Neil A.R. Gow Aberdeen Fungal Group University of Aberdeen Biography Publications Institution JoVE Articles Neil A.R. Gow has not added a biography. If you are Neil A.R. Gow and would like to personalize this page please email our Author Liaison for assistance. Publications Elevated Chitin Content Reduces the Susceptibility of Candida Species to Caspofungin Antimicrobial Agents and Chemotherapy. Jan, 2013 | Pubmed ID: 23089748 Hidden Killers: Human Fungal Infections Science Translational Medicine. Dec, 2012 | Pubmed ID: 23253612 The Evolutionary Rewiring of Ubiquitination Targets Has Reprogrammed the Regulation of Carbon Assimilation in the Pathogenic Yeast Candida Albicans MBio. 2012 | Pubmed ID: 23232717 Identification of Vacuole Defects in Fungi Journal of Microbiological Methods. Oct, 2012 | Pubmed ID: 22902527 Candida Albicans Infection Inhibits Macrophage Cell Division and Proliferation Fungal Genetics and Biology : FG & B. Sep, 2012 | Pubmed ID: 22634272 A Systems Biology Analysis of Long and Short-term Memories of Osmotic Stress Adaptation in Fungi BMC Research Notes. 2012 | Pubmed ID: 22631601 Importance of the Candida Albicans Cell Wall During Commensalism and Infection Current Opinion in Microbiology. Aug, 2012 | Pubmed ID: 22609181 Host Carbon Sources Modulate Cell Wall Architecture, Drug Resistance and Virulence in a Fungal Pathogen Cellular Microbiology. Sep, 2012 | Pubmed ID: 22587014 β(1,3)-glucan Synthase Complex from Alternaria Infectoria, a Rare Dematiaceous Human Pathogen Medical Mycology : Official Publication of the International Society for Human and Animal Mycology. Oct, 2012 | Pubmed ID: 22548239 Combinatorial Stresses Kill Pathogenic Candida Species Medical Mycology : Official Publication of the International Society for Human and Animal Mycology. Oct, 2012 | Pubmed ID: 22463109 Stage Specific Assessment of Candida Albicans Phagocytosis by Macrophages Identifies Cell Wall Composition and Morphogenesis As Key Determinants PLoS Pathogens. 2012 | Pubmed ID: 22438806 Murine Bone Marrow-derived Dendritic Cells and T-cell Activation by Candida Albicans Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22328380 Interactions Between Macrophages and Cell Wall Oligosaccharides of Candida Albicans Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22328379 Biochemical Characterization of Recombinant Candida Albicans Mannosyltransferases Mnt1, Mnt2 and Mnt5 Reveals New Functions in O- and N-mannan Biosynthesis Biochemical and Biophysical Research Communications. Mar, 2012 | Pubmed ID: 22326920 Non-lytic Expulsion/exocytosis of Candida Albicans from Macrophages Fungal Genetics and Biology : FG & B. Sep, 2012 | Pubmed ID: 22326419 Candida Albicans Morphogenesis and Host Defence: Discriminating Invasion from Colonization Nature Reviews. Microbiology. Feb, 2012 | Pubmed ID: 22158429 Elevated Cell Wall Chitin in Candida Albicans Confers Echinocandin Resistance in Vivo Antimicrobial Agents and Chemotherapy. Jan, 2012 | Pubmed ID: 21986821 Candida Albicans Cell Wall Glycosylation May Be Indirectly Required for Activation of Epithelial Cell Proinflammatory Responses Infection and Immunity. Dec, 2011 | Pubmed ID: 21930756 Wild-type Drosophila Melanogaster As an Alternative Model System for Investigating the Pathogenicity of Candida Albicans Disease Models & Mechanisms. Jul, 2011 | Pubmed ID: 21540241 The Dectin-1/inflammasome Pathway is Responsible for the Induction of Protective T-helper 17 Responses That Discriminate Between Yeasts and Hyphae of Candida Albicans Journal of Leukocyte Biology. Aug, 2011 | Pubmed ID: 21531876 Recognition and Blocking of Innate Immunity Cells by Candida Albicans Chitin Infection and Immunity. May, 2011 | Pubmed ID: 21357722 Nitric Oxide and Nitrosative Stress Tolerance in Yeast