Patrick Van Dijck

Publications

• Force Nanoscopy of Hydrophobic Interactions in the Fungal Pathogen Candida Glabrata
  ACS Nano. Jan, 2015  |   Pubmed ID: 25621738
• Clinical Implications of Oral Candidiasis: Host Tissue Damage and Disseminated Bacterial Disease
  Infection and Immunity. Feb, 2015  |   Pubmed ID: 25422264
• TREHALOSE-6-PHOSPHATE SYNTHASE 1 is Not the Only Active TPS in Arabidopsis Thaliana
  The Biochemical Journal. Dec, 2014  |   Pubmed ID: 25495218
• In Vivo Candida Glabrata Biofilm Development on Foreign Bodies in a Rat Subcutaneous Model
  The Journal of Antimicrobial Chemotherapy. Nov, 2014  |   Pubmed ID: 25406296
• Oral Administration of the Broad-spectrum Antibiofilm Compound Toremifene Inhibits Candida Albicans and Staphylococcus Aureus Biofilm Formation in Vivo
  Antimicrobial Agents and Chemotherapy. Dec, 2014  |   Pubmed ID: 25288093
• Functional Screening of a CDNA Library from the Desiccation-tolerant Plant Selaginella Lepidophylla in Yeast Mutants Identifies Trehalose Biosynthesis Genes of Plant and Microbial Origin
  Journal of Plant Research. Nov, 2014  |   Pubmed ID: 25246071
• Duplication of a Promiscuous Transcription Factor Drives the Emergence of a New Regulatory Network
  Nature Communications. 2014  |   Pubmed ID: 25204769
• Ascorbic Acid Inhibition of Candida Albicans Hsp90-mediated Morphogenesis Occurs Via the Transcriptional Regulator Upc2
  Eukaryotic Cell. Oct, 2014  |   Pubmed ID: 25084864
• The Desiccation Tolerant Secrets of Selaginella Lepidophylla: What We Have Learned So Far?
  Plant Physiology and Biochemistry : PPB / Société Française De Physiologie Végétale. Jul, 2014  |   Pubmed ID: 24813728
• Fine Tuning of Trehalose Biosynthesis and Hydrolysis As Novel Tools for the Generation of Abiotic Stress Tolerant Plants
  Frontiers in Plant Science. 2014  |   Pubmed ID: 24782885
• Microbial Biofilms--the Coming of Age of a Research Field
  Pathogens and Disease. Apr, 2014  |   Pubmed ID: 24723464
• Trehalose Metabolism in Plants
  The Plant Journal : for Cell and Molecular Biology. Aug, 2014  |   Pubmed ID: 24645920
• Molecular Mechanisms of Antimicrobial Tolerance and Resistance in Bacterial and Fungal Biofilms
  Trends in Microbiology. Jun, 2014  |   Pubmed ID: 24598086
• Microbial Cell Surface Proteins and Secreted Metabolites Involved in Multispecies Biofilms
  Pathogens and Disease. Apr, 2014  |   Pubmed ID: 24376219
• Bioluminescence Imaging of Fungal Biofilm Development in Live Animals
  Methods in Molecular Biology (Clifton, N.J.). 2014  |   Pubmed ID: 24166376
• Towards Non-invasive Monitoring of Pathogen-host Interactions During Candida Albicans Biofilm Formation Using in Vivo Bioluminescence
  Cellular Microbiology. Jan, 2014  |   Pubmed ID: 23962311
• Quantifying the Forces Driving Cell-cell Adhesion in a Fungal Pathogen
  Langmuir : the ACS Journal of Surfaces and Colloids. Nov, 2013  |   Pubmed ID: 24152214
• Single-cell Force Spectroscopy of the Medically Important Staphylococcus Epidermidis-Candida Albicans Interaction
  Nanoscale. Nov, 2013  |   Pubmed ID: 24057018
• Recent Insights into Candida Albicans Biofilm Resistance Mechanisms
  Current Genetics. Nov, 2013  |   Pubmed ID: 23974350
• Relevance of Trehalose in Pathogenicity: Some General Rules, Yet Many Exceptions
  PLoS Pathogens. Aug, 2013  |   Pubmed ID: 23966851
• Mammalian Ribosomal and Chaperone Protein RPS3A Counteracts α-synuclein Aggregation and Toxicity in a Yeast Model System
  The Biochemical Journal. Nov, 2013  |   Pubmed ID: 23924367
• Metabolic Engineering of Kluyveromyces Lactis for L-ascorbic Acid (vitamin C) Biosynthesis
  Microbial Cell Factories. 2013  |   Pubmed ID: 23799937
• Activities of Systemically Administered Echinocandins Against in Vivo Mature Candida Albicans Biofilms Developed in a Rat Subcutaneous Model
  Antimicrobial Agents and Chemotherapy. May, 2013  |   Pubmed ID: 23403433
• Overexpression of the Trehalase Gene AtTRE1 Leads to Increased Drought Stress Tolerance in Arabidopsis and is Involved in Abscisic Acid-induced Stomatal Closure
  Plant Physiology. Mar, 2013  |   Pubmed ID: 23341362
• Redundant and Non-redundant Roles of the Trehalose-6-phosphate Phosphatases in Leaf Growth, Root Hair Specification and Energy-responses in Arabidopsis
