Matthew Merritt Advanced Imaging Research Center University of Texas Southwestern Medical Center Biography Publications Institution JoVE Articles Matthew Merritt has not added a biography. If you are Matthew Merritt and would like to personalize this page please email our Author Liaison for assistance. Publications A General Chemical Shift Decomposition Method for Hyperpolarized (13) C Metabolite Magnetic Resonance Imaging Magnetic Resonance in Chemistry : MRC. Apr, 2016 | Pubmed ID: 27060361 Mitochondrial Metabolism Mediates Oxidative Stress and Inflammation in Fatty Liver The Journal of Clinical Investigation. Apr, 2016 | Pubmed ID: 27035816 Multiband Spectral-spatial RF Excitation for Hyperpolarized [2-(13) C]dihydroxyacetone (13) C-MR Metabolism Studies Magnetic Resonance in Medicine. Mar, 2016 | Pubmed ID: 27017966 Metabolism of Hyperpolarized [1-(13) C]pyruvate Through Alternate Pathways in Rat Liver NMR in Biomedicine. Apr, 2016 | Pubmed ID: 26836042 Mitochondrial Metabolism Mediates Oxidative Stress and Inflammation in Fatty Liver The Journal of Clinical Investigation. Dec, 2015 | Pubmed ID: 26571396 Production of Hyperpolarized (13)CO2 from [1-(13)C]pyruvate in Perfused Liver Does Reflect Total Anaplerosis but is Not a Reliable Biomarker of Glucose Production Metabolomics : Official Journal of the Metabolomic Society. Oct, 2015 | Pubmed ID: 26543443 Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-13C]-Pyruvate Offers Improved Metabolic Imaging of Tumors Cancer Research. Nov, 2015 | Pubmed ID: 26420214 Hyperpolarized (13)C Magnetic Resonance and Its Use in Metabolic Assessment of Cultured Cells and Perfused Organs Methods in Enzymology. 2015 | Pubmed ID: 26358902 Hyperpolarized 13C NMR Detects Rapid Drug-induced Changes in Cardiac Metabolism Magnetic Resonance in Medicine. Aug, 2015 | Pubmed ID: 25168480 Development and Performance of a 129-GHz Dynamic Nuclear Polarizer in an Ultra-wide Bore Superconducting Magnet Magma (New York, N.Y.). Apr, 2015 | Pubmed ID: 25120071 Glutamine Oxidation Maintains the TCA Cycle and Cell Survival During Impaired Mitochondrial Pyruvate Transport Molecular Cell. Nov, 2014 | Pubmed ID: 25458842 Hyperpolarized Magnetic Resonance As a Sensitive Detector of Metabolic Function Biochemistry. Dec, 2014 | Pubmed ID: 25369537 Real-time Detection of Hepatic Gluconeogenic and Glycogenolytic States Using Hyperpolarized [2-13C]dihydroxyacetone The Journal of Biological Chemistry. Dec, 2014 | Pubmed ID: 25352600 Propionate Stimulates Pyruvate Oxidation in the Presence of Acetate American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2014 | Pubmed ID: 25320331 Metabolic Characteristics of Human Hearts Preserved for 12 Hours by Static Storage, Antegrade Perfusion, or Retrograde Coronary Sinus Perfusion The Journal of Thoracic and Cardiovascular Surgery. Nov, 2014 | Pubmed ID: 24642559 Simultaneous Steady-state and Dynamic 13C NMR Can Differentiate Alternative Routes of Pyruvate Metabolism in Living Cancer Cells The Journal of Biological Chemistry. Feb, 2014 | Pubmed ID: 24415759 Electron Spin Resonance Studies of Trityl OX063 at a Concentration Optimal for DNP Physical Chemistry Chemical Physics : PCCP. Jun, 2013 | Pubmed ID: 23676994 Influence of Deuteration in the Glassing Matrix on 13C Dynamic Nuclear Polarization Physical Chemistry Chemical Physics : PCCP. May, 2013 | Pubmed ID: 23552448 Dissolution DNP-NMR Spectroscopy Using Galvinoxyl As a Polarizing Agent Journal of Magnetic Resonance (San Diego, Calif. : 1997). Feb, 2013 | Pubmed ID: 23246650 The Efficiency of DPPH As a Polarising Agent for DNP-NMR Spectroscopy RSC Advances. Jan, 2012 | Pubmed ID: 23205273 Impact of Gd3+ on DNP of [1-13C]pyruvate Doped with Trityl OX063, BDPA, or 4-oxo-TEMPO The Journal of Physical Chemistry. A. May, 2012 | Pubmed ID: 22571288 Comparison of Kinetic Models for Analysis of Pyruvate-to-lactate Exchange by Hyperpolarized 13 C NMR NMR in Biomedicine. Nov, 2012 | Pubmed ID: 22451442 Nanoparticle-based PARACEST Agents: the Quenching