Michael L. Dustin Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences The University of Oxford Biography Publications Institution JoVE Articles Michael L. Dustin has not added a biography. If you are Michael L. Dustin and would like to personalize this page please email our Author Liaison for assistance. Publications Magnesium for T Cells: Strong to the Finish! Trends in Immunology. Apr, 2022 | Pubmed ID: 35260350 Dephosphorylation Accelerates the Dissociation of ZAP70 from the T Cell Receptor Proceedings of the National Academy of Sciences of the United States of America. 03, 2022 | Pubmed ID: 35197288 The Interplay Between Membrane Topology and Mechanical Forces in Regulating T Cell Receptor Activity Communications Biology. 01, 2022 | Pubmed ID: 35017678 Locked and Loaded: Strong TCR Signaling Primes Anti-PD-1 Therapy Trends in Immunology. Dec, 2021 | Pubmed ID: 34772621 Author Correction: A Dynamic CD2-rich Compartment at the Outer Edge of the Immunological Synapse Boosts and Integrates Signals Nature Immunology. Jan, 2021 | Pubmed ID: 33122852 A Dynamic CD2-rich Compartment at the Outer Edge of the Immunological Synapse Boosts and Integrates Signals Nature Immunology. 10, 2020 | Pubmed ID: 32929275 Supramolecular Attack Particles Are Autonomous Killing Entities Released from Cytotoxic T Cells Science (New York, N.Y.). 05, 2020 | Pubmed ID: 32381591 A Checkpoint Cliffhanger at the Dawn of Placental Mammals The Journal of Biological Chemistry. 04, 2020 | Pubmed ID: 32245902 Author Correction: Human in Vitro-induced Regulatory T Cells Display Dlgh1 Dependent and PKC-θ Restrained Suppressive Activity Scientific Reports. Feb, 2020 | Pubmed ID: 32076101 Cutting Edge: Synapse Propensity of Human Memory CD8 T Cells Confers Competitive Advantage over Naive Counterparts Journal of Immunology (Baltimore, Md. : 1950). 08, 2019 | Pubmed ID: 31201237 An X-ray Vision for Phosphoantigen Recognition Immunity. 04, 2019 | Pubmed ID: 30995494 Integrins and Their Role in Immune Cell Adhesion Cell. 04, 2019 | Pubmed ID: 30952447 CD45 Exclusion- and Cross-linking-based Receptor Signaling Together Broaden FcεRI Reactivity Science Signaling. 12, 2018 | Pubmed ID: 30563863 CD8 Helps TCR Catch Slippery Self PMHC Nature Immunology. 12, 2018 | Pubmed ID: 30420625 Tumor Necrosis Factor Receptor Superfamily in T Cell Priming and Effector Function Advances in Immunology. 2018 | Pubmed ID: 30366518 Natural Killers Shed Attachments to Kill Again The Journal of Cell Biology. 09, 2018 | Pubmed ID: 30108125 Distinct Behavior of Myelomonocytic Cells and CD8 T Cells Underlies the Hepatic Response to Wellcome Open Research. 2018 | Pubmed ID: 29862325 Full Control of Ligand Positioning Reveals Spatial Thresholds for T Cell Receptor Triggering Nature Nanotechnology. 07, 2018 | Pubmed ID: 29713075 A Stretch of Negatively Charged Amino Acids of Linker for Activation of T-Cell Adaptor Has a Dual Role in T-Cell Antigen Receptor Intracellular Signaling Frontiers in Immunology. 2018 | Pubmed ID: 29456532 Durable Interactions of T Cells with T Cell Receptor Stimuli in the Absence of a Stable Immunological Synapse Cell Reports. 01, 2018 | Pubmed ID: 29320731 Crosstalk Between Regulatory T Cells and Tumor-Associated Dendritic Cells Negates Anti-tumor Immunity in Pancreatic Cancer Cell Reports. 07, 2017 | Pubmed ID: 28723561 Human in Vitro-induced Regulatory T Cells Display Dlgh1dependent and PKC-θ Restrained Suppressive Activity Scientific Reports. 