Pinchas Cohen

Publications

• The Mitochondrial-Derived Peptides, HumaninS14G and Small Humanin-like Peptide 2, Exhibit Chaperone-like Activity
  Scientific Reports. Aug, 2017  |   Pubmed ID: 28798389
• Humanin G (HNG) Protects Age-related Macular Degeneration (AMD) Transmitochondrial ARPE-19 Cybrids from Mitochondrial and Cellular Damage
  Cell Death & Disease. Jul, 2017  |   Pubmed ID: 28726777
• The GH Receptor Exon 3 Deletion is a Marker of Male-specific Exceptional Longevity Associated with Increased GH Sensitivity and Taller Stature
  Science Advances. Jun, 2017  |   Pubmed ID: 28630896
• Feeling Misguided: a Comment on the US Guidelines on Growth Hormone and Insulin-like Growth Factor-I Treatment in Children and Adolescents
  Current Opinion in Pediatrics. Aug, 2017  |   Pubmed ID: 28604412
• Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production
  Cell Metabolism. Jun, 2017  |   Pubmed ID: 28591635
• Mitochondrially Derived Peptides As Novel Regulators of Metabolism
  The Journal of Physiology. Jun, 2017  |   Pubmed ID: 28574175
• Mitochondrial DNA Hypomethylation Is a Biomarker Associated with Induced Senescence in Human Fetal Heart Mesenchymal Stem Cells
  Stem Cells International. 2017  |   Pubmed ID: 28484495
• Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes
  Cell. Feb, 2017  |   Pubmed ID: 28235195
• Fasting-mimicking Diet and Markers/risk Factors for Aging, Diabetes, Cancer, and Cardiovascular Disease
  Science Translational Medicine. Feb, 2017  |   Pubmed ID: 28202779
• Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice
  Scientific Reports. Feb, 2017  |   Pubmed ID: 28145503
• Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione
  PloS One. 2016  |   Pubmed ID: 27783653
• Lower Circulating Insulin-like Growth Factor-I is Associated with Better Cognition in Females with Exceptional Longevity Without Compromise to Muscle Mass and Function
  Aging. Oct, 2016  |   Pubmed ID: 27744417
• The Mitochondrial-derived Peptide Humanin Activates the ERK1/2, AKT, and STAT3 Signaling Pathways and Has Age-dependent Signaling Differences in the Hippocampus
  Oncotarget. Jul, 2016  |   Pubmed ID: 27384491
• Effect of Dietary Omega-3 Fatty Acids on Tumor-Associated Macrophages and Prostate Cancer Progression
  The Prostate. Oct, 2016  |   Pubmed ID: 27338236
• Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice
  Cell Metabolism. Jun, 2016  |   Pubmed ID: 27304509
• Safety and Feasibility of Fasting in Combination with Platinum-based Chemotherapy
  BMC Cancer. Jun, 2016  |   Pubmed ID: 27282289
• MOTS-c: A Novel Mitochondrial-derived Peptide Regulating Muscle and Fat Metabolism
  Free Radical Biology & Medicine. Nov, 2016  |   Pubmed ID: 27216708
• Naturally Occurring Mitochondrial-derived Peptides Are Age-dependent Regulators of Apoptosis, Insulin Sensitivity, and Inflammatory Markers
  Aging. Apr, 2016  |   Pubmed ID: 27070352
• Growth Hormone Research Society Perspective on the Development of Long-acting Growth Hormone Preparations
  European Journal of Endocrinology. Jun, 2016  |   Pubmed ID: 27009113
• The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction
  Investigative Ophthalmology & Visual Science. Mar, 2016  |   Pubmed ID: 26990160
• Central Insulin-like Growth Factor-1 (IGF-1) Restores Whole-body Insulin Action in a Model of Age-related Insulin Resistance and IGF-1 Decline
  Aging Cell. Feb, 2016  |   Pubmed ID: 26534869