Effect of Silica Nanoparticles on the CEST Signal from Surface-conjugated Chelates Contrast Media & Molecular Imaging. Jan-Feb, 2012 | Pubmed ID: 22344876 Production and NMR Characterization of Hyperpolarized (107,109)Ag Complexes Angewandte Chemie (International Ed. in English). Jan, 2012 | Pubmed ID: 21998014 Glucose is an Ineffective Substrate for Preservation of Machine Perfused Donor Hearts The Journal of Surgical Research. Apr, 2012 | Pubmed ID: 21816432 Flux Through Hepatic Pyruvate Carboxylase and Phosphoenolpyruvate Carboxykinase Detected by Hyperpolarized 13C Magnetic Resonance Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 22065779 Differences in Regional Myocardial Perfusion, Metabolism, MVO2, and Edema After Coronary Sinus Machine Perfusion Preservation of Canine Hearts ASAIO Journal (American Society for Artificial Internal Organs : 1992). Nov-Dec, 2011 | Pubmed ID: 22036719 Transfer of Hyperpolarization from Long T1 Storage Nuclei to Short T1 Neighbors Using FLOPSY-8 Journal of Magnetic Resonance (San Diego, Calif. : 1997). Dec, 2011 | Pubmed ID: 21974998 BDPA: an Efficient Polarizing Agent for Fast Dissolution Dynamic Nuclear Polarization NMR Spectroscopy Chemistry (Weinheim an Der Bergstrasse, Germany). Sep, 2011 | Pubmed ID: 21919088 Could 13C MRI Assist Clinical Decision-making for Patients with Heart Disease? NMR in Biomedicine. Oct, 2011 | Pubmed ID: 21608058 T2 Exchange Agents: a New Class of Paramagnetic MRI Contrast Agent That Shortens Water T2 by Chemical Exchange Rather Than Relaxation Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Dec, 2011 | Pubmed ID: 21608031 DNP by Thermal Mixing Under Optimized Conditions Yields >60,000-fold Enhancement of 89Y NMR Signal Journal of the American Chemical Society. Jun, 2011 | Pubmed ID: 21539398 1H Magic Angle Spinning Magnetic Resonance Spectroscopy for Monitoring Machine-perfused Canine Donor Heart Preservation Prior to Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jun, 2011 | Pubmed ID: 21429765 The Effect of 13C Enrichment in the Glassing Matrix on Dynamic Nuclear Polarization of [1-13C]pyruvate Physics in Medicine and Biology. Mar, 2011 | Pubmed ID: 21285486 Competition of Pyruvate with Physiological Substrates for Oxidation by the Heart: Implications for Studies with Hyperpolarized [1-13C]pyruvate American Journal of Physiology. Heart and Circulatory Physiology. May, 2010 | Pubmed ID: 20207817 Hyperpolarized 89Y Complexes As PH Sensitive NMR Probes Journal of the American Chemical Society. Feb, 2010 | Pubmed ID: 20102196 Inhibition of Carbohydrate Oxidation During the First Minute of Reperfusion After Brief Ischemia: NMR Detection of Hyperpolarized 13CO2 and H13CO3- Magnetic Resonance in Medicine. Nov, 2008 | Pubmed ID: 18956454 Alterations in Hepatic Glucose and Energy Metabolism As a Result of Calorie and Carbohydrate Restriction Hepatology (Baltimore, Md.). Nov, 2008 | Pubmed ID: 18925642 Sources of Hepatic Glucose Production by 2H2O Ingestion and Bayesian Analysis of 2H Glucuronide Enrichment Magnetic Resonance in Medicine. Sep, 2008 | Pubmed ID: 18727053 Partial Resistance to Peroxisome Proliferator-activated Receptor-alpha Agonists in ZDF Rats is Associated with Defective Hepatic Mitochondrial Metabolism Diabetes. Aug, 2008 | Pubmed ID: 18469201 Perfusion Preservation Versus Static Preservation for Cardiac Transplantation: Effects on Myocardial Function and Metabolism The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jan, 2008 | Pubmed ID: 18187093 Hyperpolarized 13C Allows a Direct Measure of Flux Through a Single Enzyme-catalyzed Step by NMR Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007 | Pubmed ID: 18056642 Dipolar Cross-relaxation Modulates Signal Amplitudes in the (1)H NMR Spectrum of Hyperpolarized [(13)C]formate Journal of Magnetic Resonance (San Diego, Calif. : 1997). Dec, 2007 | Pubmed ID: 17945520 Hyperpolarized (89)Y Offers the Potential of Direct Imaging of Metal Ions in Biological Systems by Magnetic Resonance Journal of the