06, 2017 | Pubmed ID: 28652577 Comprehensive Analysis of Immunological Synapse Phenotypes Using Supported Lipid Bilayers Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 28255717 Spatial Control of Biological Ligands on Surfaces Applied to T Cell Activation Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 28255709 The Immune Synapse: Past, Present, and Future Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 28255692 Help to Go: T Cells Transfer CD40L to Antigen-presenting B Cells European Journal of Immunology. 01, 2017 | Pubmed ID: 28004382 Complement Receptors in Myeloid Cell Adhesion and Phagocytosis Microbiology Spectrum. 11, 2016 | Pubmed ID: 27809953 HIV Envelope Gp120 Alters T Cell Receptor Mobilization in the Immunological Synapse of Uninfected CD4 T Cells and Augments T Cell Activation Journal of Virology. Dec, 2016 | Pubmed ID: 27630246 Force Bistability in Adhesion Switch Biophysical Journal. 09, 2016 | Pubmed ID: 27602717 Programmed Death Ligand-1 Expression on Donor T Cells Drives Graft-versus-host Disease Lethality The Journal of Clinical Investigation. Jul, 2016 | Pubmed ID: 27294527 Tapping out a Mechanical Code for T Cell Triggering The Journal of Cell Biology. 06, 2016 | Pubmed ID: 27269063 CELL SIGNALING. Liquidity in Immune Cell Signaling Science (New York, N.Y.). Apr, 2016 | Pubmed ID: 27126023 High-Throughput Mechanobiology Screening Platform Using Micro- and Nanotopography Nano Letters. Apr, 2016 | Pubmed ID: 26990380 Phagocytes Get Close to Their Enemies Developmental Cell. Jan, 2016 | Pubmed ID: 26812012 Agile CD22 Nanoclusters Run Rings Around Fenced BCR The EMBO Journal. Feb, 2016 | Pubmed ID: 26746852 Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria PLoS Pathogens. 2015 | Pubmed ID: 26562533 T Cells Have a Light Touch Biophysical Journal. May, 2015 | Pubmed ID: 25954864 Force and Affinity in Ligand Discrimination by the TCR Trends in Immunology. 12, 2014 | Pubmed ID: 25466309 The Immunological Synapse Cancer Immunology Research. Nov, 2014 | Pubmed ID: 25367977 CD28-CD80 Interactions Control Regulatory T Cell Motility and Immunological Synapse Formation Journal of Immunology (Baltimore, Md. : 1950). Dec, 2014 | Pubmed ID: 25355918 What Counts in the Immunological Synapse? Molecular Cell. Apr, 2014 | Pubmed ID: 24766889 How T Cells Lose Their Touch Immunity. Feb, 2014 | Pubmed ID: 24560192 Polarized Release of T-cell-receptor-enriched Microvesicles at the Immunological Synapse Nature. Mar, 2014 | Pubmed ID: 24487619 TCR Signaling: the Barrier Within Nature Immunology. Feb, 2014 | Pubmed ID: 24448571 Cross Talk Between CD3 and CD28 is Spatially Modulated by Protein Lateral Mobility Molecular and Cellular Biology. Mar, 2014 | Pubmed ID: 24379441 PD-1 Promotes Immune Exhaustion by Inducing Antiviral T Cell Motility Paralysis The Journal of Experimental Medicine. Apr, 2013 | Pubmed ID: 23530125 Mechanosensing in T Lymphocyte Activation Biophysical Journal. Jan, 2012 | Pubmed ID: 22339876 Self-reactive Human CD4 T Cell Clones Form Unusual Immunological Synapses The Journal of Experimental Medicine. Feb, 2012 | Pubmed ID: 22312112 Scaffold Protein Disc Large Homolog 1 is Required for T-cell Receptor-induced Activation of Regulatory T-cell Function Proceedings of the National Academy of Sciences of the United States of America. Jan, 2012 | Pubmed ID: 22307621 Immunology. Antigen Feast or Famine Science (New York, N.Y.). Jan, 2012 | Pubmed ID: 22282794 Distinct Influences of Peptide-MHC Quality and Quantity on in Vivo T-cell Responses Proceedings of the National Academy of Sciences of the United States of America. Jan, 2012 | Pubmed ID: 22223661 Visualization of Cell-Cell Interaction Contacts: Synapses and Kinapses Self/nonself. 