• The Potent Humanin Analogue (HNG) Protects Germ Cells and Leucocytes While Enhancing Chemotherapy-Induced Suppression of Cancer Metastases in Male Mice
  Endocrinology. Dec, 2015  |   Pubmed ID: 26384090
• Status of Long-acting-growth Hormone Preparations--2015
  Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Oct, 2015  |   Pubmed ID: 26187188
• Rat Humanin is Encoded and Translated in Mitochondria and is Localized to the Mitochondrial Compartment Where It Regulates ROS Production
  Molecular and Cellular Endocrinology. Sep, 2015  |   Pubmed ID: 26116236
• A Periodic Diet That Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan
  Cell Metabolism. Jul, 2015  |   Pubmed ID: 26094889
• The Mitochondrial-derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance
  Cell Metabolism. Mar, 2015  |   Pubmed ID: 25738459
• The Effects of Humanin and Its Analogues on Male Germ Cell Apoptosis Induced by Chemotherapeutic Drugs
  Apoptosis : an International Journal on Programmed Cell Death. Apr, 2015  |   Pubmed ID: 25666707
• The Effect of Sex on Humanin Levels in Healthy Adults and Patients with Uncomplicated Type 1 Diabetes Mellitus
  Canadian Journal of Physiology and Pharmacology. Apr, 2015  |   Pubmed ID: 25615723
• IGF-I Regulates the Age-dependent Signaling Peptide Humanin
  Aging Cell. Oct, 2014  |   Pubmed ID: 25040290
• Low Insulin-like Growth Factor-1 Level Predicts Survival in Humans with Exceptional Longevity
  Aging Cell. Aug, 2014  |   Pubmed ID: 24618355
• Low Protein Intake is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population
  Cell Metabolism. Mar, 2014  |   Pubmed ID: 24606898
• New Role for the Mitochondrial Peptide Humanin: Protective Agent Against Chemotherapy-induced Side Effects
  Journal of the National Cancer Institute. Mar, 2014  |   Pubmed ID: 24586106
• IGF1R Blockade with Ganitumab Results in Systemic Effects on the GH-IGF Axis in Mice
  The Journal of Endocrinology. Apr, 2014  |   Pubmed ID: 24492468
• Dose-sparing and Safety-enhancing Effects of an IGF-I-based Dosing Regimen in Short Children Treated with Growth Hormone in a 2-year Randomized Controlled Trial: Therapeutic and Pharmacoeconomic Considerations
  Clinical Endocrinology. Jul, 2014  |   Pubmed ID: 24428305
• Effect of a Low-fat Fish Oil Diet on Proinflammatory Eicosanoids and Cell-cycle Progression Score in Men Undergoing Radical Prostatectomy
  Cancer Prevention Research (Philadelphia, Pa.). Jan, 2014  |   Pubmed ID: 24169960
• Pharmacokinetics and Tissue Distribution of Humanin and Its Analogues in Male Rodents
  Endocrinology. Oct, 2013  |   Pubmed ID: 23836030
• Effects of Calorie Restriction and IGF-1 Receptor Blockade on the Progression of 22Rv1 Prostate Cancer Xenografts
  International Journal of Molecular Sciences. Jul, 2013  |   Pubmed ID: 23823800
• Prepubertal Children with Growth Hormone Deficiency Treated for Four Years with Growth Hormone Experience Dose-dependent Increase in Height, but Not in the Rate of Puberty Initiation
  Hormone Research in Paediatrics. 2013  |   Pubmed ID: 23816571
• Response of the Insulin-like Growth Factor (IGF) System to IGF-IR Inhibition and Androgen Deprivation in a Neoadjuvant Prostate Cancer Trial: Effects of Obesity and Androgen Deprivation
  The Journal of Clinical Endocrinology and Metabolism. May, 2013  |   Pubmed ID: 23533230
• Humanin: a Harbinger of Mitochondrial-derived Peptides?
