Natalie L. Trevaskis Drug Delivery, Disposition, and Dynamics, Monash Institute of Pharmaceutical Sciences Monash University (Parkville Campus) Biography Publications Institution JoVE Articles Natalie L. Trevaskis has not added a biography. If you are Natalie L. Trevaskis and would like to personalize this page please email our Author Liaison for assistance. Publications Methotrexate-conjugated PEGylated Dendrimers Show Differential Patterns of Deposition and Activity in Tumour-burdened Lymph Nodes After Intravenous and Subcutaneous Administration in Rats Molecular Pharmaceutics. Dec, 2014 | Pubmed ID: 25485615 Profiling the Role of Deacylation-Reacylation in the Lymphatic Transport of a Triglyceride-Mimetic Prodrug Pharmaceutical Research. Dec, 2014 | Pubmed ID: 25446770 In Vitro-in Vivo Evaluation of Lipid Based Formulations of the CETP Inhibitors CP-529,414 (torcetrapib) and CP-532,623 European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V. Nov, 2014 | Pubmed ID: 25152213 Targeted Delivery of a Model Immunomodulator to the Lymphatic System: Comparison of Alkyl Ester Versus Triglyceride Mimetic Lipid Prodrug Strategies Journal of Controlled Release : Official Journal of the Controlled Release Society. Mar, 2014 | Pubmed ID: 24398334 Recent Advances in Lipid-based Formulation Technology Pharmaceutical Research. Dec, 2013 | Pubmed ID: 24158727 Lipid-based Formulations and Drug Supersaturation: Harnessing the Unique Benefits of the Lipid Digestion/absorption Pathway Pharmaceutical Research. Dec, 2013 | Pubmed ID: 23824582 Lipid Absorption Triggers Drug Supersaturation at the Intestinal Unstirred Water Layer and Promotes Drug Absorption from Mixed Micelles Pharmaceutical Research. Dec, 2013 | Pubmed ID: 23793990 The Potential for Drug Supersaturation During Intestinal Processing of Lipid-based Formulations May Be Enhanced for Basic Drugs Molecular Pharmaceutics. Jul, 2013 | Pubmed ID: 23697606 The Impact of Lymphatic Transport on the Systemic Disposition of Lipophilic Drugs Journal of Pharmaceutical Sciences. Jul, 2013 | Pubmed ID: 23696002 Intestinal Bile Secretion Promotes Drug Absorption from Lipid Colloidal Phases Via Induction of Supersaturation Molecular Pharmaceutics. May, 2013 | Pubmed ID: 23480483 A Mouse Model to Evaluate the Impact of Species, Sex, and Lipid Load on Lymphatic Drug Transport Pharmaceutical Research. Dec, 2013 | Pubmed ID: 23430484 Strategies to Address Low Drug Solubility in Discovery and Development Pharmacological Reviews. Jan, 2013 | Pubmed ID: 23383426 Intravenous Dosing Conditions May Affect Systemic Clearance for Highly Lipophilic Drugs: Implications for Lymphatic Transport and Absolute Bioavailability Studies Journal of Pharmaceutical Sciences. Sep, 2012 | Pubmed ID: 22623170 Correction to "targeted Drug Delivery to Lymphocytes: a Route to Site-specific Immunomodulation?" Molecular Pharmaceutics. Dec, 2011 | Pubmed ID: 21995681 Acute Hypertriglyceridemia Promotes Intestinal Lymphatic Lipid and Drug Transport: a Positive Feedback Mechanism in Lipid and Drug Absorption Molecular Pharmaceutics. Aug, 2011 | Pubmed ID: 21604764 Fatty Acid Binding Proteins: Potential Chaperones of Cytosolic Drug Transport in the Enterocyte? Pharmaceutical Research. Sep, 2011 | Pubmed ID: 21523511 Targeted Drug Delivery to Lymphocytes: a Route to Site-specific Immunomodulation? Molecular Pharmaceutics. Dec, 2010 | Pubmed ID: 20958081 The Mechanism of Lymphatic Access of Two Cholesteryl Ester Transfer Protein Inhibitors (CP524,515 and CP532,623) and Evaluation of Their Impact on Lymph Lipoprotein Profiles Pharmaceutical Research. Sep, 2010 | Pubmed ID: 20635194 The Role of the Intestinal Lymphatics in the Absorption of Two Highly Lipophilic Cholesterol Ester Transfer Protein Inhibitors (CP524,515 and CP532,623) Pharmaceutical Research. May, 2010 | Pubmed ID: 20221896 Intestinal Lymphatic Transport Enhances the Post-prandial Oral Bioavailability of a Novel Cannabinoid Receptor Agonist Via Avoidance of First-pass Metabolism Pharmaceutical Research. Jun, 2009 | Pubmed ID: 19280324 Lipid-based Delivery Systems and Intestinal Lymphatic Drug Transport: a Mechanistic Update Advanced Drug Delivery Reviews. Mar, 2008 | Pubmed ID: 18155316 Lipids and Lipid-based Formulations: Optimizing the Oral Delivery of Lipophilic Drugs Nature Reviews. Drug Discovery. Mar, 2007 | Pubmed ID: 17330072 An Acute and Coincident Increase in FABP Expression and Lymphatic Lipid and Drug Transport Occurs During Intestinal Infusion of Lipid-based Drug Formulations to Rats Pharmaceutical Research. Aug, 2006 | Pubmed ID: 16858652 An Examination of the Interplay Between Enterocyte-based Metabolism and Lymphatic Drug Transport in the Rat Drug Metabolism and Disposition: the Biological Fate of Chemicals. May, 2006 | Pubmed ID: 16467133 The Lymph Lipid Precursor Pool is a Key Determinant of Intestinal Lymphatic Drug Transport The Journal of Pharmacology and Experimental Therapeutics. Feb, 2006 | Pubmed ID: 16249368 Tissue Uptake of DDT is Independent of Chylomicron Metabolism Archives of Toxicology. Apr, 2006 | Pubmed ID: 16180009 Bile Increases Intestinal Lymphatic Drug Transport in the Fasted Rat Pharmaceutical Research. Nov, 2005 | Pubmed ID: 16132351 A linfa mesentérica Duct canulada Rat Modelo: Aplicação para a Avaliação de Intestinal Linfática transporte da droga Natalie L. Trevaskis1, Luojuan Hu1, Suzanne M. Caliph1, Sifei Han1, Christopher J.H. Porter1 1Drug Delivery, Disposition, and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus) Immunology and Infection
A linfa mesentérica Duct canulada Rat Modelo: Aplicação para a Avaliação de Intestinal Linfática transporte da droga Natalie L. Trevaskis1, Luojuan Hu1, Suzanne M. Caliph1, Sifei Han1, Christopher J.H. Porter1 1Drug Delivery, Disposition, and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus) Immunology and Infection