Peter Macheroux Institute of Biochemistry Graz University of Technology Biography Publications Institution JoVE Articles Peter Macheroux has not added a biography. If you are Peter Macheroux and would like to personalize this page please email our Author Liaison for assistance. Publications Asymmetric Reductive Carbocyclization Using Engineered Ene Reductases Angewandte Chemie (International Ed. in English). Jun, 2018 | Pubmed ID: 29689601 The Single Berberine Bridge Enzyme Homolog of Physcomitrella patens is a Cellobiose Oxidase The FEBS Journal. May, 2018 | Pubmed ID: 29633551 Oxidation of the FAD Cofactor to the 8-formyl-derivative in Human Electron-transferring Flavoprotein The Journal of Biological Chemistry. Feb, 2018 | Pubmed ID: 29301933 Crystal Structure of Dipeptidyl Peptidase III from the Human Gut Symbiont Bacteroides Thetaiotaomicron PloS One. 2017 | Pubmed ID: 29095893 Regioselective Para-Carboxylation of Catechols with a Prenylated Flavin Dependent Decarboxylase Angewandte Chemie (International Ed. in English). Oct, 2017 | Pubmed ID: 28857436 Biosensor for the Characterisation of HMAO B Inhibitors and the Quantification of Selegiline Talanta. Nov, 2017 | Pubmed ID: 28738644 The Family of Berberine Bridge Enzyme-like Enzymes: A Treasure-trove of Oxidative Reactions Archives of Biochemistry and Biophysics. 10, 2017 | Pubmed ID: 28676375 Structure, Biochemical and Kinetic Properties of Recombinant Pst2p from Saccharomyces Cerevisiae, a FMN-dependent NAD(P)H:quinone Oxidoreductase Biochimica Et Biophysica Acta. 08, 2017 | Pubmed ID: 28499769 Evidence for the Generation of Myristylated FMN by Bacterial Luciferase Molecular Microbiology. Jun, 2017 | Pubmed ID: 28345146 Catalytic Competence, Structure and Stability of the Cancer-associated R139W Variant of the Human NAD(P)H:quinone Oxidoreductase 1 (NQO1) The FEBS Journal. 04, 2017 | Pubmed ID: 28236663 Synthesis of α,β-unsaturated Aldehydes As Potential Substrates for Bacterial Luciferases Bioorganic & Medicinal Chemistry. 02, 2017 | Pubmed ID: 28126438 Leucine 208 in Human Histamine N-methyltransferase Emerges As a Hotspot for Protein Stability Rationalizing the Role of the L208P Variant in Intellectual Disability Biochimica Et Biophysica Acta. Jan, 2017 | Pubmed ID: 27769936 Structure and Biochemical Properties of Recombinant Human Dimethylglycine Dehydrogenase and Comparison to the Disease-related H109R Variant The FEBS Journal. 10, 2016 | Pubmed ID: 27486859 Structure of a Berberine Bridge Enzyme-Like Enzyme with an Active Site Specific to the Plant Family Brassicaceae PloS One. 2016 | Pubmed ID: 27276217 Substrate Complexes of Human Dipeptidyl Peptidase III Reveal the Mechanism of Enzyme Inhibition Scientific Reports. Mar, 2016 | Pubmed ID: 27025154 Structural and Kinetic Studies on RosA, the Enzyme Catalysing the Methylation of 8-demethyl-8-amino-d-riboflavin to the Antibiotic Roseoflavin The FEBS Journal. Apr, 2016 | Pubmed ID: 26913589 Structural and Biochemical Properties of LuxF from Photobacterium Leiognathi Biochimica Et Biophysica Acta. Oct, 2015 | Pubmed ID: 26209460 Mutations in the Histamine N-methyltransferase Gene, HNMT, Are Associated with Nonsyndromic Autosomal Recessive Intellectual Disability Human Molecular Genetics. Oct, 2015 | Pubmed ID: 26206890 Structure-Based Mechanism of Oleate Hydratase from Elizabethkingia Meningoseptica Chembiochem : a European Journal of Chemical Biology. Aug, 2015 | Pubmed ID: 26077980 Oxidation of Monolignols by Members of the Berberine Bridge Enzyme