  Plant Signaling & Behavior. Mar, 2013  |   Pubmed ID: 23299328
• Single-molecule Imaging and Functional Analysis of Als Adhesins and Mannans During Candida Albicans Morphogenesis
  ACS Nano. Dec, 2012  |   Pubmed ID: 23145462
• The Nonsteroidal Antiinflammatory Drug Diclofenac Potentiates the in Vivo Activity of Caspofungin Against Candida Albicans Biofilms
  The Journal of Infectious Diseases. Dec, 2012  |   Pubmed ID: 22984120
• Loss-of-function Mutations in HINT1 Cause Axonal Neuropathy with Neuromyotonia
  Nature Genetics. Oct, 2012  |   Pubmed ID: 22961002
• Tight Control of Trehalose Content is Required for Efficient Heat-induced Cell Elongation in Candida Albicans
  The Journal of Biological Chemistry. Oct, 2012  |   Pubmed ID: 22952228
• Expansive Evolution of the Trehalose-6-phosphate Phosphatase Gene Family in Arabidopsis
  Plant Physiology. Oct, 2012  |   Pubmed ID: 22855938
• Diversity in Genetic in Vivo Methods for Protein-protein Interaction Studies: from the Yeast Two-hybrid System to the Mammalian Split-luciferase System
  Microbiology and Molecular Biology Reviews : MMBR. Jun, 2012  |   Pubmed ID: 22688816
• The Heat-induced Molecular Disaggregase Hsp104 of Candida Albicans Plays a Role in Biofilm Formation and Pathogenicity in a Worm Infection Model
  Eukaryotic Cell. Aug, 2012  |   Pubmed ID: 22635920
• Potent Synergistic Effect of Doxycycline with Fluconazole Against Candida Albicans is Mediated by Interference with Iron Homeostasis
  Antimicrobial Agents and Chemotherapy. Jul, 2012  |   Pubmed ID: 22564841
• Transcription Factor Efg1 Contributes to the Tolerance of Candida Albicans Biofilms Against Antifungal Agents in Vitro and in Vivo
  Journal of Medical Microbiology. Jun, 2012  |   Pubmed ID: 22422573
• Heterozygous Missense Mutations in SMARCA2 Cause Nicolaides-Baraitser Syndrome
  Nature Genetics. Apr, 2012  |   Pubmed ID: 22366787
• Candida Biofilms and the Host: Models and New Concepts for Eradication
  International Journal of Microbiology. 2012  |   Pubmed ID: 22164167
• How Do Sugars Regulate Plant Growth?
  Frontiers in Plant Science. 2011  |   Pubmed ID: 22629265
• The Candida Albicans GAP Gene Family Encodes Permeases Involved in General and Specific Amino Acid Uptake and Sensing
  Eukaryotic Cell. Sep, 2011  |   Pubmed ID: 21764911
• Detailed Comparison of Candida Albicans and Candida Glabrata Biofilms Under Different Conditions and Their Susceptibility to Caspofungin and Anidulafungin
  Journal of Medical Microbiology. Sep, 2011  |   Pubmed ID: 21566087
• Stress Tolerance of the Saccharomyces Cerevisiae Adenylate Cyclase Fil1 (CYR1) Mutant Depends on Hsp26
  Journal of Molecular Microbiology and Biotechnology. 2010  |   Pubmed ID: 20924200
• Mutations in the SPTLC2 Subunit of Serine Palmitoyltransferase Cause Hereditary Sensory and Autonomic Neuropathy Type I
  American Journal of Human Genetics. Oct, 2010  |   Pubmed ID: 20920666
• A CUG Codon Adapted Two-hybrid System for the Pathogenic Fungus Candida Albicans
  Nucleic Acids Research. Oct, 2010  |   Pubmed ID: 20719741
• In Vivo Efficacy of Anidulafungin Against Mature Candida Albicans Biofilms in a Novel Rat Model of Catheter-associated Candidiasis
  Antimicrobial Agents and Chemotherapy. Oct, 2010  |   Pubmed ID: 20660685
• Candida Albicans Pde1p and Gpa2p Comprise a Regulatory Module Mediating Agonist-induced CAMP Signalling and Environmental Adaptation
  Fungal Genetics and Biology : FG & B. Sep, 2010  |   Pubmed ID: 20558315
• Real-time PCR Expression Profiling of Genes Encoding Potential Virulence Factors in Candida Albicans Biofilms: Identification of Model-dependent and -independent Gene Expression
  BMC Microbiology. 2010  |   Pubmed ID: 20398368
• A Single Active Trehalose-6-P Synthase (TPS) and a Family of Putative Regulatory TPS-like Proteins in Arabidopsis
  Molecular Plant. Mar, 2010  |   Pubmed ID: 20100798
• Candida Albicans Biofilm Formation in a New in Vivo Rat Model
  Microbiology (Reading, England). Mar, 2010  |   Pubmed ID: 19959578
• The Cytophaga Hutchinsonii ChTPSP: First Characterized Bifunctional TPS-TPP Protein As Putative Ancestor of All Eukaryotic Trehalose Biosynthesis Proteins
  Molecular Biology and Evolution. Feb, 2010  |   Pubmed ID: 19812028
• Nutrient Sensing G Protein-coupled Receptors: Interesting Targets for Antifungals?
