Mira Edgerton

Publications

• Ras1 Inactivation Increases Resistance to Phagosomal Killing by Human Neutrophils
  Infection and Immunity. Sep, 2018  |   Pubmed ID: 30249746
• Methodologies for and Evaluation of Efficacy of Antifungal and Antibiofilm Agents and Surface Coatings Against Fungal Biofilms
  Microbial Cell (Graz, Austria). 06, 2018  |   Pubmed ID: 29992128
• Salivary Metals, Age, and Gender Correlate with Cultivable Oral Carriage Levels
  Journal of Oral Microbiology. 2018  |   Pubmed ID: 29686781
• Fluconazole-Resistant Candida Auris Is Susceptible to Salivary Histatin 5 Killing and to Intrinsic Host Defenses
  Antimicrobial Agents and Chemotherapy. Feb, 2018  |   Pubmed ID: 29158282
• Real-Time Approach to Flow Cell Imaging of Candida Albicans Biofilm Development
  Journal of Fungi (Basel, Switzerland). Mar, 2017  |   Pubmed ID: 29371532
• An Acquired Mechanism of Antifungal Drug Resistance Simultaneously Enables Candida Albicans to Escape from Intrinsic Host Defenses
  PLoS Pathogens. Sep, 2017  |   Pubmed ID: 28953977
• Candida Albicans Sap6 Amyloid Regions Function in Cellular Aggregation and Zinc Binding, and Contribute to Zinc Acquisition
  Scientific Reports. Jun, 2017  |   Pubmed ID: 28588252
• Structural Characterization of Histatin 5-Spermidine Conjugates: A Combined Experimental and Theoretical Study
  Journal of Chemical Information and Modeling. 06, 2017  |   Pubmed ID: 28586222
• Human Salivary Protein Histatin 5 Has Potent Bactericidal Activity Against ESKAPE Pathogens
  Frontiers in Cellular and Infection Microbiology. 2017  |   Pubmed ID: 28261570
• Candida Glabrata Binding to Candida Albicans Hyphae Enables Its Development in Oropharyngeal Candidiasis
  PLoS Pathogens. Mar, 2016  |   Pubmed ID: 27029023
• Signalling Mucin Msb2 Regulates Adaptation to Thermal Stress in Candida Albicans
  Molecular Microbiology. 05, 2016  |   Pubmed ID: 26749104
• Innate Immunity and Saliva in Candida Albicans-mediated Oral Diseases
  Journal of Dental Research. Apr, 2016  |   Pubmed ID: 26747422
• Candida Albicans Shed Msb2 and Host Mucins Affect the Candidacidal Activity of Salivary Hst 5
  Pathogens (Basel, Switzerland). Oct, 2015  |   Pubmed ID: 26529023
• Novel Aggregation Properties of Candida Albicans Secreted Aspartyl Proteinase Sap6 Mediate Virulence in Oral Candidiasis
  Infection and Immunity. Jul, 2015  |   Pubmed ID: 25870228
• Candida Albicans Cek1 Mitogen-activated Protein Kinase Signaling Enhances Fungicidal Activity of Salivary Histatin 5
  Antimicrobial Agents and Chemotherapy. 2015  |   Pubmed ID: 25824232
• Iron Binding Modulates Candidacidal Properties of Salivary Histatin 5
  Journal of Dental Research. Jan, 2015  |   Pubmed ID: 25365968
• How Does It Kill?: Understanding the Candidacidal Mechanism of Salivary Histatin 5
  Eukaryotic Cell. Aug, 2014  |   Pubmed ID: 24951439
• Iron-responsive Chromatin Remodelling and MAPK Signalling Enhance Adhesion in Candida Albicans
  Molecular Microbiology. Jul, 2014  |   Pubmed ID: 24889932
• Histatin 5-spermidine Conjugates Have Enhanced Fungicidal Activity and Efficacy As a Topical Therapeutic for Oral Candidiasis
  Antimicrobial Agents and Chemotherapy. 2014  |   Pubmed ID: 24247141
• Histatin 5 Resistance of Candida Glabrata Can Be Reversed by Insertion of Candida Albicans Polyamine Transporter-encoding Genes DUR3 and DUR31
  PloS One. 2013  |   Pubmed ID: 23613860
• Candida Albicans Flu1-mediated Efflux of Salivary Histatin 5 Reduces Its Cytosolic Concentration and Fungicidal Activity
  Antimicrobial Agents and Chemotherapy. Apr, 2013  |   Pubmed ID: 23380720
• Secreted Aspartic Protease Cleavage of Candida Albicans Msb2 Activates Cek1 MAPK Signaling Affecting Biofilm Formation and Oropharyngeal Candidiasis
  PloS One. 2012  |   Pubmed ID: 23139737
• Histatin 5 Uptake by Candida Albicans Utilizes Polyamine Transporters Dur3 and Dur31 Proteins
  The Journal of Biological Chemistry. Dec, 2011  |   Pubmed ID: 22033918
• CD4(+)CD25(+)Foxp3(+) Regulatory T Cells Promote Th17 Cells in Vitro and Enhance Host Resistance in Mouse Candida Albicans Th17 Cell Infection Model
  Immunity. Mar, 2011  |   Pubmed ID: 21435589
• Th17 Cells and IL-17 Receptor Signaling Are Essential for Mucosal Host Defense Against Oral Candidiasis
  The Journal of Experimental Medicine. Feb, 2009  |   Pubmed ID: 19204111
• Uptake of the Antifungal Cationic Peptide Histatin 5 by Candida Albicans Ssa2p Requires Binding to Non-conventional Sites Within the ATPase Domain
  Molecular Microbiology. Dec, 2008  |   Pubmed ID: 19006817
• Calcium Blocks Fungicidal Activity of Human Salivary Histatin 5 Through Disruption of Binding with Candida Albicans
  Journal of Dental Research. Sep, 2003  |   Pubmed ID: 12939362
• Salivary Histatin 5 and Its Similarities to the Other Antimicrobial Proteins in Human Saliva
  Advances in Dental Research. Dec, 2000  |   Pubmed ID: 11842919
• Salivary Histatin 5 and Human Neutrophil Defensin 1 Kill Candida Albicans Via Shared Pathways
  Antimicrobial Agents and Chemotherapy. Dec, 2000  |   Pubmed ID: 11083633