Nigel Mackman Division of Hematology, UNC Blood Research Center University of North Carolina at Chapel Hill Biography Publications Institution JoVE Articles Nigel Mackman has not added a biography. If you are Nigel Mackman and would like to personalize this page please email our Author Liaison for assistance. Publications Tissue Factor Binds to and Inhibits Interferon-α Receptor 1 Signaling Immunity. Dec, 2023 | Pubmed ID: 38141610 Commentary: Tissue Factor As a Potential Coagulative/vascular Marker in Relapsing-remitting Multiple Sclerosis Frontiers in Immunology. 2023 | Pubmed ID: 38106419 Biomarkers of Bleeding and Venous Thromboembolism in Patients with Acute Leukemia MedRxiv : the Preprint Server for Health Sciences. Oct, 2023 | Pubmed ID: 37905148 Mice Expressing Nonpolymerizable Fibrinogen Have Reduced Arterial and Venous Thrombosis with Preserved Hemostasis Blood. Oct, 2023 | Pubmed ID: 37832029 Tissue Factor Pathway Inhibitor is Associated with Risk of Venous Thromboembolism and All-cause Mortality in Patients with Cancer Haematologica. Oct, 2023 | Pubmed ID: 37822244 Regulation of Von Willebrand Factor by ADAMTS13 Ameliorates Lipopolysaccharide-induced Lung Injury in Mice International Journal of Hematology. Dec, 2023 | Pubmed ID: 37759076 "High Plasma Levels of C1-inhibitor Are Associated with Lower Risk of Future Venous Thromboembolism": Reply Journal of Thrombosis and Haemostasis : JTH. Oct, 2023 | Pubmed ID: 37739598 "C1-inhibitor Levels and Venous Thromboembolism: Results from a Mendelian Randomization Study": Comment from Grover Et al Journal of Thrombosis and Haemostasis : JTH. Oct, 2023 | Pubmed ID: 37739595 APC-PAR1-R46 Signaling Limits CXCL1 Expression During Poly IC-induced Airway Inflammation in Mice Journal of Thrombosis and Haemostasis : JTH. Nov, 2023 | Pubmed ID: 37634652 Neutrophil Extracellular Trap Formation is an Independent Risk Factor for Occult Cancer in Patients Presenting with Venous Thromboembolism Journal of Thrombosis and Haemostasis : JTH. Nov, 2023 | Pubmed ID: 37479035 Heat Shock Protein 47 and Venous Thrombosis: Letting Sleeping Bears Lie Journal of Thrombosis and Haemostasis : JTH. Oct, 2023 | Pubmed ID: 37473845 Tissue Factor Activates the Coagulation Cascade in Mouse Models of Acute Promyelocytic Leukemia Blood Advances. Sep, 2023 | Pubmed ID: 37450381 Detection of Tissue Factor-positive Extracellular Vesicles Using the ExoView R100 System Research and Practice in Thrombosis and Haemostasis. May, 2023 | Pubmed ID: 37333992 Evaluation of Four Commercial ELISAs to Measure Tissue Factor in Human Plasma Research and Practice in Thrombosis and Haemostasis. Mar, 2023 | Pubmed ID: 37275179 Monocyte Tissue Factor Expression: Lipopolysaccharide Induction and Roles in Pathological Activation of Coagulation Thrombosis and Haemostasis. Nov, 2023 | Pubmed ID: 37168007 Tissue Factor-positive Extracellular Vesicles in Plasma Are Not Associated with Venous Thromboembolism in Patients with Ovarian Cancer Research and Practice in Thrombosis and Haemostasis. Mar, 2023 | Pubmed ID: 37128624 Mechanisms of Cancer-associated Thrombosis Research and Practice in Thrombosis and Haemostasis. Mar, 2023 | Pubmed ID: 37122533 Tissue Factor Activity of Small and Large Extracellular Vesicles in Different Diseases Research and Practice in Thrombosis and Haemostasis. Mar, 2023 | Pubmed ID: 37012986 High Plasma Levels of C1-inhibitor Are Associated with Lower Risk of Future Venous Thromboembolism Journal of Thrombosis and Haemostasis : JTH. Jul, 2023 | Pubmed ID: 37003465 "A Rapid, Sensitive, and Specific Assay to Measure Tissue Factor Activity Based on Chromogenic Determination of Thrombin Generation": Comment from Tanratana Et al Journal of Thrombosis and Haemostasis : JTH. Apr, 2023 | Pubmed ID: 36990515 Loss of P2Y Receptor Desensitization Does Not Impact Hemostasis or Thrombosis Despite Increased Platelet Reactivity In vitro Journal of Thrombosis and Haemostasis : JTH. Jul, 2023 | Pubmed ID: 36958516 Decreased Platelet Reactivity and Function in a Mouse Model of Human Pancreatic Cancer Thrombosis and Haemostasis. May, 2023 | Pubmed ID: 36716775 C1 Inhibitor Deficiency Enhances Contact Pathway-mediated Activation of Coagulation And venous Thrombosis Blood. May, 2023 | Pubmed ID: 36701760 "Hereditary Angioedema is Associated with an Increased Risk of Venous Thromboembolism": Reply Journal of Thrombosis and Haemostasis : JTH. Jan, 2023 | Pubmed ID: 36695383 A Novel Mouse Whole Blood Thrombin Generation Assay Sensitive To FXI- and FIX-mediated Amplification of Coagulation Blood Advances. May, 2023 | Pubmed ID: 36583671 Thrombin-mediated Activation of PAR1 Enhances Doxorubicin-induced Cardiac Injury in Mice Blood Advances. May, 2023 | Pubmed ID: 36477178 Circulating Tumor Cells and