Patrice Delafontaine Department of Medicine/Heart and Vascular Institute Tulane University Biography Publications Institution JoVE Articles Patrice Delafontaine has not added a biography. If you are Patrice Delafontaine and would like to personalize this page please email our Author Liaison for assistance. Publications SM22α (Smooth Muscle Protein 22-α) Promoter-Driven IGF1R (Insulin-Like Growth Factor 1 Receptor) Deficiency Promotes Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. 10, 2018 | Pubmed ID: 30354209 Rapid Estrogen Receptor-α Signaling Mediated by ERK Activation Regulates Vascular Tone in Male and Ovary-intact Female Mice American Journal of Physiology. Heart and Circulatory Physiology. 02, 2018 | Pubmed ID: 28887333 TRAF3IP2 Mediates Atherosclerotic Plaque Development and Vulnerability in ApoE(-/-) Mice Atherosclerosis. 09, 2016 | Pubmed ID: 27237075 Sodium Excretion and the Risk of Cardiovascular Disease in Patients With Chronic Kidney Disease JAMA. May 24-31, 2016 | Pubmed ID: 27218629 Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E-Deficient Mice Circulation. Jun, 2016 | Pubmed ID: 27154724 TRAF3IP2 Mediates Aldosterone/salt-induced Cardiac Hypertrophy and Fibrosis Molecular and Cellular Endocrinology. 07, 2016 | Pubmed ID: 27040306 The Nox1/4 Dual Inhibitor GKT137831 or Nox4 Knockdown Inhibits Angiotensin-II-Induced Adult Mouse Cardiac Fibroblast Proliferation and Migration. AT1 Physically Associates With Nox4 Journal of Cellular Physiology. May, 2016 | Pubmed ID: 26445208 Kansas City Cardiomyopathy Questionnaire Score Is Associated With Incident Heart Failure Hospitalization in Patients With Chronic Kidney Disease Without Previously Diagnosed Heart Failure: Chronic Renal Insufficiency Cohort Study Circulation. Heart Failure. Jul, 2015 | Pubmed ID: 25985796 Elevation of Cardiovascular Risk by Non-steroidal Anti-inflammatory Drugs Trends in Cardiovascular Medicine. Nov, 2015 | Pubmed ID: 25956433 Insulin-like Growth Factor I Reduces Lipid Oxidation and Foam Cell Formation Via Downregulation of 12/15-lipoxygenase Atherosclerosis. Feb, 2015 | Pubmed ID: 25549319 Digital Plethysmography and Arginine Metabolism in Prehypertension: Effect of Nebivolol Therapy Journal of Clinical Hypertension (Greenwich, Conn.). Jan, 2015 | Pubmed ID: 25495953 Protein Phosphatase 2C-alpha Knockdown Reduces Angiotensin II-mediated Skeletal Muscle Wasting Via Restoration of Mitochondrial Recycling and Function Skeletal Muscle. 2014 | Pubmed ID: 25625009 Angiotensin Type 2 Receptor Signaling in Satellite Cells Potentiates Skeletal Muscle Regeneration The Journal of Biological Chemistry. Sep, 2014 | Pubmed ID: 25112871 Pressure Overload Induces IL-18 and IL-18R Expression, but Markedly Suppresses IL-18BP Expression in a Rabbit Model. IL-18 Potentiates TNF-α-induced Cardiomyocyte Death Journal of Molecular and Cellular Cardiology. Oct, 2014 | Pubmed ID: 25108227 Endovascular Stent-graft Repair of Ascending Aortic Dissection with a Commercially Available Thoracic Endograft The Annals of Thoracic Surgery. Aug, 2014 | Pubmed ID: 25087800 Interaction Between Insulin-like Growth Factor-1 and Atherosclerosis and Vascular Aging Frontiers of Hormone Research. 