Nicholas J. Harmer Department of Biosciences University of Exeter Biography Publications Institution JoVE Articles Nicholas J. Harmer has not added a biography. If you are Nicholas J. Harmer and would like to personalize this page please email our Author Liaison for assistance. Publications Structural Insights into WcbI, a Novel Polysaccharide-biosynthesis Enzyme IUCrJ. Jan, 2014 | Pubmed ID: 25075317 A Structural Biology Approach Enables the Development of Antimicrobials Targeting Bacterial Immunophilins Antimicrobial Agents and Chemotherapy. 2014 | Pubmed ID: 24366729 Myosin-5, Kinesin-1 and Myosin-17 Cooperate in Secretion of Fungal Chitin Synthase The EMBO Journal. Jan, 2012 | Pubmed ID: 22027862 A Burkholderia Pseudomallei Macrophage Infectivity Potentiator-like Protein Has Rapamycin-inhibitable Peptidylprolyl Isomerase Activity and Pleiotropic Effects on Virulence Infection and Immunity. Nov, 2011 | Pubmed ID: 21859853 A Novel FK-506-binding-like Protein That Lacks Peptidyl-prolyl Isomerase Activity is Involved in Intracellular Infection and in Vivo Virulence of Burkholderia Pseudomallei Microbiology (Reading, England). Sep, 2011 | Pubmed ID: 21680634 The Structure of a Burkholderia Pseudomallei Immunophilin-inhibitor Complex Reveals New Approaches to Antimicrobial Development The Biochemical Journal. Aug, 2011 | Pubmed ID: 21574961 The Structure of Sedoheptulose-7-phosphate Isomerase from Burkholderia Pseudomallei Reveals a Zinc Binding Site at the Heart of the Active Site Journal of Molecular Biology. Jul, 2010 | Pubmed ID: 20447408 Evidence That Heparin Saccharides Promote FGF2 Mitogenesis Through Two Distinct Mechanisms The Journal of Biological Chemistry. May, 2008 | Pubmed ID: 18281281 Predicting Protein Function from Structure--the Roles of Short-chain Dehydrogenase/reductase Enzymes in Bordetella O-antigen Biosynthesis Journal of Molecular Biology. Nov, 2007 | Pubmed ID: 17950751 Cloning, Expression, Purification and Preliminary Crystallographic Analysis of the Short-chain Dehydrogenase Enzymes WbmF, WbmG and WbmH from Bordetella Bronchiseptica Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Aug, 2007 | Pubmed ID: 17671375 Expression and Purification of Recombinant Human Fibroblast Growth Factor Receptor in Escherichia Coli Protein Expression and Purification. Sep, 2006 | Pubmed ID: 16750394 Structural Biology and Bioinformatics in Drug Design: Opportunities and Challenges for Target Identification and Lead Discovery Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Mar, 2006 | Pubmed ID: 16524830 Multimers of the Fibroblast Growth Factor (FGF)-FGF Receptor-saccharide Complex Are Formed on Long Oligomers of Heparin The Biochemical Journal. Feb, 2006 | Pubmed ID: 16223363 Cooperative Dimerization of Fibroblast Growth Factor 1 (FGF1) Upon a Single Heparin Saccharide May Drive the Formation of 2:2:1 FGF1.FGFR2c.heparin Ternary Complexes The Journal of Biological Chemistry. Dec, 2005 | Pubmed ID: 16219767 1.15 A Crystal Structure of the X. Tropicalis Spred1 EVH1 Domain Suggests a Fourth Distinct Peptide-binding Mechanism Within the EVH1 Family FEBS Letters. Feb, 2005 | Pubmed ID: 15710406 Towards a Resolution of the Stoichiometry of the Fibroblast Growth Factor (FGF)-FGF Receptor-heparin Complex Journal of Molecular Biology. Jun, 2004 | Pubmed ID: 15165853 The Crystal Structure of Fibroblast Growth Factor (FGF) 19 Reveals Novel Features of the FGF Family and Offers a Structural Basis for Its Unusual Receptor Affinity Biochemistry. Jan, 2004 | Pubmed ID: 14730967 The Structural Biology of Growth Factor Receptor Activation Biophysical Chemistry. 2003 | Pubmed ID: 12646390 A Tyrosine703serine Polymorphism of CD109 Defines the Gov Platelet Alloantigens Blood. Mar, 2002 | Pubmed ID: 11861285 נחישות של אינטראקציות חלבון ליגנד שימוש דיפרנציאל סריקת Fluorimetry Mirella Vivoli1, Halina R. Novak1, Jennifer A. Littlechild1, Nicholas J. Harmer1 1Department of Biosciences, University of Exeter Biology
נחישות של אינטראקציות חלבון ליגנד שימוש דיפרנציאל סריקת Fluorimetry Mirella Vivoli1, Halina R. Novak1, Jennifer A. Littlechild1, Nicholas J. Harmer1 1Department of Biosciences, University of Exeter Biology