Cancer-Associated Venous Thrombosis: A Missing Link Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2023 | Pubmed ID: 36453278 Cardiovascular Disease and Thrombosis in HIV Infection Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2023 | Pubmed ID: 36453273 Neutrophil Extracellular Traps and Cancer-associated Thrombosis Thrombosis Research. May, 2022 | Pubmed ID: 36210559 Tissue Factor and COVID-19: An Update Current Drug Targets. Nov, 2022 | Pubmed ID: 36165519 Hereditary Angioedema is Associated with an Increased Risk of Venous Thromboembolism Journal of Thrombosis and Haemostasis : JTH. Nov, 2022 | Pubmed ID: 36053174 Understanding COVID-19-associated Coagulopathy Nature Reviews. Immunology. Oct, 2022 | Pubmed ID: 35931818 Markers of Neutrophil Activation and Neutrophil Extracellular Traps in Diagnosing Patients with Acute Venous Thromboembolism: A Feasibility Study Based on Two VTE Cohorts PloS One. 2022 | Pubmed ID: 35901107 Measurement of Tissue Factor-positive Extracellular Vesicles in Plasma: Strengths and Weaknesses of Current Methods Current Opinion in Hematology. Sep, 2022 | Pubmed ID: 35852819 Illustrated State-of-the-Art Capsules of the ISTH 2022 Congress Research and Practice in Thrombosis and Haemostasis. Jul, 2022 | Pubmed ID: 35814801 Circulating Tissue Factor-positive Extracellular Vesicles and Their Association with Thrombosis in Different Diseases Immunological Reviews. Nov, 2022 | Pubmed ID: 35708588 Anticoagulant SERPINs: Endogenous Regulators of Hemostasis and Thrombosis Frontiers in Cardiovascular Medicine. 2022 | Pubmed ID: 35592395 Therapeutic Potential of Granulocyte Microvesicles in Sepsis Blood. Apr, 2022 | Pubmed ID: 35420691 Methods for the Identification and Characterization of Extracellular Vesicles in Cardiovascular Studies - from Exosomes to Microvesicles Cardiovascular Research. Mar, 2022 | Pubmed ID: 35325061 Direct Oral Anticoagulants and Coronary Artery Disease Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2022 | Pubmed ID: 35296151 Evaluation of a New Bead-based Assay to Measure Levels of Human Tissue Factor Antigen in Extracellular Vesicles in Plasma Research and Practice in Thrombosis and Haemostasis. Feb, 2022 | Pubmed ID: 35284777 Effect of Combining Aspirin and Rivaroxaban on Atherosclerosis in Mice Atherosclerosis. Mar, 2022 | Pubmed ID: 35183904 Cancer-associated Venous Thromboembolism Nature Reviews. Disease Primers. Feb, 2022 | Pubmed ID: 35177631 Tissue Factor and Its Procoagulant Activity on Cancer-associated Thromboembolism in Pancreatic Cancer: Comment by Mackman Et Al Cancer Science. May, 2022 | Pubmed ID: 35132733 Web of Science's Citation Median Metrics Overcome the Major Constraints of the Journal Impact Factor Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2022 | Pubmed ID: 35109675 Effect of Heparanase Inhibitor on Tissue Factor Overexpression in Platelets and Endothelial Cells Induced by Anti-β2-GPI Antibodies: Comment from Mackman Et Al Journal of Thrombosis and Haemostasis : JTH. Jan, 2022 | Pubmed ID: 34954879 Genetic Deletion of Platelet PAR4 Results in Reduced Thrombosis and Impaired Hemostatic Plug Stability Journal of Thrombosis and Haemostasis : JTH. Feb, 2022 | Pubmed ID: 34689407 Myeloid Protease-Activated Receptor-2 Contributes to Influenza A Virus Pathology in Mice Frontiers in Immunology. 2021 | Pubmed ID: 34925374 Platelet-Mediated NET Release Amplifies Coagulopathy and Drives Lung Pathology During Severe Influenza Infection Frontiers in Immunology. 2021 | Pubmed ID: 34858432 Hemostatic Biomarkers and Venous Thromboembolism Are Associated With Mortality and Response to Chemotherapy in Patients With Pancreatic Cancer Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2021 | Pubmed ID: 34470475 Tissue Factor Expression, Extracellular Vesicles, and Thrombosis After Infection with the Respiratory Viruses Influenza A Virus and Coronavirus Journal of Thrombosis and Haemostasis : JTH. Nov, 2021 | Pubmed ID: 34418279 Tissue Factor and Extracellular Vesicles: Activation of Coagulation and Impact on Survival in Cancer Cancers. Jul, 2021 | Pubmed ID: 34359742 Cell Type-specific Roles of PAR1 in Coxsackievirus B3 Infection Scientific Reports. Jul, 2021 | Pubmed ID: 34253819 Cardiac Tissue Factor Regulates Inflammation, Hypertrophy, and Heart Failure in Mouse Model of Type 1 Diabetes Diabetes. Sep, 2021 | Pubmed ID: 34155039 Inflammasome Activation Promotes Venous Thrombosis Through Pyroptosis Blood Advances. Jun, 2021 | Pubmed ID: 34152402 Soluble Angiotensin-converting Enzyme 2 is Transiently Elevated in COVID-19 and Correlates with Specific Inflammatory and Endothelial Markers Journal of Medical Virology. Oct, 2021 | Pubmed ID: 34138483 Myeloid Cell-derived Coagulation Tissue Factor is Associated with Renal