Ming-Daw Tsai

Publications

• TIFA Protein Expression is Associated with Pulmonary Arterial Hypertension
  Scientific Reports. Jul, 2021  |   Pubmed ID: 34238983
• Synthesis of a Biotinylated Heptose 1,7-bisphosphate Analogue, a Probe to Study Immunity and Inflammation
  Organic & Biomolecular Chemistry. Jun, 2021  |   Pubmed ID: 33988211
• Identification of Fidelity-governing Factors in Human Recombinases DMC1 and RAD51 from Cryo-EM Structures
  Nature Communications. 01, 2021  |   Pubmed ID: 33446654
• Vibrio Cholerae Biofilm Scaffolding Protein RbmA Shows an Intrinsic, Phosphate-dependent Autoproteolysis Activity
  IUBMB Life. Feb, 2021  |   Pubmed ID: 33372380
• Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues
  Biochemistry. 06, 2020  |   Pubmed ID: 32484330
• Nonhydrolyzable Heptose Bis- and Monophosphate Analogues Modulate Pro-inflammatory TIFA-NF-κB Signaling
  Chembiochem : a European Journal of Chemical Biology. 10, 2020  |   Pubmed ID: 32452604
• 9°N DNA Polymerase Exhibits 3'-esterase Activity That Can Be Harnessed for DNA Sequencing
  Communications Biology. 2019  |   Pubmed ID: 31240262
• Human DNA Polymerase μ Can Use a Noncanonical Mechanism for Multiple Mn-Mediated Functions
  Journal of the American Chemical Society. 05, 2019  |   Pubmed ID: 31067051
• Binding and Enhanced Binding Between Key Immunity Proteins TRAF6 and TIFA
  Chembiochem : a European Journal of Chemical Biology. 01, 2019  |   Pubmed ID: 30378729
• Catalytic Mechanism of DNA Polymerases-Two Metal Ions or Three?
  Protein Science : a Publication of the Protein Society. 02, 2019  |   Pubmed ID: 30368961
• Twist and Turn: a Revised Structural View on the Unpaired Bubble of Class II CPD Photolyase in Complex with Damaged DNA
  IUCrJ. Sep, 2018  |   Pubmed ID: 30224964
• Structure of the Bifunctional Cryptochrome ACRY from Chlamydomonas Reinhardtii
  Nucleic Acids Research. 09, 2018  |   Pubmed ID: 30032195
• TagF-mediated Repression of Bacterial Type VI Secretion Systems Involves a Direct Interaction with the Cytoplasmic Protein Fha
  The Journal of Biological Chemistry. 06, 2018  |   Pubmed ID: 29599293
• STRENDA DB: Enabling the Validation and Sharing of Enzyme Kinetics Data
  The FEBS Journal. 06, 2018  |   Pubmed ID: 29498804
• Phospho-Priming Confers Functionally Relevant Specificities for Rad53 Kinase Autophosphorylation
  Biochemistry. 09, 2017  |   Pubmed ID: 28858528
• Aurora A and NF-κB Survival Pathway Drive Chemoresistance in Acute Myeloid Leukemia Via the TRAF-Interacting Protein TIFA
  Cancer Research. 01, 2017  |   Pubmed ID: 28069801
• TIFA As a Crucial Mediator for NLRP3 Inflammasome
  Proceedings of the National Academy of Sciences of the United States of America. 12, 2016  |   Pubmed ID: 27965388
• The Nucleolar Protein NIFK Promotes Cancer Progression Via CK1α/β-catenin in Metastasis and Ki-67-dependent Cell Proliferation
  ELife. Mar, 2016  |   Pubmed ID: 26984280
• Protein Arginine Methyltransferase 8: Tetrameric Structure and Protein Substrate Specificity
  Biochemistry. Dec, 2015  |   Pubmed ID: 26529540
• Uncovering the Mechanism of Forkhead-Associated Domain-Mediated TIFA Oligomerization That Plays a Central Role in Immune Responses
  Biochemistry. Oct, 2015  |   Pubmed ID: 26389808
• The RNA Recognition Motif of NIFK is Required for RRNA Maturation During Cell Cycle Progression
  RNA Biology. 2015  |   Pubmed ID: 25826659
• A Ribonuclease Coordinates SiRNA Amplification and MRNA Cleavage During RNAi
  Cell. Jan, 2015  |   Pubmed ID: 25635455
• Use of Quantitative Mass Spectrometric Analysis to Elucidate the Mechanisms of Phospho-priming and Auto-activation of the Checkpoint Kinase Rad53 in Vivo
  Molecular & Cellular Proteomics : MCP. Feb, 2014  |   Pubmed ID: 33498138
• PP2A and Aurora Differentially Modify Cdc13 to Promote Telomerase Release from Telomeres at G2/M Phase
  Nature Communications. Nov, 2014  |   Pubmed ID: 25387524
• Ultrafast Water Dynamics at the Interface of the Polymerase-DNA Binding Complex
  Biochemistry. Aug, 2014  |   Pubmed ID: 25105470
