Olaf Kutsch Department of Medicine University of Alabama at Birmingham Biography Publications Institution JoVE Articles Olaf Kutsch has not added a biography. If you are Olaf Kutsch and would like to personalize this page please email our Author Liaison for assistance. Publications Mycobacterium Tuberculosis Exploits the PPM1A Signaling Pathway to Block Host Macrophage Apoptosis Scientific Reports. Feb, 2017 | Pubmed ID: 28176854 8-Hydroxyquinolines Are Boosting Agents of Copper-Related Toxicity in Mycobacterium Tuberculosis Antimicrobial Agents and Chemotherapy. Oct, 2016 | Pubmed ID: 27431227 A Macrophage Infection Model to Predict Drug Efficacy Against Mycobacterium Tuberculosis Assay and Drug Development Technologies. Aug, 2016 | Pubmed ID: 27327048 Protein Phosphatase, Mg2+/Mn2+-dependent 1A Controls the Innate Antiviral and Antibacterial Response of Macrophages During HIV-1 and Mycobacterium Tuberculosis Infection Oncotarget. Mar, 2016 | Pubmed ID: 27004401 Combinatorial Phenotypic Screen Uncovers Unrecognized Family of Extended Thiourea Inhibitors with Copper-dependent Anti-staphylococcal Activity Metallomics : Integrated Biometal Science. Apr, 2016 | Pubmed ID: 26935206 Targeting CXCR4/SDF-1 Axis by Lipopolymer Complexes of SiRNA in Acute Myeloid Leukemia Journal of Controlled Release : Official Journal of the Controlled Release Society. Feb, 2016 | Pubmed ID: 26742943 RNAP II Processivity is a Limiting Step for HIV-1 Transcription Independent of Orientation to and Activity of Endogenous Neighboring Promoters Virology. Dec, 2015 | Pubmed ID: 26379089 The Host Cell Side of Latent HIV-1 Infection Oncotarget. Aug, 2015 | Pubmed ID: 26343367 Disulfiram and Copper Ions Kill Mycobacterium Tuberculosis in a Synergistic Manner Antimicrobial Agents and Chemotherapy. Aug, 2015 | Pubmed ID: 26033731 Stable Phenotypic Changes of the Host T Cells Are Essential to the Long-Term Stability of Latent HIV-1 Infection Journal of Virology. Jul, 2015 | Pubmed ID: 25878110 Copper Complexation Screen Reveals Compounds with Potent Antibiotic Properties Against Methicillin-resistant Staphylococcus Aureus Antimicrobial Agents and Chemotherapy. Jul, 2014 | Pubmed ID: 24752262 Kinase Control of Latent HIV-1 Infection: PIM-1 Kinase As a Major Contributor to HIV-1 Reactivation Journal of Virology. Jan, 2014 | Pubmed ID: 24155393 Copper-boosting Compounds: a Novel Concept for Antimycobacterial Drug Discovery Antimicrobial Agents and Chemotherapy. Feb, 2013 | Pubmed ID: 23254420 An AP-1 Binding Site in the Enhancer/core Element of the HIV-1 Promoter Controls the Ability of HIV-1 to Establish Latent Infection Journal of Virology. Feb, 2013 | Pubmed ID: 23236059 Effective Non-viral Delivery of SiRNA to Acute Myeloid Leukemia Cells with Lipid-substituted Polyethylenimines PloS One. 2012 | Pubmed ID: 22952927 Host Factor Transcriptional Regulation Contributes to Preferential Expression of HIV Type 1 in IL-4-producing CD4 T Cells Journal of Immunology (Baltimore, Md. : 1950). Sep, 2012 | Pubmed ID: 22875803 Selected Drugs with Reported Secondary Cell-differentiating Capacity Prime Latent HIV-1 Infection for Reactivation Journal of Virology. Sep, 2012 | Pubmed ID: 22696646 Kinase Control Prevents HIV-1 Reactivation in Spite of High Levels of Induced NF-κB Activity Journal of Virology. Apr, 2012 | Pubmed ID: 22345467 Validating a Firefly Luciferase-based High-throughput Screening Assay for Antimalarial Drug Discovery Assay and Drug Development Technologies. Feb, 2012 | Pubmed ID: 22050430 Facts and Fiction: Cellular Models for High Throughput Screening for HIV-1 Reactivating Drugs Current HIV Research. Dec, 2011 | Pubmed ID: 22211661 Targeted Disruption of the CCR5 Gene in Human Hematopoietic Stem Cells Stimulated