Petra Knaus

Publications

• Optimized Expression and Purification of a Soluble BMP2 Variant Based on In-silico Design
  Protein Expression and Purification. Oct, 2021  |   Pubmed ID: 34044133
• ActivinA Induced SMAD1/5 Signaling in an IPSC Derived EC Model of Fibrodysplasia Ossificans Progressiva (FOP) Can Be Rescued by the Drug Candidate Saracatinib
  Stem Cell Reviews and Reports. Jun, 2021  |   Pubmed ID: 33410098
• Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling During Zebrafish Cardiac Valvulogenesis
  Cell Reports. 07, 2020  |   Pubmed ID: 32668254
• BMP Signalling in a Mechanical Context - Implications for Bone Biology
  Bone. 08, 2020  |   Pubmed ID: 32422297
• Biomechanical Stress Provides a Second Hit in the Establishment of BMP/TGFβ-related Vascular Disorders
  Cell Stress. Jan, 2020  |   Pubmed ID: 32043077
• AMOT130 Drives BMP-SMAD Signaling at the Apical Membrane in Polarized Cells
  Molecular Biology of the Cell. 01, 2020  |   Pubmed ID: 31800378
• BMPR2 Acts As A gatekeeper to Protect Endothelial Cells from Increased TGFβ responses and Altered Cell Mechanics
  PLoS Biology. 12, 2019  |   Pubmed ID: 31826007
• Sex-specific Metabolic and Functional Differences in Human Umbilical Vein Endothelial Cells from Twin Pairs
  Atherosclerosis. 12, 2019  |   Pubmed ID: 31706078
• Lessons from LIMK1 Enzymology and Their Impact on Inhibitor Design
  The Biochemical Journal. 11, 2019  |   Pubmed ID: 31652302
• Is NO the Answer? The Nitric Oxide Pathway Can Support Bone Morphogenetic Protein 2 Mediated Signaling
  Cells. 10, 2019  |   Pubmed ID: 31635347
• Load-induced Osteogenic Differentiation of Mesenchymal Stromal Cells is Caused by Mechano-regulated Autocrine Signaling
  Journal of Tissue Engineering and Regenerative Medicine. 11, 2019  |   Pubmed ID: 31359634
• Cofilin-1 Phosphorylation Catalyzed by ERK1/2 Alters Cardiac Actin Dynamics in Dilated Cardiomyopathy Caused by Lamin A/C Gene Mutation
  Human Molecular Genetics. 09, 2018  |   Pubmed ID: 29878125
• Impaired Proteoglycan Glycosylation, Elevated TGF-β Signaling, and Abnormal Osteoblast Differentiation As the Basis for Bone Fragility in a Mouse Model for Gerodermia Osteodysplastica
  PLoS Genetics. 03, 2018  |   Pubmed ID: 29561836
• Cell-specific Responses to the Cytokine TGFβ Are Determined by Variability in Protein Levels
  Molecular Systems Biology. 01, 2018  |   Pubmed ID: 29371237
• Enhanced Biological Activity of BMP-2 Bound to Surface-Grafted Heparan Sulfate
  Advanced Biosystems. Apr, 2017  |   Pubmed ID: 32646162
• Correction for Bagarova Et Al., "Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation"
  Molecular and Cellular Biology. 10, 2017  |   Pubmed ID: 28899999
• IRS4, a Novel Modulator of BMP/Smad and Akt Signalling During Early Muscle Differentiation
  Scientific Reports. 08, 2017  |   Pubmed ID: 28821740
• Role of Bone Morphogenetic Proteins in Sprouting Angiogenesis: Differential BMP Receptor-dependent Signaling Pathways Balance Stalk Tip Cell Competence
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 11, 2017  |   Pubmed ID: 28733457
• The Role of Titanium Surface Nanostructuring on Preosteoblast Morphology, Adhesion, and Migration
  Advanced Healthcare Materials. Aug, 2017  |   Pubmed ID: 28371540
• Dynamin-dependent Endocytosis of Bone Morphogenetic Protein2 (BMP2) and Its Receptors is Dispensable for the Initiation of Smad Signaling
