Mihaela Zavolan Computational and Systems Biology, Biozentrum University of Basel Biography Publications Institution JoVE Articles Mihaela Zavolan has not added a biography. If you are Mihaela Zavolan and would like to personalize this page please email our Author Liaison for assistance. Publications The Gcn4 Transcription Factor Reduces Protein Synthesis Capacity and Extends Yeast Lifespan Nature Communications. Sep, 2017 | Pubmed ID: 28878244 Automated Incorporation of Pairwise Dependency in Transcription Factor Binding Site Prediction Using Dinucleotide Weight Tensors PLoS Computational Biology. Jul, 2017 | Pubmed ID: 28753602 TFAP2A is a Component of the ZEB1/2 Network That Regulates TGFB1-induced Epithelial to Mesenchymal Transition Biology Direct. Apr, 2017 | Pubmed ID: 28412966 Explicit Modeling of SiRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results Cell Systems. Feb, 2017 | Pubmed ID: 28215525 High-throughput Identification of C/D Box SnoRNA Targets with CLIP and RiboMeth-seq Nucleic Acids Research. Mar, 2017 | Pubmed ID: 28031372 Patterns of Ribosomal Protein Expression Specify Normal and Malignant Human Cells Genome Biology. Nov, 2016 | Pubmed ID: 27884178 TUT-DIS3L2 is a Mammalian Surveillance Pathway for Aberrant Structured Non-coding RNAs The EMBO Journal. Oct, 2016 | Pubmed ID: 27647875 A Comprehensive Analysis of 3' End Sequencing Data Sets Reveals Novel Polyadenylation Signals and the Repressive Role of Heterogeneous Ribonucleoprotein C on Cleavage and Polyadenylation Genome Research. 08, 2016 | Pubmed ID: 27382025 Corrigendum to "Quantifying the Strength of MiRNA-target Interactions" [Methods (2015) 90-99] Methods (San Diego, Calif.). Jul, 2016 | Pubmed ID: 27372217 Redesigning CLIP for Efficiency, Accuracy and Speed Nature Methods. May, 2016 | Pubmed ID: 27243472 An Updated Human SnoRNAome Nucleic Acids Research. Jun, 2016 | Pubmed ID: 27174936 Roquin Recognizes a Non-canonical Hexaloop Structure in the 3'-UTR of Ox40 Nature Communications. Mar, 2016 | Pubmed ID: 27010430 Accurate Transcriptome-wide Prediction of MicroRNA Targets and Small Interfering RNA Off-targets with MIRZA-G Nucleic Acids Research. Oct, 2015 | Pubmed ID: 26365243 Cooperative Target MRNA Destabilization and Translation Inhibition by MiR-58 MicroRNA Family in C. Elegans Genome Research. Nov, 2015 | Pubmed ID: 26232411 Comparative Assessment of Methods for the Computational Inference of Transcript Isoform Abundance from RNA-seq Data Genome Biology. Jul, 2015 | Pubmed ID: 26201343 Inferring Gene Expression Regulatory Networks from High-throughput Measurements Methods (San Diego, Calif.). Sep, 2015 | Pubmed ID: 26188125 MiR-184 Regulates Pancreatic β-Cell Function According to Glucose Metabolism The Journal of Biological Chemistry. Aug, 2015 | Pubmed ID: 26152724 Quantifying the Strength of MiRNA-target Interactions Methods (San Diego, Calif.). Sep, 2015 | Pubmed ID: 25892562 Reflections on the RNA World RNA (New York, N.Y.). Apr, 2015 | Pubmed ID: 25780126 Accurate Transcriptome-wide Prediction of MicroRNA Targets and Small Interfering RNA Off-targets with MIRZA-G Nucleic Acids Research. Feb, 2015 | Pubmed ID: 25628353 MiR-CLIP Capture of a MiRNA Targetome Uncovers a LincRNA H19-miR-106a Interaction Nature Chemical Biology. Feb, 2015 | Pubmed ID: 25531890 Global 3' UTR Shortening Has a Limited Effect on Protein Abundance in Proliferating T Cells Nature Communications. 