Tubular Damage in Mice Fed an Adenine Diet Scientific Reports. Jun, 2021 | Pubmed ID: 34108522 Comparison of the Coagulopathies Associated with COVID-19 and Sepsis Research and Practice in Thrombosis and Haemostasis. May, 2021 | Pubmed ID: 34027292 Effects of Storage and Leukocyte Reduction on the Concentration and Procoagulant Activity of Extracellular Vesicles in Canine Packed Red Cells Journal of Veterinary Emergency and Critical Care (San Antonio, Tex. : 2001). Mar, 2021 | Pubmed ID: 33751799 COVID-19 is Associated with an Acquired Factor XIII Deficiency Thrombosis and Haemostasis. Dec, 2021 | Pubmed ID: 33742434 Glioblastoma Cell Populations with Distinct Oncogenic Programs Release Podoplanin As Procoagulant Extracellular Vesicles Blood Advances. Mar, 2021 | Pubmed ID: 33720339 Prognostic Value of Circulating Markers of Neutrophil Activation, Neutrophil Extracellular Traps, Coagulation and Fibrinolysis in Patients with Terminal Cancer Scientific Reports. Mar, 2021 | Pubmed ID: 33658563 Platelets and Viruses Platelets. Apr, 2021 | Pubmed ID: 33615982 Cancer Therapy-Associated Thrombosis Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2021 | Pubmed ID: 33567864 Sustained Prothrombotic Changes in COVID-19 Patients 4 Months After Hospital Discharge Blood Advances. Feb, 2021 | Pubmed ID: 33560386 Prothrombotic Changes in Patients with COVID-19 Are Associated with Disease Severity and Mortality Research and Practice in Thrombosis and Haemostasis. Jan, 2021 | Pubmed ID: 33537537 Natural IgM Antibodies Inhibit Microvesicle-driven Coagulation and Thrombosis Blood. Mar, 2021 | Pubmed ID: 33512411 The Intrinsic Pathway Does Not Contribute to Activation of Coagulation in Mice Bearing Human Pancreatic Tumors Expressing Tissue Factor Thrombosis and Haemostasis. Jul, 2021 | Pubmed ID: 33498089 Plasminogen Activator Inhibitor 1 and Venous Thrombosis in Pancreatic Cancer Blood Advances. Jan, 2021 | Pubmed ID: 33496742 Elevated Factor V Activity and Antigen Levels in Patients with Covid-19 Are Related to Disease Severity and 30-day Mortality American Journal of Hematology. Apr, 2021 | Pubmed ID: 33393103 New Cellular Source of TF (Tissue Factor)-Positive Extracellular Vesicles in the Circulation Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2021 | Pubmed ID: 33356372 PAR1 Regulation of CXCL1 Expression and Neutrophil Recruitment to the Lung in Mice Infected with Influenza A Virus Journal of Thrombosis and Haemostasis : JTH. Apr, 2021 | Pubmed ID: 33346953 Circulating Markers of Neutrophil Extracellular Traps Are of Prognostic Value in Patients With COVID-19 Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2021 | Pubmed ID: 33267662 Patients With COVID-19 Have Elevated Levels of Circulating Extracellular Vesicle Tissue Factor Activity That Is Associated With Severity and Mortality-Brief Report Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2021 | Pubmed ID: 33267656 Description of the First Mutation in the Human Tissue Factor Gene Associated with a Bleeding Tendency Journal of Thrombosis and Haemostasis : JTH. Jan, 2021 | Pubmed ID: 33225609 Thrombin-PAR1 Signaling in Pancreatic Cancer Promotes an Immunosuppressive Microenvironment Journal of Thrombosis and Haemostasis : JTH. Jan, 2021 | Pubmed ID: 33064371 Model-dependent Contributions of FXII and FXI to Venous Thrombosis in Mice Journal of Thrombosis and Haemostasis : JTH. Nov, 2020 | Pubmed ID: 33094904 Evaluation of Different Commercial Antibodies for Their Ability to Detect Human and Mouse Tissue Factor by Western Blotting Research and Practice in Thrombosis and Haemostasis. Aug, 2020 | Pubmed ID: 32864552 Tissue Factor in Atherosclerosis and Atherothrombosis Atherosclerosis. Aug, 2020 | Pubmed ID: 32674807 Coagulation Abnormalities and Thrombosis in Patients Infected With SARS-CoV-2 and Other Pandemic Viruses Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2020 | Pubmed ID: 32657623 Quantification of Citrullinated Histones: Development of an Improved Assay to Reliably Quantify Nucleosomal H3Cit in Human Plasma Journal of Thrombosis and Haemostasis : JTH. Oct, 2020 | Pubmed ID: 32654410 Effect of Chemotherapy and Longitudinal Analysis of Circulating Extracellular Vesicle Tissue Factor Activity in Patients with Pancreatic and Colorectal Cancer Research and Practice in Thrombosis and Haemostasis. May, 2020 | Pubmed ID: 32548563 Chemotherapy Increases Stroke: Fact or Fiction? Thrombosis and Haemostasis. Apr, 2020 | Pubmed ID: 32289856 Quantification of Viral and Host Biomarkers in the Liver of Rhesus Macaques: A Longitudinal Study of Zaire Ebolavirus Strain Kikwit (EBOV/Kik) The American Journal of Pathology. Jul, 2020 | Pubmed ID: 32275904 Therapeutic Strategies for Thrombosis: New Targets and Approaches Nature Reviews. Drug