4, 2011 | Pubmed ID: 22299060 Integrin Inside-out Signaling and the Immunological Synapse Current Opinion in Cell Biology. Nov, 2011 | Pubmed ID: 22129583 PKC-θ: Hitting the Bull's Eye Nature Immunology. Nov, 2011 | Pubmed ID: 22012436 New Insights into the T Cell Synapse from Single Molecule Techniques Nature Reviews. Immunology. Oct, 2011 | Pubmed ID: 21904389 HIV Envelope Gp120 Activates LFA-1 on CD4 T-lymphocytes and Increases Cell Susceptibility to LFA-1-targeting Leukotoxin (LtxA) PloS One. 2011 | Pubmed ID: 21850260 Boltzmann Energy-based Image Analysis Demonstrates That Extracellular Domain Size Differences Explain Protein Segregation at Immune Synapses PLoS Computational Biology. Aug, 2011 | Pubmed ID: 21829338 Flt3L Controls the Development of Radiosensitive Dendritic Cells in the Meninges and Choroid Plexus of the Steady-state Mouse Brain The Journal of Experimental Medicine. Aug, 2011 | Pubmed ID: 21788405 PKC-θ Function at the Immunological Synapse: Prospects for Therapeutic Targeting Trends in Immunology. Aug, 2011 | Pubmed ID: 21733754 The Critical Role of Agrin in the Hematopoietic Stem Cell Niche Blood. Sep, 2011 | Pubmed ID: 21653324 A Biophysical Model of Cell Adhesion Mediated by Immunoadhesin Drugs and Antibodies PloS One. 2011 | Pubmed ID: 21629715 T-cell Triggering Thresholds Are Modulated by the Number of Antigen Within Individual T-cell Receptor Clusters Proceedings of the National Academy of Sciences of the United States of America. May, 2011 | Pubmed ID: 21576490 A Dynamic T Cell-limited Checkpoint Regulates Affinity-dependent B Cell Entry into the Germinal Center The Journal of Experimental Medicine. Jun, 2011 | Pubmed ID: 21576382 A Human Intercellular Adhesion Molecule (ICAM-1) Distinct from LFA-1. J. Immunol. 1986. 137: 1270-1274 Journal of Immunology (Baltimore, Md. : 1950). May, 2011 | Pubmed ID: 21505215 Induction by IL 1 and Interferon-γ: Tissue Distribution, Biochemistry, and Function of a Natural Adherence Molecule (ICAM-1). J. Immunol. 1986. 137: 245-254 Journal of Immunology (Baltimore, Md. : 1950). May, 2011 | Pubmed ID: 21505214 Migration of Cytotoxic Lymphocytes in Cell Cycle Permits Local MHC I-dependent Control of Division at Sites of Viral Infection The Journal of Experimental Medicine. Apr, 2011 | Pubmed ID: 21464219 Dynamic Imaging of the Effector Immune Response to Listeria Infection in Vivo PLoS Pathogens. Mar, 2011 | Pubmed ID: 21455492 The Growth Factor Progranulin Binds to TNF Receptors and is Therapeutic Against Inflammatory Arthritis in Mice Science (New York, N.Y.). Apr, 2011 | Pubmed ID: 21393509 CTLs Respond with Activation and Granule Secretion when Serving As Targets for T-cell Recognition Blood. Jan, 2011 | Pubmed ID: 21045195 Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter Cell. Nov, 2010 | Pubmed ID: 21074050 Signaling Microdomains in T Cells FEBS Letters. Dec, 2010 | Pubmed ID: 20965175 HIV-1 Virological Synapse is Not Simply a Copycat of the Immunological Synapse Viruses. May, 2010 | Pubmed ID: 20890395 Understanding the Structure and Function of the Immunological Synapse Cold Spring Harbor Perspectives in Biology. Oct, 2010 | Pubmed ID: 20843980 Development and Migration of Plasma Cells in the Mouse Lymph Node Immunity. Jul, 2010 | Pubmed ID: 20619695 High Plasma Membrane Lipid Order Imaged at the Immunological Synapse Periphery in Live T Cells Molecular Membrane Biology. Aug, 2010 | Pubmed ID: 20540668 Cytotoxic Immunological Synapses Immunological Reviews. May, 2010 | Pubmed ID: 20536553 Affinity Measured by