Nathan N. Alder Department of Molecular and Cell Biology University of Connecticut Biography Publications Institution JoVE Articles Nathan N. Alder has not added a biography. If you are Nathan N. Alder and would like to personalize this page please email our Author Liaison for assistance. Publications Conserved Cardiolipin-mitochondrial ADP/ATP Carrier Interactions Assume Distinct Structural and Functional Roles That Are Clinically Relevant BioRxiv : the Preprint Server for Biology. May, 2023 | Pubmed ID: 37205478 Depicting Protein Structures As Schematics Trends in Biochemical Sciences. Apr, 2023 | Pubmed ID: 36931235 Associations of Mitochondrial Function, Stress, and Neurodevelopmental Outcomes in Early Life: A Systematic Review Developmental Neuroscience. 2022 | Pubmed ID: 35995037 Structure-activity Relationships of Mitochondria-targeted Tetrapeptide Pharmacological Compounds ELife. Aug, 2022 | Pubmed ID: 35913044 Mitochondrial Compartmentalization: Emerging Themes in Structure and Function Trends in Biochemical Sciences. Nov, 2021 | Pubmed ID: 34244035 Reduction of Elevated Proton Leak Rejuvenates Mitochondria in the Aged Cardiomyocyte ELife. Dec, 2020 | Pubmed ID: 33319746 The Mitochondria-targeted Peptide SS-31 Binds Lipid Bilayers and Modulates Surface Electrostatics As a Key Component of Its Mechanism of Action The Journal of Biological Chemistry. May, 2020 | Pubmed ID: 32273339 Phosphatidylethanolamine Made in the Inner Mitochondrial Membrane is Essential for Yeast Cytochrome Bc Complex Function Nature Communications. Mar, 2019 | Pubmed ID: 30926815 Molecular Dynamics Analysis of Cardiolipin and Monolysocardiolipin on Bilayer Properties Biophysical Journal. May, 2018 | Pubmed ID: 29742405 Cardiolipin Mediates Membrane and Channel Interactions of the Mitochondrial TIM23 Protein Import Complex Receptor Tim50 Science Advances. Sep, 2017 | Pubmed ID: 28879236 Buckling Under Pressure: Curvature-Based Lipid Segregation and Stability Modulation in Cardiolipin-Containing Bilayers Langmuir : the ACS Journal of Surfaces and Colloids. Jul, 2017 | Pubmed ID: 28628337 Reconstitution of Mitochondrial Membrane Proteins into Nanodiscs by Cell-Free Expression Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 28276018 Ionization Properties of Phospholipids Determined by Zeta Potential Measurements Bio-protocol. Nov, 2016 | Pubmed ID: 27928550 The Ionization Properties of Cardiolipin and Its Variants in Model Bilayers Biochimica Et Biophysica Acta. Jun, 2016 | Pubmed ID: 26965987 Targeting Mitochondria with Methylene Blue Protects Mice Against Acetaminophen-induced Liver Injury Hepatology (Baltimore, Md.). Jan, 2015 | Pubmed ID: 25142022 Advances in the Use of Nanoscale Bilayers to Study Membrane Protein Structure and Function Biotechnology & Genetic Engineering Reviews. Oct, 2014 | Pubmed ID: 25023464 Unremodeled and Remodeled Cardiolipin Are Functionally Indistinguishable in Yeast The Journal of Biological Chemistry. Jan, 2014 | Pubmed ID: 24285538 Site-specific Fluorescent Probe Labeling of Mitochondrial Membrane Proteins Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23996173 Isoniazid-induced Cell Death is Precipitated by Underlying Mitochondrial Complex I Dysfunction in Mouse Hepatocytes Free Radical Biology & Medicine. Jul, 2013 | Pubmed ID: 23911619 Structural Changes in the Mitochondrial Tim23 Channel Are Coupled to the Proton-motive Force Nature Structural & Molecular Biology. Aug, 2013 | Pubmed ID: 23832274 A Detergent-free Strategy for the Reconstitution of Active Enzyme Complexes from Native Biological Membranes into Nanoscale Discs BMC Biotechnology. May, 2013 | Pubmed ID: 23663692 The Cell-free Integration of a Polytopic Mitochondrial Membrane Protein into Liposomes Occurs Cotranslationally and in a Lipid-dependent Manner PloS One. 2012 | Pubmed ID: 23050015 The Stability and Activity of Respiratory Complex II is Cardiolipin-dependent Biochimica Et Biophysica Acta. Sep, 2012 | Pubmed ID: 22575443 Green Proteorhodopsin Reconstituted into Nanoscale Phospholipid Bilayers (nanodiscs) As Photoactive Monomers Journal of the American Chemical Society. Nov, 2011 | Pubmed ID: 21951206 Mechanism of Amylin Fibrillization Enhancement by Heparin The Journal of Biological Chemistry. Jul, 2011 | Pubmed ID: 21555785 Decoding Mitochondrial Aging (Video) | JoVE Emery L. Ng1, Ashley L. Reed2, Christopher B. O’Connell1, Nathan N. Alder2 1Center for Open Research Resources and Equipment, University of Connecticut, 2Department of Molecular and Cell Biology, University of Connecticut JoVE 65561 Neuroscience
Decoding Mitochondrial Aging (Video) | JoVE Emery L. Ng1, Ashley L. Reed2, Christopher B. O’Connell1, Nathan N. Alder2 1Center for Open Research Resources and Equipment, University of Connecticut, 2Department of Molecular and Cell Biology, University of Connecticut JoVE 65561 Neuroscience