Publications

• Single-molecule Fluorescence and in Vivo Optical Traps: How Multiple Dyneins and Kinesins Interact
  Chemical Reviews. Mar, 2014  |   Pubmed ID: 24666199
• Single Molecule FRET Reveals Pore Size and Opening Mechanism of a Mechano-sensitive Ion Channel
  ELife. 2014  |   Pubmed ID: 24550255
• 3D Super-Resolution Imaging with Blinking Quantum Dots
  Nano Letters. Nov, 2013  |   Pubmed ID: 24093439
• Motor Domain Phosphorylation Modulates Kinesin-1 Transport
  The Journal of Biological Chemistry. Nov, 2013  |   Pubmed ID: 24072715
• In Vivo Optical Trapping Indicates Kinesin's Stall Force is Reduced by Dynein During Intracellular Transport
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2013  |   Pubmed ID: 23404705
• Direct Detection of Adenosine in Undiluted Serum Using a Luminescent Aptamer Sensor Attached to a Terbium Complex
  Analytical Chemistry. Sep, 2012  |   Pubmed ID: 22894546
• Using Fixed Fiduciary Markers for Stage Drift Correction
  Optics Express. May, 2012  |   Pubmed ID: 22714205
• Multicolor Super-resolution DNA Imaging for Genetic Analysis
  Nano Letters. Jul, 2012  |   Pubmed ID: 22698062
• Biomimetic Surface Engineering of Lanthanide-doped Upconversion Nanoparticles As Versatile Bioprobes
  Angewandte Chemie (International Ed. in English). Jun, 2012  |   Pubmed ID: 22566291
• Single-molecule-based Super-resolution Images in the Presence of Multiple Fluorophores
  Nano Letters. Nov, 2011  |   Pubmed ID: 22003850
• Two-photon 3D FIONA of Individual Quantum Dots in an Aqueous Environment
  Nano Letters. Oct, 2011  |   Pubmed ID: 21882883
• Fluorescence Imaging with One Nanometer Accuracy: in Vitro and in Vivo Studies of Molecular Motors
  Methods in Molecular Biology (Clifton, N.J.). 2011  |   Pubmed ID: 21809199
• Extension of a Three-helix Bundle Domain of Myosin VI and Key Role of Calmodulins
  Biophysical Journal. Jun, 2011  |   Pubmed ID: 21689530
• Single-virus Tracking Reveals a Spatial Receptor-dependent Search Mechanism
  Biophysical Journal. Jun, 2011  |   Pubmed ID: 21689520
• Improved Hidden Markov Models for Molecular Motors, Part 2: Extensions and Application to Experimental Data
  Biophysical Journal. Dec, 2010  |   Pubmed ID: 21112294
• Improved Hidden Markov Models for Molecular Motors, Part 1: Basic Theory
  Biophysical Journal. Dec, 2010  |   Pubmed ID: 21112293
• Counting Bungarotoxin Binding Sites of Nicotinic Acetylcholine Receptors in Mammalian Cells with High Signal/noise Ratios
  Biophysical Journal. Nov, 2010  |   Pubmed ID: 21081055
• Formation of Salt Bridges Mediates Internal Dimerization of Myosin VI Medial Tail Domain
  Structure (London, England : 1993). Nov, 2010  |   Pubmed ID: 21070943
• Super-accuracy and Super-resolution Getting Around the Diffraction Limit
  Methods in Enzymology. 2010  |   Pubmed ID: 20627151
• Myosin VI Undergoes a 180 Degrees Power Stroke Implying an Uncoupling of the Front Lever Arm
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2009  |   Pubmed ID: 19828438
• Myosin VI Dimerization Triggers an Unfolding of a Three-helix Bundle in Order to Extend Its Reach
  Molecular Cell. Aug, 2009  |   Pubmed ID: 19664948
• Why Kinesin is So Processive
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2009  |   Pubmed ID: 19617538
• FIONA on Caenorhabditis Elegans
  Biochemistry. Jun, 2009  |   Pubmed ID: 19397310
• The Role of Microtubule Movement in Bidirectional Organelle Transport
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2008  |   Pubmed ID: 18626022
• Extent of Voltage Sensor Movement During Gating of Shaker K+ Channels
  Neuron. Jul, 2008  |   Pubmed ID: 18614032
• New 9- or 10-dentate Luminescent Lanthanide Chelates
  Bioconjugate Chemistry. May, 2008  |   Pubmed ID: 18442281
• The Mitotic Kinesin CENP-E is a Processive Transport Motor
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2008  |   Pubmed ID: 18427114
• Fluorescence Imaging with One-Nanometer Accuracy (FIONA)
  CSH Protocols. 2007  |   Pubmed ID: 21356960
• Fluorescence Imaging with One-Nanometer Accuracy (FIONA) of Cy3-DNA Under Deoxygenation Conditions
  CSH Protocols. 2007  |   Pubmed ID: 21356956
• Constructing Sample Chambers for Fluorescence Imaging with One-Nanometer Accuracy (FIONA)
  CSH Protocols. 2007  |   Pubmed ID: 21356955
• Data Analysis Methods for Fluorescence Imaging with One-Nanometer Accuracy (FIONA)
  CSH Protocols. 2007  |   Pubmed ID: 21356943
• Equipment Setup for Fluorescence Imaging with One-Nanometer Accuracy (FIONA)
  CSH Protocols. 2007  |   Pubmed ID: 21356942
• Single-molecule Fluorescence to Study Molecular Motors
  Quarterly Reviews of Biophysics. Feb, 2007  |   Pubmed ID: 17666122
• Three-dimensional Particle Tracking Via Bifocal Imaging
  Nano Letters. Jul, 2007  |   Pubmed ID: 17583964
• How Myosin VI Coordinates Its Heads During Processive Movement
  The EMBO Journal. Jun, 2007  |   Pubmed ID: 17510632
