Neil Spratt School of Biomedical Sciences and Pharmacy University of Newcastle Biography Publications Institution JoVE Articles Neil Spratt has not added a biography. If you are Neil Spratt and would like to personalize this page please email our Author Liaison for assistance. Publications Role of Computed Tomography Perfusion in Identification of Acute Lacunar Stroke Syndromes Stroke. Jan, 2021 | Pubmed ID: 33370180 Association of Collateral Status and Ischemic Core Growth in Patients With Acute Ischemic Stroke Neurology. 01, 2021 | Pubmed ID: 33262233 What Is the "Optimal" Target Mismatch Criteria for Acute Ischemic Stroke? Frontiers in Neurology. 2020 | Pubmed ID: 33584495 Reduced Impact of Endovascular Thrombectomy on Disability in Real-World Practice, Relative to Randomized Controlled Trial Evidence in Australia Frontiers in Neurology. 2020 | Pubmed ID: 33363508 Multimodal Computed Tomography Increases the Detection of Posterior Fossa Strokes Compared to Brain Non-contrast Computed Tomography Frontiers in Neurology. 2020 | Pubmed ID: 33329332 An Online Survey of Informal Caregivers' Unmet Needs and Associated Factors PloS One. 2020 | Pubmed ID: 33301483 Plasmin Generation Potential and Recanalization in Acute Ischaemic Stroke; an Observational Cohort Study of Stroke Biobank Samples Frontiers in Neurology. 2020 | Pubmed ID: 33224099 Tranexamic Acid in Patients with Intracerebral Haemorrhage (STOP-AUST): a Multicentre, Randomised, Placebo-controlled, Phase 2 Trial The Lancet. Neurology. 12, 2020 | Pubmed ID: 33128912 Exploring the Economic Benefits of Modafinil for Post-Stroke Fatigue in Australia: A Cost-Effectiveness Evaluation Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. Nov, 2020 | Pubmed ID: 33066879 Air Vs. Road Decision for Endovascular Clot Retrieval in a Rural Telestroke Network Frontiers in Neurology. 2020 | Pubmed ID: 32765396 The Characteristics of Patients With Possible Transient Ischemic Attack and Minor Stroke in the Hunter and Manning Valley Regions, Australia (the INSIST Study) Frontiers in Neurology. 2020 | Pubmed ID: 32670173 Permeability Measures Predict Hemorrhagic Transformation After Ischemic Stroke Annals of Neurology. 09, 2020 | Pubmed ID: 32418242 The Long-term Unmet Needs of Informal Carers of Stroke Survivors at Home: a Systematic Review of Qualitative and Quantitative Studies Disability and Rehabilitation. May, 2020 | Pubmed ID: 32393074 No Evidence of the "Weekend Effect" in the Northern New South Wales Telestroke Network Frontiers in Neurology. 2020 | Pubmed ID: 32174885 Perfusion Computed Tomography Accurately Quantifies Collateral Flow After Acute Ischemic Stroke Stroke. 03, 2020 | Pubmed ID: 31948385 Computed Tomography Perfusion Identifies Patients With Stroke With Impaired Cardiac Function Stroke. 02, 2020 | Pubmed ID: 31896345 YouTube As a Resource for Evaluating the Unmet Needs of Caregivers of Stroke Survivors Health Informatics Journal. 09, 2020 | Pubmed ID: 31722610 An Online Cross-sectional Survey of the Health Risk Behaviours Among Informal Caregivers Health Promotion Journal of Australia : Official Journal of Australian Association of Health Promotion Professionals. Sep, 2020 | Pubmed ID: 31529552 The Unmet Needs of Carers of Stroke Survivors: An Evaluation of Google Search Results Health Informatics Journal. 06, 2020 | Pubmed ID: 31213117 Contemporary Trends in Stroke Complicating Cardiac Catheterisation Internal Medicine Journal. 07, 2020 | Pubmed ID: 31211489 An Online Intervention for Improving Stroke Survivors' Health-related Quality of Life: Study Protocol for a Randomised Controlled Trial Trials. Aug, 2019 | Pubmed ID: 31399140 Modafinil Treatment Modulates Functional Connectivity in Stroke Survivors with Severe Fatigue Scientific Reports. 07, 2019 | Pubmed ID: 31273283 Choroid Plexus Volume After Stroke International Journal of Stroke : Official Journal of the International Stroke Society. 