Nichole R. Klatt

Publications

• Loss of Immune Homeostasis Dictates SHIV Rebound After Stem-cell Transplantation
  JCI Insight. Feb, 2017  |   Pubmed ID: 28239658
• Microbiome Composition and Function Drives Wound-Healing Impairment in the Female Genital Tract
  PLoS Pathogens. Sep, 2016  |   Pubmed ID: 27656899
• Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys
  PloS One. 2016  |   Pubmed ID: 27227993
• Effects of Fecal Microbial Transplantation on Microbiome and Immunity in Simian Immunodeficiency Virus-Infected Macaques
  Journal of Virology. May, 2016  |   Pubmed ID: 26937040
• Enhancement of Microbiota in Healthy Macaques Results in Beneficial Modulation of Mucosal and Systemic Immune Function
  Journal of Immunology (Baltimore, Md. : 1950). Mar, 2016  |   Pubmed ID: 26826246
• Microbial Translocation and Microbiome Dysbiosis in HIV-associated Immune Activation
  Current Opinion in HIV and AIDS. Mar, 2016  |   Pubmed ID: 26679414
• SIV-induced Translocation of Bacterial Products in the Liver Mobilizes Myeloid Dendritic and Natural Killer Cells Associated With Liver Damage
  The Journal of Infectious Diseases. Feb, 2016  |   Pubmed ID: 26238685
• Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques
  Cell Reports. Nov, 2015  |   Pubmed ID: 26586432
• Experimental Colitis in SIV-uninfected Rhesus Macaques Recapitulates Important Features of Pathogenic SIV Infection
  Nature Communications. 2015  |   Pubmed ID: 26282376
• HIV and Mucosal Barrier Interactions: Consequences for Transmission and Pathogenesis
  Current Opinion in Immunology. Oct, 2015  |   Pubmed ID: 26151777
• Hypercytotoxicity and Rapid Loss of NKp44+ Innate Lymphoid Cells During Acute SIV Infection
  PLoS Pathogens. Dec, 2014  |   Pubmed ID: 25503264
• Limited HIV Infection of Central Memory and Stem Cell Memory CD4+ T Cells is Associated with Lack of Progression in Viremic Individuals
  PLoS Pathogens. Aug, 2014  |   Pubmed ID: 25167059
• HIV Vaccine Trial Exploits a Dual and Central Role for Innate Immunity
  Journal of Virology. Oct, 2014  |   Pubmed ID: 25122775
• HIV Transmission. Selection Bias at the Heterosexual HIV-1 Transmission Bottleneck
  Science (New York, N.Y.). Jul, 2014  |   Pubmed ID: 25013080
• Homeostatic Cytokines Induce CD4 Downregulation in African Green Monkeys Independently of Antigen Exposure to Generate Simian Immunodeficiency Virus-resistant CD8αα T Cells
  Journal of Virology. Sep, 2014  |   Pubmed ID: 24991011
• Residual Immune Dysregulation Syndrome in Treated HIV Infection
  Advances in Immunology. 2013  |   Pubmed ID: 23886064
• High Production Rates Sustain in Vivo Levels of PD-1high Simian Immunodeficiency Virus-specific CD8 T Cells in the Face of Rapid Clearance
  Journal of Virology. Sep, 2013  |   Pubmed ID: 23824823
• Immune Activation and HIV Persistence: Implications for Curative Approaches to HIV Infection
  Immunological Reviews. Jul, 2013  |   Pubmed ID: 23772629
• Rate of AIDS Progression is Associated with Gastrointestinal Dysfunction in Simian Immunodeficiency Virus-infected Pigtail Macaques
  Journal of Immunology (Baltimore, Md. : 1950). Mar, 2013  |   Pubmed ID: 23401593
• Probiotic/prebiotic Supplementation of Antiretrovirals Improves Gastrointestinal Immunity in SIV-infected Macaques
  The Journal of Clinical Investigation. Feb, 2013  |   Pubmed ID: 23321668
• Superior T Memory Stem Cell Persistence Supports Long-lived T Cell Memory
  The Journal of Clinical Investigation. Feb, 2013  |   Pubmed ID: 23281401
• Transcriptional Profiling of Experimental CD8(+) Lymphocyte Depletion in Rhesus Macaques Infected with Simian Immunodeficiency Virus SIVmac239
  Journal of Virology. Jan, 2013  |   Pubmed ID: 23097439
• Microbial Translocation, Immune Activation, and HIV Disease
  Trends in Microbiology. Jan, 2013  |   Pubmed ID: 23062765
• CD4+ T Cells and HIV: A Paradoxical Pas De Deux
  Science Translational Medicine. Feb, 2012  |   Pubmed ID: 22378922
• Nonpathogenic Simian Immunodeficiency Virus Infections
  Cold Spring Harbor Perspectives in Medicine. Jan, 2012  |   Pubmed ID: 22315718
• Dynamics of Simian Immunodeficiency Virus SIVmac239 Infection in Pigtail Macaques
  Journal of Virology. Jan, 2012  |   Pubmed ID: 22090099
• Depletion of CD4⁺ T Cells Abrogates Post-peak Decline of Viremia in SIV-infected Rhesus Macaques
  The Journal of Clinical Investigation. Nov, 2011  |   Pubmed ID: 22005304
• Why Don't CD8+ T Cells Reduce the Lifespan of SIV-infected Cells in Vivo?