  Trends in Endocrinology and Metabolism: TEM. May, 2013  |   Pubmed ID: 23402768
• Protein Restriction Cycles Reduce IGF-1 and Phosphorylated Tau, and Improve Behavioral Performance in an Alzheimer's Disease Mouse Model
  Aging Cell. Apr, 2013  |   Pubmed ID: 23362919
• The Emerging Role of the Mitochondrial-derived Peptide Humanin in Stress Resistance
  Journal of Molecular Endocrinology. Feb, 2013  |   Pubmed ID: 23239898
• Resveratrol Worsens Survival in SCID Mice with Prostate Cancer Xenografts in a Cell-line Specific Manner, Through Paradoxical Effects on Oncogenic Pathways
  The Prostate. May, 2013  |   Pubmed ID: 23192356
• Growth Hormone Receptor (GHR) Exon 3 Polymorphism Status Detection by Dual-enzyme-linked Immunosorbent Assay (ELISA)
  The Journal of Clinical Endocrinology and Metabolism. Jan, 2013  |   Pubmed ID: 23162096
• IGFBP-3 Nuclear Localization Predicts Human Prostate Cancer Recurrence
  Hormones & Cancer. Feb, 2013  |   Pubmed ID: 23011725
• Efficacy of IGF-based Growth Hormone (GH) Dosing in NonGH-deficient (nonGHD) Short Stature Children with Low IGF-I is Not Related to Basal IGF-I Levels
  Clinical Endocrinology. Mar, 2013  |   Pubmed ID: 22924571
• Humanin Prevents Intra-renal Microvascular Remodeling and Inflammation in Hypercholesterolemic ApoE Deficient Mice
  Life Sciences. Sep, 2012  |   Pubmed ID: 22820173
• Effect of a Low-fat Diet Combined with IGF-1 Receptor Blockade on 22Rv1 Prostate Cancer Xenografts
  Molecular Cancer Therapeutics. Jul, 2012  |   Pubmed ID: 22562985
• Humanin, a Cytoprotective Peptide, is Expressed in Carotid Atherosclerotic [corrected] Plaques in Humans
  PloS One. 2012  |   Pubmed ID: 22328926
• 生长激素治疗的长期监测。
  The Journal of Clinical Endocrinology and Metabolism. Jan, 2012  |   Pubmed ID: 22174422
• How Useful Are Serum IGF-I Measurements for Managing GH Replacement Therapy in Adults and Children?
  Pituitary. Jun, 2012  |   Pubmed ID: 21909971
• Phase II Prospective Randomized Trial of a Low-fat Diet with Fish Oil Supplementation in Men Undergoing Radical Prostatectomy
  Cancer Prevention Research (Philadelphia, Pa.). Dec, 2011  |   Pubmed ID: 22027686
• Global Igfbp1 Deletion Does Not Affect Prostate Cancer Development in a C-Myc Transgenic Mouse Model
  The Journal of Endocrinology. Dec, 2011  |   Pubmed ID: 21903863
• Insulin-like Growth Factor (IGF)-I and IGF-II Contribute Differentially to the Phenotype of Pregnancy Associated Plasma Protein-A Knock-out Mice
  Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Oct, 2011  |   Pubmed ID: 21802327
• Humanin Preserves Endothelial Function and Prevents Atherosclerotic Plaque Progression in Hypercholesterolemic ApoE Deficient Mice
  Atherosclerosis. Nov, 2011  |   Pubmed ID: 21763658
• IGFBP-3 is a Metastasis Suppression Gene in Prostate Cancer
  Cancer Research. Aug, 2011  |   Pubmed ID: 21697285
• 生长激素受体缺陷是与主要减少关联 [信号、 癌症和糖尿病的人类。
  Science Translational Medicine. Feb, 2011  |   Pubmed ID: 21325617
• Endocrine Actions of Myostatin: Systemic Regulation of the IGF and IGF Binding Protein Axis
  Endocrinology. Jan, 2011  |   Pubmed ID: 21147879
• Chemoprevention of Prostate Cancer with Lycopene in the TRAMP Model
  The Prostate. Oct, 2010  |   Pubmed ID: 20687227
• Humanin is Expressed in Human Vascular Walls and Has a Cytoprotective Effect Against Oxidized LDL-induced Oxidative Stress
  Cardiovascular Research. Nov, 2010  |   Pubmed ID: 20562421