Biochemical Society Transactions. Jan, 2011 | Pubmed ID: 21265777 Glycosylation Status of the C. Albicans Cell Wall Affects the Efficiency of Neutrophil Phagocytosis and Killing but Not Cytokine Signaling Medical Mycology : Official Publication of the International Society for Human and Animal Mycology. Jul, 2011 | Pubmed ID: 21254968 Fig1 Facilitates Calcium Influx and Localizes to Membranes Destined to Undergo Fusion During Mating in Candida Albicans Eukaryotic Cell. Mar, 2011 | Pubmed ID: 21216943 Differential Regulation of Kidney and Spleen Cytokine Responses in Mice Challenged with Pathology-standardized Doses of Candida Albicans Mannosylation Mutants Infection and Immunity. Jan, 2011 | Pubmed ID: 21059878 CO(2) Acts As a Signalling Molecule in Populations of the Fungal Pathogen Candida Albicans PLoS Pathogens. 2010 | Pubmed ID: 21124988 Chitin Synthesis and Fungal Pathogenesis Current Opinion in Microbiology. Aug, 2010 | Pubmed ID: 20561815 Melanin Externalization in Candida Albicans Depends on Cell Wall Chitin Structures Eukaryotic Cell. Sep, 2010 | Pubmed ID: 20543065 Phosphorylation Regulates Polarisation of Chitin Synthesis in Candida Albicans Journal of Cell Science. Jul, 2010 | Pubmed ID: 20530569 Variable Recognition of Candida Albicans Strains by TLR4 and Lectin Recognition Receptors Medical Mycology : Official Publication of the International Society for Human and Animal Mycology. Nov, 2010 | Pubmed ID: 20166865 A Multifunctional Mannosyltransferase Family in Candida Albicans Determines Cell Wall Mannan Structure and Host-fungus Interactions The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20164191 Pseudomonas Aeruginosa Secreted Factors Impair Biofilm Development in Candida Albicans Microbiology (Reading, England). May, 2010 | Pubmed ID: 20150241 Fungal Echinocandin Resistance Fungal Genetics and Biology : FG & B. Feb, 2010 | Pubmed ID: 19770064 Glucose Promotes Stress Resistance in the Fungal Pathogen Candida Albicans Molecular Biology of the Cell. Nov, 2009 | Pubmed ID: 19759180 Comparative Genomics of the Fungal Pathogens Candida Dubliniensis and Candida Albicans Genome Research. Dec, 2009 | Pubmed ID: 19745113 Early-expressed Chemokines Predict Kidney Immunopathology in Experimental Disseminated Candida Albicans Infections PloS One. 2009 | Pubmed ID: 19641609 Comparative Genomics of MAP Kinase and Calcium-calcineurin Signalling Components in Plant and Human Pathogenic Fungi Fungal Genetics and Biology : FG & B. Apr, 2009 | Pubmed ID: 19570501 Mechanisms of Hypha Orientation of Fungi Current Opinion in Microbiology. Aug, 2009 | Pubmed ID: 19546023 Evolution of Pathogenicity and Sexual Reproduction in Eight Candida Genomes Nature. Jun, 2009 | Pubmed ID: 19465905 Toll-like Receptor 9-dependent Activation of Myeloid Dendritic Cells by Deoxynucleic Acids from Candida Albicans Infection and Immunity. Jul, 2009 | Pubmed ID: 19433551 Fungal Morphogenesis: Some Like It Hot Current Biology : CB. Apr, 2009 | Pubmed ID: 19409283 Pseudohypha Budding Patterns of Candida Albicans Medical Mycology : Official Publication of the International Society for Human and Animal Mycology. May, 2009 | Pubmed ID: 19347739 Loss of Mannosylphosphate from Candida Albicans Cell Wall Proteins Results in Enhanced Resistance to the Inhibitory Effect of a Cationic Antimicrobial Peptide Via Reduced Peptide Binding to the Cell Surface Microbiology (Reading, England). Apr, 2009 | Pubmed ID: 19332808 Pattern Recognition: Recent Insights from Dectin-1 Current Opinion in Immunology. Feb, 2009 | Pubmed ID: 19223162 Bypassing Pathogen-induced Inflammasome Activation for the Regulation of Interleukin-1beta Production by the Fungal Pathogen Candida Albicans The Journal of Infectious Diseases. Apr, 2009 | Pubmed ID: 19222370 Candida Albicans ABG1 