Transfection of Mouse Cochlear Explants by Electroporation Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [et Al.]. Apr, 2010 | Pubmed ID: 20373505 Sox2 Induces Neuronal Formation in the Developing Mammalian Cochlea The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2010 | Pubmed ID: 20071536 Specification of Cell Fate in the Mammalian Cochlea Birth Defects Research. Part C, Embryo Today : Reviews. Sep, 2009 | Pubmed ID: 19750520 Regulation of Cell Fate and Patterning in the Developing Mammalian Cochlea Current Opinion in Otolaryngology & Head and Neck Surgery. Oct, 2009 | Pubmed ID: 19623076 Building the World's Best Hearing Aid; Regulation of Cell Fate in the Cochlea Current Opinion in Genetics & Development. Aug, 2009 | Pubmed ID: 19604683 Myosin II Regulates Extension, Growth and Patterning in the Mammalian Cochlear Duct Development (Cambridge, England). Jun, 2009 | Pubmed ID: 19439495 Sox2 Signaling in Prosensory Domain Specification and Subsequent Hair Cell Differentiation in the Developing Cochlea Proceedings of the National Academy of Sciences of the United States of America. Nov, 2008 | Pubmed ID: 19011097 Hedgehog Signaling Regulates Sensory Cell Formation and Auditory Function in Mice and Humans The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2008 | Pubmed ID: 18632939 Leading Wnt Down a PCP Path: Cthrc1 Acts As a Coreceptor in the Wnt-PCP Pathway Developmental Cell. Jul, 2008 | Pubmed ID: 18606135 Jxc1/Sobp, Encoding a Nuclear Zinc Finger Protein, is Critical for Cochlear Growth, Cell Fate, and Patterning of the Organ of Corti The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2008 | Pubmed ID: 18579736 Has Hair Cell Loss MET Its Match? Proceedings of the National Academy of Sciences of the United States of America. Oct, 2007 | Pubmed ID: 17925436 Cellular Commitment and Differentiation in the Organ of Corti The International Journal of Developmental Biology. 2007 | Pubmed ID: 17891718 Fgf8 Induces Pillar Cell Fate and Regulates Cellular Patterning in the Mammalian Cochlea Development (Cambridge, England). Aug, 2007 | Pubmed ID: 17634195 Disruption of Fibroblast Growth Factor Receptor 3 Signaling Results in Defects in Cellular Differentiation, Neuronal Patterning, and Hearing Impairment Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jul, 2007 | Pubmed ID: 17557302 Lhx3, a LIM Domain Transcription Factor, is Regulated by Pou4f3 in the Auditory but Not in the Vestibular System The European Journal of Neuroscience. Feb, 2007 | Pubmed ID: 17331196 Myosin VI and VIIa Distribution Among Inner Ear Epithelia in Diverse Fishes Hearing Research. Feb, 2007 | Pubmed ID: 17204383 Regulation of Cell Fate in the Sensory Epithelia of the Inner Ear Nature Reviews. Neuroscience. Nov, 2006 | Pubmed ID: 17053809 Noncanonical Wnt Signaling and Neural Polarity Annual Review of Neuroscience. 2006 | Pubmed ID: 16776590 Asymmetric Localization of Vangl2 and Fz3 Indicate Novel Mechanisms for Planar Cell Polarity in Mammals The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2006 | Pubmed ID: 16687519 Hair Cell Development: Commitment Through Differentiation Brain Research. May, 2006 | Pubmed ID: 16626654 Inhibitors of Differentiation and DNA Binding (Ids) Regulate Math1 and Hair Cell Formation During the Development of the Organ of Corti The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2006 | Pubmed ID: 16407553 Planar Cell Polarity and a Potential Role for a Wnt Morphogen Gradient in Stereociliary Bundle Orientation in the Mammalian Inner Ear Journal of Neurobiology. Sep, 2005 | Pubmed ID: 16041762 Math1 Regulates Development of the Sensory Epithelium in the Mammalian Cochlea Nature Neuroscience. Dec, 2004 | Pubmed ID: 15543141 From Placode to Polarization: New Tunes in Inner Ear Development Development (Cambridge, England). Sep, 2004 | Pubmed ID: 15319325 