Patrice Delafontaine Department of Medicine/Heart and Vascular Institute Tulane University Biography Publications Institution JoVE Articles Patrice Delafontaine has not added a biography. If you are Patrice Delafontaine and would like to personalize this page please email our Author Liaison for assistance. Publications SM22α (Smooth Muscle Protein 22-α) Promoter-Driven IGF1R (Insulin-Like Growth Factor 1 Receptor) Deficiency Promotes Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. 10, 2018 | Pubmed ID: 30354209 Rapid Estrogen Receptor-α Signaling Mediated by ERK Activation Regulates Vascular Tone in Male and Ovary-intact Female Mice American Journal of Physiology. Heart and Circulatory Physiology. 02, 2018 | Pubmed ID: 28887333 TRAF3IP2 Mediates Atherosclerotic Plaque Development and Vulnerability in ApoE(-/-) Mice Atherosclerosis. 09, 2016 | Pubmed ID: 27237075 Sodium Excretion and the Risk of Cardiovascular Disease in Patients With Chronic Kidney Disease JAMA. May 24-31, 2016 | Pubmed ID: 27218629 Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E-Deficient Mice Circulation. Jun, 2016 | Pubmed ID: 27154724 TRAF3IP2 Mediates Aldosterone/salt-induced Cardiac Hypertrophy and Fibrosis Molecular and Cellular Endocrinology. 07, 2016 | Pubmed ID: 27040306 The Nox1/4 Dual Inhibitor GKT137831 or Nox4 Knockdown Inhibits Angiotensin-II-Induced Adult Mouse Cardiac Fibroblast Proliferation and Migration. AT1 Physically Associates With Nox4 Journal of Cellular Physiology. May, 2016 | Pubmed ID: 26445208 Kansas City Cardiomyopathy Questionnaire Score Is Associated With Incident Heart Failure Hospitalization in Patients With Chronic Kidney Disease Without Previously Diagnosed Heart Failure: Chronic Renal Insufficiency Cohort Study Circulation. Heart Failure. Jul, 2015 | Pubmed ID: 25985796 Elevation of Cardiovascular Risk by Non-steroidal Anti-inflammatory Drugs Trends in Cardiovascular Medicine. Nov, 2015 | Pubmed ID: 25956433 Insulin-like Growth Factor I Reduces Lipid Oxidation and Foam Cell Formation Via Downregulation of 12/15-lipoxygenase Atherosclerosis. Feb, 2015 | Pubmed ID: 25549319 Digital Plethysmography and Arginine Metabolism in Prehypertension: Effect of Nebivolol Therapy Journal of Clinical Hypertension (Greenwich, Conn.). Jan, 2015 | Pubmed ID: 25495953 Protein Phosphatase 2C-alpha Knockdown Reduces Angiotensin II-mediated Skeletal Muscle Wasting Via Restoration of Mitochondrial Recycling and Function Skeletal Muscle. 2014 | Pubmed ID: 25625009 Angiotensin Type 2 Receptor Signaling in Satellite Cells Potentiates Skeletal Muscle Regeneration The Journal of Biological Chemistry. Sep, 2014 | Pubmed ID: 25112871 Pressure Overload Induces IL-18 and IL-18R Expression, but Markedly Suppresses IL-18BP Expression in a Rabbit Model. IL-18 Potentiates TNF-α-induced Cardiomyocyte Death Journal of Molecular and Cellular Cardiology. Oct, 2014 | Pubmed ID: 25108227 Endovascular Stent-graft Repair of Ascending Aortic Dissection with a Commercially Available Thoracic Endograft The Annals of Thoracic Surgery. Aug, 2014 | Pubmed ID: 25087800 Interaction Between Insulin-like Growth Factor-1 and Atherosclerosis and Vascular Aging Frontiers of Hormone Research. 