2014 | Pubmed ID: 24943302 Natural Disasters and Myocardial Infarction: the Six Years After Hurricane Katrina Mayo Clinic Proceedings. Apr, 2014 | Pubmed ID: 24656058 Insulin-like Growth Factor-1 Increases Synthesis of Collagen Type I Via Induction of the MRNA-binding Protein LARP6 Expression and Binding to the 5' Stem-loop of COL1a1 and COL1a2 MRNA The Journal of Biological Chemistry. Mar, 2014 | Pubmed ID: 24469459 Docosahexaenoic Acid Reverses Angiotensin II-induced RECK Suppression and Cardiac Fibroblast Migration Cellular Signalling. May, 2014 | Pubmed ID: 24447911 Acetylsalicylic Acid Inhibits IL-18-induced Cardiac Fibroblast Migration Through the Induction of RECK Journal of Cellular Physiology. Jul, 2014 | Pubmed ID: 24265116 Mammographically Detectable Breast Arterial Calcification and Atherosclerosis Cardiology in Review. Mar-Apr, 2014 | Pubmed ID: 23584424 Angiotensin II Inhibits Satellite Cell Proliferation and Prevents Skeletal Muscle Regeneration The Journal of Biological Chemistry. Aug, 2013 | Pubmed ID: 23831688 Coronary Angiographic Significance of Hyperacute ST-T Changes Associated with Regadenoson Stress Proceedings (Baylor University. Medical Center). Jul, 2013 | Pubmed ID: 23814390 Molecular Mechanisms and Signaling Pathways of Angiotensin II-induced Muscle Wasting: Potential Therapeutic Targets for Cardiac Cachexia The International Journal of Biochemistry & Cell Biology. Oct, 2013 | Pubmed ID: 23769949 The Therapeutic Potential of IGF-I in Skeletal Muscle Repair Trends in Endocrinology and Metabolism: TEM. Jun, 2013 | Pubmed ID: 23628587 Preoperative Electrocardiogram in an 89-year-old Man The Journal of the Louisiana State Medical Society : Official Organ of the Louisiana State Medical Society. Jan-Feb, 2013 | Pubmed ID: 23550392 Persistent Giant U Wave Inversion with Anoxic Brain Injury Proceedings (Baylor University. Medical Center). Apr, 2013 | Pubmed ID: 23543982 Interleukin-18 Enhances IL-18R/Nox1 Binding, and Mediates TRAF3IP2-dependent Smooth Muscle Cell Migration. Inhibition by Simvastatin Cellular Signalling. Jun, 2013 | Pubmed ID: 23541442 Advanced Oxidation Protein Products Induce Cardiomyocyte Death Via Nox2/Rac1/superoxide-dependent TRAF3IP2/JNK Signaling Free Radical Biology & Medicine. Jul, 2013 | Pubmed ID: 23453926 Effect of Hurricane Katrina on Chronobiology at Onset of Acute Myocardial Infarction During the Subsequent Three Years The American Journal of Cardiology. Mar, 2013 | Pubmed ID: 23291089 Insulin-like Growth Factor-1 Regulates Glutathione Peroxidase Expression and Activity in Vascular Endothelial Cells: Implications for Atheroprotective Actions of Insulin-like Growth Factor-1 Biochimica Et Biophysica Acta. Mar, 2013 | Pubmed ID: 23261989 Skeletal Muscle Molecular Alterations Precede Whole-muscle Dysfunction in NYHA Class II Heart Failure Patients Clinical Interventions in Aging. 2012 | Pubmed ID: 23204842 Angiotensin II Enhances AT1-Nox1 Binding and Stimulates Arterial Smooth Muscle Cell Migration and Proliferation Through AT1, Nox1, and Interleukin-18 American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2012 | Pubmed ID: 22636674 Aging, Atherosclerosis, and IGF-1 The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Jun, 2012 | Pubmed ID: 22491965 Angiotensin II Infusion Induces Marked Diaphragmatic Skeletal Muscle Atrophy PloS One. 2012 | Pubmed ID: 22276172 Angiotensin II Reduces Food Intake by Altering Orexigenic Neuropeptide Expression in the Mouse Hypothalamus Endocrinology. Mar, 2012 | Pubmed ID: 22234465 Effect of Hurricane Katrina on Incidence of Acute Myocardial Infarction in New Orleans Three Years After the Storm The American Journal of Cardiology. Feb, 2012 | Pubmed ID: 22154089 