Family Suggests a Role in Plant Cell Wall Metabolism The Journal of Biological Chemistry. Jul, 2015 | Pubmed ID: 26037923 Anthranoyl-CoA Monooxygenase/reductase from Azoarcus Evansii Possesses Both FMN and FAD in Two Distinct and Independent Active Sites Biochimica Et Biophysica Acta. Aug, 2015 | Pubmed ID: 25843773 Rationally Engineered Flavin-dependent Oxidase Reveals Steric Control of Dioxygen Reduction The FEBS Journal. Aug, 2015 | Pubmed ID: 25619330 Structure and Stability of an Unusual Zinc-binding Protein from Bacteroides Thetaiotaomicron Biochimica Et Biophysica Acta. Dec, 2014 | Pubmed ID: 25263158 Collapse of the Native Structure Caused by a Single Amino Acid Exchange in Human NAD(P)H:quinone Oxidoreductase(1.) The FEBS Journal. Oct, 2014 | Pubmed ID: 25143260 Identification of Promiscuous Ene-reductase Activity by Mining Structural Databases Using Active Site Constellations Nature Communications. Jun, 2014 | Pubmed ID: 24954722 Disruption of the Methyltransferase-like 23 Gene METTL23 Causes Mild Autosomal Recessive Intellectual Disability Human Molecular Genetics. Aug, 2014 | Pubmed ID: 24626631 The Flavoproteome of the Yeast Saccharomyces Cerevisiae Biochimica Et Biophysica Acta. Mar, 2014 | Pubmed ID: 24373875 Determination of Free and Bound Riboflavin in Cow's Milk Using a Novel Flavin-binding Protein Food Chemistry. Mar, 2014 | Pubmed ID: 24176318 One-Pot Deracemization of Sec-Alcohols: Enantioconvergent Enzymatic Hydrolysis of Alkyl Sulfates Using Stereocomplementary Sulfatases Angewandte Chemie (Weinheim an Der Bergstrasse, Germany). Mar, 2013 | Pubmed ID: 25821253 The Human Flavoproteome Archives of Biochemistry and Biophysics. Jul, 2013 | Pubmed ID: 23500531 One-pot Deracemization of Sec-alcohols: Enantioconvergent Enzymatic Hydrolysis of Alkyl Sulfates Using Stereocomplementary Sulfatases Angewandte Chemie (International Ed. in English). Mar, 2013 | Pubmed ID: 23401148 Structure and Mechanism of an Inverting Alkylsulfatase from Pseudomonas Sp. DSM6611 Specific for Secondary Alkyl Sulfates The FEBS Journal. Dec, 2012 | Pubmed ID: 23061549 Structural and Functional Characterization of NikO, an Enolpyruvyl Transferase Essential in Nikkomycin Biosynthesis The Journal of Biological Chemistry. Sep, 2012 | Pubmed ID: 22810238 Catalytic and Structural Role of a Conserved Active Site Histidine in Berberine Bridge Enzyme Biochemistry. Aug, 2012 | Pubmed ID: 22757961 Reverse Structural Genomics: an Unusual Flavin-binding Site in a Putative Protease from Bacteroides Thetaiotaomicron The Journal of Biological Chemistry. Aug, 2012 | Pubmed ID: 22718753 Activity-based Probes for Studying the Activity of Flavin-dependent Oxidases and for the Protein Target Profiling of Monoamine Oxidase Inhibitors Angewandte Chemie (International Ed. in English). Jul, 2012 | Pubmed ID: 22689512 Entropy-driven Binding of Opioid Peptides Induces a Large Domain Motion in Human Dipeptidyl Peptidase III Proceedings of the National Academy of Sciences of the United States of America. Apr, 2012 | Pubmed ID: 22493238 A Novel N,N-8-amino-8-demethyl-D-riboflavin Dimethyltransferase (RosA) Catalyzing the Two Terminal Steps of Roseoflavin Biosynthesis in Streptomyces Davawensis The Journal of Biological Chemistry. Nov, 2011 | Pubmed ID: 21911488 Characterization of the PLP-dependent Aminotransferase NikK from Streptomyces Tendae and Its Putative Role in Nikkomycin Biosynthesis The FEBS Journal. Nov, 2011 | Pubmed ID: 21884568 A Stereoselective Inverting Sec-alkylsulfatase for the Deracemization