2014 | Pubmed ID: 24943302 Natural Disasters and Myocardial Infarction: the Six Years After Hurricane Katrina Mayo Clinic Proceedings. Apr, 2014 | Pubmed ID: 24656058 Insulin-like Growth Factor-1 Increases Synthesis of Collagen Type I Via Induction of the MRNA-binding Protein LARP6 Expression and Binding to the 5' Stem-loop of COL1a1 and COL1a2 MRNA The Journal of Biological Chemistry. Mar, 2014 | Pubmed ID: 24469459 Docosahexaenoic Acid Reverses Angiotensin II-induced RECK Suppression and Cardiac Fibroblast Migration Cellular Signalling. May, 2014 | Pubmed ID: 24447911 Acetylsalicylic Acid Inhibits IL-18-induced Cardiac Fibroblast Migration Through the Induction of RECK Journal of Cellular Physiology. Jul, 2014 | Pubmed ID: 24265116 Mammographically Detectable Breast Arterial Calcification and Atherosclerosis Cardiology in Review. Mar-Apr, 2014 | Pubmed ID: 23584424 Angiotensin II Inhibits Satellite Cell Proliferation and Prevents Skeletal Muscle Regeneration The Journal of Biological Chemistry. Aug, 2013 | Pubmed ID: 23831688 Coronary Angiographic Significance of Hyperacute ST-T Changes Associated with Regadenoson Stress Proceedings (Baylor University. Medical Center). Jul, 2013 | Pubmed ID: 23814390 Molecular Mechanisms and Signaling Pathways of Angiotensin II-induced Muscle Wasting: Potential Therapeutic Targets for Cardiac Cachexia The International Journal of Biochemistry & Cell Biology. Oct, 2013 | Pubmed ID: 23769949 The Therapeutic Potential of IGF-I in Skeletal Muscle Repair Trends in Endocrinology and Metabolism: TEM. Jun, 2013 | Pubmed ID: 23628587 Preoperative Electrocardiogram in an 89-year-old Man The Journal of the Louisiana State Medical Society : Official Organ of the Louisiana State Medical Society. Jan-Feb, 2013 | Pubmed ID: 23550392 Persistent Giant U Wave Inversion with Anoxic Brain Injury Proceedings (Baylor University. Medical Center). Apr, 2013 | Pubmed ID: 23543982 Interleukin-18 Enhances IL-18R/Nox1 Binding, and Mediates TRAF3IP2-dependent Smooth Muscle Cell Migration. Inhibition by Simvastatin Cellular Signalling. Jun, 2013 | Pubmed ID: 23541442 Advanced Oxidation Protein Products Induce Cardiomyocyte Death Via Nox2/Rac1/superoxide-dependent TRAF3IP2/JNK Signaling Free Radical Biology & Medicine. Jul, 2013 | Pubmed ID: 23453926 Effect of Hurricane Katrina on Chronobiology at Onset of Acute Myocardial Infarction During the Subsequent Three Years The American Journal of Cardiology. Mar, 2013 | Pubmed ID: 23291089 Insulin-like Growth Factor-1 Regulates Glutathione Peroxidase Expression and Activity in Vascular Endothelial Cells: Implications for Atheroprotective Actions of Insulin-like Growth Factor-1 Biochimica Et Biophysica Acta. Mar, 2013 | Pubmed ID: 23261989 Skeletal Muscle Molecular Alterations Precede Whole-muscle Dysfunction in NYHA Class II Heart Failure Patients Clinical Interventions in Aging. 2012 | Pubmed ID: 23204842 Angiotensin II Enhances AT1-Nox1 Binding and Stimulates Arterial Smooth Muscle Cell Migration and Proliferation Through AT1, Nox1, and Interleukin-18 American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2012 | Pubmed ID: 22636674 Aging, Atherosclerosis, and IGF-1 The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Jun, 2012 | Pubmed ID: 22491965 Angiotensin II Infusion Induces Marked Diaphragmatic Skeletal Muscle Atrophy PloS One. 2012 | Pubmed ID: 22276172 Angiotensin II Reduces Food Intake by Altering Orexigenic Neuropeptide Expression in the Mouse Hypothalamus Endocrinology. Mar, 2012 | Pubmed ID: 22234465 Effect of Hurricane Katrina on Incidence of Acute Myocardial Infarction in New Orleans Three Years After the Storm The American Journal of Cardiology. Feb, 2012 | Pubmed ID: 22154089 Interleukin-17A Stimulates Cardiac