• Multiple Complexes of Long Aliphatic N-acyltransferases Lead to Synthesis of 2,6-diacylated/2-acyl-substituted Glycopeptide Antibiotics, Effectively Killing Vancomycin-resistant Enterococcus
  Journal of the American Chemical Society. Aug, 2014  |   Pubmed ID: 25095906
• Structure and Mechanism of a Nonhaem-iron SAM-dependent C-methyltransferase and Its Engineering to a Hydratase and an O-methyltransferase
  Acta Crystallographica. Section D, Biological Crystallography. Jun, 2014  |   Pubmed ID: 24914966
• How DNA Polymerases Catalyze DNA Replication, Repair, and Mutation
  Biochemistry. May, 2014  |   Pubmed ID: 24716436
• Fha Interaction with Phosphothreonine of TssL Activates Type VI Secretion in Agrobacterium Tumefaciens
  PLoS Pathogens. Mar, 2014  |   Pubmed ID: 24626341
• How a Low-fidelity DNA Polymerase Chooses Non-Watson-Crick from Watson-Crick Incorporation
  Journal of the American Chemical Society. Apr, 2014  |   Pubmed ID: 24617852
• Tight Regulation of a Timed Nuclear Import Wave of EKLF by PKCθ and FOE During Pro-E to Baso-E Transition
  Developmental Cell. Feb, 2014  |   Pubmed ID: 24576425
• Biosynthesis of Streptolidine Involved Two Unexpected Intermediates Produced by a Dihydroxylase and a Cyclase Through Unusual Mechanisms
  Angewandte Chemie (International Ed. in English). Feb, 2014  |   Pubmed ID: 24505011
• Use of Quantitative Mass Spectrometric Analysis to Elucidate the Mechanisms of Phospho-priming and Auto-activation of the Checkpoint Kinase Rad53 in Vivo
  Molecular & Cellular Proteomics : MCP. Feb, 2014  |   Pubmed ID: 24302356
• Interaction Between Salt-inducible Kinase 2 (SIK2) and P97/valosin-containing Protein (VCP) Regulates Endoplasmic Reticulum (ER)-associated Protein Degradation in Mammalian Cells
  The Journal of Biological Chemistry. Nov, 2013  |   Pubmed ID: 24129571
• Molecular Basis of the Essential S Phase Function of the Rad53 Checkpoint Kinase
  Molecular and Cellular Biology. Aug, 2013  |   Pubmed ID: 23754745
• Evidence That P12, a Specific Variant of P16(INK4A), Plays a Suppressive Role in Human Pancreatic Carcinogenesis
  Biochemical and Biophysical Research Communications. Jun, 2013  |   Pubmed ID: 23727582
• Histone Demethylase RBP2 Promotes Lung Tumorigenesis and Cancer Metastasis
  Cancer Research. Aug, 2013  |   Pubmed ID: 23722541
• Phosphorylation of MRNA Decapping Protein Dcp1a by the ERK Signaling Pathway During Early Differentiation of 3T3-L1 Preadipocytes
  PloS One. 2013  |   Pubmed ID: 23637887
• Ubc9 Acetylation Modulates Distinct SUMO Target Modification and Hypoxia Response
  The EMBO Journal. Mar, 2013  |   Pubmed ID: 23395904
• Reversible Acetylation Regulates Salt-inducible Kinase (SIK2) and Its Function in Autophagy
  The Journal of Biological Chemistry. Mar, 2013  |   Pubmed ID: 23322770
• Loss of the Oxidative Stress Sensor NPGPx Compromises GRP78 Chaperone Activity and Induces Systemic Disease
  Molecular Cell. Dec, 2012  |   Pubmed ID: 23123197
• Amino Acid Substitutions of MagA in Klebsiella Pneumoniae Affect the Biosynthesis of the Capsular Polysaccharide
  PloS One. 2012  |   Pubmed ID: 23118860
• Intermolecular Binding Between TIFA-FHA and TIFA-pT Mediates Tumor Necrosis Factor Alpha Stimulation and NF-κB Activation
  Molecular and Cellular Biology. Jul, 2012  |   Pubmed ID: 22566686
• SUMOylation of Blimp-1 is Critical for Plasma Cell Differentiation
  EMBO Reports. Jun, 2012  |   Pubmed ID: 22555612
• Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68
  Biochemistry. Jan, 2012  |   Pubmed ID: 22211259
• Kinetic Mechanism of Active Site Assembly and Chemical Catalysis of DNA Polymerase β
  Biochemistry. Nov, 2011  |   Pubmed ID: 22010960
• E339...R416 Salt Bridge of Nucleoprotein As a Feasible Target for Influenza Virus Inhibitors
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2011  |   Pubmed ID: 21930946
• Protein Kinase A-mediated Serine 35 Phosphorylation Dissociates Histone H1.4 from Mitotic Chromosome
  The Journal of Biological Chemistry. Oct, 2011  |   Pubmed ID: 21852232
• Functions of Some Capsular Polysaccharide Biosynthetic Genes in Klebsiella Pneumoniae NTUH K-2044
  PloS One. 2011  |   Pubmed ID: 21765903