Microcluster The Journal of Experimental Medicine. May, 2010 | Pubmed ID: 20439542 Monocyte Trafficking to Hepatic Sites of Bacterial Infection is Chemokine Independent and Directed by Focal Intercellular Adhesion Molecule-1 Expression Journal of Immunology (Baltimore, Md. : 1950). Jun, 2010 | Pubmed ID: 20435926 Essential Role of Ubiquitin and TSG101 Protein in Formation and Function of the Central Supramolecular Activation Cluster Immunity. Apr, 2010 | Pubmed ID: 20399684 Protein Kinase C-theta Mediates Negative Feedback on Regulatory T Cell Function Science (New York, N.Y.). Apr, 2010 | Pubmed ID: 20339032 Functional Anatomy of T Cell Activation and Synapse Formation Annual Review of Immunology. Mar, 2010 | Pubmed ID: 19968559 Insights into Function of the Immunological Synapse from Studies with Supported Planar Bilayers Current Topics in Microbiology and Immunology. 2010 | Pubmed ID: 19960306 Two-photon Laser Scanning Microscopy Imaging of Intact Spinal Cord and Cerebral Cortex Reveals Requirement for CXCR6 and Neuroinflammation in Immune Cell Infiltration of Cortical Injury Sites Journal of Immunological Methods. Jan, 2010 | Pubmed ID: 19800886 Nanoengineering of Immune Cell Function Materials Research Society Symposia Proceedings. Materials Research Society. Jan, 2009 | Pubmed ID: 21562611 Modular Design of Immunological Synapses and Kinapses Cold Spring Harbor Perspectives in Biology. Jul, 2009 | Pubmed ID: 20066081 Kinetics of Early T Cell Receptor Signaling Regulate the Pathway of Lytic Granule Delivery to the Secretory Domain Immunity. Oct, 2009 | Pubmed ID: 19833088 Human Immunodeficiency Virus Type 1 Envelope Gp120-induced Partial T-cell Receptor Signaling Creates an F-actin-depleted Zone in the Virological Synapse Journal of Virology. Nov, 2009 | Pubmed ID: 19710135 Galectin-3 Negatively Regulates TCR-mediated CD4+ T-cell Activation at the Immunological Synapse Proceedings of the National Academy of Sciences of the United States of America. Aug, 2009 | Pubmed ID: 19706535 Feedback Control of Regulatory T Cell Homeostasis by Dendritic Cells in Vivo The Journal of Experimental Medicine. Aug, 2009 | Pubmed ID: 19667061 Integrin-dependent Organization and Bidirectional Vesicular Traffic at Cytotoxic Immune Synapses Immunity. Jul, 2009 | Pubmed ID: 19592272 The Class II Phosphatidylinositol 3 Kinase C2beta is Required for the Activation of the K+ Channel KCa3.1 and CD4 T-cells Molecular Biology of the Cell. Sep, 2009 | Pubmed ID: 19587117 CCR7 Signalling As an Essential Regulator of CNS Infiltration in T-cell Leukaemia Nature. Jun, 2009 | Pubmed ID: 19536265 Multiscale Analysis of T Cell Activation: Correlating in Vitro and in Vivo Analysis of the Immunological Synapse Current Topics in Microbiology and Immunology. 2009 | Pubmed ID: 19521681 Supported Bilayers at the Vanguard of Immune Cell Activation Studies Journal of Structural Biology. Oct, 2009 | Pubmed ID: 19500675 The Coreceptor CD2 Uses Plasma Membrane Microdomains to Transduce Signals in T Cells The Journal of Cell Biology. May, 2009 | Pubmed ID: 19398758 The Cellular Context of T Cell Signaling Immunity. Apr, 2009 | Pubmed ID: 19371714 Visualizing Immune System Complexity Science Signaling. 2009 | Pubmed ID: 19366990 T Cell Antigen Receptor Signaling and Immunological Synapse Stability Require Myosin IIA Nature Immunology. May, 2009 | Pubmed ID: 19349987 Phospholipase D1 Regulates Lymphocyte Adhesion Via Upregulation of Rap1 at the Plasma Membrane Molecular and Cellular Biology. Jun, 2009 | Pubmed ID: 19332557 Renal Dendritic Cells: an Update Nephron. Experimental Nephrology. 