Fibroblast Proliferation and Migration Via Negative Regulation of the Dual-specificity Phosphatase MKP-1/DUSP-1 Cellular Signalling. Feb, 2012 | Pubmed ID: 22037550 β2 Adrenergic Activation Induces the Expression of IL-18 Binding Protein, a Potent Inhibitor of Isoproterenol Induced Cardiomyocyte Hypertrophy in Vitro and Myocardial Hypertrophy in Vivo Journal of Molecular and Cellular Cardiology. Jan, 2012 | Pubmed ID: 22004899 Angiotensin II Upregulates Protein Phosphatase 2Cα and Inhibits AMP-activated Protein Kinase Signaling and Energy Balance Leading to Skeletal Muscle Wasting Hypertension (Dallas, Tex. : 1979). Oct, 2011 | Pubmed ID: 21844485 Angiotensin II, Oxidative Stress and Skeletal Muscle Wasting The American Journal of the Medical Sciences. Aug, 2011 | Pubmed ID: 21747283 Angiotensin II Induced Catabolic Effect and Muscle Atrophy Are Redox Dependent Biochemical and Biophysical Research Communications. Jun, 2011 | Pubmed ID: 21570954 Angiotensin-II Type 1 Receptor and NOX2 Mediate TCF/LEF and CREB Dependent WISP1 Induction and Cardiomyocyte Hypertrophy Journal of Molecular and Cellular Cardiology. Jun, 2011 | Pubmed ID: 21376054 Low Circulating Insulin-like Growth Factor I Increases Atherosclerosis in ApoE-deficient Mice American Journal of Physiology. Heart and Circulatory Physiology. May, 2011 | Pubmed ID: 21335474 Interleukin-18/WNT1-inducible Signaling Pathway Protein-1 Signaling Mediates Human Saphenous Vein Smooth Muscle Cell Proliferation Journal of Cellular Physiology. Dec, 2011 | Pubmed ID: 21321938 The Effect of Nebivolol Versus Metoprolol Succinate Extended Release on Asymmetric Dimethylarginine in Hypertension Journal of the American Society of Hypertension : JASH. May-Jun, 2011 | Pubmed ID: 21251896 Symptoms Characteristic of Heart Failure Among CKD Patients Without Diagnosed Heart Failure Journal of Cardiac Failure. Jan, 2011 | Pubmed ID: 21187260 Thiazolidinediones Up-regulate Insulin-like Growth Factor-1 Receptor Via a Peroxisome Proliferator-activated Receptor Gamma-independent Pathway The Journal of Biological Chemistry. Nov, 2010 | Pubmed ID: 20843793 Interleukin-18 Induces EMMPRIN Expression in Primary Cardiomyocytes Via JNK/Sp1 Signaling and MMP-9 in Part Via EMMPRIN and Through AP-1 and NF-kappaB Activation American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2010 | Pubmed ID: 20693392 Smooth Muscle Cell-specific Insulin-like Growth Factor-1 Overexpression in Apoe-/- Mice Does Not Alter Atherosclerotic Plaque Burden but Increases Features of Plaque Stability Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2010 | Pubmed ID: 20671230 EMMPRIN Activates Multiple Transcription Factors in Cardiomyocytes, and Induces Interleukin-18 Expression Via Rac1-dependent PI3K/Akt/IKK/NF-kappaB AndMKK7/JNK/AP-1 Signaling Journal of Molecular and Cellular Cardiology. Oct, 2010 | Pubmed ID: 20538003 IGF-1 Prevents ANG II-induced Skeletal Muscle Atrophy Via Akt- and Foxo-dependent Inhibition of the Ubiquitin Ligase Atrogin-1 Expression American Journal of Physiology. Heart and Circulatory Physiology. May, 2010 | Pubmed ID: 20228261 Vitamin C and Percutaneous Coronary Intervention JACC. Cardiovascular Interventions. Feb, 2010 | Pubmed ID: 20170882 WNT1-inducible Signaling Pathway Protein-1 Activates Diverse Cell Survival Pathways and Blocks Doxorubicin-induced Cardiomyocyte Death Cellular Signalling. May, 2010 | Pubmed ID: 20074638 IGF-1, Oxidative Stress and Atheroprotection Trends in Endocrinology and