American Chemical Society. Oct, 2007 | Pubmed ID: 17927188 Benefits of Perfusion Preservation in Canine Hearts Stored for Short Intervals The Journal of Surgical Research. Jun, 2007 | Pubmed ID: 17509270 Hepatic UDP-glucose 13C Isotopomers from [U-13C]glucose: a Simple Analysis by 13C NMR of Urinary Menthol Glucuronide Magnetic Resonance in Medicine. Nov, 2006 | Pubmed ID: 17036288 Linkage Between Cellular Communications, Energy Utilization, and Proliferation in Metastatic Neuroendocrine Cancers Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16895983 Storage and Oxidation of Long-chain Fatty Acids in the C57/BL6 Mouse Heart As Measured by NMR Spectroscopy FEBS Letters. Jul, 2006 | Pubmed ID: 16831433 Novel 1H NMR Approach to Quantitative Tissue Oximetry Using Hexamethyldisiloxane Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Apr, 2006 | Pubmed ID: 16506157 Adiabatic JHSQC for 13C Isotopomer Analysis Magnetic Resonance in Chemistry : MRC. Apr, 2006 | Pubmed ID: 16408316 Effects of Insulin and Cytosolic Redox State on Glucose Production Pathways in the Isolated Perfused Mouse Liver Measured by Integrated 2H and 13C NMR The Biochemical Journal. Mar, 2006 | Pubmed ID: 16288601 A New Class of Macrocyclic Lanthanide Complexes for Cell Labeling and Magnetic Resonance Imaging Applications Journal of the American Chemical Society. Nov, 2005 | Pubmed ID: 16287307 Comparison of [3,4-13C2]glucose to [6,6-2H2]glucose As a Tracer for Glucose Turnover by Nuclear Magnetic Resonance Magnetic Resonance in Medicine. Jun, 2005 | Pubmed ID: 15906303 Numerical Solution of the Bloch Equations Provides Insights into the Optimum Design of PARACEST Agents for MRI Magnetic Resonance in Medicine. Apr, 2005 | Pubmed ID: 15799055 Effect of Murine Strain on Metabolic Pathways of Glucose Production After Brief or Prolonged Fasting American Journal of Physiology. Endocrinology and Metabolism. Jul, 2005 | Pubmed ID: 15797985 Differing Mechanisms of Hepatic Glucose Overproduction in Triiodothyronine-treated Rats Vs. Zucker Diabetic Fatty Rats by NMR Analysis of Plasma Glucose American Journal of Physiology. Endocrinology and Metabolism. Apr, 2005 | Pubmed ID: 15562253 Impaired Tricarboxylic Acid Cycle Activity in Mouse Livers Lacking Cytosolic Phosphoenolpyruvate Carboxykinase The Journal of Biological Chemistry. Nov, 2004 | Pubmed ID: 15347677 Glucose Production Pathways by 2H and 13C NMR in Patients with HIV-associated Lipoatrophy Magnetic Resonance in Medicine. Apr, 2004 | Pubmed ID: 15065235 Glucose Production, Gluconeogenesis, and Hepatic Tricarboxylic Acid Cycle Fluxes Measured by Nuclear Magnetic Resonance Analysis of a Single Glucose Derivative Analytical Biochemistry. Apr, 2004 | Pubmed ID: 15051530 Silencing of Phosphonate-gadolinium Magnetic Resonance Imaging Contrast by Hydroxyapatite Binding Investigative Radiology. Dec, 2003 | Pubmed ID: 14627892 PARACEST Agents: Modulating MRI Contrast Via Water Proton Exchange Accounts of Chemical Research. Oct, 2003 | Pubmed ID: 14567712 Sources of Plasma Glucose by Automated Bayesian Analysis of 2H NMR Spectra Magnetic Resonance in Medicine. Oct, 2003 | Pubmed ID: 14523948 Noninvasive Evaluation of Liver Metabolism by 2H and 13C NMR Isotopomer Analysis of Human Urine Analytical Biochemistry. Jan, 2003 | Pubmed ID: 12531210 Использование Multi-купе Dynamic один энзим Phantom для исследований гиперполяризованным магнитно-резонансных агентов Christopher M. Walker1, Matthew Merritt2, Jian-Xiong Wang2, James A. Bankson1 1Imaging Physics, University of Texas M.D. Anderson Cancer Center, 2Advanced Imaging Research Center, University of Texas Southwestern Medical Center Engineering
Использование Multi-купе Dynamic один энзим Phantom для исследований гиперполяризованным магнитно-резонансных агентов Christopher M. Walker1, Matthew Merritt2, Jian-Xiong Wang2, James A. Bankson1 1Imaging Physics, University of Texas M.D. Anderson Cancer Center, 2Advanced Imaging Research Center, University of Texas Southwestern Medical Center Engineering