of Sec-alcohols Organic Letters. Aug, 2011 | Pubmed ID: 21770430 Biocatalytic Organic Synthesis of Optically Pure (S)-scoulerine and Berbine and Benzylisoquinoline Alkaloids The Journal of Organic Chemistry. Aug, 2011 | Pubmed ID: 21739961 Flavogenomics--a Genomic and Structural View of Flavin-dependent Proteins The FEBS Journal. Aug, 2011 | Pubmed ID: 21635694 The Redox-sensing Quinone Reductase Lot6p Acts As an Inducer of Yeast Apoptosis FEMS Yeast Research. Sep, 2009 | Pubmed ID: 19709309 A Single Intersubunit Salt Bridge Affects Oligomerization and Catalytic Activity in a Bacterial Quinone Reductase The FEBS Journal. Sep, 2009 | Pubmed ID: 19682074 Mechanism of Flavin Reduction and Oxidation in the Redox-sensing Quinone Reductase Lot6p from Saccharomyces Cerevisiae Biochemistry. Sep, 2009 | Pubmed ID: 19618916 Berberine Bridge Enzyme Catalyzes the Six Electron Oxidation of (S)-reticuline to Dehydroscoulerine Phytochemistry. Jun, 2009 | Pubmed ID: 19570558 Structural and Mechanistic Studies Reveal the Functional Role of Bicovalent Flavinylation in Berberine Bridge Enzyme The Journal of Biological Chemistry. Jul, 2009 | Pubmed ID: 19457868 Quinone Reductase Acts As a Redox Switch of the 20S Yeast Proteasome EMBO Reports. Jan, 2009 | Pubmed ID: 19029946 A Concerted Mechanism for Berberine Bridge Enzyme Nature Chemical Biology. Dec, 2008 | Pubmed ID: 18953357 Replacement of Two Invariant Serine Residues in Chorismate Synthase Provides Evidence That a Proton Relay System is Essential for Intermediate Formation and Catalytic Activity The FEBS Journal. Apr, 2008 | Pubmed ID: 18279385 Conservation of NADPH Utilization by Chorismate Synthase and Its Implications for the Evolution of the Shikimate Pathway Molecular Microbiology. Sep, 2007 | Pubmed ID: 17662045 6-S-cysteinylation of Bi-covalently Attached FAD in Berberine Bridge Enzyme Tunes the Redox Potential for Optimal Activity The Journal of Biological Chemistry. Aug, 2007 | Pubmed ID: 17573342 Mutagenic Analysis of an Invariant Aspartate Residue in Chorismate Synthase Supports Its Role As an Active Site Base Biochemistry. Mar, 2007 | Pubmed ID: 17326665 Lot6p from Saccharomyces Cerevisiae is a FMN-dependent Reductase with a Potential Role in Quinone Detoxification The FEBS Journal. Mar, 2007 | Pubmed ID: 17298444 Crystal Structure of 12-oxophytodienoate Reductase 3 from Tomato: Self-inhibition by Dimerization Proceedings of the National Academy of Sciences of the United States of America. Sep, 2006 | Pubmed ID: 16983071 Characterization of a Thermostable NADPH:FMN Oxidoreductase from the Mesophilic Bacterium Bacillus Subtilis Biochemistry. Jun, 2006 | Pubmed ID: 16752898 Biochemical Evidence That Berberine Bridge Enzyme Belongs to a Novel Family of Flavoproteins Containing a Bi-covalently Attached FAD Cofactor The Journal of Biological Chemistry. Jul, 2006 | Pubmed ID: 16728404 Reduced Flavin: NMR Investigation of N5-H Exchange Mechanism, Estimation of Ionisation Constants and Assessment of Properties As Biological Catalyst BMC Biochemistry. Nov, 2005 | Pubmed ID: 16309555 Situ Ölçüm ve korelasyon hücre yoğunluğu ve kollarındaki bakterilerin ışık emisyon Eveline Brodl1, Johannes Niederhauser1, Peter Macheroux1 1Institute of Biochemistry, Graz University of Technology JoVE 57881 Biochemistry
Situ Ölçüm ve korelasyon hücre yoğunluğu ve kollarındaki bakterilerin ışık emisyon Eveline Brodl1, Johannes Niederhauser1, Peter Macheroux1 1Institute of Biochemistry, Graz University of Technology JoVE 57881 Biochemistry