Philippe Marin CNRS, UMR-5203 Institut de Génomique Fonctionnelle, Montpellier Biography Publications Institution JoVE Articles Philippe Marin has not added a biography. If you are Philippe Marin and would like to personalize this page please email our Author Liaison for assistance. Publications Salivary Gland Proteome Analysis Reveals Modulation of Anopheline Unique Proteins in Insensitive Acetylcholinesterase Resistant Anopheles Gambiae Mosquitoes PloS One. 2014 | Pubmed ID: 25102176 The Serotonin 6 Receptor Controls Neuronal Migration During Corticogenesis Via a Ligand-independent Cdk5-dependent Mechanism Development (Cambridge, England). Sep, 2014 | Pubmed ID: 25078650 Cdk5 Induces Constitutive Activation of 5-HT6 Receptors to Promote Neurite Growth Nature Chemical Biology. Jul, 2014 | Pubmed ID: 24880860 Quantitative Phosphoproteomics Unravels Biased Phosphorylation of Serotonin 2A Receptor at Ser280 by Hallucinogenic Versus Nonhallucinogenic Agonists Molecular & Cellular Proteomics : MCP. May, 2014 | Pubmed ID: 24637012 Early Administration of RS 67333, a Specific 5-HT4 Receptor Agonist, Prevents Amyloidogenesis and Behavioral Deficits in the 5XFAD Mouse Model of Alzheimer's Disease Frontiers in Aging Neuroscience. 2013 | Pubmed ID: 24399967 CRMP2 Tethers Kainate Receptor Activity to Cytoskeleton Dynamics During Neuronal Maturation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2013 | Pubmed ID: 24227739 Calcineurin Interacts with the Serotonin Transporter C-terminus to Modulate Its Plasma Membrane Expression and Serotonin Uptake The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2013 | Pubmed ID: 24107951 Disruption of 5-HT2A Receptor-PDZ Protein Interactions Alleviates Mechanical Hypersensitivity in Carrageenan-induced Inflammation in Rats PloS One. 2013 | Pubmed ID: 24058620 Angiogenin Induces Modifications in the Astrocyte Secretome: Relevance to Amyotrophic Lateral Sclerosis Journal of Proteomics. Oct, 2013 | Pubmed ID: 23920243 Structure-based Design of PDZ Ligands As Inhibitors of 5-HT(2A) Receptor/PSD-95 PDZ1 Domain Interaction Possessing Anti-hyperalgesic Activity ACS Chemical Biology. Oct, 2013 | Pubmed ID: 23895101 Shank3-Rich2 Interaction Regulates AMPA Receptor Recycling and Synaptic Long-term Potentiation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2013 | Pubmed ID: 23739967 Identification of PDZ Ligands by Docking-based Virtual Screening for the Development of Novel Analgesic Agents Bioorganic & Medicinal Chemistry Letters. May, 2013 | Pubmed ID: 23545111 [The MTOR Pathway: a New Target for Treating Cognitive Deficits of Schizophrenia?] Médecine Sciences : M/S. Jan, 2013 | Pubmed ID: 23351690 5-HT4 Receptors Constitutively Promote the Non-amyloidogenic Pathway of APP Cleavage and Interact with ADAM10 ACS Chemical Neuroscience. Jan, 2013 | Pubmed ID: 23336052 5-HT(6) Receptor Recruitment of MTOR As a Mechanism for Perturbed Cognition in Schizophrenia EMBO Molecular Medicine. Oct, 2012 | Pubmed ID: 23027611 Quantitative Proteomic Analysis Reveals Protein Expression Changes in the Murine Neuronal Secretome During Apoptosis Journal of Proteomics. Dec, 2012 | Pubmed ID: 23009950 Motoneurons Secrete Angiogenin to Induce RNA Cleavage in Astroglia The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2012 | Pubmed ID: 22496549 S32212, a Novel Serotonin Type 2C Receptor Inverse Agonist/α2-adrenoceptor Antagonist and Potential Antidepressant: I. A Mechanistic Characterization The Journal of Pharmacology and Experimental Therapeutics. Mar, 2012 | Pubmed ID: 22178752 5-HT Receptor-associated Protein Networks: New Targets for Drug Discovery in Psychiatric Disorders? Current Drug Targets. Jan, 2012 | Pubmed ID: 21777185 