• Regulatory Mechanisms of Tumor Suppressor P16(INK4A) and Their Relevance to Cancer
  Biochemistry. Jun, 2011  |   Pubmed ID: 21619050
• Interception of Teicoplanin Oxidation Intermediates Yields New Antimicrobial Scaffolds
  Nature Chemical Biology. May, 2011  |   Pubmed ID: 21478878
• The Histone H3K36 Demethylase Rph1/KDM4 Regulates the Expression of the Photoreactivation Gene PHR1
  Nucleic Acids Research. May, 2011  |   Pubmed ID: 21296759
• Regioselective Deacetylation Based on Teicoplanin-complexed Orf2* Crystal Structures
  Molecular BioSystems. Apr, 2011  |   Pubmed ID: 21267472
• High-throughput Identification of Compounds Targeting Influenza RNA-dependent RNA Polymerase Activity
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010  |   Pubmed ID: 20974907
• Database Search Algorithm for Identification of Intact Cross-links in Proteins and Peptides Using Tandem Mass Spectrometry
  Journal of Proteome Research. Jul, 2010  |   Pubmed ID: 20469931
• Contribuciones De Conservado TPLH Tetrapeptides a La Estabilidad Conformacional De Ankyrin Repetición Las Proteínas
  Journal of Molecular Biology. May, 2010  |   Pubmed ID: 20398677
• Unique Catalytic Mechanism of Phosphatidylinositol-specific Phospholipase C from Streptomyces Antibioticus
  Journal of the American Chemical Society. Feb, 2010  |   Pubmed ID: 20052980
• JNK-mediated Turnover and Stabilization of the Transcription Factor P45/NF-E2 During Differentiation of Murine Erythroleukemia Cells
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010  |   Pubmed ID: 19966288
• Unambiguous Determination of Isobaric Histone Modifications by Reversed-phase Retention Time and High-mass Accuracy
  Analytical Biochemistry. Jan, 2010  |   Pubmed ID: 19699711
• Trans-cyclization of Phosphatidylinositol Catalyzed by Phospholipase C from Streptomyces Antibioticus
  Journal of the American Chemical Society. Jun, 2009  |   Pubmed ID: 19492832
• AMP-activated Protein Kinase Functionally Phosphorylates Endothelial Nitric Oxide Synthase Ser633
  Circulation Research. Feb, 2009  |   Pubmed ID: 19131647
• Humoral Immunity Against Capsule Polysaccharide Protects the Host from MagA+ Klebsiella Pneumoniae-induced Lethal Disease by Evading Toll-like Receptor 4 Signaling
  Infection and Immunity. Feb, 2009  |   Pubmed ID: 19015249
• Mismatched and Matched DNTP Incorporation by DNA Polymerase Beta Proceed Via Analogous Kinetic Pathways
  Biochemistry. Sep, 2008  |   Pubmed ID: 18717589
• Altered Order of Substrate Binding by DNA Polymerase X from African Swine Fever Virus
  Biochemistry. Jul, 2008  |   Pubmed ID: 18598057
• Diphosphothreonine-specific Interaction Between an SQ/TQ Cluster and an FHA Domain in the Rad53-Dun1 Kinase Cascade
  Molecular Cell. Jun, 2008  |   Pubmed ID: 18570878
• Mismatched DNTP Incorporation by DNA Polymerase Beta Does Not Proceed Via Globally Different Conformational Pathways
  Nucleic Acids Research. May, 2008  |   Pubmed ID: 18385153
• Solution Structures of 2 : 1 and 1 : 1 DNA Polymerase-DNA Complexes Probed by Ultracentrifugation and Small-angle X-ray Scattering
  Nucleic Acids Research. Feb, 2008  |   Pubmed ID: 18084022
• A Unique Flavin Mononucleotide-linked Primary Alcohol Oxidase for Glycopeptide A40926 Maturation
  Journal of the American Chemical Society. Nov, 2007  |   Pubmed ID: 17935335
• Disección De Interacción De Proteínas E Inhibición De CDK4 En La Oncogénico Versus Tumor Suprimir Funciones De Gankyrin Y P16
  Journal of Molecular Biology. Nov, 2007  |   Pubmed ID: 17881001
• Identification of Histone Demethylases in Saccharomyces Cerevisiae
  The Journal of Biological Chemistry. May, 2007  |   Pubmed ID: 17369256
• ASFV DNA Polymerse X is Extremely Error-prone Under Diverse Assay Conditions and Within Multiple DNA Sequence Contexts
  Biochemistry. Dec, 2006  |   Pubmed ID: 17144676
• Glycopeptide Biosynthesis: Dbv21/Orf2 from Dbv/tcp Gene Clusters Are N-Ac-Glm Teicoplanin Pseudoaglycone Deacetylases and Orf15 from Cep Gene Cluster is a Glc-1-P Thymidyltransferase
  Journal of the American Chemical Society. Oct, 2006  |   Pubmed ID: 17044690