Discovery. May, 2020 | Pubmed ID: 32132678 Differential Roles of Factors IX and XI in Murine Placenta and Hemostasis Under Conditions of Low Tissue Factor Blood Advances. Jan, 2020 | Pubmed ID: 31935292 Annual Report on Sex in Preclinical Studies: Publications in 2018 Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2020 | Pubmed ID: 31869272 Plasma Kallikrein Contributes to Coagulation in the Absence of Factor XI by Activating Factor IX Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2020 | Pubmed ID: 31766871 Circulating Extracellular Vesicle Tissue Factor Activity During Orthohantavirus Infection Is Associated With Intravascular Coagulation The Journal of Infectious Diseases. Sep, 2020 | Pubmed ID: 31722433 How Useful Are Ferric Chloride Models of Arterial Thrombosis? Platelets. May, 2020 | Pubmed ID: 31608756 Cell Type-specific Mechanisms Coupling Protease-activated Receptor-1 to Infectious Colitis Pathogenesis Journal of Thrombosis and Haemostasis : JTH. Jan, 2020 | Pubmed ID: 31539206 Neutrophils and Neutrophil Extracellular Traps Enhance Venous Thrombosis in Mice Bearing Human Pancreatic Tumors Haematologica. Jan, 2020 | Pubmed ID: 31048354 Bacterial Endotoxin Activates the Coagulation Cascade Through Gasdermin D-Dependent Phosphatidylserine Exposure Immunity. Dec, 2019 | Pubmed ID: 31836429 Update from the Laboratory: Mechanistic Studies of Pathways of Cancer-associated Venous Thrombosis Using Mouse Models Hematology. American Society of Hematology. Education Program. Dec, 2019 | Pubmed ID: 31808871 Increasing the Sensitivity of the Human Microvesicle Tissue Factor Activity Assay Thrombosis Research. Oct, 2019 | Pubmed ID: 31450010 Rivaroxaban Does Not Affect Growth of Human Pancreatic Tumors in Mice Journal of Thrombosis and Haemostasis : JTH. Dec, 2019 | Pubmed ID: 31393055 Protease-activated Receptor 4 Protects Mice from Coxsackievirus B3 and H1N1 Influenza A Virus Infection Cellular Immunology. Oct, 2019 | Pubmed ID: 31337508 Neutrophil Extracellular Traps: Villains and Targets in Arterial, Venous, and Cancer-Associated Thrombosis Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2019 | Pubmed ID: 31315434 Cancer Cell-derived Tissue Factor-positive Extracellular Vesicles: Biomarkers of Thrombosis and Survival Current Opinion in Hematology. Sep, 2019 | Pubmed ID: 31261175 Mitochondria Are a Subset of Extracellular Vesicles Released by Activated Monocytes and Induce Type I IFN and TNF Responses in Endothelial Cells Circulation Research. Jun, 2019 | Pubmed ID: 31219742 Tissue Factor and Cancer: Regulation, Tumor Growth, and Metastasis Seminars in Thrombosis and Hemostasis. Jun, 2019 | Pubmed ID: 31096306 Inflammasome Activation Triggers Blood Clotting and Host Death Through Pyroptosis Immunity. Jun, 2019 | Pubmed ID: 31076358 Patients with Severe Orthohantavirus Cardiopulmonary Syndrome Due to Sin Nombre Virus Infection Have Increased Circulating Extracellular Vesicle Tissue Factor and an Activated Coagulation System Thrombosis Research. Jul, 2019 | Pubmed ID: 31075699 Expression of Factor V by Resident Macrophages Boosts Host Defense in the Peritoneal Cavity The Journal of Experimental Medicine. 06, 2019 | Pubmed ID: 31048328 Choosing a Mouse Model of Venous Thrombosis: a Consensus Assessment of Utility and Application Journal of Thrombosis and Haemostasis : JTH. Apr, 2019 | Pubmed ID: 30927321 Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice Scientific Reports. 03, 2019 | Pubmed ID: 30846818 Choosing a Mouse Model of Venous Thrombosis Arteriosclerosis, Thrombosis, and Vascular Biology. 03, 2019 | Pubmed ID: 30786739 A Clinical Practice-based Evaluation of the RIETE Score in Predicting Occult Cancer in Patients with Venous Thromboembolism Journal of Thrombosis and Thrombolysis. Jul, 2019 | Pubmed ID: 30739306 Intrinsic Pathway of Coagulation and Thrombosis Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2019 | Pubmed ID: 30700128 Measurement of Tissue Factor Activity in Extracellular Vesicles from Human Plasma Samples Research and Practice in Thrombosis and Haemostasis. Jan, 2019 | Pubmed ID: 30656275 Roles of Coagulation Proteases and PARs (Protease-Activated Receptors) in Mouse Models of Inflammatory Diseases Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2019 | Pubmed ID: 30580574 MTOR Kinase Inhibition Reduces Tissue Factor Expression and Growth of Pancreatic Neuroendocrine Tumors Journal of Thrombosis and Haemostasis : JTH. Jan, 2019 | Pubmed ID: 30472780 Low Extracellular Vesicle-associated Tissue Factor Activity in Patients with Persistent Lupus Anticoagulant and a History of Thrombosis Annals of Hematology. Feb, 2019 | Pubmed ID: 30467688 Reporting Sex and Sex Differences in Preclinical Studies Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2018 | Pubmed ID: 30354222 Neutrophils, NETs, and Immunothrombosis Blood. Sep, 2018 | Pubmed ID: 30262582 Protease-activated Receptor 1 Activation Enhances Doxorubicin-induced Cardiotoxicity Journal of Molecular and Cellular Cardiology. Sep, 2018 | Pubmed ID: 30098988 The Uremic Solute-AHR-tissue Factor Axis in Vascular Cells, Mouse Models and Thrombosis in Chronic Kidney Disease Patients Annals of Translational Medicine. Jun, 2018 | Pubmed ID: 30023388 The Factor Xa Inhibitor Rivaroxaban Reduces Cardiac Dysfunction in a Mouse Model of Myocardial Infarction Thrombosis Research. Jul, 2018 | Pubmed ID: 29843086 Response by Daugherty Et Al to Letter Regarding Article, "Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies: A Statement From the Council" Arteriosclerosis, Thrombosis, and Vascular Biology. Jun, 2018 | Pubmed ID: 29793996 Tissue Factor and Oxidative Stress Blood. May, 2018 | Pubmed ID: 29748170 Extracellular Vesicles Exposing Tissue Factor for the Prediction of Venous Thromboembolism in Patients with Cancer: A Prospective Cohort Study Thrombosis Research. Jun, 2018 | Pubmed ID: 29656167 PAR2 (Protease-Activated Receptor 2) Deficiency Attenuates Atherosclerosis in Mice Arteriosclerosis, Thrombosis, and Vascular Biology. 06, 2018 | Pubmed ID: 29599135 Platelet Signaling Pathways and New Inhibitors Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2018 | Pubmed ID: 29563117 Comparison of Microvesicle Tissue Factor Activity in Non-cancer Severely Ill Patients and Cancer Patients Thrombosis Research. May, 2018 | Pubmed ID: 29539580 Dual Anticoagulant and Antiplatelet Therapy for Coronary Artery Disease and Peripheral Artery Disease Patients Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2018 | Pubmed ID: 29449336 Tissue Factor: An Essential Mediator of Hemostasis and Trigger of Thrombosis Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2018 | Pubmed ID: 29437578 Distinct Pathogenesis of Pancreatic Cancer Microvesicle-Associated Venous Thrombosis Identifies New Antithrombotic Targets In Vivo Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2018 | Pubmed ID: 29419408 Association of D-dimer with Plaque Characteristics and Plasma Biomarkers of Oxidation-Specific Epitopes in Stable Subjects with Coronary Artery Disease Journal of Cardiovascular Translational Research. 06, 2018 | Pubmed ID: 29344841 Mouse Models of Cancer-associated Thrombosis Thrombosis Research. Apr, 2018 | Pubmed ID: 29306575 Caspase Inhibition Reduces Hepatic Tissue Factor-Driven Coagulation In Vitro and In Vivo Toxicological Sciences : an Official Journal of the Society of Toxicology. Apr, 2018 | Pubmed ID: 29228388 Cancer-associated Pathways and Biomarkers of Venous Thrombosis Blood. Sep, 2017 | Pubmed ID: 28807983 Thrombin Promotes Diet-induced Obesity Through Fibrin-driven Inflammation The Journal of Clinical Investigation. Aug, 2017 | Pubmed ID: 28737512 A Monocyte-TNF-endothelial Activation Axis in Sickle Transgenic Mice: Therapeutic Benefit from TNF Blockade American Journal of Hematology. Nov, 2017 | Pubmed ID: 28699284 Methodological Guidelines to Study Extracellular Vesicles Circulation Research. May, 2017 | Pubmed ID: 28495994 Detection of Tissue Factor-positive Extracellular Vesicles by Laser Scanning Confocal Microscopy Thrombosis Research. Feb, 2017 | Pubmed ID: 28043041 Tissue Factor: Catch Me If You Can! Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Apr, 2017 | Pubmed ID: 28029321 Erratum to "A Combined Deficiency of Tissue Factor and PAR-4 is Associated with Fatal Pulmonary Hemorrhage in Mice" [Thromb. Res. 146 (2016) 46-50] Thrombosis Research. Jan, 2017 | Pubmed ID: 27890308 Protease-Activated Receptor 1 Contributes to Angiotensin II-Induced Cardiovascular Remodeling and Inflammation Cardiology. 2017 | Pubmed ID: 27880950 Protease-Activated Receptor 1 Enhances Poly I:C Induction of the Antiviral Response in Macrophages and Mice Journal of Innate Immunity. 2017 | Pubmed ID: 27820939 Letter to Editor Response: Endothelial Cell Tissue Factor and Coagulation Trends in Cardiovascular Medicine. Feb, 2017 | Pubmed ID: 27769630 Anticoagulation Increases Alveolar Hemorrhage in Mice Infected with Influenza A Physiological Reports. Dec, 2016 | Pubmed ID: 28003564 Corrigendum to "Measurement of Microparticle Tissue Factor Activity in Clinical Samples: A Summary of Two Tissue Factor-dependent FXa Generation Assays" [Thromb. Res. 139 (2016) 90-97] Thrombosis Research. 