Gene is Involved in Endocytosis FEMS Yeast Research. Mar, 2009 | Pubmed ID: 19175413 Proteomic and Phenotypic Profiling of the Amphibian Pathogen Batrachochytrium Dendrobatidis Shows That Genotype is Linked to Virulence Molecular Ecology. Feb, 2009 | Pubmed ID: 19161465 Calcium Homeostasis is Required for Contact-dependent Helical and Sinusoidal Tip Growth in Candida Albicans Hyphae Molecular Microbiology. Mar, 2009 | Pubmed ID: 19154328 Dissection of the Candida Albicans Class I Chitin Synthase Promoters Molecular Genetics and Genomics : MGG. Apr, 2009 | Pubmed ID: 19153767 Property Differences Among the Four Major Candida Albicans Strain Clades Eukaryotic Cell. Mar, 2009 | Pubmed ID: 19151328 Vacuole Inheritance Regulates Cell Size and Branching Frequency of Candida Albicans Hyphae Molecular Microbiology. Jan, 2009 | Pubmed ID: 19040629 Genome-wide Analysis of Candida Albicans Gene Expression Patterns During Infection of the Mammalian Kidney Fungal Genetics and Biology : FG & B. Feb, 2009 | Pubmed ID: 19032986 Vacuolar Dynamics During the Morphogenetic Transition in Candida Albicans FEMS Yeast Research. Dec, 2008 | Pubmed ID: 19054134 Kex2 Protease Converts the Endoplasmic Reticulum Alpha1,2-mannosidase of Candida Albicans into a Soluble Cytosolic Form Microbiology (Reading, England). Dec, 2008 | Pubmed ID: 19047746 Vacuoles and Fungal Biology Current Opinion in Microbiology. Dec, 2008 | Pubmed ID: 18935977 Mixed Candida Albicans Strain Populations in Colonized and Infected Mucosal Tissues FEMS Yeast Research. Dec, 2008 | Pubmed ID: 18795958 Functional Analysis of Candida Albicans GPI-anchored Proteins: Roles in Cell Wall Integrity and Caspofungin Sensitivity Fungal Genetics and Biology : FG & B. Oct, 2008 | Pubmed ID: 18765290 Cell Wall Glycans and Soluble Factors Determine the Interactions Between the Hyphae of Candida Albicans and Pseudomonas Aeruginosa FEMS Microbiology Letters. Oct, 2008 | Pubmed ID: 18680523 Mitochondrial Haplotypes and Recombination in Candida Albicans Medical Mycology : Official Publication of the International Society for Human and Animal Mycology. Nov, 2008 | Pubmed ID: 18608923 Host-microbe Interactions: Innate Pattern Recognition of Fungal Pathogens Current Opinion in Microbiology. Aug, 2008 | Pubmed ID: 18602019 Dendritic Cell Interaction with Candida Albicans Critically Depends on N-linked Mannan The Journal of Biological Chemistry. Jul, 2008 | Pubmed ID: 18482990 Internuclear Gene Silencing in Phytophthora Infestans is Established Through Chromatin Remodelling Microbiology (Reading, England). May, 2008 | Pubmed ID: 18451057 Molecular Phylogenetic Analysis of Candida Tropicalis Isolates by Multi-locus Sequence Typing Fungal Genetics and Biology : FG & B. Jun, 2008 | Pubmed ID: 18440253 Stimulation of Chitin Synthesis Rescues Candida Albicans from Echinocandins PLoS Pathogens. Apr, 2008 | Pubmed ID: 18389063 An Internal Polarity Landmark is Important for Externally Induced Hyphal Behaviors in Candida Albicans Eukaryotic Cell. Apr, 2008 | Pubmed ID: 18281602 Syk Kinase is Required for Collaborative Cytokine Production Induced Through Dectin-1 and Toll-like Receptors European Journal of Immunology. Feb, 2008 | Pubmed ID: 18200499 Comparison of Candida Albicans Strain Types Among Isolates from Three Countries International Journal of Medical Microbiology : IJMM. Oct, 2008 | Pubmed ID: 18165151 An Integrated Model of the Recognition of Candida Albicans by the Innate Immune System Nature Reviews. Microbiology. Jan, 2008 | Pubmed ID: 18079743 Azole Antifungals Induce Up-regulation of SAP4, SAP5 and SAP6 Secreted Proteinase Genes in Filamentous Candida Albicans Cells in Vitro and in Vivo The Journal of Antimicrobial Chemotherapy. Feb, 2008 | Pubmed ID: 18033783 Immune Recognition of Candida Albicans