Naoaki Ishii

Publications

• Long-term Administration of PDC Stimulative Lactic Acid Bacteria, Lactococcus Lactis Strain Plasma, Prevents Immune-senescence and Decelerates Individual Senescence
  Experimental Gerontology. Oct, 2018  |   Pubmed ID: 29964182
• Impaired P53/CEP-1 is Associated with Lifespan Extension Through an Age-related Imbalance in the Energy Metabolism of C. elegans
  Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Dec, 2017  |   Pubmed ID: 29114996
• Endogenous Reactive Oxygen Species Cause Astrocyte Defects and Neuronal Dysfunctions in the Hippocampus: a New Model for Aging Brain
  Aging Cell. Feb, 2017  |   Pubmed ID: 27623715
• Preparation of Clinically Useful Sennoside-reduced Rhubarb
  The Tokai Journal of Experimental and Clinical Medicine. Mar, 2016  |   Pubmed ID: 27050892
• Infertility and Recurrent Miscarriage with Complex II Deficiency-dependent Mitochondrial Oxidative Stress in Animal Models
  Mechanisms of Ageing and Development. Apr, 2016  |   Pubmed ID: 26944226
• A Combination of Mitochondrial Oxidative Stress and Excess Fat/Calorie Intake Accelerates Steatohepatitis by Enhancing Hepatic CC Chemokine Production in Mice
  PloS One. 2016  |   Pubmed ID: 26745268
• Association Between Insulin Resistance and Plasma Amino Acid Profile in Non-diabetic Japanese Subjects
  Journal of Diabetes Investigation. Jul, 2015  |   Pubmed ID: 26221519
• Ethyl Methanesulfonate Induces Mutations in Caenorhabditis Elegans Embryos at a High Frequency
  Mutation Research. Aug-Sep, 2014  |   Pubmed ID: 25847271
• Genetically Induced Oxidative Stress in Mice Causes Thrombocytosis, Splenomegaly and Placental Angiodysplasia That Leads to Recurrent Abortion
  Redox Biology. 2014  |   Pubmed ID: 24936442
• Haploinsufficiency of Akt1 Prolongs the Lifespan of Mice
  PloS One. 2013  |   Pubmed ID: 23935948
• Model Animals for the Study of Oxidative Stress from Complex II
  Biochimica Et Biophysica Acta. May, 2013  |   Pubmed ID: 23142169
• Oxidative Stress Induced Inflammation Initiates Functional Decline of Tear Production
  PloS One. 2012  |   Pubmed ID: 23071526
• Mitochondrial Superoxide Anion Overproduction in Tet-mev-1 Transgenic Mice Accelerates Age-dependent Corneal Cell Dysfunctions
  Investigative Ophthalmology & Visual Science. Aug, 2012  |   Pubmed ID: 22786907
• Mitochondrial Superoxide Anion (O(2)(-)) Inducible "mev-1" Animal Models for Aging Research
  BMB Reports. May, 2011  |   Pubmed ID: 21615983
• Interrelationships Between Mitochondrial Fusion, Energy Metabolism and Oxidative Stress During Development in Caenorhabditis Elegans
  Biochemical and Biophysical Research Communications. Jan, 2011  |   Pubmed ID: 21144829
• Mitochondrial Reactive Oxygen Species Generation by the SDHC V69E Mutation Causes Low Birth Weight and Neonatal Growth Retardation
  Mitochondrion. Jan, 2011  |   Pubmed ID: 20870041
• Post-dauer Life Span of Caenorhabditis Elegans Dauer Larvae Can Be Modified by X-irradiation
  Journal of Radiation Research. 2010  |   Pubmed ID: 19851044
• Beneficial Effects of Medical Advice Provided to Elderly Persons Under the Anti-aging Health Check-up System at Tokai University Tokyo Hospital
  The Tokai Journal of Experimental and Clinical Medicine. Dec, 2009  |   Pubmed ID: 21319015
• The Role of Mitochondrial Superoxide Anion (O2(-)) on Physiological Aging in C57BL/6J Mice
  Journal of Radiation Research. Jan, 2009  |   Pubmed ID: 19218782
• Cell Growth of the Mouse SDHC Mutant Cells Was Suppressed by Apoptosis Throughout Mitochondrial Pathway