12, 2019 | Pubmed ID: 31096870 "This is Our Life Now. Our New Normal": A Qualitative Study of the Unmet Needs of Carers of Stroke Survivors PloS One. 2019 | Pubmed ID: 31067286 Influence of Occlusion Site and Baseline Ischemic Core on Outcome in Patients with Ischemic Stroke Neurology. 06, 2019 | Pubmed ID: 31043475 Cognitive Dysfunction is Associated with Abnormal Responses in Cerebral Blood Flow in Patients with Single Ventricular Physiology: Novel Insights from Transcranial Doppler Ultrasound Congenital Heart Disease. Jul, 2019 | Pubmed ID: 30908884 Predicting Modafinil-Treatment Response in Poststroke Fatigue Using Brain Morphometry and Functional Connectivity Stroke. 03, 2019 | Pubmed ID: 30777001 Breaking Up Sitting Time After Stroke - How Much Less Sitting is Needed to Improve Blood Pressure After Stroke (BUST-BP-Dose): Protocol for a Dose-finding Study Contemporary Clinical Trials Communications. Mar, 2019 | Pubmed ID: 30740549 The International Comparison of Systems of Care and Patient Outcomes In Minor Stroke and Tia (InSIST) Study: A Community-based Cohort Study International Journal of Stroke : Official Journal of the International Stroke Society. 02, 2019 | Pubmed ID: 30608031 Single-phase CT Angiography: Collateral Grade is Independent of Scan Weighting Neuroradiology. Jan, 2019 | Pubmed ID: 30288551 Do Powered Over-ground Lower Limb Robotic Exoskeletons Affect Outcomes in the Rehabilitation of People with Acquired Brain Injury? Disability and Rehabilitation. Assistive Technology. 11, 2019 | Pubmed ID: 30241453 White Matter Degeneration After Ischemic Stroke: A Longitudinal Diffusion Tensor Imaging Study Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. 01, 2019 | Pubmed ID: 30160814 Evaluation of Three Measures of Cardiorespiratory Fitness in Independently Ambulant Stroke Survivors Physiotherapy Theory and Practice. Jul, 2019 | Pubmed ID: 29601228 Thresholds for Infarction Vary Between Gray Matter and White Matter in Acute Ischemic Stroke: A CT Perfusion Study Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 03, 2019 | Pubmed ID: 29172990 Growth Hormone Deficiency Is Frequent After Recent Stroke Frontiers in Neurology. 2018 | Pubmed ID: 30237782 Breaking Up Sitting Time After Stroke (BUST-stroke) International Journal of Stroke : Official Journal of the International Stroke Society. 12, 2018 | Pubmed ID: 30226448 Frequent, Short Bouts of Light-intensity Exercises While Standing Decreases Systolic Blood Pressure: Breaking Up Sitting Time After Stroke (BUST-Stroke) Trial International Journal of Stroke : Official Journal of the International Stroke Society. 12, 2018 | Pubmed ID: 30223728 Heptanoate is Neuroprotective in Vitro but Triheptanoin Post-treatment Did Not Protect Against Middle Cerebral Artery Occlusion in Rats Neuroscience Letters. 09, 2018 | Pubmed ID: 30076987 Intravenous Thrombolysis May Not Improve Clinical Outcome of Acute Ischemic Stroke Patients Without a Baseline Vessel Occlusion Frontiers in Neurology. 2018 | Pubmed ID: 29928251 Correction for Delay and Dispersion Results in More Accurate Cerebral Blood Flow Ischemic Core Measurement in Acute Stroke Stroke. 04, 2018 | Pubmed ID: 29500248 Tissue Is More Important Than Time in Stroke Patients Being Assessed for Thrombolysis Frontiers in Neurology. 2018 | Pubmed ID: 29467716 The Unmet Needs of Informal Carers of Stroke Survivors: a Protocol for a Systematic Review of Quantitative and Qualitative Studies BMJ Open. 01, 2018 | Pubmed ID: 29391371 Boredom in Patients with Acquired Brain Injuries During Inpatient Rehabilitation: a Scoping Review Disability and Rehabilitation. 11, 2018 | Pubmed ID: 28760011 The Influence of Initial Stroke Severity on Mortality, Overall Functional Outcome and In-hospital Placement at 90 Days Following Acute Ischemic Stroke: A Tertiary Hospital Stroke Register Study Neurology India. Nov-Dec, 2017 | Pubmed ID: 29133696 Cardiorespiratory Fitness and Walking Endurance Improvements After 12 Months of an Individualised Home and Community-based Exercise Programme for People After Stroke Brain Injury. 