• Determination of Haplotypes from Single DNA Molecules: a Method for Single-molecule Barcoding
  Human Mutation. Sep, 2007  |   Pubmed ID: 17443670
• Tracking Melanosomes Inside a Cell to Study Molecular Motors and Their Interaction
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2007  |   Pubmed ID: 17369356
• Microtubule Binding by Dynactin is Required for Microtubule Organization but Not Cargo Transport
  The Journal of Cell Biology. Feb, 2007  |   Pubmed ID: 17325206
• New Fluorescent Tools for Watching Nanometer-scale Conformational Changes of Single Molecules
  Annual Review of Biophysics and Biomolecular Structure. 2007  |   Pubmed ID: 17298239
• The Unique Insert at the End of the Myosin VI Motor is the Sole Determinant of Directionality
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2007  |   Pubmed ID: 17213313
• Rapid DNA Mapping by Fluorescent Single Molecule Detection
  Nucleic Acids Research. 2007  |   Pubmed ID: 17175538
• Polarization Effect on Position Accuracy of Fluorophore Localization
  Optics Express. Sep, 2006  |   Pubmed ID: 19529183
• Distance Measurements Reveal a Common Topology of Prokaryotic Voltage-gated Ion Channels in the Lipid Bilayer
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2006  |   Pubmed ID: 17043236
• Extracting Dwell Time Sequences from Processive Molecular Motor Data
  Biophysical Journal. Nov, 2006  |   Pubmed ID: 16905607
• Maximum Likelihood Estimation of Molecular Motor Kinetics from Staircase Dwell-time Sequences
  Biophysical Journal. Aug, 2006  |   Pubmed ID: 16679362
• Defocused Orientation and Position Imaging (DOPI) of Myosin V
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2006  |   Pubmed ID: 16614073
• Adaptability of Myosin V Studied by Simultaneous Detection of Position and Orientation
  The EMBO Journal. May, 2006  |   Pubmed ID: 16601691
• Full-length Myosin VI Dimerizes and Moves Processively Along Actin Filaments Upon Monomer Clustering
  Molecular Cell. Feb, 2006  |   Pubmed ID: 16455488
• Molecular Motors One at a Time: FIONA to the Rescue
  Journal of Physics. Condensed Matter : an Institute of Physics Journal. Nov, 2005  |   Pubmed ID: 21690736
• Step-size is Determined by Neck Length in Myosin V
  Biochemistry. Dec, 2005  |   Pubmed ID: 16331980
• Small Vertical Movement of a K+ Channel Voltage Sensor Measured with Luminescence Energy Transfer
  Nature. Aug, 2005  |   Pubmed ID: 16094368
• Fluorescence Imaging with One Nanometer Accuracy: Application to Molecular Motors
  Accounts of Chemical Research. Jul, 2005  |   Pubmed ID: 16028892
• Interhead Distance Measurements in Myosin VI Via SHRImP Support a Simplified Hand-over-hand Model
  Biophysical Journal. Jul, 2005  |   Pubmed ID: 15863481
• Kinesin and Dynein Move a Peroxisome in Vivo: a Tug-of-war or Coordinated Movement?
  Science (New York, N.Y.). Jun, 2005  |   Pubmed ID: 15817813
• Kinesin: Walking, Crawling or Sliding Along?
  Trends in Cell Biology. Feb, 2005  |   Pubmed ID: 15695098
• Carbostyril Derivatives As Antenna Molecules for Luminescent Lanthanide Chelates
  Bioconjugate Chemistry. Sep-Oct, 2004  |   Pubmed ID: 15366964
• Nanometer Localization of Single Green Fluorescent Proteins: Evidence That Myosin V Walks Hand-over-hand Via Telemark Configuration
  Biophysical Journal. Sep, 2004  |   Pubmed ID: 15345556
• Myosin VI Steps Via a Hand-over-hand Mechanism with Its Lever Arm Undergoing Fluctuations when Attached to Actin
  The Journal of Biological Chemistry. Sep, 2004  |   Pubmed ID: 15254036
• Single-molecule High-resolution Imaging with Photobleaching
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2004  |   Pubmed ID: 15096603
• Kinesin Walks Hand-over-hand
  Science (New York, N.Y.). Jan, 2004  |   Pubmed ID: 14684828
• Does the S2 Rod of Myosin II Uncoil Upon Two-headed Binding to Actin? A Leucine-zippered HMM Study
  Biochemistry. Nov, 2003  |   Pubmed ID: 14596602
• Thiol-reactive Luminescent Lanthanide Chelates: Part 2
  Bioconjugate Chemistry. Sep-Oct, 2003  |   Pubmed ID: 13129389
• Myosin V Walks Hand-over-hand: Single Fluorophore Imaging with 1.5-nm Localization
  Science (New York, N.Y.). Jun, 2003  |   Pubmed ID: 12791999
• An Actin-dependent Conformational Change in Myosin
  Nature Structural Biology. May, 2003  |   Pubmed ID: 12679807
• Lighting Up Single Ion Channels
  Biophysical Journal. Jan, 2003  |   Pubmed ID: 12524260
• Thiol-reactive Lanthanide Chelates for Phasing Protein X-ray Diffraction Data
  Acta Crystallographica. Section D, Biological Crystallography. Jul, 2002  |   Pubmed ID: 12077430
• Principles and Biophysical Applications of Lanthanide-based Probes
  Annual Review of Biophysics and Biomolecular Structure. 2002  |   Pubmed ID: 11988471
• Holding Two Heads Together: Stability of the Myosin II Rod Measured by Resonance Energy Transfer Between the Heads
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2002  |   Pubmed ID: 11972024