Matthias Gunzer Institute for Experimental Immunology and Imaging University of Duisburg/Essen Biography Publications Institution JoVE Articles Matthias Gunzer has not added a biography. If you are Matthias Gunzer and would like to personalize this page please email our Author Liaison for assistance. Publications 3D Visualization and Quantification of Microvessels in the Whole Ischemic Mouse Brain Using Solvent-based Clearing and Light Sheet Microscopy Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jan, 2017 | Pubmed ID: 28350253 Fully Automated Evaluation of Total Glomerular Number and Capillary Tuft Size in Nephritic Kidneys Using Lightsheet Microscopy Journal of the American Society of Nephrology : JASN. Feb, 2017 | Pubmed ID: 27487796 CD11c.DTR Mice Develop a Fatal Fulminant Myocarditis After Local or Systemic Treatment with Diphtheria Toxin European Journal of Immunology. Aug, 2016 | Pubmed ID: 27184067 Alveolar Type II Epithelial Cells Contribute to the Anti-Influenza A Virus Response in the Lung by Integrating Pathogen- and Microenvironment-Derived Signals MBio. May, 2016 | Pubmed ID: 27143386 Neutrophil Migration into the Infected Uroepithelium Is Regulated by the Crosstalk Between Resident and Helper Macrophages Pathogens (Basel, Switzerland). Feb, 2016 | Pubmed ID: 26861402 Survival of Residual Neutrophils and Accelerated Myelopoiesis Limit the Efficacy of Antibody-mediated Depletion of Ly-6G+ Cells in Tumor-bearing Mice Journal of Leukocyte Biology. Jun, 2016 | Pubmed ID: 26819319 ImmunoPET/MR Imaging Allows Specific Detection of Aspergillus Fumigatus Lung Infection in Vivo Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26787852 Metastatic Status of Sentinel Lymph Nodes in Melanoma Determined Noninvasively with Multispectral Optoacoustic Imaging Science Translational Medicine. Dec, 2015 | Pubmed ID: 26659573 Role of Neutrophils in Exacerbation of Brain Injury After Focal Cerebral Ischemia in Hyperlipidemic Mice Stroke. Oct, 2015 | Pubmed ID: 26337969 Catchup: a Mouse Model for Imaging-based Tracking and Modulation of Neutrophil Granulocytes Nature Methods. May, 2015 | Pubmed ID: 25775045 Very-late-antigen-4 (VLA-4)-mediated Brain Invasion by Neutrophils Leads to Interactions with Microglia, Increased Ischemic Injury and Impaired Behavior in Experimental Stroke Acta Neuropathologica. Feb, 2015 | Pubmed ID: 25391494 Human Dendritic Cell Subsets Display Distinct Interactions with the Pathogenic Mould Aspergillus Fumigatus International Journal of Medical Microbiology : IJMM. Nov, 2014 | Pubmed ID: 25200858 Traps and Hyper Inflammation - New Ways That Neutrophils Promote or Hinder Survival British Journal of Haematology. Jan, 2014 | Pubmed ID: 24138538 Automated Characterization and Parameter-free Classification of Cell Tracks Based on Local Migration Behavior PloS One. 2013 | Pubmed ID: 24324630 Transiently Reduced PI3K/Akt Activity Drives the Development of Regulatory Function in Antigen-stimulated Naïve T-cells PloS One. 2013 | Pubmed ID: 23874604 Multimolecular Analysis of Stable Immunological Synapses Reveals Sustained Recruitment and Sequential Assembly of Signaling Clusters Molecular & Cellular Proteomics : MCP. Sep, 2013 | Pubmed ID: 23754785 Mast Cell and Macrophage Chemokines CXCL1/CXCL2 Control the Early Stage of Neutrophil Recruitment During Tissue Inflammation Blood. Jun, 2013 | Pubmed ID: 23645836 A Role for LFA-1 in Delaying T-lymphocyte Egress from Lymph Nodes The EMBO Journal. Mar, 2013 | Pubmed ID: 23443048 T Cell Activation Results in