Nial J. Wheate Faculty of Pharmacy The University of Sydney Biography Publications Institution JoVE Articles Nial J. Wheate has not added a biography. If you are Nial J. Wheate and would like to personalize this page please email our Author Liaison for assistance. Publications A Cisplatin Slow-release Hydrogel Drug Delivery System Based on a Formulation of the Macrocycle Cucurbit[7]uril, Gelatin and Polyvinyl Alcohol Journal of Inorganic Biochemistry. May, 2014 | Pubmed ID: 24595010 Topical Cream-based Dosage Forms of the Macrocyclic Drug Delivery Vehicle Cucurbit[6]uril PloS One. 2014 | Pubmed ID: 24454850 DNA-based Aptamer Fails As a Simultaneous Cancer Targeting Agent and Drug Delivery Vehicle for a Phenanthroline-based Platinum(II) Complex Journal of Inorganic Biochemistry. Nov, 2013 | Pubmed ID: 23954482 Nanoparticles: the Future for Platinum Drugs or a Research Red Herring? Nanomedicine (London, England). Sep, 2012 | Pubmed ID: 22994954 Combining Aspects of the Platinum Anticancer Drugs Picoplatin and BBR3464 to Synthesize a New Family of Sterically Hindered Dinuclear Complexes; Their Synthesis, Binding Kinetics and Cytotoxicity Dalton Transactions (Cambridge, England : 2003). Oct, 2012 | Pubmed ID: 22886151 Cucurbit[7]uril Encapsulated Cisplatin Overcomes Cisplatin Resistance Via a Pharmacokinetic Effect Metallomics : Integrated Biometal Science. Jun, 2012 | Pubmed ID: 22610518 Cisplatin-tethered Gold Nanoparticles That Exhibit Enhanced Reproducibility, Drug Loading, and Stability: a Step Closer to Pharmaceutical Approval? Inorganic Chemistry. Mar, 2012 | Pubmed ID: 22390791 Evaluation of Anionic Half Generation 3.5-6.5 Poly(amidoamine) Dendrimers As Delivery Vehicles for the Active Component of the Anticancer Drug Cisplatin Journal of Inorganic Biochemistry. Sep, 2011 | Pubmed ID: 21704583 Microwave Synthesis of Cucurbit[n]urils Future Medicinal Chemistry. Feb, 2010 | Pubmed ID: 21426190 Synthesis, Processing and Solid State Excipient Interactions of Cucurbit[6]uril and Its Formulation into Tablets for Oral Drug Delivery Molecular Pharmaceutics. Dec, 2010 | Pubmed ID: 20669974 The Status of Platinum Anticancer Drugs in the Clinic and in Clinical Trials Dalton Transactions (Cambridge, England : 2003). Sep, 2010 | Pubmed ID: 20593091 Gold Nanoparticles for the Improved Anticancer Drug Delivery of the Active Component of Oxaliplatin Journal of the American Chemical Society. Apr, 2010 | Pubmed ID: 20225865 Solid State Stabilisation of the Orally Delivered Drugs Atenolol, Glibenclamide, Memantine and Paracetamol Through Their Complexation with Cucurbit[7]uril Organic & Biomolecular Chemistry. Feb, 2010 | Pubmed ID: 20135032 A Chemical Preformulation Study of a Host-guest Complex of Cucurbit[7]uril and a Multinuclear Platinum Agent for Enhanced Anticancer Drug Delivery Dalton Transactions (Cambridge, England : 2003). Oct, 2009 | Pubmed ID: 19759943 Studies of the Mechanism of Action of Platinum(II) Complexes with Potent Cytotoxicity in Human Cancer Cells Journal of Medicinal Chemistry. Sep, 2009 | Pubmed ID: 19658404 Diffusion-based Studies on the Self-stacking and Nanorod Formation of Platinum(II) Intercalators Chemical Communications (Cambridge, England). Mar, 2009 | Pubmed ID: 19240876 Side-on Binding of P-sulphonatocalix[4]arene to the Dinuclear Platinum Complex Trans-[{PtCl(NH3)2}2mu-dpzm]2+ and Its Implications for Anticancer Drug Delivery Journal of Inorganic Biochemistry. Mar, 2009 | Pubmed ID: 19171382 