Nichole R. Klatt Department of Pharmaceutics Washington National Primate Research Center, University of Washington Biography Publications Institution JoVE Articles Nichole R. Klatt has not added a biography. If you are Nichole R. Klatt and would like to personalize this page please email our Author Liaison for assistance. Publications Loss of Immune Homeostasis Dictates SHIV Rebound After Stem-cell Transplantation JCI Insight. Feb, 2017 | Pubmed ID: 28239658 Microbiome Composition and Function Drives Wound-Healing Impairment in the Female Genital Tract PLoS Pathogens. Sep, 2016 | Pubmed ID: 27656899 Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys PloS One. 2016 | Pubmed ID: 27227993 Effects of Fecal Microbial Transplantation on Microbiome and Immunity in Simian Immunodeficiency Virus-Infected Macaques Journal of Virology. May, 2016 | Pubmed ID: 26937040 Enhancement of Microbiota in Healthy Macaques Results in Beneficial Modulation of Mucosal and Systemic Immune Function Journal of Immunology (Baltimore, Md. : 1950). Mar, 2016 | Pubmed ID: 26826246 Microbial Translocation and Microbiome Dysbiosis in HIV-associated Immune Activation Current Opinion in HIV and AIDS. Mar, 2016 | Pubmed ID: 26679414 SIV-induced Translocation of Bacterial Products in the Liver Mobilizes Myeloid Dendritic and Natural Killer Cells Associated With Liver Damage The Journal of Infectious Diseases. Feb, 2016 | Pubmed ID: 26238685 Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques Cell Reports. Nov, 2015 | Pubmed ID: 26586432 Experimental Colitis in SIV-uninfected Rhesus Macaques Recapitulates Important Features of Pathogenic SIV Infection Nature Communications. 2015 | Pubmed ID: 26282376 HIV and Mucosal Barrier Interactions: Consequences for Transmission and Pathogenesis Current Opinion in Immunology. Oct, 2015 | Pubmed ID: 26151777 Hypercytotoxicity and Rapid Loss of NKp44+ Innate Lymphoid Cells During Acute SIV Infection PLoS Pathogens. Dec, 2014 | Pubmed ID: 25503264 Limited HIV Infection of Central Memory and Stem Cell Memory CD4+ T Cells is Associated with Lack of Progression in Viremic Individuals PLoS Pathogens. Aug, 2014 | Pubmed ID: 25167059 HIV Vaccine Trial Exploits a Dual and Central Role for Innate Immunity Journal of Virology. Oct, 2014 | Pubmed ID: 25122775 HIV Transmission. Selection Bias at the Heterosexual HIV-1 Transmission Bottleneck Science (New York, N.Y.). Jul, 2014 | Pubmed ID: 25013080 Homeostatic Cytokines Induce CD4 Downregulation in African Green Monkeys Independently of Antigen Exposure to Generate Simian Immunodeficiency Virus-resistant CD8αα T Cells Journal of Virology. Sep, 2014 | Pubmed ID: 24991011 Residual Immune Dysregulation Syndrome in Treated HIV Infection Advances in Immunology. 2013 | Pubmed ID: 23886064 High Production Rates Sustain in Vivo Levels of PD-1high Simian Immunodeficiency Virus-specific CD8 T Cells in the Face of Rapid Clearance Journal of Virology. Sep, 2013 | Pubmed ID: 23824823 Immune Activation and HIV Persistence: Implications for Curative Approaches to HIV Infection Immunological Reviews. Jul, 2013 | Pubmed ID: 23772629 Rate of AIDS Progression is Associated with Gastrointestinal Dysfunction in Simian Immunodeficiency Virus-infected Pigtail Macaques Journal of Immunology (Baltimore, Md. : 1950). Mar, 2013 | Pubmed ID: 23401593 Probiotic/prebiotic Supplementation of Antiretrovirals Improves Gastrointestinal Immunity in SIV-infected Macaques The Journal of Clinical Investigation. Feb, 2013 | Pubmed ID: 23321668 Superior T Memory Stem Cell Persistence Supports Long-lived T Cell Memory The Journal of Clinical Investigation. Feb, 2013 | Pubmed ID: 23281401 Transcriptional Profiling of Experimental CD8(+) Lymphocyte Depletion in Rhesus Macaques Infected with Simian Immunodeficiency Virus SIVmac239 Journal of Virology. Jan, 2013 | Pubmed ID: 23097439 Microbial Translocation, Immune Activation, and HIV Disease Trends in Microbiology. Jan, 2013 | Pubmed ID: 23062765 CD4+ T Cells and HIV: A Paradoxical Pas De Deux Science Translational Medicine. Feb, 2012 | Pubmed ID: 22378922 Nonpathogenic Simian Immunodeficiency Virus Infections Cold Spring Harbor Perspectives in Medicine. Jan, 2012 | Pubmed ID: 22315718 Dynamics of Simian Immunodeficiency Virus SIVmac239 Infection in Pigtail Macaques Journal of Virology. Jan, 2012 | Pubmed ID: 22090099 Depletion of CD4⁺ T Cells Abrogates Post-peak Decline of Viremia in SIV-infected Rhesus