Interleukin-17A Stimulates Cardiac Fibroblast Proliferation and Migration Via Negative Regulation of the Dual-specificity Phosphatase MKP-1/DUSP-1 Cellular Signalling. Feb, 2012 | Pubmed ID: 22037550 β2 Adrenergic Activation Induces the Expression of IL-18 Binding Protein, a Potent Inhibitor of Isoproterenol Induced Cardiomyocyte Hypertrophy in Vitro and Myocardial Hypertrophy in Vivo Journal of Molecular and Cellular Cardiology. Jan, 2012 | Pubmed ID: 22004899 Angiotensin II Upregulates Protein Phosphatase 2Cα and Inhibits AMP-activated Protein Kinase Signaling and Energy Balance Leading to Skeletal Muscle Wasting Hypertension (Dallas, Tex. : 1979). Oct, 2011 | Pubmed ID: 21844485 Angiotensin II, Oxidative Stress and Skeletal Muscle Wasting The American Journal of the Medical Sciences. Aug, 2011 | Pubmed ID: 21747283 Angiotensin II Induced Catabolic Effect and Muscle Atrophy Are Redox Dependent Biochemical and Biophysical Research Communications. Jun, 2011 | Pubmed ID: 21570954 Angiotensin-II Type 1 Receptor and NOX2 Mediate TCF/LEF and CREB Dependent WISP1 Induction and Cardiomyocyte Hypertrophy Journal of Molecular and Cellular Cardiology. Jun, 2011 | Pubmed ID: 21376054 Low Circulating Insulin-like Growth Factor I Increases Atherosclerosis in ApoE-deficient Mice American Journal of Physiology. Heart and Circulatory Physiology. May, 2011 | Pubmed ID: 21335474 Interleukin-18/WNT1-inducible Signaling Pathway Protein-1 Signaling Mediates Human Saphenous Vein Smooth Muscle Cell Proliferation Journal of Cellular Physiology. Dec, 2011 | Pubmed ID: 21321938 The Effect of Nebivolol Versus Metoprolol Succinate Extended Release on Asymmetric Dimethylarginine in Hypertension Journal of the American Society of Hypertension : JASH. May-Jun, 2011 | Pubmed ID: 21251896 Symptoms Characteristic of Heart Failure Among CKD Patients Without Diagnosed Heart Failure Journal of Cardiac Failure. Jan, 2011 | Pubmed ID: 21187260 Thiazolidinediones Up-regulate Insulin-like Growth Factor-1 Receptor Via a Peroxisome Proliferator-activated Receptor Gamma-independent Pathway The Journal of Biological Chemistry. Nov, 2010 | Pubmed ID: 20843793 Interleukin-18 Induces EMMPRIN Expression in Primary Cardiomyocytes Via JNK/Sp1 Signaling and MMP-9 in Part Via EMMPRIN and Through AP-1 and NF-kappaB Activation American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2010 | Pubmed ID: 20693392 Smooth Muscle Cell-specific Insulin-like Growth Factor-1 Overexpression in Apoe-/- Mice Does Not Alter Atherosclerotic Plaque Burden but Increases Features of Plaque Stability Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2010 | Pubmed ID: 20671230 EMMPRIN Activates Multiple Transcription Factors in Cardiomyocytes, and Induces Interleukin-18 Expression Via Rac1-dependent PI3K/Akt/IKK/NF-kappaB AndMKK7/JNK/AP-1 Signaling Journal of Molecular and Cellular Cardiology. Oct, 2010 | Pubmed ID: 20538003 IGF-1 Prevents ANG II-induced Skeletal Muscle Atrophy Via Akt- and Foxo-dependent Inhibition of the Ubiquitin Ligase Atrogin-1 Expression American Journal of Physiology. Heart and Circulatory Physiology. May, 2010 | Pubmed ID: 20228261 Vitamin C and Percutaneous Coronary Intervention JACC. Cardiovascular Interventions. Feb, 2010 | Pubmed ID: 20170882 WNT1-inducible Signaling Pathway Protein-1 Activates Diverse Cell Survival Pathways and Blocks Doxorubicin-induced Cardiomyocyte Death Cellular Signalling. May, 2010 | Pubmed ID: 20074638 IGF-1, Oxidative