Paul W. Denton Department of Clinical Medicine Aarhus University Biography Publications Institution JoVE Articles Paul W. Denton has not added a biography. If you are Paul W. Denton and would like to personalize this page please email our Author Liaison for assistance. Publications Fimepinostat, a Novel Dual Inhibitor of HDAC and PI3K, Effectively Reverses HIV-1 Latency Without T Cell Activation Journal of Virus Eradication. Sep, 2019 | Pubmed ID: 31700656 Fimepinostat, a Novel Dual Inhibitor of HDAC and PI3K, Effectively Reverses HIV-1 Latency Without T Cell Activation Journal of Virus Eradication. Sep, 2019 | Pubmed ID: 31700655 Impacts of HIV Cure Interventions on Viral Reservoirs in Tissues Frontiers in Microbiology. 2019 | Pubmed ID: 31497010 TLR9 Agonist MGN1703 Enhances B Cell Differentiation and Function in Lymph Nodes EBioMedicine. Jul, 2019 | Pubmed ID: 31300344 Effects of 24-week Toll-like Receptor 9 Agonist Treatment in HIV Type 1+ Individuals AIDS (London, England). 07, 2019 | Pubmed ID: 30932955 CAIMP Administration in Humanized Mice Induces a Chimerization-level-dependent STING Response Immunology. 06, 2019 | Pubmed ID: 30919991 Characterization of Intact Proviruses in Blood and Lymph Node from HIV-Infected Individuals Undergoing Analytical Treatment Interruption Journal of Virology. 04, 2019 | Pubmed ID: 30700598 Non-covalent Hitchhiking on Endogenous Carriers As a Protraction Mechanism for Antiviral Macromolecular Prodrugs Journal of Controlled Release : Official Journal of the Controlled Release Society. 01, 2019 | Pubmed ID: 30552954 Genetic Characterization of the HIV-1 Reservoir After Vacc-4x and Romidepsin Therapy in HIV-1-infected Individuals AIDS (London, England). 08, 2018 | Pubmed ID: 29762162 Treatment of HIV-Infected Individuals with the Histone Deacetylase Inhibitor Panobinostat Results in Increased Numbers of Regulatory T Cells and Limits Lipopolysaccharide-Induced Inflammatory Responses MSphere. Jan-Feb, 2018 | Pubmed ID: 29468194 Acute Appendicitis As the Initial Clinical Presentation of Primary HIV-1 Infection Open Forum Infectious Diseases. Feb, 2018 | Pubmed ID: 29423422 The TLR9 Agonist MGN1703 Triggers a Potent Type I Interferon Response in the Sigmoid Colon Mucosal Immunology. Mar, 2018 | Pubmed ID: 28766555 The Role of MiR-29a in HIV-1 Replication and Latency Journal of Virus Eradication. Oct, 2017 | Pubmed ID: 29057080 Predictive Value of Galectin-1 in the Development and Progression of HIV-associated Lymphoma AIDS (London, England). 10, 2017 | Pubmed ID: 28991028 Short-Course Toll-Like Receptor 9 Agonist Treatment Impacts Innate Immunity and Plasma Viremia in Individuals With Human Immunodeficiency Virus Infection Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Jun, 2017 | Pubmed ID: 28329286 Combined Effect of Vacc-4x, Recombinant Human Granulocyte Macrophage Colony-stimulating Factor Vaccination, and Romidepsin on the HIV-1 Reservoir (REDUC): a Single-arm, Phase 1B/2A Trial The Lancet. HIV. 10, 2016 | Pubmed ID: 27658863 Broad Activation of Latent HIV-1 in Vivo Nature Communications. 09, 2016 | Pubmed ID: 27605062 Immune Checkpoints and the HIV-1 Reservoir: Proceed with Caution Journal of Virus Eradication. Jul, 2016 | Pubmed ID: 27482460 A Novel Toll-Like Receptor 9 Agonist, MGN1703, Enhances HIV-1 Transcription and NK Cell-Mediated Inhibition of HIV-1-Infected Autologous CD4+ T Cells Journal of Virology. May, 2016 | Pubmed ID: 26889036 Using Animal Models to Overcome Temporal, Spatial and Combinatorial Challenges in HIV Persistence Research Journal of Translational Medicine. Feb, 2016 | Pubmed ID: 26861779 ART Influences HIV Persistence in the Female Reproductive Tract and Cervicovaginal Secretions The Journal of Clinical Investigation. Mar, 2016 | Pubmed ID: 26854925 HIV-1 Transcriptional Activity During Frequent Longitudinal Sampling in Aviremic Patients on Antiretroviral Therapy AIDS (London, England). Mar, 2016 | Pubmed ID: 26595541 Administration of Panobinostat Is Associated with Increased IL-17A MRNA in the Intestinal Epithelium of HIV-1 Patients Mediators of Inflammation. 2015 | Pubmed ID: 26696749 The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo PLoS Pathogens. Sep, 2015 | Pubmed ID: 26379282 Histone Deacetylase Inhibitor Romidepsin Inhibits De Novo HIV-1 Infections Antimicrobial Agents and Chemotherapy. Jul, 2015 | Pubmed ID: 25896701 Human Breast Milk and Antiretrovirals Dramatically Reduce Oral HIV-1 Transmission in BLT Humanized Mice PLoS Pathogens. 2012 | Pubmed ID: 22737068 Generation of HIV Latency in Humanized BLT Mice Journal of Virology. Jan, 2012 | Pubmed ID: 22013053 Immune Reconstitution of the Female Reproductive Tract of Humanized BLT Mice and Their Susceptibility to Human Immunodeficiency Virus Infection Journal of Reproductive Immunology. Mar, 2011 | Pubmed ID: 21256601 질 내 HIV 노출 및 HIV 감염 치료를 위한 인간화된 NOG 마우스 Anna H. F. Andersen1,2, Stine S. F. Nielsen1,2, Rikke Olesen1,2, Katharina Mack1, Frederik Dagnæs-Hansen3, Niels Uldbjerg1,4, Lars Østergaard1,2, Ole S. Søgaard1,2, Paul W. Denton1,2,5, Martin Tolstrup1,2 1Department of Clinical Medicine, Aarhus University, 2Department of Infectious Diseases, Aarhus University Hospital, 3Department of Biomedicine, Aarhus University, 4Department of Gynecology and Obstetrics, Aarhus University Hospital, 5Department of Biology, University of Nebraska at Omaha JoVE 60723 Immunology and Infection
질 내 HIV 노출 및 HIV 감염 치료를 위한 인간화된 NOG 마우스 Anna H. F. Andersen1,2, Stine S. F. Nielsen1,2, Rikke Olesen1,2, Katharina Mack1, Frederik Dagnæs-Hansen3, Niels Uldbjerg1,4, Lars Østergaard1,2, Ole S. Søgaard1,2, Paul W. Denton1,2,5, Martin Tolstrup1,2 1Department of Clinical Medicine, Aarhus University, 2Department of Infectious Diseases, Aarhus University Hospital, 3Department of Biomedicine, Aarhus University, 4Department of Gynecology and Obstetrics, Aarhus University Hospital, 5Department of Biology, University of Nebraska at Omaha JoVE 60723 Immunology and Infection