• Variable Degree of Growth Hormone (GH) and Insulin-like Growth Factor (IGF) Sensitivity in Children with Idiopathic Short Stature Compared with GH-deficient Patients: Evidence from an IGF-based Dosing Study of Short Children
  The Journal of Clinical Endocrinology and Metabolism. May, 2010  |   Pubmed ID: 20207829
• Effect of Intermittent Fasting with or Without Caloric Restriction on Prostate Cancer Growth and Survival in SCID Mice
  The Prostate. Jul, 2010  |   Pubmed ID: 20166128
• 减少水平的胰岛素样生长因子-调解差动保护的正常和肿瘤细胞的禁食的响应，并提高化疗指数。
  Cancer Research. Feb, 2010  |   Pubmed ID: 20145127
• Opposing Roles of Insulin-like Growth Factor Binding Protein 3 and Humanin in the Regulation of Testicular Germ Cell Apoptosis
  Endocrinology. Jan, 2010  |   Pubmed ID: 19952275
• Growth Inhibitory Effect of Low Fat Diet on Prostate Cancer Cells: Results of a Prospective, Randomized Dietary Intervention Trial in Men with Prostate Cancer
  The Journal of Urology. Jan, 2010  |   Pubmed ID: 19914662
• Interaction of Insulin-like Growth Factor-binding Protein-3 and BAX in Mitochondria Promotes Male Germ Cell Apoptosis
  The Journal of Biological Chemistry. Jan, 2010  |   Pubmed ID: 19887447
• Pomegranate Extract Induces Apoptosis in Human Prostate Cancer Cells by Modulation of the IGF-IGFBP Axis
  Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Feb, 2010  |   Pubmed ID: 19853487
• The Neurosurvival Factor Humanin Inhibits Beta-cell Apoptosis Via Signal Transducer and Activator of Transcription 3 Activation and Delays and Ameliorates Diabetes in Nonobese Diabetic Mice
  Metabolism: Clinical and Experimental. Mar, 2010  |   Pubmed ID: 19800083
• 在人类中的禁食和癌症治疗： 案例系列报告。
  Aging. Dec, 2009  |   Pubmed ID: 20157582
• Clinical Management of Growth Hormone Therapy for Children
  Managed Care (Langhorne, Pa.). Aug, 2009  |   Pubmed ID: 19760983
• Growth Hormone Treatment: Evidence, Practice, and Emerging Issues
  Managed Care (Langhorne, Pa.). Aug, 2009  |   Pubmed ID: 19760982
• Humanin: a Novel Central Regulator of Peripheral Insulin Action
  PloS One. 2009  |   Pubmed ID: 19623253
• Enhancing the Apoptotic Potential of Insulin-like Growth Factor-binding Protein-3 in Prostate Cancer by Modulation of CK2 Phosphorylation
  Molecular Endocrinology (Baltimore, Md.). Oct, 2009  |   Pubmed ID: 19556345
• The Effects of Varying Dietary Carbohydrate and Fat Content on Survival in a Murine LNCaP Prostate Cancer Xenograft Model
  Cancer Prevention Research (Philadelphia, Pa.). Jun, 2009  |   Pubmed ID: 19470786
• Liver-specific Deletion of the Growth Hormone Receptor Reveals Essential Role of Growth Hormone Signaling in Hepatic Lipid Metabolism
  The Journal of Biological Chemistry. Jul, 2009  |   Pubmed ID: 19460757
• Optimizing Growth Hormone Dosing in Children with Idiopathic Short Stature
  Hormone Research. Jan, 2009  |   Pubmed ID: 19153511
• PAPA-1 Is a Nuclear Binding Partner of IGFBP-2 and Modulates Its Growth-promoting Actions
  Molecular Endocrinology (Baltimore, Md.). Feb, 2009  |   Pubmed ID: 19095771
• Serum Complexes of Insulin-like Growth Factor-1 Modulate Skeletal Integrity and Carbohydrate Metabolism
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2009  |   Pubmed ID: 18952711
• Surprising New Height Regulating Genes: Beyond Growth Hormone and IGF-I
  Pediatric Research. Nov, 2008  |   Pubmed ID: 18931612
• Lost in Translation?