  Medical Mycology. Nov, 2009  |   Pubmed ID: 19888799
• Small G Proteins in Peroxisome Biogenesis: the Potential Involvement of ADP-ribosylation Factor 6
  BMC Cell Biology. 2009  |   Pubmed ID: 19686593
• Dominant Mutations in the Tyrosyl-tRNA Synthetase Gene Recapitulate in Drosophila Features of Human Charcot-Marie-Tooth Neuropathy
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2009  |   Pubmed ID: 19561293
• Extensive Expression Regulation and Lack of Heterologous Enzymatic Activity of the Class II Trehalose Metabolism Proteins from Arabidopsis Thaliana
  Plant, Cell & Environment. Aug, 2009  |   Pubmed ID: 19344332
• Extracting Expression Modules from Perturbational Gene Expression Compendia
  BMC Systems Biology. 2008  |   Pubmed ID: 18402676
• Identification of Hexose Transporter-like Sensor HXS1 and Functional Hexose Transporter HXT1 in the Methylotrophic Yeast Hansenula Polymorpha
  Eukaryotic Cell. Apr, 2008  |   Pubmed ID: 18310355
• Flavour Formation in Fungi: Characterisation of KlAtf, the Kluyveromyces Lactis Orthologue of the Saccharomyces Cerevisiae Alcohol Acetyltransferases Atf1 and Atf2
  Applied Microbiology and Biotechnology. Apr, 2008  |   Pubmed ID: 18309479
• Combined Inactivation of the Candida Albicans GPR1 and TPS2 Genes Results in Avirulence in a Mouse Model for Systemic Infection
  Infection and Immunity. Apr, 2008  |   Pubmed ID: 18268028
• A Bifunctional TPS-TPP Enzyme from Yeast Confers Tolerance to Multiple and Extreme Abiotic-stress Conditions in Transgenic Arabidopsis
  Planta. Nov, 2007  |   Pubmed ID: 17628825
• Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida Albicans
  Microbiology and Molecular Biology Reviews : MMBR. Jun, 2007  |   Pubmed ID: 17554048
• Improved Drought Tolerance Without Undesired Side Effects in Transgenic Plants Producing Trehalose
  Plant Molecular Biology. Jul, 2007  |   Pubmed ID: 17453154
• Isolation and Characterization of Brewer's Yeast Variants with Improved Fermentation Performance Under High-gravity Conditions
  Applied and Environmental Microbiology. Feb, 2007  |   Pubmed ID: 17158628
• ABI4 Mediates the Effects of Exogenous Trehalose on Arabidopsis Growth and Starch Breakdown
  Plant Molecular Biology. Jan, 2007  |   Pubmed ID: 17031512
• Water Channels Are Important for Osmotic Adjustments of Yeast Cells at Low Temperature
  Microbiology (Reading, England). May, 2006  |   Pubmed ID: 16622068
• Disrupted Function and Axonal Distribution of Mutant Tyrosyl-tRNA Synthetase in Dominant Intermediate Charcot-Marie-Tooth Neuropathy
  Nature Genetics. Feb, 2006  |   Pubmed ID: 16429158
• Why Do Microorganisms Have Aquaporins?