  PLoS Computational Biology. Sep, 2011  |   Pubmed ID: 21990968
• SIV Infection of Rhesus Macaques Results in Dysfunctional T- and B-cell Responses to Neo and Recall Leishmania Major Vaccination
  Blood. Nov, 2011  |   Pubmed ID: 21960586
• CD4-like Immunological Function by CD4- T Cells in Multiple Natural Hosts of Simian Immunodeficiency Virus
  Journal of Virology. Sep, 2011  |   Pubmed ID: 21715501
• Viral CTL Escape Mutants Are Generated in Lymph Nodes and Subsequently Become Fixed in Plasma and Rectal Mucosa During Acute SIV Infection of Macaques
  PLoS Pathogens. May, 2011  |   Pubmed ID: 21625590
• Damaged Intestinal Epithelial Integrity Linked to Microbial Translocation in Pathogenic Simian Immunodeficiency Virus Infections
  PLoS Pathogens. 2010  |   Pubmed ID: 20808901
• Mechanisms Underlying γδ T-cell Subset Perturbations in SIV-infected Asian Rhesus Macaques
  Blood. Nov, 2010  |   Pubmed ID: 20660793
• Reconstitution of CD4 T Cells in Bronchoalveolar Lavage Fluid After Initiation of Highly Active Antiretroviral Therapy
  Journal of Virology. Sep, 2010  |   Pubmed ID: 20610726
• Th17 Cell Dynamics in HIV Infection
  Current Opinion in HIV and AIDS. Mar, 2010  |   Pubmed ID: 20543590
• Downregulation of Robust Acute Type I Interferon Responses Distinguishes Nonpathogenic Simian Immunodeficiency Virus (SIV) Infection of Natural Hosts from Pathogenic SIV Infection of Rhesus Macaques
  Journal of Virology. Aug, 2010  |   Pubmed ID: 20484518
• Lineage-specific T-cell Reconstitution Following in Vivo CD4+ and CD8+ Lymphocyte Depletion in Nonhuman Primates
  Blood. Aug, 2010  |   Pubmed ID: 20484087
• CD8+ Lymphocytes Control Viral Replication in SIVmac239-infected Rhesus Macaques Without Decreasing the Lifespan of Productively Infected Cells
  PLoS Pathogens. Jan, 2010  |   Pubmed ID: 20126441
• Global Genomic Analysis Reveals Rapid Control of a Robust Innate Response in SIV-infected Sooty Mangabeys
  The Journal of Clinical Investigation. Dec, 2009  |   Pubmed ID: 19959874
• Vaccine-induced, Simian Immunodeficiency Virus-specific CD8+ T Cells Reduce Virus Replication but Do Not Protect from Simian Immunodeficiency Virus Disease Progression
  Journal of Immunology (Baltimore, Md. : 1950). Jul, 2009  |   Pubmed ID: 19542473
• CD4 Downregulation by Memory CD4+ T Cells in Vivo Renders African Green Monkeys Resistant to Progressive SIVagm Infection
  Nature Medicine. Aug, 2009  |   Pubmed ID: 19525963
• Bone Marrow-based Homeostatic Proliferation of Mature T Cells in Nonhuman Primates: Implications for AIDS Pathogenesis
  Blood. Jan, 2009  |   Pubmed ID: 18832134
• Availability of Activated CD4+ T Cells Dictates the Level of Viremia in Naturally SIV-infected Sooty Mangabeys
  The Journal of Clinical Investigation. Jun, 2008  |   Pubmed ID: 18497876
• CD127 and CD25 Expression Defines CD4+ T Cell Subsets That Are Differentially Depleted During HIV Infection
  Journal of Immunology (Baltimore, Md. : 1950). Apr, 2008  |   Pubmed ID: 18390743
• Short-lived Infected Cells Support Virus Replication in Sooty Mangabeys Naturally Infected with Simian Immunodeficiency Virus: Implications for AIDS Pathogenesis
  Journal of Virology. Apr, 2008  |   Pubmed ID: 18216113
• Severe Depletion of Mucosal CD4+ T Cells in AIDS-free Simian Immunodeficiency Virus-infected Sooty Mangabeys
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 2007  |   Pubmed ID: 17709517