2017 | Pubmed ID: 28872360 Tenecteplase in Ischemic Stroke Offers Improved Recanalization: Analysis of 2 Trials Neurology. Jul, 2017 | Pubmed ID: 28576782 Validation of the National Institutes of Health Stroke Scale-8 to Detect Large Vessel Occlusion in Ischemic Stroke Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. Jul, 2017 | Pubmed ID: 28457621 The Role of Ca-calmodulin Stimulated Protein Kinase II in Ischaemic Stroke - A Potential Target for Neuroprotective Therapies Neurochemistry International. Jul, 2017 | Pubmed ID: 28153786 Validating a Predictive Model of Acute Advanced Imaging Biomarkers in Ischemic Stroke Stroke. 03, 2017 | Pubmed ID: 28104836 Ischaemia- and Excitotoxicity-induced CaMKII-Mediated Neuronal Cell Death: The Relative Roles of CaMKII Autophosphorylation at T286 and T253 Neurochemistry International. Mar, 2017 | Pubmed ID: 28065796 Recent Progress in Translational Research on Neurovascular and Neurodegenerative Disorders Restorative Neurology and Neuroscience. 2017 | Pubmed ID: 28059802 The Establishment of a Telestroke Service Using Multimodal CT Imaging Decision Assistance: "Turning on the Fog Lights" Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. Mar, 2017 | Pubmed ID: 27887976 Breaking Up Sitting Time After Stroke (BUST-Stroke) International Journal of Stroke : Official Journal of the International Stroke Society. 06, 2017 | Pubmed ID: 27794137 Independently Ambulant, Community-dwelling Stroke Survivors Have Reduced Cardiorespiratory Fitness, Mobility and Knee Strength Compared to an Age- and Gender-matched Cohort Topics in Stroke Rehabilitation. 04, 2017 | Pubmed ID: 27670905 Effectiveness of a Brief Dietetic Intervention for Hyperlipidaemic Adults Using Individually-Tailored Dietary Feedback Healthcare (Basel, Switzerland). Oct, 2016 | Pubmed ID: 27727165 The Role of Family in a Dietary Risk Reduction Intervention for Cardiovascular Disease Healthcare (Basel, Switzerland). Sep, 2016 | Pubmed ID: 27706027 A Home- and Community-Based Physical Activity Program Can Improve the Cardiorespiratory Fitness and Walking Capacity of Stroke Survivors Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. Oct, 2016 | Pubmed ID: 27378733 Sonothrombolysis with BR38 Microbubbles Improves Microvascular Patency in a Rat Model of Stroke PloS One. 2016 | Pubmed ID: 27077372 Thrombolytic Recanalization of Carotid Arteries Is Highly Dependent on Degree of Stenosis, Despite Sonothrombolysis Journal of the American Heart Association. Feb, 2016 | Pubmed ID: 26908405 Intracranial Pressure and Collateral Blood Flow Stroke. 06, 2016 | Pubmed ID: 26786117 Global White Matter Hypoperfusion on CT Predicts Larger Infarcts and Hemorrhagic Transformation After Acute Ischemia CNS Neuroscience & Therapeutics. Mar, 2016 | Pubmed ID: 26775830 Ischemic Penumbra As a Trigger for Intracranial Pressure Rise - A Potential Cause for Collateral Failure and Infarct Progression? Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 05, 2016 | Pubmed ID: 26759431 A Comprehensive Analysis of Metabolic Changes in the Salvaged Penumbra Neuroradiology. Apr, 2016 | Pubmed ID: 26738878 Tissue Plasminogen Activator for Preclinical Stroke Research: Neither "rat" nor "human" Dose Mimics Clinical Recanalization in a Carotid Occlusion Model Scientific Reports. Nov, 2015 | Pubmed ID: 26522691 Feasibility of Recruiting Families into a Heart Disease Prevention Program Based on Dietary Patterns Nutrients. Aug, 2015 | Pubmed ID: 26308048 Perfusion Computed Tomography to Assist Decision Making for Stroke Thrombolysis Brain : a Journal of Neurology. Jul, 2015 | Pubmed ID: 25808369 Chronic Stress Exacerbates Neuronal Loss Associated with Secondary Neurodegeneration and