2009 | Pubmed ID: 19276627 Myelomonocytic Cell Recruitment Causes Fatal CNS Vascular Injury During Acute Viral Meningitis Nature. Jan, 2009 | Pubmed ID: 19011611 Visualization of Cell-cell Interaction Contacts-synapses and Kinapses Advances in Experimental Medicine and Biology. 2008 | Pubmed ID: 19065791 Spatiotemporal Regulation of T Cell Costimulation by TCR-CD28 Microclusters and Protein Kinase C Theta Translocation Immunity. Oct, 2008 | Pubmed ID: 18848472 Lrp4 is a Receptor for Agrin and Forms a Complex with MuSK Cell. Oct, 2008 | Pubmed ID: 18848351 Nanoscale Increases in CD2-CD48-mediated Intermembrane Spacing Decrease Adhesion and Reorganize the Immunological Synapse The Journal of Biological Chemistry. Dec, 2008 | Pubmed ID: 18826951 T Cell-dendritic Cell Immunological Synapses Contain TCR-dependent CD28-CD80 Clusters That Recruit Protein Kinase C Theta Journal of Immunology (Baltimore, Md. : 1950). Oct, 2008 | Pubmed ID: 18802089 Protein Kinase C Theta Regulates Stability of the Peripheral Adhesion Ring Junction and Contributes to the Sensitivity of Target Cell Lysis by CTL Journal of Immunology (Baltimore, Md. : 1950). Oct, 2008 | Pubmed ID: 18802085 Radiation-induced CXCL16 Release by Breast Cancer Cells Attracts Effector T Cells Journal of Immunology (Baltimore, Md. : 1950). Sep, 2008 | Pubmed ID: 18713980 Modulation of T Cell Activation by Stomatin-like Protein 2 Journal of Immunology (Baltimore, Md. : 1950). Aug, 2008 | Pubmed ID: 18641330 Human Immunodeficiency Virus Type 1 Envelope Gp120 Induces a Stop Signal and Virological Synapse Formation in Noninfected CD4+ T Cells Journal of Virology. Oct, 2008 | Pubmed ID: 18632854 Hunter to Gatherer and Back: Immunological Synapses and Kinapses As Variations on the Theme of Amoeboid Locomotion Annual Review of Cell and Developmental Biology. 2008 | Pubmed ID: 18598213 Th1 and Th2 Cells Form Morphologically Distinct Immunological Synapses Journal of Immunology (Baltimore, Md. : 1950). Jul, 2008 | Pubmed ID: 18566405 Micropatterning of Costimulatory Ligands Enhances CD4+ T Cell Function Proceedings of the National Academy of Sciences of the United States of America. Jun, 2008 | Pubmed ID: 18505845 A Coupled Diffusion-kinetics Model for Analysis of Contact-area FRAP Experiment Biophysical Journal. Jul, 2008 | Pubmed ID: 18390628 Measuring Diffusion and Binding Kinetics by Contact Area FRAP Biophysical Journal. Jul, 2008 | Pubmed ID: 18390627 Synaptic Asymmetry to Go Cell. Mar, 2008 | Pubmed ID: 18329360 T-cell Activation Through Immunological Synapses and Kinapses Immunological Reviews. Feb, 2008 | Pubmed ID: 18275476 Cutting Edge: Activation by Innate Cytokines or Microbial Antigens Can Cause Arrest of Natural Killer T Cell Patrolling of Liver Sinusoids Journal of Immunology (Baltimore, Md. : 1950). Feb, 2008 | Pubmed ID: 18250405 T Cell Receptor Microcluster Transport Through Molecular Mazes Reveals Mechanism of Translocation Biophysical Journal. Apr, 2008 | Pubmed ID: 18199675 Tug of War at the Exit Door Immunity. Jan, 2008 | Pubmed ID: 18199414 Supported Planar Bilayers for Study of the Immunological Synapse Current Protocols in Immunology / Edited by John E. Coligan ... [et Al.]