Synthesis and Evaluation of Bidentate Ligands Designed to Interact with PDZ Domains Bioorganic & Medicinal Chemistry. Jul, 2011 | Pubmed ID: 21680189 The Serotonin Transporter is an Exclusive Client of the Coat Protein Complex II (COPII) Component SEC24C The Journal of Biological Chemistry. May, 2011 | Pubmed ID: 21454670 G Protein Activation by Serotonin Type 4 Receptor Dimers: Evidence That Turning on Two Protomers is More Efficient The Journal of Biological Chemistry. Mar, 2011 | Pubmed ID: 21247891 The Melatonergic Agonist and Clinically Active Antidepressant, Agomelatine, is a Neutral Antagonist at 5-HT(2C) Receptors The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). Jul, 2011 | Pubmed ID: 20946699 Techniques for Studying Inverse Agonist Activity of Antidepressants at Recombinant Nonedited 5-HT(₂C-INI) Receptor and Native Neuronal 5-HT(₂C) Receptors Methods in Enzymology. 2010 | Pubmed ID: 21050911 Constitutive Activity of Serotonin 2C Receptors at G Protein-independent Signaling: Modulation by RNA Editing and Antidepressants Molecular Pharmacology. Nov, 2010 | Pubmed ID: 20699324 Disrupting 5-HT(2A) Receptor/PDZ Protein Interactions Reduces Hyperalgesia and Enhances SSRI Efficacy in Neuropathic Pain Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2010 | Pubmed ID: 20531396 Collapsin Response Mediator Protein 4a (CRMP4a) is Upregulated in Motoneurons of Mutant SOD1 Mice and Can Trigger Motoneuron Axonal Degeneration and Cell Death The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2010 | Pubmed ID: 20071543 GPCR Interacting Proteins (GIPs) in the Nervous System: Roles in Physiology and Pathologies Annual Review of Pharmacology and Toxicology. 2010 | Pubmed ID: 20055699 Beta-arrestin1 Phosphorylation by GRK5 Regulates G Protein-independent 5-HT4 Receptor Signalling The EMBO Journal. Sep, 2009 | Pubmed ID: 19661922 Enhanced Detection of CNS Cell Secretome in Plasma Protein-depleted Cerebrospinal Fluid Journal of Proteome Research. Oct, 2008 | Pubmed ID: 18774838 Physical Interaction of Calmodulin with the 5-hydroxytryptamine2C Receptor C-terminus is Essential for G Protein-independent, Arrestin-dependent Receptor Signaling Molecular Biology of the Cell. Nov, 2008 | Pubmed ID: 18768750 Signaling at G-protein-coupled Serotonin Receptors: Recent Advances and Future Research Directions Trends in Pharmacological Sciences. Sep, 2008 | Pubmed ID: 18676031 PICK1 Uncoupling from MGluR7a Causes Absence-like Seizures Nature Neuroscience. Aug, 2008 | Pubmed ID: 18641645 Inverse Agonist and Neutral Antagonist Actions of Antidepressants at Recombinant and Native 5-hydroxytryptamine2C Receptors: Differential Modulation of Cell Surface Expression and Signal Transduction Molecular Pharmacology. Mar, 2008 | Pubmed ID: 18083778 GPCR-jacking: from a New Route in RTK Signalling to a New Concept in GPCR Activation Trends in Pharmacological Sciences. Dec, 2007 | Pubmed ID: 18001849 [When Two Molecules Involved in the Regulation of Mood Meet: Mutual Modulation of the Serotonin Transporter and Neuronal NO-synthase] Médecine Sciences : M/S. May, 2007 | Pubmed ID: 17502079 PACAP Type I Receptor Transactivation is Essential for IGF-1 Receptor Signalling and Antiapoptotic Activity in Neurons The EMBO Journal. Mar, 2007 | Pubmed ID: 17332755 The Proteomic Analysis of Mouse Choroid Plexus Secretome Reveals a High Protein Secretion Capacity of Choroidal Epithelial Cells Proteomics. Nov, 2006 | Pubmed ID: 17051638 Opposite Effects of PSD-95 and MPP3 PDZ Proteins on Serotonin 5-hydroxytryptamine2C Receptor Desensitization and Membrane Stability Molecular Biology of the Cell. Nov, 2006 | Pubmed ID: 16914526 Neuronal 5-HT Metabotropic Receptors: Fine-tuning of Their