Paul N. Valdmanis Division of Medical Genetics University of Washington School of Medicine Biography Publications Institution JoVE Articles Paul N. ValdmanisPaul Valdmanis Paul Valdmanis, PhD is an Assistant Professor in the Division of Medical Genetics at the University of Washington School of Medicine. His lab works to uncover the genetic basis of neurodegenerative diseases and gene therapy techniques for therapeutic intervention. He has made important genetic discoveries including identifying mutations in the TAR-DNA binding protein (TARDBP) in patients with Amyotrophic Lateral Sclerosis. He has also worked extensively to establish methods to safely and efficiently reduce target genes through use of adeno-associated viral delivery of small hairpin RNAs and identified a mechanism by which small hairpin RNAs compete with endogenous microRNAs in the liver. Publications A Complete Pipeline for Isolating and Sequencing MicroRNAs, and Analyzing Them Using Open Source Tools Meredith M. Course1, Kathryn Gudsnuk1, Paul N. Valdmanis1 1Division of Medical Genetics, University of Washington School of Medicine JoVE 59901 Genetics
A Complete Pipeline for Isolating and Sequencing MicroRNAs, and Analyzing Them Using Open Source Tools Meredith M. Course1, Kathryn Gudsnuk1, Paul N. Valdmanis1 1Division of Medical Genetics, University of Washington School of Medicine JoVE 59901 Genetics