by Peptide Nucleic Acids Chemistry & Biology. Sep, 2011 | Pubmed ID: 21944757 Inhibition of Tat-mediated HIV-1 Replication and Neurotoxicity by Novel GSK3-beta Inhibitors Virology. Jun, 2011 | Pubmed ID: 21514616 A Screen to Identify Small Molecule Inhibitors of Protein-protein Interactions in Mycobacteria Assay and Drug Development Technologies. Jun, 2011 | Pubmed ID: 21281130 Suppressor of Cytokine Signaling 3 Inhibits Antiviral IFN-beta Signaling to Enhance HIV-1 Replication in Macrophages Journal of Immunology (Baltimore, Md. : 1950). Aug, 2010 | Pubmed ID: 20631305 Hit-and-run Stimulation: a Novel Concept to Reactivate Latent HIV-1 Infection Without Cytokine Gene Induction Journal of Virology. Sep, 2010 | Pubmed ID: 20538859 Adjusting Transgene Expression Levels in Lymphocytes with a Set of Inducible Promoters The Journal of Gene Medicine. Jun, 2010 | Pubmed ID: 20527043 Effective Activation Alleviates the Replication Block of CCR5-tropic HIV-1 in Chimpanzee CD4+ Lymphocytes Virology. Nov, 2009 | Pubmed ID: 19748647 Determinants of the Establishment of Human Immunodeficiency Virus Type 1 Latency Journal of Virology. Apr, 2009 | Pubmed ID: 19144703 Human Immunodeficiency Virus Type 2 (HIV-2)/HIV-1 Envelope Chimeras Detect High Titers of Broadly Reactive HIV-1 V3-specific Antibodies in Human Plasma Journal of Virology. Feb, 2009 | Pubmed ID: 19019969 The Quality of Chimpanzee T-cell Activation and Simian Immunodeficiency Virus/human Immunodeficiency Virus Susceptibility Achieved Via Antibody-mediated T-cell Receptor/CD3 Stimulation is a Function of the Anti-CD3 Antibody Isotype Journal of Virology. Oct, 2008 | Pubmed ID: 18667496 Optimization of HIV-1 Infectivity Assays BioTechniques. Nov, 2007 | Pubmed ID: 18072587 High Throughput Drug Screening for Human Immunodeficiency Virus Type 1 Reactivating Compounds Assay and Drug Development Technologies. Apr, 2007 | Pubmed ID: 17477827 A High-throughput Drug Screening System for HIV-1 Transcription Inhibitors Journal of Biomolecular Screening. Oct, 2006 | Pubmed ID: 16831859 Nef-mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage That Gave Rise to HIV-1 Cell. Jun, 2006 | Pubmed ID: 16777597 T-cell Line for HIV Drug Screening Using EGFP As a Quantitative Marker of HIV-1 Replication BioTechniques. Jan, 2006 | Pubmed ID: 16454046 Tat Inhibitors, a New Approach: Interview with Olaf Kutsch, Ph.D. Interview by John S. James AIDS Treatment News. Jan, 2005 | Pubmed ID: 15791713 Bis-anthracycline Antibiotics Inhibit Human Immunodeficiency Virus Type 1 Transcription Antimicrobial Agents and Chemotherapy. May, 2004 | Pubmed ID: 15105117 Dynamics of HIV-1 Recombination in Its Natural Target Cells Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 15010526 CD154-CD40-induced Reactivation of Latent HIV-1 Infection Virology. Sep, 2003 | Pubmed ID: 14517079 Direct and Quantitative Single-cell Analysis of Human Immunodeficiency Virus Type 1 Reactivation from Latency Journal of Virology. Sep, 2002 | Pubmed ID: 12163598 Tumor Necrosis Factor-related Apoptosis-inducing Ligand Induces Caspase-dependent Interleukin-8 Expression and Apoptosis in Human Astroglioma Cells Molecular and Cellular Biology. Feb, 2002 | Pubmed ID: 11784850 एक उच्च throughput संगत परख Macrophage passaged के खिलाफ ड्रग प्रभावकारिता का मूल्यांकन करने के लिए Kaitlyn Schaaf1, Samuel R. Smith1, Virginia Hayley1, Olaf Kutsch1, Jim Sun1 1Department of Medicine, University of Alabama at Birmingham Immunology and Infection
एक उच्च throughput संगत परख Macrophage passaged के खिलाफ ड्रग प्रभावकारिता का मूल्यांकन करने के लिए Kaitlyn Schaaf1, Samuel R. Smith1, Virginia Hayley1, Olaf Kutsch1, Jim Sun1 1Department of Medicine, University of Alabama at Birmingham Immunology and Infection