Naiming Zhou

Publications

• An Overview of Ca(2+) Mobilization Assays in GPCR Drug Discovery
  Expert Opinion on Drug Discovery. Mar, 2017  |   Pubmed ID: 28277837
• Activated Niacin Receptor HCA2 Inhibits Chemoattractant-mediated Macrophage Migration Via Gβγ/PKC/ERK1/2 Pathway and Heterologous Receptor Desensitization
  Scientific Reports. Feb, 2017  |   Pubmed ID: 28186140
• Identification and Functional Characterisation of 5-HT4 Receptor in Sea Cucumber Apostichopus Japonicus (Selenka)
  Scientific Reports. Jan, 2017  |   Pubmed ID: 28059140
• Agonist-Activated Bombyx Corazonin Receptor Is Internalized Via an Arrestin-Dependent and Clathrin-Independent Pathway
  Biochemistry. Jul, 2016  |   Pubmed ID: 27348044
• Agonist-mediated Activation of Bombyx Mori Diapause Hormone Receptor Signals to Extracellular Signal-regulated Kinases 1 and 2 Through Gq-PLC-PKC-dependent Cascade
  Insect Biochemistry and Molecular Biology. Aug, 2016  |   Pubmed ID: 27318251
• Quantitative Analysis of G-protein-coupled Receptor Internalization Using DnaE Intein-based Assay
  Methods in Cell Biology. 2016  |   Pubmed ID: 26928549
• Human Neuropeptide S Receptor Is Activated Via a Gαq Protein-biased Signaling Cascade by a Human Neuropeptide S Analog Lacking the C-terminal 10 Residues
  The Journal of Biological Chemistry. Apr, 2016  |   Pubmed ID: 26865629
• Agonist-induced Activation of Histamine H3 Receptor Signals to Extracellular Signal-regulated Kinases 1 and 2 Through PKC-, PLD-, and EGFR-dependent Mechanisms
  Journal of Neurochemistry. Apr, 2016  |   Pubmed ID: 26826667
• Novel 1-Phenyl-3-hydroxy-4-pyridinone Derivatives As Multifunctional Agents for the Therapy of Alzheimer's Disease
  ACS Chemical Neuroscience. Jan, 2016  |   Pubmed ID: 26479744
• Bombyx Mori Prothoracicostatic Peptide Receptor is Allosterically Activated Via a Gα(i/o)-protein-biased Signalling Cascade by Drosophila Sex Peptide
  The Biochemical Journal. Mar, 2015  |   Pubmed ID: 25422933
• Niacin Activates the PI3K/Akt Cascade Via PKC- and EGFR-transactivation-dependent Pathways Through Hydroxyl-carboxylic Acid Receptor 2
  PloS One. 2014  |   Pubmed ID: 25375133
• Activation of BNGR-A24 by Direct Interaction with Tachykinin-related Peptides from the Silkworm Bombyx Mori Leads to the Gq- and Gs-coupled Signaling Cascades
  Biochemistry. Oct, 2014  |   Pubmed ID: 25275886
• Differential Requirements of Arrestin-3 and Clathrin for Ligand-dependent and -independent Internalization of Human G Protein-coupled Receptor 40
  Cellular Signalling. Nov, 2014  |   Pubmed ID: 25038452
• Involvement of β-arrestin-2 and Clathrin in Agonist-mediated Internalization of the Human Cannabinoid CB2 Receptor
  Current Molecular Pharmacology. 2014  |   Pubmed ID: 25023974
• Melatonin Receptor Type 1 Signals to Extracellular Signal-regulated Kinase 1 and 2 Via Gi and Gs Dually Coupled Pathways in HEK-293 Cells
  Biochemistry. May, 2014  |   Pubmed ID: 24724723
• Activation of Bombyx Neuropeptide G Protein-coupled Receptor A4 Via a Gαi-dependent Signaling Pathway by Direct Interaction with Neuropeptide F from Silkworm, Bombyx Mori
  Insect Biochemistry and Molecular Biology. Feb, 2014  |   Pubmed ID: 24374022
• Activation of CAMP-response Element-binding Protein is Positively Regulated by PKA and Calcium-sensitive Calcineurin and Negatively by PKC in Insect
  Insect Biochemistry and Molecular Biology. Nov, 2013  |   Pubmed ID: 24018109
• The Second Intracellular Loop of the Human Cannabinoid CB2 Receptor Governs G Protein Coupling in Coordination with the Carboxyl Terminal Domain
  PloS One. 2013  |   Pubmed ID: 23667597
• Specific Activation of the G Protein-coupled Receptor BNGR-A21 by the Neuropeptide Corazonin from the Silkworm, Bombyx Mori, Dually Couples to the G(q) and G(s) Signaling Cascades
  The Journal of Biological Chemistry. Apr, 2013  |   Pubmed ID: 23457297
• Design, Synthesis and Biological Evaluation of Novel Piperazine Derivatives As CCR5 Antagonists
  PloS One. 2013  |   Pubmed ID: 23308267
• Identification and Characterization of Distinct C-terminal Domains of the Human Hydroxycarboxylic Acid Receptor-2 That Are Essential for Receptor Export, Constitutive Activity, Desensitization, and Internalization