Conformational Changes in the Src Family Kinase Lck to Induce Its Activation Science Signaling. Feb, 2013 | Pubmed ID: 23423439 Cellular Immune Reactions in the Lung Immunological Reviews. Jan, 2013 | Pubmed ID: 23278750 White-opaque Switching of Candida Albicans Allows Immune Evasion in an Environment-dependent Fashion Eukaryotic Cell. Jan, 2013 | Pubmed ID: 23125350 Pilus Adhesin RrgA Interacts with Complement Receptor 3, Thereby Affecting Macrophage Function and Systemic Pneumococcal Disease MBio. Dec, 2012 | Pubmed ID: 23269830 TLR7 Contributes to the Rapid Progression but Not to the Overall Fatal Outcome of Secondary Pneumococcal Disease Following Influenza A Virus Infection Journal of Innate Immunity. Nov, 2012 | Pubmed ID: 23154432 Cdc42 Activity Regulates Hematopoietic Stem Cell Aging and Rejuvenation Cell Stem Cell. May, 2012 | Pubmed ID: 22560076 Connexin-43 in the Osteogenic BM Niche Regulates Its Cellular Composition and the Bidirectional Traffic of Hematopoietic Stem Cells and Progenitors Blood. Apr, 2012 | Pubmed ID: 22498741 Vaccine Adjuvants: Tailor-made Mast-cell Granules Nature Materials. Feb, 2012 | Pubmed ID: 22349854 Surface Display of Gaussia Princeps Luciferase Allows Sensitive Fungal Pathogen Detection During Cutaneous Aspergillosis Virulence. Jan, 2012 | Pubmed ID: 22286700 Human Regulatory T Cells Rapidly Suppress T Cell Receptor-induced Ca(2+), NF-κB, and NFAT Signaling in Conventional T Cells Science Signaling. Dec, 2011 | Pubmed ID: 22375050 Mast Cells Are Key Promoters of Contact Allergy That Mediate the Adjuvant Effects of Haptens Immunity. Jun, 2011 | Pubmed ID: 21703544 Imaging Hematopoietic Stem Cells in the Marrow of Long Bones in Vivo Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21618094 Phagocyte Responses Towards Aspergillus Fumigatus International Journal of Medical Microbiology : IJMM. Jun, 2011 | Pubmed ID: 21571589 Shaping the Fungal Adaptome--stress Responses of Aspergillus Fumigatus International Journal of Medical Microbiology : IJMM. Jun, 2011 | Pubmed ID: 21565548 On the Way Toward Systems Biology of Aspergillus Fumigatus Infection International Journal of Medical Microbiology : IJMM. Jun, 2011 | Pubmed ID: 21555243 Sphingosine 1-phosphate-induced Motility and Endocytosis of Dendritic Cells is Regulated by SWAP-70 Through RhoA Journal of Immunology (Baltimore, Md. : 1950). May, 2011 | Pubmed ID: 21421853 Rapid Immunomagnetic Negative Enrichment of Neutrophil Granulocytes from Murine Bone Marrow for Functional Studies in Vitro and in Vivo PloS One. 2011 | Pubmed ID: 21383835 G-CSF-mediated Thrombopoietin Release Triggers Neutrophil Motility and Mobilization from Bone Marrow Via Induction of Cxcr2 Ligands Blood. Apr, 2011 | Pubmed ID: 21224471 Pharmacological Inhibition of EGFR Signaling Enhances G-CSF-induced Hematopoietic Stem Cell Mobilization Nature Medicine. Oct, 2010 | Pubmed ID: 20871610 Toll-like Receptor 4 Signaling by Follicular Dendritic Cells is Pivotal for Germinal Center Onset and Affinity Maturation Immunity. Jul, 2010 | Pubmed ID: 20643339 Production of Extracellular Traps Against Aspergillus Fumigatus in Vitro and in Infected Lung Tissue is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA PLoS Pathogens. Apr, 2010 | Pubmed ID: 20442864 APC, T Cells, and the Immune Synapse Current Topics in Microbiology and Immunology. 