2014 | Pubmed ID: 25413384 Reconstitution of CPSF Active in Polyadenylation: Recognition of the Polyadenylation Signal by WDR33 Genes & Development. Nov, 2014 | Pubmed ID: 25301781 Embryonic Stem Cell-specific MicroRNAs Contribute to Pluripotency by Inhibiting Regulators of Multiple Differentiation Pathways Nucleic Acids Research. Aug, 2014 | Pubmed ID: 25030899 Identification and Consequences of MiRNA-target Interactions--beyond Repression of Gene Expression Nature Reviews. Genetics. Sep, 2014 | Pubmed ID: 25022902 Structural and Functional Implications of the QUA2 Domain on RNA Recognition by GLD-1 Nucleic Acids Research. Jul, 2014 | Pubmed ID: 24838563 Fifteen Years SIB Swiss Institute of Bioinformatics: Life Science Databases, Tools and Support Nucleic Acids Research. Jul, 2014 | Pubmed ID: 24792157 MicroRNA-7a Regulates Pancreatic β Cell Function The Journal of Clinical Investigation. Jun, 2014 | Pubmed ID: 24789908 Widespread Context Dependency of MicroRNA-mediated Regulation Genome Research. Jun, 2014 | Pubmed ID: 24668909 PAR-CLIP (Photoactivatable Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation): a Step-by-step Protocol to the Transcriptome-wide Identification of Binding Sites of RNA-binding Proteins Methods in Enzymology. 2014 | Pubmed ID: 24581442 ISMARA: Automated Modeling of Genomic Signals As a Democracy of Regulatory Motifs Genome Research. May, 2014 | Pubmed ID: 24515121 Seq and CLIP Through the MiRNA World Genome Biology. Jan, 2014 | Pubmed ID: 24460822 TSSer: an Automated Method to Identify Transcription Start Sites in Prokaryotic Genomes from Differential RNA Sequencing Data Bioinformatics (Oxford, England). Apr, 2014 | Pubmed ID: 24371151 Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell Cell Metabolism. Jan, 2014 | Pubmed ID: 24361012 Means to an End: Mechanisms of Alternative Polyadenylation of Messenger RNA Precursors Wiley Interdisciplinary Reviews. RNA. Mar-Apr, 2014 | Pubmed ID: 24243805 3'-UTR Poly(T/U) Tract Deletions and Altered Expression of EWSR1 Are a Hallmark of Mismatch Repair-deficient Cancers Cancer Research. Jan, 2014 | Pubmed ID: 24158095 Timescales and Bottlenecks in MiRNA-dependent Gene Regulation Molecular Systems Biology. Dec, 2013 | Pubmed ID: 24301800 Modulation of Epigenetic Regulators and Cell Fate Decisions by MiRNAs Epigenomics. Dec, 2013 | Pubmed ID: 24283881 Modeling the Binding Specificity of the RNA-binding Protein GLD-1 Suggests a Function of Coding Region-located Sites in Translational Repression RNA (New York, N.Y.). Oct, 2013 | Pubmed ID: 23974436 Translation-dependent Displacement of UPF1 from Coding Sequences Causes Its Enrichment in 3' UTRs Nature Structural & Molecular Biology. Aug, 2013 | Pubmed ID: 23832275 Insights into SnoRNA Biogenesis and Processing from PAR-CLIP of SnoRNA Core Proteins and Small RNA Sequencing Genome Biology. May, 2013 | Pubmed ID: 23706177 Analysis of CDS-located MiRNA Target Sites Suggests That They Can Effectively Inhibit Translation Genome Research. Apr, 2013 | Pubmed ID: 23335364 A Biophysical MiRNA-mRNA Interaction Model Infers Canonical and Noncanonical Targets Nature Methods. Mar, 2013 | Pubmed ID: 23334102 Dicer Partners Expand the Repertoire of MiRNA Targets Genome Biology. Nov, 2012 | Pubmed ID: 23194401 Argonaute CLIP--a Method to Identify in Vivo Targets of MiRNAs Methods (San Diego, Calif.). Oct, 2012 | Pubmed ID: 23022257 Genome-wide Analysis of Pre-mRNA 3' End Processing Reveals a Decisive Role of Human Cleavage Factor I in the Regulation of 3' UTR Length Cell Reports. Jun, 2012 | Pubmed ID: 22813749 MicroRNA 194 是烫 6 成人肝脏和控件表达式中的转录因子 1 HNF1α Tcf1） 的目标。 