Macaques The Journal of Clinical Investigation. Nov, 2011 | Pubmed ID: 22005304 Why Don't CD8+ T Cells Reduce the Lifespan of SIV-infected Cells in Vivo? PLoS Computational Biology. Sep, 2011 | Pubmed ID: 21990968 SIV Infection of Rhesus Macaques Results in Dysfunctional T- and B-cell Responses to Neo and Recall Leishmania Major Vaccination Blood. Nov, 2011 | Pubmed ID: 21960586 CD4-like Immunological Function by CD4- T Cells in Multiple Natural Hosts of Simian Immunodeficiency Virus Journal of Virology. Sep, 2011 | Pubmed ID: 21715501 Viral CTL Escape Mutants Are Generated in Lymph Nodes and Subsequently Become Fixed in Plasma and Rectal Mucosa During Acute SIV Infection of Macaques PLoS Pathogens. May, 2011 | Pubmed ID: 21625590 Damaged Intestinal Epithelial Integrity Linked to Microbial Translocation in Pathogenic Simian Immunodeficiency Virus Infections PLoS Pathogens. 2010 | Pubmed ID: 20808901 Mechanisms Underlying γδ T-cell Subset Perturbations in SIV-infected Asian Rhesus Macaques Blood. Nov, 2010 | Pubmed ID: 20660793 Reconstitution of CD4 T Cells in Bronchoalveolar Lavage Fluid After Initiation of Highly Active Antiretroviral Therapy Journal of Virology. Sep, 2010 | Pubmed ID: 20610726 Th17 Cell Dynamics in HIV Infection Current Opinion in HIV and AIDS. Mar, 2010 | Pubmed ID: 20543590 Downregulation of Robust Acute Type I Interferon Responses Distinguishes Nonpathogenic Simian Immunodeficiency Virus (SIV) Infection of Natural Hosts from Pathogenic SIV Infection of Rhesus Macaques Journal of Virology. Aug, 2010 | Pubmed ID: 20484518 Lineage-specific T-cell Reconstitution Following in Vivo CD4+ and CD8+ Lymphocyte Depletion in Nonhuman Primates Blood. Aug, 2010 | Pubmed ID: 20484087 CD8+ Lymphocytes Control Viral Replication in SIVmac239-infected Rhesus Macaques Without Decreasing the Lifespan of Productively Infected Cells PLoS Pathogens. Jan, 2010 | Pubmed ID: 20126441 Global Genomic Analysis Reveals Rapid Control of a Robust Innate Response in SIV-infected Sooty Mangabeys The Journal of Clinical Investigation. Dec, 2009 | Pubmed ID: 19959874 Vaccine-induced, Simian Immunodeficiency Virus-specific CD8+ T Cells Reduce Virus Replication but Do Not Protect from Simian Immunodeficiency Virus Disease Progression Journal of Immunology (Baltimore, Md. : 1950). Jul, 2009 | Pubmed ID: 19542473 CD4 Downregulation by Memory CD4+ T Cells in Vivo Renders African Green Monkeys Resistant to Progressive SIVagm Infection Nature Medicine. Aug, 2009 | Pubmed ID: 19525963 Bone Marrow-based Homeostatic Proliferation of Mature T Cells in Nonhuman Primates: Implications for AIDS Pathogenesis Blood. Jan, 2009 | Pubmed ID: 18832134 Availability of Activated CD4+ T Cells Dictates the Level of Viremia in Naturally SIV-infected Sooty Mangabeys The Journal of Clinical Investigation. Jun, 2008 | Pubmed ID: 18497876 CD127 and CD25 Expression Defines CD4+ T Cell Subsets That Are Differentially Depleted During HIV Infection Journal of Immunology (Baltimore, Md. : 1950). Apr, 2008 | Pubmed ID: 18390743 Short-lived Infected Cells Support Virus Replication in Sooty Mangabeys Naturally Infected with Simian Immunodeficiency Virus: Implications for AIDS Pathogenesis Journal of Virology. Apr, 2008 | Pubmed ID: 18216113 Severe Depletion of Mucosal CD4+ T Cells in AIDS-free Simian Immunodeficiency Virus-infected Sooty Mangabeys Journal of Immunology (Baltimore, Md. : 1950). Sep, 2007 | Pubmed ID: 17709517 Laparoscopische techniek voor seriële Verzameling van lever en mesenteriale lymfeklieren in makaken Alexander S. Zevin1, Cassie Moats2, Drew May2, Solomon Wangari2, Charlene Miller1, Joel Ahrens2, Naoto Iwayama2, Megan Brown2, Debbie Bratt2, Nichole R. Klatt1, Jeremy Smedley2 1Department of Pharmaceutics, Washington National Primate Research Center, University of Washington, 2Division of Primate Resources, Washington National Primate Research Center, University of Washington JoVE 55617 Medicine
Laparoscopische techniek voor seriële Verzameling van lever en mesenteriale lymfeklieren in makaken Alexander S. Zevin1, Cassie Moats2, Drew May2, Solomon Wangari2, Charlene Miller1, Joel Ahrens2, Naoto Iwayama2, Megan Brown2, Debbie Bratt2, Nichole R. Klatt1, Jeremy Smedley2 1Department of Pharmaceutics, Washington National Primate Research Center, University of Washington, 2Division of Primate Resources, Washington National Primate Research Center, University of Washington JoVE 55617 Medicine