. Feb, 2007 | Pubmed ID: 18432988 Mechanisms for Segregating T Cell Receptor and Adhesion Molecules During Immunological Synapse Formation in Jurkat T Cells Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007 | Pubmed ID: 18077330 Dynamics of Host Defense: the View at the Front Lines Nature Immunology. Nov, 2007 | Pubmed ID: 17952039 Cell Adhesion Molecules and Actin Cytoskeleton at Immune Synapses and Kinapses Current Opinion in Cell Biology. Oct, 2007 | Pubmed ID: 17923403 Quantification and Modeling of Tripartite CD2-, CD58FC Chimera (alefacept)-, and CD16-mediated Cell Adhesion The Journal of Biological Chemistry. Nov, 2007 | Pubmed ID: 17911103 Peptide-MHC Potency Governs Dynamic Interactions Between T Cells and Dendritic Cells in Lymph Nodes Nature Immunology. Aug, 2007 | Pubmed ID: 17632517 Small GTPases and LFA-1 Reciprocally Modulate Adhesion and Signaling Immunological Reviews. Aug, 2007 | Pubmed ID: 17624948 Requirements for T Lymphocyte Migration in Explanted Lymph Nodes Journal of Immunology (Baltimore, Md. : 1950). Jun, 2007 | Pubmed ID: 17548612 Opposing Effects of PKCtheta and WASp on Symmetry Breaking and Relocation of the Immunological Synapse Cell. May, 2007 | Pubmed ID: 17512410 The Lymphocyte Function-associated Antigen-1 Receptor Costimulates Plasma Membrane Ras Via Phospholipase D2 Nature Cell Biology. Jun, 2007 | Pubmed ID: 17486117 In Vivo Imaging of Germinal Centres Reveals a Dynamic Open Structure Nature. Mar, 2007 | Pubmed ID: 17268470 Force As a Facilitator of Integrin Conformational Changes During Leukocyte Arrest on Blood Vessels and Antigen-presenting Cells Immunity. Jan, 2007 | Pubmed ID: 17241958 Analysis of Two-dimensional Dissociation Constant of Laterally Mobile Cell Adhesion Molecules Biophysical Journal. Feb, 2007 | Pubmed ID: 17085486 Mechanisms of Cellular Avidity Regulation in CD2-CD58-Mediated T Cell Adhesion ACS Chemical Biology. Nov, 2006 | Pubmed ID: 17168569 Control of Antigen Presentation with a Photoreleasable Agonist Peptide Journal of the American Chemical Society. Dec, 2006 | Pubmed ID: 17131984 Quantum Dot/peptide-MHC Biosensors Reveal Strong CD8-dependent Cooperation Between Self and Viral Antigens That Augment the T Cell Response Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17077145 Impact of the Immunological Synapse on T Cell Signaling Results and Problems in Cell Differentiation. 2006 | Pubmed ID: 17068972 Innate Response to Focal Necrotic Injury Inside the Blood-brain Barrier Journal of Immunology (Baltimore, Md. : 1950). Oct, 2006 | Pubmed ID: 17015712 Lateral Membrane Waves Constitute a Universal Dynamic Pattern of Motile Cells Physical Review Letters. Jul, 2006 | Pubmed ID: 16907546 Immunology. When F-actin Becomes Too Much of a Good Thing Science (New York, N.Y.). Aug, 2006 | Pubmed ID: 16902113 T Cell Receptor-proximal Signals Are Sustained in Peripheral Microclusters and Terminated in the Central Supramolecular Activation Cluster Immunity. Jul, 2006 | Pubmed ID: 16860761 Dynamic Imaging of the Immune System: Progress, Pitfalls and Promise Nature Reviews. Immunology. Jul, 2006 | Pubmed ID: 16799470 T Cell-dendritic Cell Immunological Synapses Current Opinion in Immunology. Aug, 2006 | Pubmed ID: 16777399 T Cells Like a Firm Molecular Handshake Proceedings of the National Academy of Sciences of the United States of America. Mar, 2006 | Pubmed ID: 16537367 Regulatory T Cells Inhibit Stable Contacts Between CD4+ T Cells and Dendritic Cells in Vivo The Journal of Experimental Medicine. Mar, 2006 | Pubmed ID: 16533880 CD80 Cytoplasmic Domain Controls Localization of CD28, CTLA-4, and Protein Kinase Ctheta in the Immunological Synapse Journal of Immunology (Baltimore, Md. : 1950). Dec, 2005 | Pubmed ID: 16339518 Altered TCR Signaling from Geometrically Repatterned Immunological Synapses Science (New York, N.Y.). Nov, 2005 | Pubmed ID: 16293763 Newly Generated T Cell Receptor Microclusters Initiate and Sustain T Cell Activation by Recruitment of Zap70 and SLP-76 Nature Immunology. Dec, 2005 | Pubmed ID: 16273097 A Dynamic View of the Immunological Synapse Seminars in Immunology. Dec, 2005 | Pubmed ID: 16266811 Actin and Agonist MHC-peptide Complex-dependent T Cell Receptor Microclusters As Scaffolds for Signaling The Journal of Experimental Medicine. Oct, 2005 | Pubmed ID: 16216891 A Molecular Dissection of Lymphocyte Unresponsiveness Induced by Sustained Calcium Signalling Novartis Foundation Symposium. 