  Trends in Microbiology. Feb, 2006  |   Pubmed ID: 16406529
• The Saccharomyces Cerevisiae EHT1 and EEB1 Genes Encode Novel Enzymes with Medium-chain Fatty Acid Ethyl Ester Synthesis and Hydrolysis Capacity
  The Journal of Biological Chemistry. Feb, 2006  |   Pubmed ID: 16361250
• Trehalose-6-phosphate Synthase As an Intrinsic Selection Marker for Plant Transformation
  Journal of Biotechnology. Feb, 2006  |   Pubmed ID: 16271790
• Heterologous Aquaporin (AQY2-1) Expression Strongly Enhances Freeze Tolerance of Schizosaccharomyces Pombe
  Journal of Molecular Microbiology and Biotechnology. 2005  |   Pubmed ID: 16254446
• Aquaporin Expression and Freeze Tolerance in Candida Albicans
  Applied and Environmental Microbiology. Oct, 2005  |   Pubmed ID: 16204575
• The G Protein-coupled Receptor Gpr1 and the Galpha Protein Gpa2 Act Through the CAMP-protein Kinase A Pathway to Induce Morphogenesis in Candida Albicans
  Molecular Biology of the Cell. Apr, 2005  |   Pubmed ID: 15673611
• The Arabidopsis Trehalose-6-P Synthase AtTPS1 Gene is a Regulator of Glucose, Abscisic Acid, and Stress Signaling
  Plant Physiology. Nov, 2004  |   Pubmed ID: 15516499
• Glucose and Sucrose Act As Agonist and Mannose As Antagonist Ligands of the G Protein-coupled Receptor Gpr1 in the Yeast Saccharomyces Cerevisiae
  Molecular Cell. Oct, 2004  |   Pubmed ID: 15494315
• Glucose and Sucrose: Hazardous Fast-food for Industrial Yeast?
  Trends in Biotechnology. Oct, 2004  |   Pubmed ID: 15450747
• New Selection Marker for Plant Transformation
  Methods in Molecular Biology (Clifton, N.J.). 2004  |   Pubmed ID: 15269438
• Aquaporin-mediated Improvement of Freeze Tolerance of Saccharomyces Cerevisiae is Restricted to Rapid Freezing Conditions
  Applied and Environmental Microbiology. Jun, 2004  |   Pubmed ID: 15184134
• The High General Stress Resistance of the Saccharomyces Cerevisiae Fil1 Adenylate Cyclase Mutant (Cyr1Lys1682) is Only Partially Dependent on Trehalose, Hsp104 and Overexpression of Msn2/4-regulated Genes
  Yeast (Chichester, England). Jan, 2004  |   Pubmed ID: 14745784
• Determinants of Freeze Tolerance in Microorganisms, Physiological Importance, and Biotechnological Applications
  Advances in Applied Microbiology. 2003  |   Pubmed ID: 14696318
• Multi-level Response of the Yeast Genome to Glucose
  Genome Biology. 2003  |   Pubmed ID: 14611650
• Progress in Functional Genomics Approaches to Antifungal Drug Target Discovery
  Trends in Microbiology. Oct, 2003  |   Pubmed ID: 14557030
• Uncoupling of the Glucose Growth Defect and the Deregulation of Glycolysis in Saccharomyces Cerevisiae Tps1 Mutants Expressing Trehalose-6-phosphate-insensitive Hexokinase from Schizosaccharomyces Pombe
  Biochimica Et Biophysica Acta. Sep, 2003  |   Pubmed ID: 14507429
• Activation State of Protein Kinase A As Measured in Permeabilised Saccharomyces Cerevisiae Cells Correlates with PKA-controlled Phenotypes in Vivo
  FEMS Yeast Research. Mar, 2003  |   Pubmed ID: 12702255
• Aquaporin Expression Correlates with Freeze Tolerance in Baker's Yeast, and Overexpression Improves Freeze Tolerance in Industrial Strains
  Applied and Environmental Microbiology. Dec, 2002  |   Pubmed ID: 12450819
• Isolation and Characterization of a Freeze-tolerant Diploid Derivative of an Industrial Baker's Yeast Strain and Its Use in Frozen Doughs
  Applied and Environmental Microbiology. Oct, 2002  |   Pubmed ID: 12324320
• Functional Genomics Approaches for the Identification and Validation of Antifungal Drug Targets
  American Journal of Pharmacogenomics : Genomics-related Research in Drug Development and Clinical Practice. 2002  |   Pubmed ID: 12083946
• Truncation of Arabidopsis Thaliana and Selaginella Lepidophylla Trehalose-6-phosphate Synthase Unlocks High Catalytic Activity and Supports High Trehalose Levels on Expression in Yeast
  The Biochemical Journal. Aug, 2002  |   Pubmed ID: 11978181
• Disruption of the Candida Albicans TPS2 Gene Encoding Trehalose-6-phosphate Phosphatase Decreases Infectivity Without Affecting Hypha Formation
  Infection and Immunity. Apr, 2002  |   Pubmed ID: 11895938