Metabolism: TEM. Apr, 2010 | Pubmed ID: 20071192 Growth Hormone-releasing Peptide-2 Suppresses Vascular Oxidative Stress in ApoE-/- Mice but Does Not Reduce Atherosclerosis Endocrinology. Dec, 2009 | Pubmed ID: 19819949 Effect of Hurricane Katrina on the Incidence of Acute Coronary Syndrome at a Primary Angioplasty Center in New Orleans Disaster Medicine and Public Health Preparedness. Oct, 2009 | Pubmed ID: 19713855 Intravenous HMSCs Improve Myocardial Infarction in Mice Because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6 Cell Stem Cell. Jul, 2009 | Pubmed ID: 19570514 Insulin Glargine Reduces Carotid Intimal Hyperplasia After Balloon Catheter Injury in Zucker Fatty Rats Possibly by Reduction in Oxidative Stress Molecular and Cellular Biochemistry. Oct, 2009 | Pubmed ID: 19360379 Calcific Constrictive Pericarditis with Refractory Hypokalemia in a Patient with Gitelman's Syndrome The American Journal of the Medical Sciences. Jan, 2009 | Pubmed ID: 19263512 IL-6 and Serum Amyloid A Synergy Mediates Angiotensin II-induced Muscle Wasting Journal of the American Society of Nephrology : JASN. Mar, 2009 | Pubmed ID: 19158350 The Ubiquitin Ligase Nedd4 Mediates Oxidized Low-density Lipoprotein-induced Downregulation of Insulin-like Growth Factor-1 Receptor American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2008 | Pubmed ID: 18723765 Enhancing Repair of the Mammalian Heart Circulation Research. Jun, 2007 | Pubmed ID: 17525368 Predictors of Left Ventricular Dilatation in Young Adults (from the Bogalusa Heart Study) The American Journal of Cardiology. Nov, 2006 | Pubmed ID: 17056336 Angiotensin II As Candidate of Cardiac Cachexia Current Opinion in Clinical Nutrition and Metabolic Care. May, 2006 | Pubmed ID: 16607120 Angiotensin II Stimulates Transcription of Insulin-like Growth Factor I Receptor in Vascular Smooth Muscle Cells: Role of Nuclear Factor-kappaB Endocrinology. Mar, 2006 | Pubmed ID: 16322063 Endothelial Dysfunction: Its Role in Hypertensive Coronary Disease Current Opinion in Cardiology. Jul, 2005 | Pubmed ID: 15956822 Technique and Imaging for Transthoracic Echocardiography of the Laboratory Pig Echocardiography (Mount Kisco, N.Y.). Jul, 2004 | Pubmed ID: 15209726 Expression, Regulation, and Function of IGF-1, IGF-1R, and IGF-1 Binding Proteins in Blood Vessels Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2004 | Pubmed ID: 14604834 Insulin-like Growth Factor-1 Receptor Activation Inhibits Oxidized LDL-induced Cytochrome C Release and Apoptosis Via the Phosphatidylinositol 3 Kinase/Akt Signaling Pathway Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2003 | Pubmed ID: 14551153 Крыса Модель давления Перегрузки индуцированной умеренной ремоделирования и систолической дисфункции в противоположную систолическую сердечную недостаточность Antoine H. Chaanine1, L. Gabriel Navar2, Patrice Delafontaine1,2,3 1Department of Medicine/Heart and Vascular Institute, Tulane University, 2Department of Physiology, Tulane University, 3Department of Pharmacology, Tulane University JoVE 60954 Medicine
Крыса Модель давления Перегрузки индуцированной умеренной ремоделирования и систолической дисфункции в противоположную систолическую сердечную недостаточность Antoine H. Chaanine1, L. Gabriel Navar2, Patrice Delafontaine1,2,3 1Department of Medicine/Heart and Vascular Institute, Tulane University, 2Department of Physiology, Tulane University, 3Department of Pharmacology, Tulane University JoVE 60954 Medicine