2005 | Pubmed ID: 15999806 Stable T Cell-dendritic Cell Interactions Precede the Development of Both Tolerance and Immunity in Vivo Nature Immunology. Jul, 2005 | Pubmed ID: 15924144 A Model for CD2/CD58-mediated Adhesion Strengthening Annals of Biomedical Engineering. Apr, 2005 | Pubmed ID: 15909654 ATP Mediates Rapid Microglial Response to Local Brain Injury in Vivo Nature Neuroscience. Jun, 2005 | Pubmed ID: 15895084 ICAM-1 Co-stimulates Target Cells to Facilitate Antigen Presentation Current Opinion in Immunology. Jun, 2005 | Pubmed ID: 15886114 Distinct Role of Lymphocyte Function-associated Antigen-1 in Mediating Effective Cytolytic Activity by Cytotoxic T Lymphocytes Proceedings of the National Academy of Sciences of the United States of America. May, 2005 | Pubmed ID: 15851656 Intravascular Immune Surveillance by CXCR6+ NKT Cells Patrolling Liver Sinusoids PLoS Biology. Apr, 2005 | Pubmed ID: 15799695 Visualizing Dendritic Cell Networks in Vivo Nature Immunology. Dec, 2004 | Pubmed ID: 15543150 A Polarizing Situation Nature Immunology. Oct, 2004 | Pubmed ID: 15454929 Stop and Go Traffic to Tune T Cell Responses Immunity. Sep, 2004 | Pubmed ID: 15357942 T Cell Receptor Antagonism Interferes with MHC Clustering and Integrin Patterning During Immunological Synapse Formation The Journal of Cell Biology. Aug, 2004 | Pubmed ID: 15314068 What is the Importance of the Immunological Synapse? Trends in Immunology. Jun, 2004 | Pubmed ID: 15145322 LFA-1/ICAM-1 Interaction Lowers the Threshold of B Cell Activation by Facilitating B Cell Adhesion and Synapse Formation Immunity. May, 2004 | Pubmed ID: 15142527 Membranes As Messengers in T Cell Adhesion Signaling Nature Immunology. Apr, 2004 | Pubmed ID: 15052266 Calcineurin Imposes T Cell Unresponsiveness Through Targeted Proteolysis of Signaling Proteins Nature Immunology. Mar, 2004 | Pubmed ID: 14973438 Cytotoxic T Lymphocytes Form an Antigen-independent Ring Junction The Journal of Clinical Investigation. Jan, 2004 | Pubmed ID: 14702108 In Silico Models for Cellular and Molecular Immunology: Successes, Promises and Challenges Nature Immunology. Oct, 2003 | Pubmed ID: 14515121 The Immunological Synapse Balances T Cell Receptor Signaling and Degradation Science (New York, N.Y.). Nov, 2003 | Pubmed ID: 14512504 Supported Planar Bilayers in Studies on Immune Cell Adhesion and Communication Journal of Immunological Methods. Jul, 2003 | Pubmed ID: 12957393 In Vivo Imaging Approaches in Animal Models of Rheumatoid Arthritis Arthritis Research & Therapy. 2003 | Pubmed ID: 12823846 Coordination of T Cell Activation and Migration Through Formation of the Immunological Synapse Annals of the New York Academy of Sciences. Apr, 2003 | Pubmed ID: 12727623 Regulation of T Cell Migration Through Formation of Immunological Synapses: the Stop Signal Hypothesis Advances in Experimental Medicine and Biology. 