Structure, Signaling, and Roles in Synaptic Modulation Cell and Tissue Research. Nov, 2006 | Pubmed ID: 16896947 Calpain Product of WT-CRMP2 Reduces the Amount of Surface NR2B NMDA Receptor Subunit Journal of Neurochemistry. Aug, 2006 | Pubmed ID: 16787405 [Proteomic Profiling: the Potential of Seldi-Tof for the Identification of New Cancer Biomarkers] Bulletin Du Cancer. Sep, 2005 | Pubmed ID: 16203265 Co-assembly of Two GluR6 Kainate Receptor Splice Variants Within a Functional Protein Complex Neuron. Aug, 2005 | Pubmed ID: 16102538 Difference in Mass Analysis Using Labeled Lysines (DIMAL-K): a New, Efficient Proteomic Quantification Method Applied to the Analysis of Astrocytic Secretomes Molecular & Cellular Proteomics : MCP. Aug, 2005 | Pubmed ID: 15905179 Proteomic Detection of Prostate-specific Antigen Using a Serum Fractionation Procedure: Potential Implication for New Low-abundance Cancer Biomarkers Detection Analytical Biochemistry. Mar, 2005 | Pubmed ID: 15707932 GPCR-GIP Networks: a First Step in the Discovery of New Therapeutic Drugs? Current Opinion in Drug Discovery & Development. Sep, 2004 | Pubmed ID: 15503867 New Sorting Nexin (SNX27) and NHERF Specifically Interact with the 5-HT4a Receptor Splice Variant: Roles in Receptor Targeting Journal of Cell Science. Oct, 2004 | Pubmed ID: 15466885 GPCR Interacting Proteins (GIP) Pharmacology & Therapeutics. Sep, 2004 | Pubmed ID: 15464590 Molecular and Functional Characterization of Proteins Interacting with the C-terminal Domains of 5-HT2 Receptors: Emergence of 5-HT2 "receptosomes" Biology of the Cell / Under the Auspices of the European Cell Biology Organization. Jun, 2004 | Pubmed ID: 15207907 The Serotonin 5-HT2A and 5-HT2C Receptors Interact with Specific Sets of PDZ Proteins The Journal of Biological Chemistry. May, 2004 | Pubmed ID: 14988405 The 'magic Tail' of G Protein-coupled Receptors: an Anchorage for Functional Protein Networks FEBS Letters. Jul, 2003 | Pubmed ID: 12829238 Proteomic Analysis of Astrocytic Secretion in the Mouse. Comparison with the Cerebrospinal Fluid Proteome The Journal of Biological Chemistry. Jul, 2003 | Pubmed ID: 12709418 A Proteomic Approach Based on Peptide Affinity Chromatography, 2-dimensional Electrophoresis and Mass Spectrometry to Identify Multiprotein Complexes Interacting with Membrane-bound Receptors Biological Procedures Online. Dec, 2002 | Pubmed ID: 12734563 Akt Mediates the Anti-apoptotic Effect of NMDA but Not That Induced by Potassium Depolarization in Cultured Cerebellar Granule Cells The European Journal of Neuroscience. Aug, 2002 | Pubmed ID: 12270033 Synaptic Multiprotein Complexes Associated with 5-HT(2C) Receptors: a Proteomic Approach The EMBO Journal. May, 2002 | Pubmed ID: 12006486 High Performance Two-dimensional Gel Electrophoresis Using a Wetting Agent Tergitol NP7 Proteomics. May, 2002 | Pubmed ID: 11987122 Identification of New Proteins in Follicular Fluid of Mature Human Follicles Electrophoresis. Apr, 2002 | Pubmed ID: 11981869 Synergistic Regulation of Cytosolic Ca2+ Concentration by Adenosine and Alpha1-Adrenergic Agonists in Mouse Striatal Astrocytes The European Journal of Neuroscience. Jun, 1991 | Pubmed ID: 12106486 Primary Culture of Mouse Dopaminergic Neurons Florence Gaven1,2,3, Philippe Marin1,2,3, Sylvie Claeysen1,2,3 1CNRS, UMR-5203, Institut de Génomique Fonctionnelle, Montpellier, 2Inserm, U661, Montpellier, 3Universités de Montpellier JoVE 51751 Neuroscience
Primary Culture of Mouse Dopaminergic Neurons Florence Gaven1,2,3, Philippe Marin1,2,3, Sylvie Claeysen1,2,3 1CNRS, UMR-5203, Institut de Génomique Fonctionnelle, Montpellier, 2Inserm, U661, Montpellier, 3Universités de Montpellier JoVE 51751 Neuroscience