Suppresses Microglial-like Cells Following Focal Motor Cortex Ischemia in the Mouse Brain, Behavior, and Immunity. Aug, 2015 | Pubmed ID: 25749481 Intracranial Pressure Elevation Reduces Flow Through Collateral Vessels and the Penetrating Arterioles They Supply. A Possible Explanation for 'collateral Failure' and Infarct Expansion After Ischemic Stroke Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. May, 2015 | Pubmed ID: 25669909 Platelet Rich Clots Are Resistant to Lysis by Thrombolytic Therapy in a Rat Model of Embolic Stroke Experimental & Translational Stroke Medicine. 2015 | Pubmed ID: 25657829 Intracranial Pressure Elevation After Ischemic Stroke in Rats: Cerebral Edema is Not the Only Cause, and Short-duration Mild Hypothermia is a Highly Effective Preventive Therapy Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Mar, 2015 | Pubmed ID: 25515213 Spectroscopy of Reperfused Tissue After Stroke Reveals Heightened Metabolism in Patients with Good Clinical Outcomes Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Dec, 2014 | Pubmed ID: 25269516 Allopregnanolone and Its Precursor Progesterone Do Not Reduce Injury After Experimental Stroke in Hypertensive Rats - Role of Postoperative Temperature Regulation? PloS One. 2014 | Pubmed ID: 25248155 Cerebrospinal Fluid is Drained Primarily Via the Spinal Canal and Olfactory Route in Young and Aged Spontaneously Hypertensive Rats Fluids and Barriers of the CNS. 2014 | Pubmed ID: 24932405 Exercise Reduces Infarct Volume and Facilitates Neurobehavioral Recovery: Results from a Systematic Review and Meta-analysis of Exercise in Experimental Models of Focal Ischemia Neurorehabilitation and Neural Repair. Oct, 2014 | Pubmed ID: 24553105 Arterial Spin Labeling Versus Bolus-tracking Perfusion in Hyperacute Stroke Stroke. Jan, 2014 | Pubmed ID: 24302482 An Enriched Environment Increases Activity in Stroke Patients Undergoing Rehabilitation in a Mixed Rehabilitation Unit: a Pilot Non-randomized Controlled Trial Disability and Rehabilitation. 2014 | Pubmed ID: 23627534 Inadvertent Occlusion of the Anterior Choroidal Artery Explains Infarct Variability in the Middle Cerebral Artery Thread Occlusion Stroke Model PloS One. 2013 | Pubmed ID: 24069448 Referral and Triage of Patients with Transient Ischemic Attacks to an Acute Access Clinic: Risk Stratification in an Australian Setting International Journal of Stroke : Official Journal of the International Stroke Society. Oct, 2013 | Pubmed ID: 23490207 Assessment of Leptomeningeal Collaterals Using Dynamic CT Angiography in Patients with Acute Ischemic Stroke Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Mar, 2013 | Pubmed ID: 23149554 Exploring the Efficacy of Constraint in Animal Models of Stroke: Meta-analysis and Systematic Review of the Current Evidence Neurorehabilitation and Neural Repair. Jan, 2013 | Pubmed ID: 22714123 αCaMKII is Differentially Regulated in Brain Regions That Exhibit Differing Sensitivities to Ischemia and Excitotoxicity Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Dec, 2012 | Pubmed ID: 22929440 A Randomized Trial of Tenecteplase Versus Alteplase for Acute Ischemic Stroke The New England Journal of Medicine. Mar, 2012 | Pubmed ID: 22435369 Perfusion Computer Tomography: Imaging and Clinical Validation in Acute Ischaemic Stroke Brain : a Journal of Neurology. Nov, 2011 | Pubmed ID: 22075524 Establishing a Rodent Stroke Perfusion Computed Tomography Model International Journal of Stroke : Official Journal of the International Stroke Society. Aug, 2011 | Pubmed ID: 21609409 Acute Stroke Thrombolysis: Time to Dispense with the Clock and Move to Tissue-based Decision Making? Expert Review of Cardiovascular Therapy. Apr, 2011 | Pubmed ID: 21517729 Defining the Extent of Irreversible Brain Ischemia Using Perfusion Computed Tomography Cerebrovascular Diseases (Basel, Switzerland). 