2002 | Pubmed ID: 12405204 Neural and Immunological Synaptic Relations Science (New York, N.Y.). Oct, 2002 | Pubmed ID: 12399580 The Synapse Assembly Model Trends in Immunology. Oct, 2002 | Pubmed ID: 12297422 Correlation of a Dynamic Model for Immunological Synapse Formation with Effector Functions: Two Pathways to Synapse Formation Trends in Immunology. Oct, 2002 | Pubmed ID: 12297421 The Immunological Synapse: Integrins Take the Stage Immunological Reviews. Aug, 2002 | Pubmed ID: 12234366 T-cell Activation: a Multidimensional Signaling Network Current Opinion in Cell Biology. Oct, 2002 | Pubmed ID: 12231352 Cutting Edge: Quantitative Imaging of Raft Accumulation in the Immunological Synapse Journal of Immunology (Baltimore, Md. : 1950). Sep, 2002 | Pubmed ID: 12218094 Shmoos, Rafts, and Uropods- the Many Facets of Cell Polarity Cell. Jul, 2002 | Pubmed ID: 12150993 Immature CD4(+)CD8(+) Thymocytes Form a Multifocal Immunological Synapse with Sustained Tyrosine Phosphorylation Immunity. Jun, 2002 | Pubmed ID: 12121665 The Immunological Synapse Arthritis Research. 2002 | Pubmed ID: 12110130 Stimulation of Naïve T-cell Adhesion and Immunological Synapse Formation by Chemokine-dependent and -independent Mechanisms Immunology. Jul, 2002 | Pubmed ID: 12100716 Polar Redistribution of the Sialoglycoprotein CD43: Implications for T Cell Function Journal of Immunology (Baltimore, Md. : 1950). Apr, 2002 | Pubmed ID: 11937524 WIP Deficiency Reveals a Differential Role for WIP and the Actin Cytoskeleton in T and B Cell Activation Immunity. Feb, 2002 | Pubmed ID: 11869681 T Cell Receptor Signaling Precedes Immunological Synapse Formation Science (New York, N.Y.). Feb, 2002 | Pubmed ID: 11859198 Membrane Domains and the Immunological Synapse: Keeping T Cells Resting and Ready The Journal of Clinical Investigation. Jan, 2002 | Pubmed ID: 11805125 Costimulation and Endogenous MHC Ligands Contribute to T Cell Recognition Nature Immunology. Jan, 2002 | Pubmed ID: 11731799 Fremstilling af perleunderstøttede lipiddobbeltlag til undersøgelse af partikelproduktionen af T-celleimmunsynapser Pablo F. Céspedes1, Michael L. Dustin1 1Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, The University of Oxford JoVE 63130 Immunology and Infection Scanning af HIV-1 Envelope-induceret Virologisk Synapse og signaler på syntetiske lipiddobbeltlagenes Kathleen C. Prins*1,2, Gaia Vasiliver-Shamis*2,3, Michael Cammer1,2, David Depoil1,2, Michael L. Dustin2, Catarina E. Hioe1,4 1Department of Pathology, New York University Langone School of Medicine, 2Program in Molecular Pathogenesis, Marty and Helen Kimmel Center for Biology and Medicine and Skirball Institute for Biomolecular Medicine, 3Laboratory of Molecular Immunogenetics, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, 4Veteran Affairs New York Harbor Healthcare System JoVE 3757 Immunology and Infection
Fremstilling af perleunderstøttede lipiddobbeltlag til undersøgelse af partikelproduktionen af T-celleimmunsynapser Pablo F. Céspedes1, Michael L. Dustin1 1Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, The University of Oxford JoVE 63130 Immunology and Infection
Scanning af HIV-1 Envelope-induceret Virologisk Synapse og signaler på syntetiske lipiddobbeltlagenes Kathleen C. Prins*1,2, Gaia Vasiliver-Shamis*2,3, Michael Cammer1,2, David Depoil1,2, Michael L. Dustin2, Catarina E. Hioe1,4 1Department of Pathology, New York University Langone School of Medicine, 2Program in Molecular Pathogenesis, Marty and Helen Kimmel Center for Biology and Medicine and Skirball Institute for Biomolecular Medicine, 3Laboratory of Molecular Immunogenetics, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, 4Veteran Affairs New York Harbor Healthcare System JoVE 3757 Immunology and Infection