  The International Journal of Biochemistry & Cell Biology. 07, 2016  |   Pubmed ID: 27113717
• YAP-Mediated Mechanotransduction in Skeletal Muscle
  Frontiers in Physiology. 2016  |   Pubmed ID: 26909043
• Emerging Regulators of BMP Bioavailability
  Bone. Dec, 2016  |   Pubmed ID: 26825814
• Actions from Head to Toe: An Update on Bone/Body Morphogenetic Proteins in Health and Disease
  Cytokine & Growth Factor Reviews. Feb, 2016  |   Pubmed ID: 26803465
• VE-cadherin Facilitates BMP-induced Endothelial Cell Permeability and Signaling
  Journal of Cell Science. Jan, 2016  |   Pubmed ID: 26598555
• Bone Morphogenetic Protein Signaling in Bone Homeostasis
  Bone. Nov, 2015  |   Pubmed ID: 26051467
• Small Molecules Dorsomorphin and LDN-193189 Inhibit Myostatin/GDF8 Signaling and Promote Functional Myoblast Differentiation
  The Journal of Biological Chemistry. Feb, 2015  |   Pubmed ID: 25368322
• BMP10 As a Potent Inducer of Trophoblast Differentiation in Human Embryonic and Induced Pluripotent Stem Cells
  Biomaterials. Dec, 2013  |   Pubmed ID: 24070570
• Growth and Differentiation Factor 3 Induces Expression of Genes Related to Differentiation in a Model of Cancer Stem Cells and Protects Them from Retinoic Acid-induced Apoptosis
  PloS One. 2013  |   Pubmed ID: 23950971
• Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation
  Molecular and Cellular Biology. Jun, 2013  |   Pubmed ID: 23572558
• Structure of the Bone Morphogenetic Protein Receptor ALK2 and Implications for Fibrodysplasia Ossificans Progressiva
  The Journal of Biological Chemistry. Oct, 2012  |   Pubmed ID: 22977237
• SMAD Versus Non-SMAD Signaling is Determined by Lateral Mobility of Bone Morphogenetic Protein (BMP) Receptors
  The Journal of Biological Chemistry. Nov, 2012  |   Pubmed ID: 22961979
• BMPs Are Mediators in Tissue Crosstalk of the Regenerating Musculoskeletal System
  Cell and Tissue Research. Mar, 2012  |   Pubmed ID: 22327483
• A Portrait of Transforming Growth Factor β Superfamily Signalling: Background Matters
  The International Journal of Biochemistry & Cell Biology. Mar, 2012  |   Pubmed ID: 22226817
• Comprehensive Analysis of TGF-β and BMP Receptor Interactomes
  European Journal of Cell Biology. Apr, 2012  |   Pubmed ID: 21715044
• MicroRNAs Differentially Expressed in Postnatal Aortic Development Downregulate Elastin Via 3' UTR and Coding-sequence Binding Sites
  PloS One. Jan, 2011  |   Pubmed ID: 21305018
• Noggin
  The International Journal of Biochemistry & Cell Biology. Apr, 2011  |   Pubmed ID: 21256973
• Quantitative Analysis of TGFBR2 Mutations in Marfan-syndrome-related Disorders Suggests a Correlation Between Phenotypic Severity and Smad Signaling Activity
  Journal of Cell Science. Dec, 2010  |   Pubmed ID: 21098638
• Recent Advances in BMP Receptor Signaling
  Cytokine & Growth Factor Reviews. Oct-Dec, 2009  |   Pubmed ID: 19897402
• Monomeric and Dimeric GDF-5 Show Equal Type I Receptor Binding and Oligomerization Capability and Have the Same Biological Activity
  Biological Chemistry. Apr, 2006  |   Pubmed ID: 16606344
• Activating and Deactivating Mutations in the Receptor Interaction Site of GDF5 Cause Symphalangism or Brachydactyly Type A2
  The Journal of Clinical Investigation. Sep, 2005  |   Pubmed ID: 16127465