  Bioscience Trends. Feb, 2008  |   Pubmed ID: 20103895
• Role of Oxidative Stress from Mitochondria on Aging and Cancer
  Cornea. Oct, 2007  |   Pubmed ID: 17881913
• Basic Principle of the Lifespan in the Nematode C. Elegans
  Mechanisms of Ageing and Development. Sep, 2007  |   Pubmed ID: 17707465
• The Role of the Electron Transport SDHC Gene on Lifespan and Cancer
  Mitochondrion. Feb-Apr, 2007  |   Pubmed ID: 17321223
• The Role of the Electron Transport Gene SDHC on Lifespan and Cancer
  Experimental Gerontology. Oct, 2006  |   Pubmed ID: 16962276
• Age-related Changes of Mitochondrial Structure and Function in Caenorhabditis Elegans
  Mechanisms of Ageing and Development. Oct, 2006  |   Pubmed ID: 16893561
• [Aging and Age-related Diseases Caused by Superoxide Anion Production from Mitochondria]
  Seikagaku. The Journal of Japanese Biochemical Society. Mar, 2006  |   Pubmed ID: 16634564
• [Why Do Peoples Age? the Mechanisms of Organismal Aging and Longevity]
  Nihon Shokakibyo Gakkai Zasshi = The Japanese Journal of Gastro-enterology. Feb, 2006  |   Pubmed ID: 16506661
• The Role of Stress in Ageing: Research on the Nematode, Caenorhabditis Elegans
  The British Journal of Dermatology. Dec, 2005  |   Pubmed ID: 16280015
• The P38 Signal Transduction Pathway Participates in the Oxidative Stress-mediated Translocation of DAF-16 to Caenorhabditis Elegans Nuclei
  Mechanisms of Ageing and Development. Jun-Jul, 2005  |   Pubmed ID: 15888317
• Effect of Oxidative Stress on Translocation of DAF-16 in Oxygen-sensitive Mutants, Mev-1 and Gas-1 of Caenorhabditis Elegans
  Mechanisms of Ageing and Development. Jun-Jul, 2005  |   Pubmed ID: 15888316
• Direct Measurement of Oxygen Consumption Rate on the Nematode Caenorhabditis Elegans by Using an Optical Technique
  Biochemical and Biophysical Research Communications. May, 2005  |   Pubmed ID: 15809072
• A Mutation in the SDHC Gene of Complex II Increases Oxidative Stress, Resulting in Apoptosis and Tumorigenesis
  Cancer Research. Jan, 2005  |   Pubmed ID: 15665296
• Coenzyme Q10 Can Prolong C. Elegans Lifespan by Lowering Oxidative Stress
  Mechanisms of Ageing and Development. Jan, 2004  |   Pubmed ID: 14706236
• A Complex II Defect Affects Mitochondrial Structure, Leading to Ced-3- and Ced-4-dependent Apoptosis and Aging
  The Journal of Biological Chemistry. Jun, 2003  |   Pubmed ID: 12672828
• VBP-1 is Necessary for Morphogenesis in Caenorhabditis Elegans
  Oncology Reports. Mar-Apr, 2003  |   Pubmed ID: 12579260
• Complex II Inactivation is Lethal in the Nematode Caenorhabditis Elegans
  Mitochondrion. Dec, 2002  |   Pubmed ID: 16120320
• Adaptive Responses to Oxidative Damage in Three Mutants of Caenorhabditis Elegans (age-1, Mev-1 and Daf-16) That Affect Life Span
  Mechanisms of Ageing and Development. Nov, 2002  |   Pubmed ID: 12470895
• Protein Oxidation During Aging of the Nematode Caenorhabditis Elegans
  Free Radical Biology & Medicine. Oct, 2002  |   Pubmed ID: 12374613
• [Mitochondrial Function and Aging]
  Nihon Rinsho. Japanese Journal of Clinical Medicine. Apr, 2002  |   Pubmed ID: 12013849
• Oxidative Stress and Aging in Caenorhabditis Elegans
  Free Radical Research. Dec, 2000  |   Pubmed ID: 11237107
• A Mutation in Succinate Dehydrogenase Cytochrome B Causes Oxidative Stress and Ageing in Nematodes
  Nature. Aug, 1998  |   Pubmed ID: 9716135
• Isolation and Genetic Analysis of Amber UvrA and UvrB Mutants
  Journal of Bacteriology. Apr, 1976  |   Pubmed ID: 770438