  Pediatric Research. Sep, 2008  |   Pubmed ID: 18714199
• Homeostatic Imbalance Between Apoptosis and Cell Renewal in the Liver of Premature Aging Xpd Mice
  PloS One. Jun, 2008  |   Pubmed ID: 18545656
• Targeted Deletion of Hepatic Igf1 in TRAMP Mice Leads to Dramatic Alterations in the Circulating Insulin-like Growth Factor Axis but Does Not Reduce Tumor Progression
  Cancer Research. May, 2008  |   Pubmed ID: 18451161
• Statement 1: a Serum Insulin-like Growth Factor I (IGF-I) Level Should Be Part of the Evaluation of Children with Short Stature
  Pediatric Endocrinology Reviews : PER. Apr, 2008  |   Pubmed ID: 18438325
• Effect of Low-fat Diet on Development of Prostate Cancer and Akt Phosphorylation in the Hi-Myc Transgenic Mouse Model
  Cancer Research. Apr, 2008  |   Pubmed ID: 18413778
• SnoRNA Snord116 (Pwcr1/MBII-85) Deletion Causes Growth Deficiency and Hyperphagia in Mice
  PloS One. Mar, 2008  |   Pubmed ID: 18320030
• Functionally Significant Insulin-like Growth Factor I Receptor Mutations in Centenarians
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008  |   Pubmed ID: 18316725
• Carbohydrate Restriction, Prostate Cancer Growth, and the Insulin-like Growth Factor Axis
  The Prostate. Jan, 2008  |   Pubmed ID: 17999389
• Quantitative Ontogeny of Murine Insulin-like Growth Factor (IGF)-I, IGF-binding Protein-3 and the IGF-related Acid-labile Subunit
  Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Feb, 2008  |   Pubmed ID: 17719253
• Dietary Feeding of Silibinin Inhibits Prostate Tumor Growth and Progression in Transgenic Adenocarcinoma of the Mouse Prostate Model
  Cancer Research. Nov, 2007  |   Pubmed ID: 18006855
• The Somatomedin Hypothesis 2007: 50 Years Later
  The Journal of Clinical Endocrinology and Metabolism. Dec, 2007  |   Pubmed ID: 17986643
• A Mechanism to Explain How Regular Exercise Might Reduce the Risk for Clinical Prostate Cancer
  European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP). Oct, 2007  |   Pubmed ID: 17923812
• Spinal Bone Mineral Density, IGF-1 and IGFBP-3 in Children with Cerebral Palsy
  Hormone Research. 2007  |   Pubmed ID: 17912004
• Treatment Perspectives in Idiopathic Short Stature with a Focus on IGF-I Deficiency
  Pediatric Endocrinology Reviews : PER. May, 2007  |   Pubmed ID: 17581497
• 激素调节的蛋白质降解 ′-2 是减毒进展至 LNCaP 级数模型中的雄激素不敏感。
  Journal of Cellular Physiology. Oct, 2007  |   Pubmed ID: 17492783
• Contribution of the Orphan Nuclear Receptor Nur77 to the Apoptotic Action of IGFBP-3
  Carcinogenesis. Aug, 2007  |   Pubmed ID: 17434920
• Insulin Growth Factor-based Dosing of Growth Hormone Therapy in Children: a Randomized, Controlled Study
  The Journal of Clinical Endocrinology and Metabolism. Jul, 2007  |   Pubmed ID: 17356043
• Insulin-like Growth Factor Binding Protein-3 Induces Insulin Resistance in Adipocytes in Vitro and in Rats in Vivo
  Pediatric Research. Feb, 2007  |   Pubmed ID: 17237715
• Growth Hormone Therapy Improves Bone Mineral Density in Children with Cerebral Palsy: a Preliminary Pilot Study
  The Journal of Clinical Endocrinology and Metabolism. Mar, 2007  |   Pubmed ID: 17179200
• Phosphorylation by DNA-dependent Protein Kinase is Critical for Apoptosis Induction by Insulin-like Growth Factor Binding Protein-3
  Cancer Research. Nov, 2006  |   Pubmed ID: 17108124
• Central and Opposing Effects of IGF-I and IGF-binding Protein-3 on Systemic Insulin Action
  Diabetes. Oct, 2006  |   Pubmed ID: 17003344
• Controversy in Clinical Endocrinology: Problems with Reclassification of Insulin-like Growth Factor I Production and Action Disorders
  The Journal of Clinical Endocrinology and Metabolism. Nov, 2006  |   Pubmed ID: 16954153