  Molecular Pharmacology. Dec, 2012  |   Pubmed ID: 22962331
• Identification and Characterization of ZEL-H16 As a Novel Agonist of the Histamine H3 Receptor
  PloS One. 2012  |   Pubmed ID: 22870296
• An Update of Novel Screening Methods for GPCR in Drug Discovery
  Expert Opinion on Drug Discovery. Sep, 2012  |   Pubmed ID: 22716301
• Searching for the Multi-Target-Directed Ligands Against Alzheimer's Disease: Discovery of Quinoxaline-based Hybrid Compounds with AChE, H₃R and BACE 1 Inhibitory Activities
  Bioorganic & Medicinal Chemistry. Dec, 2011  |   Pubmed ID: 22019465
• Identification and Functional Characterization of Two Orphan G-protein-coupled Receptors for Adipokinetic Hormones from Silkworm Bombyx Mori
  The Journal of Biological Chemistry. Dec, 2011  |   Pubmed ID: 22009754
• Distinct Kinetic and Spatial Patterns of Protein Kinase C (PKC)- and Epidermal Growth Factor Receptor (EGFR)-dependent Activation of Extracellular Signal-regulated Kinases 1 and 2 by Human Nicotinic Acid Receptor GPR109A
  The Journal of Biological Chemistry. Sep, 2011  |   Pubmed ID: 21768093
• Development of a Novel DnaE Intein-based Assay for Quantitative Analysis of G-protein-coupled Receptor Internalization
  Analytical Biochemistry. Oct, 2011  |   Pubmed ID: 21726524
• Identification of Distinct C-terminal Domains of the Bombyx Adipokinetic Hormone Receptor That Are Essential for Receptor Export, Phosphorylation and Internalization
  Cellular Signalling. Sep, 2011  |   Pubmed ID: 21536126
• Identification and Characterization of INCB9471, an Allosteric Noncompetitive Small-molecule Antagonist of C-C Chemokine Receptor 5 with Potent Inhibitory Activity Against Monocyte Migration and HIV-1 Infection
  The Journal of Pharmacology and Experimental Therapeutics. Jul, 2011  |   Pubmed ID: 21459966
• Bombyx Adipokinetic Hormone Receptor Activates Extracellular Signal-regulated Kinase 1 and 2 Via G Protein-dependent PKA and PKC but β-arrestin-independent Pathways
  Biochemistry. Dec, 2010  |   Pubmed ID: 21126059
• Functional Characterization of a Naturally Occurring Trans-splicing Intein from Synechococcus Elongatus in a Mammalian Cell System
  Analytical Biochemistry. Dec, 2010  |   Pubmed ID: 20727340
• The G Protein-coupled Receptors in the Silkworm, Bombyx Mori
  Insect Biochemistry and Molecular Biology. Aug, 2010  |   Pubmed ID: 20685615
• Structural Optimization and Biological Evaluation of Substituted Bisphenol A Derivatives As Beta-amyloid Peptide Aggregation Inhibitors
  Journal of Medicinal Chemistry. Aug, 2010  |   Pubmed ID: 20684593
• Internalization of the Human Nicotinic Acid Receptor GPR109A is Regulated by G(i), GRK2, and Arrestin3
  The Journal of Biological Chemistry. Jul, 2010  |   Pubmed ID: 20460384
• An Enzyme-linked Immunosorbent Assay to Compare the Affinity of Chemical Compounds for β-amyloid Peptide As a Monomer
  Analytical and Bioanalytical Chemistry. Mar, 2010  |   Pubmed ID: 20135308
• Molecular and Functional Characterization of Adipokinetic Hormone Receptor and Its Peptide Ligands in Bombyx Mori
  FEBS Letters. May, 2009  |   Pubmed ID: 19345219
• A DEAD Box Protein Facilitates HIV-1 Replication As a Cellular Co-factor of Rev
  Virology. Dec, 2004  |   Pubmed ID: 15567440
• The N-terminal Domain of APJ, a CNS-based Coreceptor for HIV-1, is Essential for Its Receptor Function and Coreceptor Activity
  Virology. Dec, 2003  |   Pubmed ID: 14675627
• Structural and Functional Study of the Apelin-13 Peptide, an Endogenous Ligand of the HIV-1 Coreceptor, APJ
  Biochemistry. Sep, 2003  |   Pubmed ID: 12939143
• Binding of ALX40-4C to APJ, a CNS-based Receptor, Inhibits Its Utilization As a Co-receptor by HIV-1
  Virology. Jul, 2003  |   Pubmed ID: 12890632
• Cell-cell Fusion and Internalization of the CNS-based, HIV-1 Co-receptor, APJ
  Virology. Mar, 2003  |   Pubmed ID: 12667811
• Exploring the Stereochemistry of CXCR4-peptide Recognition and Inhibiting HIV-1 Entry with D-peptides Derived from Chemokines
  The Journal of Biological Chemistry. May, 2002  |   Pubmed ID: 11880384