Beta-glucan by Dectin-1 The Journal of Infectious Diseases. Nov, 2007 | Pubmed ID: 18008237 Individual Chitin Synthase Enzymes Synthesize Microfibrils of Differing Structure at Specific Locations in the Candida Albicans Cell Wall Molecular Microbiology. Dec, 2007 | Pubmed ID: 17971081 Endoplasmic Reticulum Alpha-glycosidases of Candida Albicans Are Required for N Glycosylation, Cell Wall Integrity, and Normal Host-fungus Interaction Eukaryotic Cell. Dec, 2007 | Pubmed ID: 17933909 Infection-related Gene Expression in Candida Albicans Current Opinion in Microbiology. Aug, 2007 | Pubmed ID: 17707687 One Year Prospective Survey of Candida Bloodstream Infections in Scotland Journal of Medical Microbiology. Aug, 2007 | Pubmed ID: 17644714 Molecular Phylogenetics of Candida Albicans Eukaryotic Cell. Jun, 2007 | Pubmed ID: 17416899 Candida Albicans Iff11, a Secreted Protein Required for Cell Wall Structure and Virulence Infection and Immunity. Jun, 2007 | Pubmed ID: 17371861 The PKC, HOG and Ca2+ Signalling Pathways Co-ordinately Regulate Chitin Synthesis in Candida Albicans Molecular Microbiology. Mar, 2007 | Pubmed ID: 17302816 Developmental Regulation of an Adhesin Gene During Cellular Morphogenesis in the Fungal Pathogen Candida Albicans Eukaryotic Cell. Apr, 2007 | Pubmed ID: 17277173 Hyphal Orientation of Candida Albicans is Regulated by a Calcium-dependent Mechanism Current Biology : CB. Feb, 2007 | Pubmed ID: 17275302 Strain Typing and Determination of Population Structure of Candida Krusei by Multilocus Sequence Typing Journal of Clinical Microbiology. Feb, 2007 | Pubmed ID: 17122025 Immune Sensing of Candida Albicans Requires Cooperative Recognition of Mannans and Glucans by Lectin and Toll-like Receptors The Journal of Clinical Investigation. Jun, 2006 | Pubmed ID: 16710478 Niche-specific Regulation of Central Metabolic Pathways in a Fungal Pathogen Cellular Microbiology. Jun, 2006 | Pubmed ID: 16681837 Candida Albicans VAC8 is Required for Vacuolar Inheritance and Normal Hyphal Branching Eukaryotic Cell. Feb, 2006 | Pubmed ID: 16467476 Outer Chain N-glycans Are Required for Cell Wall Integrity and Virulence of Candida Albicans The Journal of Biological Chemistry. Jan, 2006 | Pubmed ID: 16263704 Population Structure and Properties of Candida Albicans, As Determined by Multilocus Sequence Typing Journal of Clinical Microbiology. Nov, 2005 | Pubmed ID: 16272493 Multilocus Sequence Typing for Differentiation of Strains of Candida Tropicalis Journal of Clinical Microbiology. Nov, 2005 | Pubmed ID: 16272492 Global Role of the Protein Kinase Gcn2 in the Human Pathogen Candida Albicans Eukaryotic Cell. Oct, 2005 | Pubmed ID: 16215176 Fungal Genomics: Forensic Evidence of Sexual Activity Current Biology : CB. Jul, 2005 | Pubmed ID: 16005285 ABG1, a Novel and Essential Candida Albicans Gene Encoding a Vacuolar Protein Involved in Cytokinesis and Hyphal Branching Eukaryotic Cell. Jun, 2005 | Pubmed ID: 15947201 Candida Albicans Pmr1p, a Secretory Pathway P-type Ca2+/Mn2+-ATPase, is Required for Glycosylation and Virulence The Journal of Biological Chemistry. Jun, 2005 | Pubmed ID: 15843378 Exposure of Candida Albicans to Antifungal Agents Affects Expression of SAP2 and SAP9 Secreted Proteinase Genes The Journal of Antimicrobial Chemotherapy. May, 2005 | Pubmed ID: 15820985 Potassium Homeostasis Influences the Locomotion and Encystment of Zoospores of Plant Pathogenic Oomycetes Fungal Genetics and Biology : FG & B. Mar, 2005 | Pubmed ID: 15707842 Candida Orthopsilosis and Candida Metapsilosis Spp. Nov. to Replace Candida Parapsilosis Groups II and III Journal of Clinical Microbiology. Jan, 2005 | Pubmed ID: 15634984 Mnt1p and Mnt2p of Candida Albicans Are Partially Redundant Alpha-1,2-mannosyltransferases That Participate in