2010 | Pubmed ID: 19960317 Imaging Immunity European Journal of Immunology. Dec, 2009 | Pubmed ID: 19953588 Immune Synapse Formation Determines Interaction Forces Between T Cells and Antigen-presenting Cells Measured by Atomic Force Microscopy Proceedings of the National Academy of Sciences of the United States of America. Oct, 2009 | Pubmed ID: 19822763 Src Homology 2-domain Containing Leukocyte-specific Phosphoprotein of 76 KDa is Mandatory for TCR-mediated Inside-out Signaling, but Dispensable for CXCR4-mediated LFA-1 Activation, Adhesion, and Migration of T Cells Journal of Immunology (Baltimore, Md. : 1950). Nov, 2009 | Pubmed ID: 19812192 Identification of a Putative Crf Splice Variant and Generation of Recombinant Antibodies for the Specific Detection of Aspergillus Fumigatus PloS One. 2009 | Pubmed ID: 19675673 Retrospective: Birth of the Cool - Imaging and Microbiology from Ibn Al-Haytham to Jean Comandon Biotechnology Journal. Jun, 2009 | Pubmed ID: 19548233 Guanine Nucleotide-binding Proteins of the G12 Family Shape Immune Functions by Controlling CD4+ T Cell Adhesiveness and Motility Immunity. May, 2009 | Pubmed ID: 19409815 Human Chorionic Gonadotropin Attracts Regulatory T Cells into the Fetal-maternal Interface During Early Human Pregnancy Journal of Immunology (Baltimore, Md. : 1950). May, 2009 | Pubmed ID: 19380797 Altered Cellular Dynamics and Endosteal Location of Aged Early Hematopoietic Progenitor Cells Revealed by Time-lapse Intravital Imaging in Long Bones Blood. Jul, 2009 | Pubmed ID: 19357397 Increased Susceptibility for Superinfection with Streptococcus Pneumoniae During Influenza Virus Infection is Not Caused by TLR7-mediated Lymphopenia PloS One. 2009 | Pubmed ID: 19290047 Deriving a Germinal Center Lymphocyte Migration Model from Two-photon Data The Journal of Experimental Medicine. Dec, 2008 | Pubmed ID: 19047437 3D and 4D Imaging of Immune Cells in Vitro and in Vivo Histochemistry and Cell Biology. Dec, 2008 | Pubmed ID: 18855003 Microglia Cells Protect Neurons by Direct Engulfment of Invading Neutrophil Granulocytes: a New Mechanism of CNS Immune Privilege The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2008 | Pubmed ID: 18524901 Signaling Signatures and Functional Properties of Anti-human CD28 Superagonistic Antibodies PloS One. 2008 | Pubmed ID: 18320029 Intravital Two-photon Microscopy: Focus on Speed and Time Resolved Imaging Modalities Immunological Reviews. Feb, 2008 | Pubmed ID: 18275472 Basal Expression of the Aspergillus Fumigatus Transcriptional Activator CpcA is Sufficient to Support Pulmonary Aspergillosis Fungal Genetics and Biology : FG & B. May, 2008 | Pubmed ID: 18249572 Analyzing the Physicodynamics of Immune Cells in a Three-dimensional Collagen Matrix Methods in Molecular Biology (Clifton, N.J.). 2007 | Pubmed ID: 17876098 The Molecular Makeup and Function of Regulatory and Effector Synapses Immunological Reviews. Aug, 2007 | Pubmed ID: 17624952 The Power of Single and Multibeam Two-photon Microscopy for High-resolution and High-speed Deep Tissue and Intravital Imaging Biophysical Journal. Oct, 2007 | Pubmed ID: 17557785 Vitamin D Receptor Signaling Contributes to Susceptibility to Infection with Leishmania Major FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2007 | Pubmed ID: 17551101 Stem Cells, Aging, Niche, Adhesion and Cdc42: a Model for Changes in Cell-cell Interactions and Hematopoietic Stem Cell Aging Cell Cycle (Georgetown, Tex.). Apr, 2007 | Pubmed ID: 17404508 Naive B Cells Generate Regulatory T Cells in the Presence of a Mature Immunologic Synapse Blood. Sep, 2007 | Pubmed ID: 17392507 Environmental Dimensionality Controls the Interaction of Phagocytes with the Pathogenic Fungi Aspergillus Fumigatus and Candida Albicans PLoS Pathogens. Feb, 2007 | Pubmed ID: 17274685 Imaging the Immunological Synapse European Journal of Immunology. Feb, 2007 | Pubmed ID: 17273995 The Biophysics of T Lymphocyte Activation in Vitro and in Vivo Results and Problems in Cell Differentiation. 