• Effect of Altering Dietary Omega-6/omega-3 Fatty Acid Ratios on Prostate Cancer Membrane Composition, Cyclooxygenase-2, and Prostaglandin E2
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2006  |   Pubmed ID: 16899616
• Advances in Pediatric Growth Hormone Therapy: IGF-I-based Dosing
  Indian Pediatrics. Jul, 2006  |   Pubmed ID: 16891676
• The Ternary IGF Complex Influences Postnatal Bone Acquisition and the Skeletal Response to Intermittent Parathyroid Hormone
  The Journal of Endocrinology. May, 2006  |   Pubmed ID: 16648296
• Anti-apoptotic Factor Humanin is Expressed in the Testis and Prevents Cell-death in Leydig Cells During the First Wave of Spermatogenesis
  Journal of Cellular Physiology. Aug, 2006  |   Pubmed ID: 16619233
• Insulin-like Growth Factor Binding Protein-3: Insulin-like Growth Factor Independence Comes of Age
  Endocrinology. May, 2006  |   Pubmed ID: 16617154
• Insulin-like Growth Factor Binding Protein 3 As an Anticancer Molecule in Ewing's Sarcoma
  International Journal of Cancer. Sep, 2006  |   Pubmed ID: 16570284
• Overview of the IGF-I System
  Hormone Research. 2006  |   Pubmed ID: 16508327
• Ribonucleic Acid Polymerase II Binding Subunit 3 (Rpb3), a Potential Nuclear Target of Insulin-like Growth Factor Binding Protein-3
  Endocrinology. May, 2006  |   Pubmed ID: 16455777
• Identification of Insulin-like Growth Factor Binding Protein-3 As a Farnesyl Transferase Inhibitor SCH66336-induced Negative Regulator of Angiogenesis in Head and Neck Squamous Cell Carcinoma
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2006  |   Pubmed ID: 16428512
• Racial Differences in Prognostic Value of Adult Height for Biochemical Progression Following Radical Prostatectomy
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2005  |   Pubmed ID: 16278394
• The Role of the Insulin-like Growth Factor System in Prenatal Growth
  Molecular Genetics and Metabolism. Sep-Oct, 2005  |   Pubmed ID: 16165387
• Control of Aging and Longevity by IGF-I Signaling
  Experimental Gerontology. Nov, 2005  |   Pubmed ID: 16154307
• Insulin-like Growth Factor I (IGF-I) Measurements in Growth Hormone (GH) Therapy of Idiopathic Short Stature (ISS)
  Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Jul, 2005  |   Pubmed ID: 16039893
• Combination Therapy of Insulin-like Growth Factor Binding Protein-3 and Retinoid X Receptor Ligands Synergize on Prostate Cancer Cell Apoptosis in Vitro and in Vivo
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2005  |   Pubmed ID: 16000583
• Pharmacodynamic Considerations with Recombinant Human Insulin-like Growth Factor-I in Children
  Hormone Research. 2005  |   Pubmed ID: 15886488
• P53-Dependent and P53-independent Induction of Insulin-like Growth Factor Binding Protein-3 by Deoxyribonucleic Acid Damage and Hypoxia
  The Journal of Clinical Endocrinology and Metabolism. Jun, 2005  |   Pubmed ID: 15769996
• Rapid Apoptosis Induction by IGFBP-3 Involves an Insulin-like Growth Factor-independent Nucleomitochondrial Translocation of RXRalpha/Nur77
  The Journal of Biological Chemistry. Apr, 2005  |   Pubmed ID: 15731112
• Overexpression of Gly56/gly80/gly81-mutant Insulin-like Growth Factor-binding Protein-3 in Transgenic Mice
  Endocrinology. Mar, 2005  |   Pubmed ID: 15550509
• Allelic Differences in a Quantitative Trait Locus Affecting Insulin-like Growth Factor-I Impact Skeletal Acquisition and Body Composition
  Pediatric Nephrology (Berlin, Germany). Mar, 2005  |   Pubmed ID: 15549416
• The Role of Insulin-like Growth Factor I Monitoring in Growth Hormone-treated Children
  Hormone Research. 2004  |   Pubmed ID: 15761234
• Is Treatment with Growth Hormone Effective in Children with Cerebral Palsy?