11, 2016 | Pubmed ID: 27676256 Corrigendum to 'Microvesicle-associated Tissue Factor Procoagulant Activity for the Preoperative Diagnosis of Ovarian Cancer", [Thromb. Res. 141 (2016) 39-48] Thrombosis Research. Oct, 2016 | Pubmed ID: 27640329 A Combined Deficiency of Tissue Factor and PAR-4 is Associated with Fatal Pulmonary Hemorrhage in Mice Thrombosis Research. Oct, 2016 | Pubmed ID: 27586081 Thrombosis in Cancer: Research Priorities Identified by a National Cancer Institute/National Heart, Lung, and Blood Institute Strategic Working Group Cancer Research. Jul, 2016 | Pubmed ID: 27527638 Protective and Detrimental Effects of Neuroectodermal Cell-derived Tissue Factor in Mouse Models of Stroke JCI Insight. Jul, 2016 | Pubmed ID: 27489885 Complying With the National Institutes of Health Guidelines and Principles for Rigor and Reproducibility: Refutations Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2016 | Pubmed ID: 27335467 Mouse Models of Venous Thrombosis Are Not Equal Blood. May, 2016 | Pubmed ID: 27231393 CalDAG-GEFI Deficiency Reduces Atherosclerotic Lesion Development in Mice Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2016 | Pubmed ID: 26988592 Microvesicle-associated Tissue Factor Procoagulant Activity for the Preoperative Diagnosis of Ovarian Cancer Thrombosis Research. May, 2016 | Pubmed ID: 26967531 Antibody-based Targeting of Alternatively Spliced Tissue Factor: a New Approach to Impede the Primary Growth and Spread of Pancreatic Ductal Adenocarcinoma Oncotarget. May, 2016 | Pubmed ID: 26967388 Tissue Factor Deficiency Increases Alveolar Hemorrhage and Death in Influenza A Virus-infected Mice Journal of Thrombosis and Haemostasis : JTH. Jun, 2016 | Pubmed ID: 26947929 Myeloid Tissue Factor Does Not Modulate Lung Inflammation or Permeability During Experimental Acute Lung Injury Scientific Reports. Feb, 2016 | Pubmed ID: 26924425 Measurement of Microparticle Tissue Factor Activity in Clinical Samples: A Summary of Two Tissue Factor-dependent FXa Generation Assays Thrombosis Research. 03, 2016 | Pubmed ID: 26916302 The Clot Thickens in Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2016 | Pubmed ID: 26912742 Editorial Commentary: Tissue Factor Expression by the Endothelium: Coagulation or Inflammation? Trends in Cardiovascular Medicine. May, 2016 | Pubmed ID: 26850939 Thrombin-independent Contribution of Tissue Factor to Inflammation and Cardiac Hypertrophy in a Mouse Model of Sickle Cell Disease Blood. Mar, 2016 | Pubmed ID: 26817955 Microvesicle Tissue Factor Activity and Interleukin-8 Levels Are Associated with Mortality in Patients with Influenza A/H1N1 Infection Critical Care Medicine. Jul, 2016 | Pubmed ID: 26751613 IL-13 Augments Compressive Stress-Induced Tissue Factor Expression in Human Airway Epithelial Cells American Journal of Respiratory Cell and Molecular Biology. Apr, 2016 | Pubmed ID: 26407210 Hepatocyte Tissue Factor Contributes to the Hypercoagulable State in a Mouse Model of Chronic Liver Injury Journal of Hepatology. Jan, 2016 | Pubmed ID: 26325534 Venous Thrombosis Nature Reviews. Disease Primers. May, 2015 | Pubmed ID: 27189130 Theme 2: Epidemiology, Biomarkers, and Imaging of Venous Thromboembolism (and Postthrombotic Syndrome) Thrombosis Research. Sep, 2015 | Pubmed ID: 26387734 Platelet Inhibitors Reduce Rupture in a Mouse Model of Established Abdominal Aortic Aneurysm Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2015 | Pubmed ID: 26139462 Tissue Factor and Atherothrombosis Journal of Atherosclerosis and Thrombosis. 2015 | Pubmed ID: 26016513 A Matched Cross-sectional Study of the Association Between Circulating Tissue Factor Activity, Immune Activation and Advanced Liver Fibrosis in Hepatitis C Infection BMC Infectious Diseases. Apr, 2015 | Pubmed ID: 25884329 Extracellular Vesicles, Tissue Factor, Cancer and Thrombosis - Discussion Themes of the ISEV 2014 Educational Day Journal of Extracellular Vesicles. 2015 | Pubmed ID: 25773446 RASA3 is a Critical Inhibitor of RAP1-dependent Platelet Activation The Journal of Clinical Investigation. Apr, 2015 | Pubmed ID: 25705885 Excess of Heme Induces Tissue Factor-dependent Activation of Coagulation in Mice Haematologica. Mar, 2015 | Pubmed ID: 25596265 Protective and Pathological Roles of Tissue Factor in the Heart Hamostaseologie. 2015 | Pubmed ID: 25434707 Reduced Thrombosis in Klkb1-/- Mice is Mediated by Increased Mas Receptor, Prostacyclin, Sirt1, and KLF4 and Decreased Tissue Factor Blood. Jan, 2015 | Pubmed ID: 25339356 Role of Tissue Factor in Mycobacterium Tuberculosis-induced Inflammation and Disease Pathogenesis PloS One. 2014 | Pubmed ID: 25462128 PARP-14 Combines with Tristetraprolin in the Selective Posttranscriptional Control of Macrophage Tissue Factor Expression Blood. Dec, 2014 | Pubmed ID: 25293769 Inactivation of Factor VIIa by Antithrombin in Vitro, Ex Vivo and in Vivo: Role of Tissue Factor and Endothelial Cell Protein C Receptor PloS One. 2014 | Pubmed ID: 25102166 New Targets for Atherothrombosis Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2014 | Pubmed ID: 25031326 Fas-induced