Hepatology (Baltimore, Md.). Jan, 2012 | Pubmed ID: 21887698 卡波氏肉瘤疱疹病毒 Microrna 目标半胱氨酸蛋白酶 3 和调节细胞凋亡。 PLoS Pathogens. Dec, 2011 | Pubmed ID: 22174674 PAPD5，以非同寻常的 RNA 结合主题可视点 Poly(A) 聚合酶。 RNA (New York, N.Y.). Sep, 2011 | Pubmed ID: 21788334 Microrna 103 和 107 调节胰岛素敏感性。 Nature. Jun, 2011 | Pubmed ID: 21654750 剪辑方法识别 RNA 结合蛋白的结合位点的定量分析。 Nature Methods. Jul, 2011 | Pubmed ID: 21572407 守恒的代短产品 PiRNA 位点。 BMC Genomics. 2011 | Pubmed ID: 21247452 CLIPZ： 数据库和分析环境的实验确定的绑定站点的 RNA 结合蛋白。 Nucleic Acids Research. Jan, 2011 | Pubmed ID: 21087992 人剪接因子 SF1 原位 Pre MRNA 指标的分析表明，剪接中的函数。 Nucleic Acids Research. Mar, 2011 | Pubmed ID: 21062807 破译基因表达的转录控制 RNA 结合蛋白的作用。 Briefings in Functional Genomics. Dec, 2010 | Pubmed ID: 21127008 UPF1 组合式在癌细胞中的表达蛋白质组学揭示了自动调节功能 HnRNP A2/B1 介导废话介导 MRNA 衰变替代拼接造成。 BMC Genomics. 2010 | Pubmed ID: 20946641 转录过程全由 PAR 剪辑 RNA 结合蛋白和 MicroRNA 目标站点的标识。 Cell. Apr, 2010 | Pubmed ID: 20371350 MicroRNA 活动压制在小鼠卵母细胞中。 Current Biology : CB. Feb, 2010 | Pubmed ID: 20116252 姆比-52 （SNORD 115) 核仁蛋白加工成较小 RNAs，以及规管剪接。 Human Molecular Genetics. Apr, 2010 | Pubmed ID: 20053671 阿耳戈英雄/EIF2C-米尔配合物的 MRNA 绑定和退化的米尔目标序列和结构功能的相对贡献。 Genome Research. Nov, 2009 | Pubmed ID: 19767416 表达式和核仁小爱泼斯坦-巴尔病毒基因组 RNA 的加工。 PLoS Pathogens. Aug, 2009 | Pubmed ID: 19680535 MirZ： 综合的 MicroRNA 表达图谱与目标预测资源。 Nucleic Acids Research. Jul, 2009 | Pubmed ID: 19468042 控制增长逮捕和人髓系白血病细胞分化的转录网络。 Nature Genetics. May, 2009 | Pubmed ID: 19377474 和平号空间站 375 维护正常胰腺 α 和 β 细胞。 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2009 | Pubmed ID: 19289822 米尔原位杂交技术在甲醛和 EDC 固定的组织。 Nature Methods. Feb, 2009 | Pubmed ID: 19137005 人类阿耳戈英雄含核糖核蛋白复合物和其绑定的目标基因的分子特征。 RNA (New York, N.Y.). Dec, 2008 | Pubmed ID: 18978028 人类 PUF 家族蛋白的 MRNA 指标的比较分析表明与米尔的规管制度开展广泛互动。 PloS One. 2008 | Pubmed ID: 18776931 高架的表达的和平号空间站-17-92 Polycistron 和和平号空间站-21 Hepadnavirus 相关肝细胞癌的恶性表型作出了贡献。 The American Journal of Pathology. Sep, 2008 | Pubmed ID: 18688024 Microrna 控制通过调控小鼠胚胎干细胞中的转录 Repressors De Novo DNA 甲基化。 Nature Structural & Molecular Biology. Mar, 2008 | Pubmed ID: 18311153 全长扩增的计算分析揭示了频繁转录和拼接程序之间的耦合。 DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes. Apr, 2008 | Pubmed ID: 18276623 小 RNA 克隆数据的计算分析。 Methods (San Diego, Calif.). Jan, 2008 | Pubmed ID: 18158128 选择和确定目标特异性绞线钢绞线具体 5'-O-甲基化 SiRNA 双工控制指南。 RNA (New York, N.Y.). Feb, 2008 | Pubmed ID: 18094121 人类肝三角洲-氨基酮戊酸合成酶的胆汁酸的规管。 Hepatology (Baltimore, Md.). Dec, 2007 | Pubmed ID: 17975826 丙型肝炎病毒感染和复制影响细胞的辅助因子。 Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17616579 基于小 RNA 库测序哺乳动物 MicroRNA 表达图谱。 Cell. Jun, 2007 | Pubmed ID: 17604727 马立克氏病病毒类型 2 （MDV-2)-编码的 Microrna 与那些由 MDV 1 编码显示没有序列养护。 Journal of Virology. Jul, 2007 | Pubmed ID: 17459919 米尔目标使用进化的养护和途径分析推理。 BMC Bioinformatics. 2007 | Pubmed ID: 17331257 定量技术建立一个新型的 MicroRNA 慢性淋巴细胞白血病的配置文件。 Blood. Jun, 2007 | Pubmed ID: 17327404 对人胚胎肾 293 细胞 MRNA 水平切块机和阿耳戈英雄下调的影响。 Nucleic Acids Research. 2006 | Pubmed ID: 16971455 一类新型的小 RNAs 绑定到蜜蛋白在小鼠睾丸中。 Nature. Jul, 2006 | Pubmed ID: 16751777 类型和可供选择的流行拼接形式。 