Transcription Profiling of Inner Ears from Pou4f3(ddl/ddl) Identifies Gfi1 As a Target of the Pou4f3 Deafness Gene Human Molecular Genetics. Sep, 2004 | Pubmed ID: 15254021 Cellular Growth and Rearrangement During the Development of the Mammalian Organ of Corti Developmental Dynamics : an Official Publication of the American Association of Anatomists. Apr, 2004 | Pubmed ID: 15042704 Vascular Development in the Retina and Inner Ear: Control by Norrin and Frizzled-4, a High-affinity Ligand-receptor Pair Cell. Mar, 2004 | Pubmed ID: 15035989 Hearing Loss and Retarded Cochlear Development in Mice Lacking Type 2 Iodothyronine Deiodinase Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 14993610 Cell Adhesion Molecules During Inner Ear and Hair Cell Development, Including Notch and Its Ligands Current Topics in Developmental Biology. 2003 | Pubmed ID: 14674486 Analysis of Nuclear Receptor Function in the Mouse Auditory System Methods in Enzymology. 2003 | Pubmed ID: 14631859 Planar and Vertical Signals Control Cellular Differentiation and Patterning in the Mammalian Cochlea The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2003 | Pubmed ID: 14561877 Exposing the Roots of Hair Cell Regeneration in the Ear Nature Medicine. Oct, 2003 | Pubmed ID: 14520370 Identification of Vangl2 and Scrb1 As Planar Polarity Genes in Mammals Nature. May, 2003 | Pubmed ID: 12724779 Wnt Signaling Mediates Reorientation of Outer Hair Cell Stereociliary Bundles in the Mammalian Cochlea Development (Cambridge, England). Jun, 2003 | Pubmed ID: 12702652 Determination and Commitment of Mechanosensory Hair Cells TheScientificWorldJournal. Apr, 2002 | Pubmed ID: 12805965 Fibroblast Growth Factor Signaling Regulates Pillar Cell Development in the Organ of Corti The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2002 | Pubmed ID: 12417662 Knock-in Mouse Model for Resistance to Thyroid Hormone (RTH): an RTH Mutation in the Thyroid Hormone Receptor Beta Gene Disrupts Cochlear Morphogenesis Journal of the Association for Research in Otolaryngology : JARO. Sep, 2002 | Pubmed ID: 12382103 בידוד של חוט השדרה למבוגרים גרעינים עבור רצפי RNA חד-גרעין בנפט מקבילים Kaya J.E. Matson1, Anupama Sathyamurthy1, Kory R. Johnson2, Michael C. Kelly3,4, Matthew W. Kelley3, Ariel J. Levine1 1Spinal Circuits and Plasticity Unit, National Institute of Neurological Disorders and Stroke, 2Bioinformatics Section, Information Technology Program, National Institute of Neurological Disorders and Stroke, 3Laboratory of Cochlear Development, National Institute on Deafness and Other Communication Disorders, 4Single Cell Analysis Facility, Frederick National Laboratory JoVE 58413 Neuroscience תרבות של עוברי Explants שבלול העכבר וג'ין העברה על ידי Electroporation Khujista D. Haque1, Atul K. Pandey1, Matthew W. Kelley2, Chandrakala Puligilla1 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, College of Medicine, 2Laboratory of Cochlear Development, NIDCD, NIH Developmental Biology
בידוד של חוט השדרה למבוגרים גרעינים עבור רצפי RNA חד-גרעין בנפט מקבילים Kaya J.E. Matson1, Anupama Sathyamurthy1, Kory R. Johnson2, Michael C. Kelly3,4, Matthew W. Kelley3, Ariel J. Levine1 1Spinal Circuits and Plasticity Unit, National Institute of Neurological Disorders and Stroke, 2Bioinformatics Section, Information Technology Program, National Institute of Neurological Disorders and Stroke, 3Laboratory of Cochlear Development, National Institute on Deafness and Other Communication Disorders, 4Single Cell Analysis Facility, Frederick National Laboratory JoVE 58413 Neuroscience
תרבות של עוברי Explants שבלול העכבר וג'ין העברה על ידי Electroporation Khujista D. Haque1, Atul K. Pandey1, Matthew W. Kelley2, Chandrakala Puligilla1 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, College of Medicine, 2Laboratory of Cochlear Development, NIDCD, NIH Developmental Biology