2006 | Pubmed ID: 17068973 Immune Response Modifiers--mode of Action Experimental Dermatology. May, 2006 | Pubmed ID: 16630072 Microglia Provide Neuroprotection After Ischemia FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2006 | Pubmed ID: 16473887 Tuning Immune Responses: Diversity and Adaptation of the Immunological Synapse Nature Reviews. Immunology. Jul, 2005 | Pubmed ID: 15999094 Systemic Administration of a TLR7 Ligand Leads to Transient Immune Incompetence Due to Peripheral-blood Leukocyte Depletion Blood. Oct, 2005 | Pubmed ID: 15976181 The Mycoplasma-derived Macrophage-activating 2-kilodalton Lipopeptide Triggers Global Immune Activation on Nasal Mucosa-associated Lymphoid Tissues Infection and Immunity. Dec, 2004 | Pubmed ID: 15557620 A Spectrum of Biophysical Interaction Modes Between T Cells and Different Antigen-presenting Cells During Priming in 3-D Collagen and in Vivo Blood. Nov, 2004 | Pubmed ID: 15256430 Molecular and Functional Analysis of Shiga Toxin-induced Response Patterns in Human Vascular Endothelial Cells Blood. Aug, 2003 | Pubmed ID: 12702508 Loss of S100A9 (MRP14) Results in Reduced Interleukin-8-induced CD11b Surface Expression, a Polarized Microfilament System, and Diminished Responsiveness to Chemoattractants in Vitro Molecular and Cellular Biology. Feb, 2003 | Pubmed ID: 12529407 Localization of Mu-opioid Receptor 1A on Sensory Nerve Fibers in Human Skin Regulatory Peptides. Dec, 2002 | Pubmed ID: 12468112 DC-T-cell Synapses Trends in Immunology. Feb, 2002 | Pubmed ID: 11956008 लाइट शीट माइक्रोस्कोपी द्वारा फुलमिंटेंट माईकार्डाइटिस के मरीन मॉडल में ल्यूकोसाइट फैलाने का मात्रात्मक विज़ुअलाइज़ेशन Linda Männ1, Anika Klingberg2, Matthias Gunzer2, Mike Hasenberg3 1Department of Translational Skin Cancer Research, University of Duisburg/Essen, 2Institute for Experimental Immunology and Imaging, University of Duisburg/Essen, 3Imaging Center Essen, Electron Microscopy Unit, University Hospital of Essen JoVE 55450 Medicine 2-photon माइक्रोस्कोपी का उपयोग संक्रमित फेफड़े में neutrophils द्वारा phagocytosis और NET गठन के प्रत्यक्ष अवलोकन Mike Hasenberg1, Anja Köhler1, Susanne Bonifatius1, Andreas Jeron2, Matthias Gunzer1 1Institute for Molecular and Clinical Immunology, Otto-von-Guericke University Magdeburg, 2Department of Immunoregulation, Helmholtz Center for Infection Research JoVE 2659 Immunology and Infection
लाइट शीट माइक्रोस्कोपी द्वारा फुलमिंटेंट माईकार्डाइटिस के मरीन मॉडल में ल्यूकोसाइट फैलाने का मात्रात्मक विज़ुअलाइज़ेशन Linda Männ1, Anika Klingberg2, Matthias Gunzer2, Mike Hasenberg3 1Department of Translational Skin Cancer Research, University of Duisburg/Essen, 2Institute for Experimental Immunology and Imaging, University of Duisburg/Essen, 3Imaging Center Essen, Electron Microscopy Unit, University Hospital of Essen JoVE 55450 Medicine
2-photon माइक्रोस्कोपी का उपयोग संक्रमित फेफड़े में neutrophils द्वारा phagocytosis और NET गठन के प्रत्यक्ष अवलोकन Mike Hasenberg1, Anja Köhler1, Susanne Bonifatius1, Andreas Jeron2, Matthias Gunzer1 1Institute for Molecular and Clinical Immunology, Otto-von-Guericke University Magdeburg, 2Department of Immunoregulation, Helmholtz Center for Infection Research JoVE 2659 Immunology and Infection