O-linked Mannosylation and Are Required for Adhesion and Virulence The Journal of Biological Chemistry. Jan, 2005 | Pubmed ID: 15519997 Candida Albicans Mutants in the BNI4 Gene Have Reduced Cell-wall Chitin and Alterations in Morphogenesis Microbiology (Reading, England). Oct, 2004 | Pubmed ID: 15470104 Homologous Recombination in Candida Albicans: Role of CaRad52p in DNA Repair, Integration of Linear DNA Fragments and Telomere Length Molecular Microbiology. Aug, 2004 | Pubmed ID: 15306020 Ectopic Expression of URA3 Can Influence the Virulence Phenotypes and Proteome of Candida Albicans but Can Be Overcome by Targeted Reintegration of URA3 at the RPS10 Locus Eukaryotic Cell. Aug, 2004 | Pubmed ID: 15302823 The Candida Albicans PH-regulated KER1 Gene Encodes a Lysine/glutamic-acid-rich Plasma-membrane Protein That is Involved in Cell Aggregation Microbiology (Reading, England). Aug, 2004 | Pubmed ID: 15289560 Loss of Cell Wall Mannosylphosphate in Candida Albicans Does Not Influence Macrophage Recognition The Journal of Biological Chemistry. Sep, 2004 | Pubmed ID: 15271989 Candida Albicans Genome Sequence: a Platform for Genomics in the Absence of Genetics Genome Biology. 2004 | Pubmed ID: 15239821 Independent Regulation of Chitin Synthase and Chitinase Activity in Candida Albicans and Saccharomyces Cerevisiae Microbiology (Reading, England). Apr, 2004 | Pubmed ID: 15073301 Genetic Evidence for Recombination in Candida Albicans Based on Haplotype Analysis Fungal Genetics and Biology : FG & B. May, 2004 | Pubmed ID: 15050544 GFP As a Quantitative Reporter of Gene Regulation in Candida Albicans Yeast (Chichester, England). Mar, 2004 | Pubmed ID: 15042593 New Angles in Mycology: Studies in Directional Growth and Directional Motility Mycological Research. Jan, 2004 | Pubmed ID: 15035500 CHS8-a Fourth Chitin Synthase Gene of Candida Albicans Contributes to in Vitro Chitin Synthase Activity, but is Dispensable for Growth Fungal Genetics and Biology : FG & B. Nov, 2003 | Pubmed ID: 14516767 Optimization and Validation of Multilocus Sequence Typing for Candida Albicans Journal of Clinical Microbiology. Aug, 2003 | Pubmed ID: 12904388 EST Mining and Functional Expression Assays Identify Extracellular Effector Proteins from the Plant Pathogen Phytophthora Genome Research. Jul, 2003 | Pubmed ID: 12840044 Proteomic Analysis of Asexual Development of Phytophthora Palmivora Mycological Research. Apr, 2003 | Pubmed ID: 12825510 Antifungal Agents: Mechanisms of Action Trends in Microbiology. Jun, 2003 | Pubmed ID: 12823944 Asynchronous Cell Cycle and Asymmetric Vacuolar Inheritance in True Hyphae of Candida Albicans Eukaryotic Cell. Jun, 2003 | Pubmed ID: 12796285 Candida Albicans Binds Human Plasminogen: Identification of Eight Plasminogen-binding Proteins Molecular Microbiology. Mar, 2003 | Pubmed ID: 12622818 Candida Albicans Switches Mates Molecular Cell. Aug, 2002 | Pubmed ID: 12191464 Fungal Morphogenesis and Host Invasion Current Opinion in Microbiology. Aug, 2002 | Pubmed ID: 12160854 The Zygomycetous Fungus, Benjaminiella Poitrasii Contains a Large Family of Differentially Regulated Chitin Synthase Genes Fungal Genetics and Biology : FG & B. Aug, 2002 | Pubmed ID: 12135577 लाइव सेल कवक रोगज़नक़ phagocytosis के वीडियो माइक्रोस्कोपी Leanne E. Lewis1, Judith M. Bain1, Blessing Okai1, Neil A.R. Gow2, Lars Peter Erwig1,2 1Division of Applied Medicine, University of Aberdeen, 2Aberdeen Fungal Group, University of Aberdeen JoVE 50196 Immunology and Infection
लाइव सेल कवक रोगज़नक़ phagocytosis के वीडियो माइक्रोस्कोपी Leanne E. Lewis1, Judith M. Bain1, Blessing Okai1, Neil A.R. Gow2, Lars Peter Erwig1,2 1Division of Applied Medicine, University of Aberdeen, 2Aberdeen Fungal Group, University of Aberdeen JoVE 50196 Immunology and Infection