  Developmental Medicine and Child Neurology. Aug, 2004  |   Pubmed ID: 15287249
• EWS/FLI-1 Silencing and Gene Profiling of Ewing Cells Reveal Downstream Oncogenic Pathways and a Crucial Role for Repression of Insulin-like Growth Factor Binding Protein 3
  Molecular and Cellular Biology. Aug, 2004  |   Pubmed ID: 15282325
• Insulin-like Growth Factor Binding Protein-3 is a Novel Mediator of Apoptosis in Insulin-secreting Cells
  Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Jun, 2004  |   Pubmed ID: 15125883
• Phenotypic Effects of Leptin Replacement on Morbid Obesity, Diabetes Mellitus, Hypogonadism, and Behavior in Leptin-deficient Adults
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004  |   Pubmed ID: 15070752
• Insulin-like Growth Factor Binding Protein-3 Antagonizes the Effects of Retinoids in Myeloid Leukemia Cells
  Blood. Jul, 2004  |   Pubmed ID: 15026318
• Cellular Internalization of Insulin-like Growth Factor Binding Protein-3: Distinct Endocytic Pathways Facilitate Re-uptake and Nuclear Localization
  The Journal of Biological Chemistry. Jan, 2004  |   Pubmed ID: 14576164
• A Functional Genomics Approach for the Identification of Putative Tumor Suppressor Genes: Dickkopf-1 As Suppressor of HeLa Cell Transformation
  Carcinogenesis. Jan, 2004  |   Pubmed ID: 14555616
• Insulin-like Growth Factors and Their Binding Proteins in Children Born Small for Gestational Age: Implication for Growth Hormone Therapy
  Hormone Research. 2003  |   Pubmed ID: 14671408
• Update of Guidelines for the Use of Growth Hormone in Children: the Lawson Wilkins Pediatric Endocrinology Society Drug and Therapeutics Committee
  The Journal of Pediatrics. Oct, 2003  |   Pubmed ID: 14571209
• Interaction Between the Alzheimer's Survival Peptide Humanin and Insulin-like Growth Factor-binding Protein 3 Regulates Cell Survival and Apoptosis
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2003  |   Pubmed ID: 14561895
• Effect of Isocaloric Low-fat Diet on Human LAPC-4 Prostate Cancer Xenografts in Severe Combined Immunodeficient Mice and the Insulin-like Growth Factor Axis
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2003  |   Pubmed ID: 12855654
• Insulin-like Growth Factor I Stimulates Telomerase Activity in Prostate Cancer Cells
  The Journal of Clinical Endocrinology and Metabolism. Jul, 2003  |   Pubmed ID: 12843187
• Individualized Growth Hormone Therapy in Children: Advances Beyond Weight-based Dosing
  Journal of Pediatric Endocrinology & Metabolism : JPEM. May, 2003  |   Pubmed ID: 12795364
• Insulin-like Growth Factor I (IGF-I) and IGF Binding Protein-1 Modulate Prostate Cancer Cell Growth and Apoptosis: Possible Mediators for the Effects of Diet and Exercise on Cancer Cell Survival
  Endocrinology. Jun, 2003  |   Pubmed ID: 12746292
• Type Ialpha Collagen is an IGFBP-3 Binding Protein
  Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Apr-Jun, 2003  |   Pubmed ID: 12735930
• Novel Stimulatory Role for Insulin-like Growth Factor Binding Protein-2 in Prostate Cancer Cells
  International Journal of Cancer. May, 2003  |   Pubmed ID: 12672024
• Rapid Insulin-like Growth Factor (IGF)-independent Effects of IGF Binding Protein-3 on Endothelial Cell Survival
  The Journal of Clinical Endocrinology and Metabolism. Feb, 2003  |   Pubmed ID: 12574231
• Effect of Diet and Exercise on Serum Insulin, IGF-I, and IGFBP-1 Levels and Growth of LNCaP Cells in Vitro (United States)
  Cancer Causes & Control : CCC. Dec, 2002  |   Pubmed ID: 12588089
• IGFs and IGFBPs: Role in Health and Disease
  Best Practice & Research. Clinical Endocrinology & Metabolism. Sep, 2002  |   Pubmed ID: 12464227
• Association Between the Insulin Resistance of Puberty and the Insulin-like Growth Factor-I/growth Hormone Axis
  The Journal of Clinical Endocrinology and Metabolism. Oct, 2002  |   Pubmed ID: 12364479
• Diagnosis and Management of Growth Hormone Deficiency in Childhood and Adolescence--part 2: Growth Hormone Treatment in Growth Hormone Deficient Children
  Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Oct, 2002  |   Pubmed ID: 12213187
• IGFBP-3 Mediates P53-induced Apoptosis During Serum Starvation
  International Journal of Oncology. Aug, 2002  |   Pubmed ID: 12118329
• Insulin-like Growth Factor Binding Protein-3 Inhibits the Growth of Non-small Cell Lung Cancer
  Cancer Research. Jun, 2002  |   Pubmed ID: 12068000
• Insulin-like Growth Factor Binding Protein-3 Mediates Tumor Necrosis Factor-alpha-induced Apoptosis: Role of Bcl-2 Phosphorylation
  Cell Growth & Differentiation : the Molecular Biology Journal of the American Association for Cancer Research. Apr, 2002  |   Pubmed ID: 11971816
• Effects of Dose and Gender on the Growth and Growth Factor Response to GH in GH-deficient Children: Implications for Efficacy and Safety
  The Journal of Clinical Endocrinology and Metabolism. Jan, 2002  |   Pubmed ID: 11788629