Current Opinion in Structural Biology. Jun, 2006 | Pubmed ID: 16713247 一个简单的物理模型预测小外显子的长度变化。 PLoS Genetics. Apr, 2006 | Pubmed ID: 16683028 水疗中心： 一种概率算法拼接的对齐方式。 PLoS Genetics. Apr, 2006 | Pubmed ID: 16683023 病毒编码 Microrna： 基因表达的新型监管机构。 Trends in Microbiology. Apr, 2006 | Pubmed ID: 16531046 单元格类型特定的 Microrna 对目标基因表达的特征码。 Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006 | Pubmed ID: 16477010 聚集 Microrna 使用 Ab 从头预测方法的标识。 BMC Bioinformatics. 2005 | Pubmed ID: 16274478 发展米尔斑马鱼由小 RNA 克隆的配置文件。 Genes & Development. Jun, 2005 | Pubmed ID: 15937218 疱疹病毒家族的 Microrna 的标识。 Nature Methods. Apr, 2005 | Pubmed ID: 15782219 人类免疫缺陷病毒 Cytopathicity 通过使用一种新方法的皮下细胞培养病毒动力学分析。 Journal of Virology. Apr, 2005 | Pubmed ID: 15767404 病毒编码 Microrna 的标识。 Science (New York, N.Y.). Apr, 2004 | Pubmed ID: 15118162 粉碎调控位点在 DNA 中的人-鼠序列比较。 Proceedings / IEEE Computer Society Bioinformatics Conference. IEEE Computer Society Bioinformatics Conference. 2003 | Pubmed ID: 16452803 果蝇果蝇发育过程小 RNA 配置文件。 Developmental Cell. Aug, 2003 | Pubmed ID: 12919683 衰变率人体分泌： 功能特征和序列属性关联。 Genome Research. Aug, 2003 | Pubmed ID: 12902380 含锌指蛋白的鼠标转录过程的系统表征。 Genome Research. Jun, 2003 | Pubmed ID: 12819142 替代启动、 拼接，和多样性的编码由鼠标转录 MRNA 誊本协议终止的影响。 Genome Research. Jun, 2003 | Pubmed ID: 12819126 拼接中通过对小鼠基因组映射来确定鼠标全长扩增的变化。 Genome Research. Sep, 2002 | Pubmed ID: 12213775 概率聚类的序列： 推断的比较基因组学的新细菌 Regulons。 Proceedings of the National Academy of Sciences of the United States of America. May, 2002 | Pubmed ID: 12032281 3 A-seq2 的末端测序库的研制 Georges Martin1, Ralf Schmidt1, Andreas J. Gruber1, Souvik Ghosh1, Walter Keller1, Mihaela Zavolan1,2 1Computational and Systems Biology, Biozentrum, University of Basel, 2Swiss Institute of Bioinformatics, Biozentrum, University of Basel JoVE 56129 Biology PAR剪辑 - 一个方法来确定全转录组学，RNA结合蛋白的结合位点 Markus Hafner1, Markus Landthaler2, Lukas Burger3, Mohsen Khorshid3, Jean Hausser4, Philipp Berninger4, Andrea Rothballer1, Manuel Ascano1, Anna-Carina Jungkamp2, Mathias Munschauer2, Alexander Ulrich1, Greg S. Wardle1, Scott Dewell5, Mihaela Zavolan3, Thomas Tuschl1 1Howard Hughes Medical Institute, Laboratory of RNA Molecular Biology, Rockefeller University, 2Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine, 3Biozentrum der Universität Basel and Swiss Institute of Bioinformatics (SIB), 4Biozentrum der Universität Basel and Swiss Institute of Bioinformatics (SIB), 5Genomics Resource Center, Rockefeller University JoVE 2034 Biology
3 A-seq2 的末端测序库的研制 Georges Martin1, Ralf Schmidt1, Andreas J. Gruber1, Souvik Ghosh1, Walter Keller1, Mihaela Zavolan1,2 1Computational and Systems Biology, Biozentrum, University of Basel, 2Swiss Institute of Bioinformatics, Biozentrum, University of Basel JoVE 56129 Biology
PAR剪辑 - 一个方法来确定全转录组学，RNA结合蛋白的结合位点 Markus Hafner1, Markus Landthaler2, Lukas Burger3, Mohsen Khorshid3, Jean Hausser4, Philipp Berninger4, Andrea Rothballer1, Manuel Ascano1, Anna-Carina Jungkamp2, Mathias Munschauer2, Alexander Ulrich1, Greg S. Wardle1, Scott Dewell5, Mihaela Zavolan3, Thomas Tuschl1 1Howard Hughes Medical Institute, Laboratory of RNA Molecular Biology, Rockefeller University, 2Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine, 3Biozentrum der Universität Basel and Swiss Institute of Bioinformatics (SIB), 4Biozentrum der Universität Basel and Swiss Institute of Bioinformatics (SIB), 5Genomics Resource Center, Rockefeller University JoVE 2034 Biology