Apoptosis Increases Hepatocyte Tissue Factor Procoagulant Activity in Vitro and in Vivo Toxicological Sciences : an Official Journal of the Society of Toxicology. Oct, 2014 | Pubmed ID: 25015658 Factor XIII Activity Mediates Red Blood Cell Retention in Venous Thrombi The Journal of Clinical Investigation. Aug, 2014 | Pubmed ID: 24983320 Regulation of Tissue Factor Gene Expression in Monocytes and Endothelial Cells: Thromboxane A2 As a New Player Vascular Pharmacology. Aug, 2014 | Pubmed ID: 24858575 Roles of PAR1 and PAR2 in Viral Myocarditis Thrombosis Research. May, 2014 | Pubmed ID: 24759133 Multiple Roles of the Coagulation Protease Cascade During Virus Infection Blood. Apr, 2014 | Pubmed ID: 24632711 Tissue Factor Expression Provokes Escape from Tumor Dormancy and Leads to Genomic Alterations Proceedings of the National Academy of Sciences of the United States of America. Mar, 2014 | Pubmed ID: 24520174 Circulating Microparticle Tissue Factor Activity is Increased in Patients with Cirrhosis Hepatology (Baltimore, Md.). Nov, 2014 | Pubmed ID: 24470301 Differential Contribution of FXa and Thrombin to Vascular Inflammation in a Mouse Model of Sickle Cell Disease Blood. Mar, 2014 | Pubmed ID: 24449213 The Antithrombotic Effects of Statins Annual Review of Medicine. 2014 | Pubmed ID: 24422578 Coagulation, Protease-activated Receptors, and Viral Myocarditis Journal of Cardiovascular Translational Research. Mar, 2014 | Pubmed ID: 24203054 Hyperlipidemia, Tissue Factor, Coagulation, and Simvastatin Trends in Cardiovascular Medicine. Apr, 2014 | Pubmed ID: 24016468 Protease Activated Receptor-2 Contributes to Heart Failure PloS One. 2013 | Pubmed ID: 24312345 PAR-1 Contributes to the Innate Immune Response During Viral Infection The Journal of Clinical Investigation. Mar, 2013 | Pubmed ID: 23391721 Microvesicles As Risk Markers for Venous Thrombosis Expert Review of Hematology. Feb, 2013 | Pubmed ID: 23373784 Platelet ITAM Signaling is Critical for Vascular Integrity in Inflammation The Journal of Clinical Investigation. Feb, 2013 | Pubmed ID: 23348738 Hepatocyte Tissue Factor Activates the Coagulation Cascade in Mice Blood. Mar, 2013 | Pubmed ID: 23305736 Role of Tissue Factor in Atherothrombosis Current Atherosclerosis Reports. Oct, 2012 | Pubmed ID: 22886473 Dysregulated Coagulation Associated with Hypofibrinogenaemia and Plasma Hypercoagulability: Implications for Identifying Coagulopathic Mechanisms in Humans Thrombosis and Haemostasis. Sep, 2012 | Pubmed ID: 22836883 P2X7 Regulation of Macrophage Tissue Factor Activity and Microparticle Generation Journal of Thrombosis and Haemostasis : JTH. Sep, 2012 | Pubmed ID: 22759201 New Insights into the Mechanisms of Venous Thrombosis The Journal of Clinical Investigation. Jul, 2012 | Pubmed ID: 22751108 Tissue Factor Promotes Activation of Coagulation and Inflammation in a Mouse Model of Sickle Cell Disease Blood. Jul, 2012 | Pubmed ID: 22661702 β-adrenergic Receptor Stimulation Transactivates Protease-activated Receptor 1 Via Matrix Metalloproteinase 13 in Cardiac Cells Circulation. Jun, 2012 | Pubmed ID: 22610965 Tumor-derived Tissue Factor Activates Coagulation and Enhances Thrombosis in a Mouse Xenograft Model of Human Pancreatic Cancer Blood. Jun, 2012 | Pubmed ID: 22547577 Monocytes, Neutrophils, and Platelets Cooperate to Initiate and Propagate Venous Thrombosis in Mice in Vivo The Journal of Experimental Medicine. Apr, 2012 | Pubmed ID: 22451716 Sources of Tissue Factor That Contribute to Thrombosis After Rupture of an Atherosclerotic Plaque Thrombosis Research. May, 2012 | Pubmed ID: 22444158 PF4/heparin-antibody Complex Induces Monocyte Tissue Factor Expression and Release of Tissue Factor Positive Microparticles by Activation of FcγRI Blood. May, 2012 | Pubmed ID: 22394597 Mouse Models, Risk Factors, and Treatments of Venous Thrombosis Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2012 | Pubmed ID: 22345592 Monocyte Tissue Factor-dependent Activation of Coagulation in Hypercholesterolemic Mice and Monkeys is Inhibited by Simvastatin The Journal of Clinical Investigation. Feb, 2012 | Pubmed ID: 22214850 Tissue Factor in Health and Disease Frontiers in Bioscience (Elite Edition). Jan, 2012 | Pubmed ID: 22201878 Defining MAP3 Kinases Required for MDA-MB-231 Cell Tumor Growth and Metastasis Oncogene. Aug, 2012 | Pubmed ID: 22139075 Anthracycline Treatment of the Human Monocytic Leukemia Cell Line THP-1 Increases Phosphatidylserine Exposure and Tissue Factor Activity Thrombosis Research. Feb, 2012 | Pubmed ID: 21762960 Myeloid Cell Tissue Factor Does Not Contribute to Venous Thrombogenesis in an Electrolytic Injury Model Thrombosis Research. Dec, 2011 | Pubmed ID: 22192154 Effect of PAR-2 Deficiency in Mice on KC Expression After Intratracheal LPS Administration Journal of Signal Transduction. 