2011 | Pubmed ID: 21178348 'Salvaged' Stroke Ischaemic Penumbra Shows Significant Injury: Studies with the Hypoxia Tracer FMISO Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Mar, 2011 | Pubmed ID: 20877386 The Rural Prehospital Acute Stroke Triage (PAST) Trial Protocol: a Controlled Trial for Rapid Facilitated Transport of Rural Acute Stroke Patients to a Regional Stroke Centre International Journal of Stroke : Official Journal of the International Stroke Society. Dec, 2010 | Pubmed ID: 21050409 Trends in Stroke Attack Rates and Case Fatality in the Hunter Region, Australia 1996-2008 Cerebrovascular Diseases (Basel, Switzerland). 2010 | Pubmed ID: 20861621 An Enriched Environment Improves Sensorimotor Function Post-ischemic Stroke Neurorehabilitation and Neural Repair. Nov-Dec, 2010 | Pubmed ID: 20834046 Cardiogenic Shock Complicating Subarachnoid Haemorrhage Diagnosed As Tako Tsubo Cardiomyopathy: a Cautionary Tale Heart, Lung & Circulation. Aug, 2010 | Pubmed ID: 20418161 Inducing Stroke in Aged, Hypertensive, Diabetic Rats Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Apr, 2010 | Pubmed ID: 20068574 Characterisation of the Timing of Binding of the Hypoxia Tracer FMISO After Stroke Brain Research. Sep, 2009 | Pubmed ID: 19595680 The Independent Predictive Utility of Computed Tomography Angiographic Collateral Status in Acute Ischaemic Stroke Brain : a Journal of Neurology. Aug, 2009 | Pubmed ID: 19509116 Improving Access to Acute Stroke Therapies: a Controlled Trial of Organised Pre-hospital and Emergency Care The Medical Journal of Australia. Oct, 2008 | Pubmed ID: 18928434 Characterization of Fluoromisonidazole Binding in Stroke Stroke; a Journal of Cerebral Circulation. Jul, 2006 | Pubmed ID: 16763190 Modification of the Method of Thread Manufacture Improves Stroke Induction Rate and Reduces Mortality After Thread-occlusion of the Middle Cerebral Artery in Young or Aged Rats Journal of Neuroscience Methods. Sep, 2006 | Pubmed ID: 16513179 Ischaemic Tolerance and Mitochondrial Uncoupling--can We Learn from the Cell? Cerebrovascular Diseases (Basel, Switzerland). 2005 | Pubmed ID: 15703472 Imaging the Ischemic Penumbra with 18F-fluoromisonidazole in a Rat Model of Ischemic Stroke Stroke; a Journal of Cerebral Circulation. Apr, 2004 | Pubmed ID: 15017016 A Prospective Study of Predictors of Prolonged Hospital Stay and Disability After Stroke Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. Nov, 2003 | Pubmed ID: 14592613 Seasonal Variation in Stroke in the Hunter Region, Australia: a 5-year Hospital-based Study, 1995-2000 Stroke; a Journal of Cerebral Circulation. May, 2003 | Pubmed ID: 12677016 التعريفي انخفاض حرارة الجسم قصيرة الأجل في الفئران باستخدام نماذج للدراسات دراسة الصلة السريرية والآليات Daniel Omileke1, Steven Bothwell1, Daniel J. Beard1, Nikolce Mackovski1, Sara Azarpeykan1, Kirsten Coupland1, Adjanie Patabendige1, Neil Spratt1,2 1School of Biomedical Sciences and Pharmacy, University of Newcastle, 2Department of Neurology, John Hunter Hospital, Hunter New England Local Health District JoVE 62325 Medicine فوق الجافية قياس الضغط داخل الجمجمة في الفئران باستخدام محول ضغط الألياف الضوئية Lucy Murtha1, Damian McLeod1, Neil Spratt1 1Biomedical Sciences and Pharmacy, The University of Newcastle JoVE 3689 Medicine
التعريفي انخفاض حرارة الجسم قصيرة الأجل في الفئران باستخدام نماذج للدراسات دراسة الصلة السريرية والآليات Daniel Omileke1, Steven Bothwell1, Daniel J. Beard1, Nikolce Mackovski1, Sara Azarpeykan1, Kirsten Coupland1, Adjanie Patabendige1, Neil Spratt1,2 1School of Biomedical Sciences and Pharmacy, University of Newcastle, 2Department of Neurology, John Hunter Hospital, Hunter New England Local Health District JoVE 62325 Medicine
فوق الجافية قياس الضغط داخل الجمجمة في الفئران باستخدام محول ضغط الألياف الضوئية Lucy Murtha1, Damian McLeod1, Neil Spratt1 1Biomedical Sciences and Pharmacy, The University of Newcastle JoVE 3689 Medicine