Anionic PAMAM Dendrimers As Drug Delivery Vehicles for Transition Metal-based Anticancer Drugs Journal of Inorganic Biochemistry. Mar, 2009 | Pubmed ID: 19121543 Improving Platinum(II)-based Anticancer Drug Delivery Using Cucurbit[n]urils Journal of Inorganic Biochemistry. Dec, 2008 | Pubmed ID: 18653238 Substituted Beta-cyclodextrin and Calix[4]arene As Encapsulatory Vehicles for Platinum(II)-based DNA Intercalators Inorganic Chemistry. Aug, 2008 | Pubmed ID: 18597414 Degradation of Bidentate-coordinated Platinum(II)-based DNA Intercalators by Reduced L-glutathione Journal of Medicinal Chemistry. May, 2008 | Pubmed ID: 18412325 Examination of Cucurbit[7]uril and Its Host-guest Complexes by Diffusion Nuclear Magnetic Resonance The Journal of Physical Chemistry. B. Feb, 2008 | Pubmed ID: 18247599 Novel Platinum(II)-based Anticancer Complexes and Molecular Hosts As Their Drug Delivery Vehicles Dalton Transactions (Cambridge, England : 2003). Nov, 2007 | Pubmed ID: 17992290 Encapsulation of Platinum(II)-based DNA Intercalators Within Cucurbit[6,7,8]urils Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Sep, 2007 | Pubmed ID: 17653578 DNA Intercalators in Cancer Therapy: Organic and Inorganic Drugs and Their Spectroscopic Tools of Analysis Mini Reviews in Medicinal Chemistry. Jun, 2007 | Pubmed ID: 17584161 The Effect of Ancillary Ligand Chirality and Phenanthroline Functional Group Substitution on the Cytotoxicity of Platinum(II)-based Metallointercalators Journal of Inorganic Biochemistry. Jul, 2007 | Pubmed ID: 17544512 Synthesis of DNA-sequence-selective Hairpin Polyamide Platinum Complexes Chemistry (Weinheim an Der Bergstrasse, Germany). 2007 | Pubmed ID: 17226877 Polyamide Platinum Anticancer Complexes Designed to Target Specific DNA Sequences Inorganic Chemistry. Jul, 2006 | Pubmed ID: 16842007 Cucurbit[n]uril Binding of Platinum Anticancer Complexes Dalton Transactions (Cambridge, England : 2003). Jan, 2006 | Pubmed ID: 16395444 Multi-nuclear Platinum Drugs: a New Paradigm in Chemotherapy Current Medicinal Chemistry. Anti-cancer Agents. May, 2005 | Pubmed ID: 15992354 Potential Adenine and Minor Groove Binding Platinum Complexes Journal of Inorganic Biochemistry. Oct, 2004 | Pubmed ID: 15458819 Multi-nuclear Platinum Complexes Encapsulated in Cucurbit[n]uril As an Approach to Reduce Toxicity in Cancer Treatment Chemical Communications (Cambridge, England). Jun, 2004 | Pubmed ID: 15179496 Ammide Accoppiamento di reazione per la sintesi di leganti a base di Bispyridine e il loro Complessazione di platino come diciclici agenti antitumorali Michael G. Apps1, Ben W. Johnson2, Oliver B. Sutcliffe3, Sarah D. Brown4, Nial J. Wheate1 1Faculty of Pharmacy, The University of Sydney, 2School of Science and Health, University of Western Sydney, 3Division of Chemistry and Environmental Science, School of Science and the Environment, Manchester Metropolitan University, 4Nature Publishing Group JoVE 51740 Chemistry
Ammide Accoppiamento di reazione per la sintesi di leganti a base di Bispyridine e il loro Complessazione di platino come diciclici agenti antitumorali Michael G. Apps1, Ben W. Johnson2, Oliver B. Sutcliffe3, Sarah D. Brown4, Nial J. Wheate1 1Faculty of Pharmacy, The University of Sydney, 2School of Science and Health, University of Western Sydney, 3Division of Chemistry and Environmental Science, School of Science and the Environment, Manchester Metropolitan University, 4Nature Publishing Group JoVE 51740 Chemistry