2011 | Pubmed ID: 22175012 Comment on "tissue Factor-dependent Chemokine Production Aggravates Experimental Colitis" Molecular Medicine (Cambridge, Mass.). 2011 | Pubmed ID: 22027905 Blood Coagulation and Blood Vessel Development: is Tissue Factor the Missing Link? Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2011 | Pubmed ID: 22011746 Protease-activated Receptor 1 and Hematopoietic Cell Tissue Factor Are Required for Hepatic Steatosis in Mice Fed a Western Diet The American Journal of Pathology. Nov, 2011 | Pubmed ID: 21907177 Regulation of Thrombin-induced Plasminogen Activator Inhibitor-1 in 4T1 Murine Breast Cancer Cells Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis. Oct, 2011 | Pubmed ID: 21799402 Monocytic Microparticles Activate Endothelial Cells in an IL-1β-dependent Manner Blood. Aug, 2011 | Pubmed ID: 21700772 Microparticles in Hemostasis and Thrombosis Circulation Research. May, 2011 | Pubmed ID: 21566224 Protease-activated Receptors and Myocardial Infarction IUBMB Life. Jun, 2011 | Pubmed ID: 21438116 MPs or ICs? Blood. Jan, 2011 | Pubmed ID: 21273325 Tissue Factor and Tissue Factor Pathway Inhibitor As Key Regulators of Global Hemostasis: Measurement of Their Levels in Coagulation Assays Seminars in Thrombosis and Hemostasis. Oct, 2010 | Pubmed ID: 20978997 Balancing Clotting Blood. Sep, 2010 | Pubmed ID: 20829379 Protease-activated Receptors Mediate Crosstalk Between Coagulation and Fibrinolysis Blood. Dec, 2010 | Pubmed ID: 20736455 Protease-activated Receptor 2 Deficiency Reduces Cardiac Ischemia/reperfusion Injury Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2010 | Pubmed ID: 20724699 Elevated Tissue Factor Expression Contributes to Exacerbated Diabetic Nephropathy in Mice Lacking ENOS Fed a High Fat Diet Journal of Thrombosis and Haemostasis : JTH. Oct, 2010 | Pubmed ID: 20626618 Tissue Factor and Thrombosis: The Clot Starts Here Thrombosis and Haemostasis. Sep, 2010 | Pubmed ID: 20539911 Hematopoietic and Nonhematopoietic Cell Tissue Factor Activates the Coagulation Cascade in Endotoxemic Mice Blood. Aug, 2010 | Pubmed ID: 20410508 Venous Thromboembolism in Multiple Myeloma: Current Perspectives in Pathogenesis European Journal of Cancer (Oxford, England : 1990). Jul, 2010 | Pubmed ID: 20385482 Cellular Sources of Tissue Factor in Endotoxemia and Sepsis Thrombosis Research. Apr, 2010 | Pubmed ID: 20185165 Wound Healing in Hemophilia B Mice and Low Tissue Factor Mice Thrombosis Research. Apr, 2010 | Pubmed ID: 20170942 DVT: a New Era in Anticoagulant Therapy Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2010 | Pubmed ID: 20139354 Increased Microparticle Tissue Factor Activity in Cancer Patients with Venous Thromboembolism Thrombosis Research. Jun, 2010 | Pubmed ID: 19854471 Detection of Endogenous Tissue Factor Levels in Plasma Using the Calibrated Automated Thrombogram Assay Thrombosis Research. Jan, 2010 | Pubmed ID: 19345399 Tissue Factor: Past, Present, and Future Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2009 | Pubmed ID: 19923557 Role of Tissue Factor in Cancer Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2009 | Pubmed ID: 19738116 On the Trail of Microparticles Circulation Research. Apr, 2009 | Pubmed ID: 19390059 The Role of Tissue Factor and Factor VIIa in Hemostasis Anesthesia and Analgesia. May, 2009 | Pubmed ID: 19372318 Venous Thromboembolism: Risk Factors, Biomarkers, and Treatment Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2009 | Pubmed ID: 19228601 Cardiovascular Disease in Women Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2009 | Pubmed ID: 19221202 Bleeding Hearts Blood. Jan, 2009 | Pubmed ID: 19147791 Vascular Smooth Muscle-derived Tissue Factor is Critical for Arterial Thrombosis After Ferric Chloride-induced Injury Blood. Jan, 2009 | Pubmed ID: 18931346 Tissue Factor Regulation by Epidermal Growth Factor Receptor and Epithelial-to-mesenchymal Transitions: Effect on Tumor Initiation and Angiogenesis Cancer Research. Dec, 2008 | Pubmed ID: 19074872 Tissue Factor and Factor VIIa: Understanding the Molecular Mechanism Thrombosis Research. 2008 | Pubmed ID: 18691490 Tissue-specific Hemostasis: Role of Tissue Factor Journal of Thrombosis and Haemostasis : JTH. Feb, 2008 | Pubmed ID: 18088348 High-Sensitivity Tissue Factor Activity Assay for Plasma Diagnosis (Video) | JoVE Yohei Hisada1, Nigel Mackman1 1Division of Hematology, UNC Blood Research Center, University of North Carolina at Chapel Hill JoVE 65840 Medicine
High-Sensitivity Tissue Factor Activity Assay for Plasma Diagnosis (Video) | JoVE Yohei Hisada1, Nigel Mackman1 1Division of Hematology, UNC Blood Research Center, University of North Carolina at Chapel Hill JoVE 65840 Medicine