Stress and Atheroprotection Trends in Endocrinology and Metabolism: TEM. Apr, 2010 | Pubmed ID: 20071192 Growth Hormone-releasing Peptide-2 Suppresses Vascular Oxidative Stress in ApoE-/- Mice but Does Not Reduce Atherosclerosis Endocrinology. Dec, 2009 | Pubmed ID: 19819949 Effect of Hurricane Katrina on the Incidence of Acute Coronary Syndrome at a Primary Angioplasty Center in New Orleans Disaster Medicine and Public Health Preparedness. Oct, 2009 | Pubmed ID: 19713855 Intravenous HMSCs Improve Myocardial Infarction in Mice Because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6 Cell Stem Cell. Jul, 2009 | Pubmed ID: 19570514 Insulin Glargine Reduces Carotid Intimal Hyperplasia After Balloon Catheter Injury in Zucker Fatty Rats Possibly by Reduction in Oxidative Stress Molecular and Cellular Biochemistry. Oct, 2009 | Pubmed ID: 19360379 Calcific Constrictive Pericarditis with Refractory Hypokalemia in a Patient with Gitelman's Syndrome The American Journal of the Medical Sciences. Jan, 2009 | Pubmed ID: 19263512 IL-6 and Serum Amyloid A Synergy Mediates Angiotensin II-induced Muscle Wasting Journal of the American Society of Nephrology : JASN. Mar, 2009 | Pubmed ID: 19158350 The Ubiquitin Ligase Nedd4 Mediates Oxidized Low-density Lipoprotein-induced Downregulation of Insulin-like Growth Factor-1 Receptor American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2008 | Pubmed ID: 18723765 Enhancing Repair of the Mammalian Heart Circulation Research. Jun, 2007 | Pubmed ID: 17525368 Predictors of Left Ventricular Dilatation in Young Adults (from the Bogalusa Heart Study) The American Journal of Cardiology. Nov, 2006 | Pubmed ID: 17056336 Angiotensin II As Candidate of Cardiac Cachexia Current Opinion in Clinical Nutrition and Metabolic Care. May, 2006 | Pubmed ID: 16607120 Angiotensin II Stimulates Transcription of Insulin-like Growth Factor I Receptor in Vascular Smooth Muscle Cells: Role of Nuclear Factor-kappaB Endocrinology. Mar, 2006 | Pubmed ID: 16322063 Endothelial Dysfunction: Its Role in Hypertensive Coronary Disease Current Opinion in Cardiology. Jul, 2005 | Pubmed ID: 15956822 Technique and Imaging for Transthoracic Echocardiography of the Laboratory Pig Echocardiography (Mount Kisco, N.Y.). Jul, 2004 | Pubmed ID: 15209726 Expression, Regulation, and Function of IGF-1, IGF-1R, and IGF-1 Binding Proteins in Blood Vessels Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2004 | Pubmed ID: 14604834 Insulin-like Growth Factor-1 Receptor Activation Inhibits Oxidized LDL-induced Cytochrome C Release and Apoptosis Via the Phosphatidylinositol 3 Kinase/Akt Signaling Pathway Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2003 | Pubmed ID: 14551153 दबाव अधिभार के एक चूहा मॉडल प्रेरित उदारवादी remodeling और सिस्टोलिक रोग के रूप में विपरीत सिस्टोलिक हार्ट फेलियर के खिलाफ Antoine H. Chaanine1, L. Gabriel Navar2, Patrice Delafontaine1,2,3 1Department of Medicine/Heart and Vascular Institute, Tulane University, 2Department of Physiology, Tulane University, 3Department of Pharmacology, Tulane University JoVE 60954 Medicine
दबाव अधिभार के एक चूहा मॉडल प्रेरित उदारवादी remodeling और सिस्टोलिक रोग के रूप में विपरीत सिस्टोलिक हार्ट फेलियर के खिलाफ Antoine H. Chaanine1, L. Gabriel Navar2, Patrice Delafontaine1,2,3 1Department of Medicine/Heart and Vascular Institute, Tulane University, 2Department of Physiology, Tulane University, 3Department of Pharmacology, Tulane University JoVE 60954 Medicine
