Priscille Brodin Inserm U1019 - CNRS UMR 8024, Institut Pasteur de Lille Université de Lille Biography Publications Institution JoVE Articles Priscille Brodin has not added a biography. If you are Priscille Brodin and would like to personalize this page please email our Author Liaison for assistance. Publications Discovery of Q203, a Potent Clinical Candidate for the Treatment of Tuberculosis Nature Medicine. Aug, 2013 | Pubmed ID: 23913123 The Balance of Apoptotic and Necrotic Cell Death in Mycobacterium Tuberculosis Infected Macrophages is Not Dependent on Bacterial Virulence PloS One. 2012 | Pubmed ID: 23118880 Discovery of Novel N-phenylphenoxyacetamide Derivatives As EthR Inhibitors and Ethionamide Boosters by Combining High-throughput Screening and Synthesis Journal of Medicinal Chemistry. Jul, 2012 | Pubmed ID: 22738293 A Novel Specific Edge Effect Correction Method for RNA Interference Screenings Bioinformatics (Oxford, England). Jan, 2012 | Pubmed ID: 22121160 Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-based Drug Design to Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-oxadiazole EthR Inhibitors Journal of Medicinal Chemistry. Jan, 2012 | Pubmed ID: 22098589 Analogous Mechanisms of Resistance to Benzothiazinones and Dinitrobenzamides in Mycobacterium Smegmatis PloS One. 2011 | Pubmed ID: 22069462 High-content Screening in Infectious Diseases Current Opinion in Chemical Biology. Aug, 2011 | Pubmed ID: 21684803 Ethionamide Boosters: Synthesis, Biological Activity, and Structure-activity Relationships of a Series of 1,2,4-oxadiazole EthR Inhibitors Journal of Medicinal Chemistry. Apr, 2011 | Pubmed ID: 21417236 High-content Imaging of Mycobacterium Tuberculosis-infected Macrophages: an in Vitro Model for Tuberculosis Drug Discovery Future Medicinal Chemistry. Aug, 2010 | Pubmed ID: 21426019 High Content Phenotypic Cell-based Visual Screen Identifies Mycobacterium Tuberculosis Acyltrehalose-containing Glycolipids Involved in Phagosome Remodeling PLoS Pathogens. 2010 | Pubmed ID: 20844580 Functional Characterization of the Mycobacterium Tuberculosis Serine/threonine Kinase PknJ Microbiology (Reading, England). Jun, 2010 | Pubmed ID: 20185505 Long-circulating DNA Lipid Nanocapsules As New Vector for Passive Tumor Targeting Biomaterials. Jan, 2010 | Pubmed ID: 19800113 High Content Screening Identifies Decaprenyl-phosphoribose 2' Epimerase As a Target for Intracellular Antimycobacterial Inhibitors PLoS Pathogens. Oct, 2009 | Pubmed ID: 19876393 Systematic Genetic Nomenclature for Type VII Secretion Systems PLoS Pathogens. Oct, 2009 | Pubmed ID: 19876390 Benzothiazinones Kill Mycobacterium Tuberculosis by Blocking Arabinan Synthesis Science (New York, N.Y.). May, 2009 | Pubmed ID: 19299584 Automated High-throughput SiRNA Transfection in Raw 264.7 Macrophages: a Case Study for Optimization Procedure Journal of Biomolecular Screening. Feb, 2009 | Pubmed ID: 19196705 Control of M. Tuberculosis ESAT-6 Secretion and Specific T Cell Recognition by PhoP PLoS Pathogens. Feb, 2008 | Pubmed ID: 18282096 [Aquatic Insects and Transmission of Mycobacterium Ulcerans] Médecine Sciences : M/S. Jun-Jul, 2007 | Pubmed ID: 17631825 ESAT-6 from Mycobacterium Tuberculosis Dissociates from Its Putative Chaperone CFP-10 Under Acidic Conditions and Exhibits Membrane-lysing Activity Journal of Bacteriology. Aug, 2007 | Pubmed ID: 17557817 Impact of Mycobacterium Ulcerans Biofilm on Transmissibility to Ecological Niches and Buruli Ulcer Pathogenesis PLoS Pathogens. May, 2007 | Pubmed ID: 17480118 Protection Against Mycobacterium Ulcerans Lesion Development by Exposure to Aquatic Insect Saliva PLoS Medicine. Feb, 2007 | Pubmed ID: 17326707 Synthesis and Antimycobacterial Evaluation of Benzofurobenzopyran Analogues Bioorganic & Medicinal Chemistry. Mar, 2007 | Pubmed ID: 17208445 Inactivation of Rv2525c, a Substrate of the Twin Arginine Translocation (Tat) System of Mycobacterium Tuberculosis, Increases Beta-lactam Susceptibility and Virulence Journal of Bacteriology. Sep, 2006 | Pubmed ID: 16952959 High Frequency of CD4+ T Cells Specific for the TB10.4 Protein Correlates with Protection Against Mycobacterium Tuberculosis Infection Infection and Immunity. Jun, 2006 | Pubmed ID: 16714570 Benzofuro[3,2-f][1]benzopyrans: a New Class of Antitubercular Agents Bioorganic & Medicinal Chemistry. Aug, 2006 | Pubmed ID: 16616504 An Increase in Antimycobacterial Th1-cell Responses by Prime-boost Protocols of Immunization Does Not Enhance Protection Against Tuberculosis Infection and Immunity. Apr, 2006 | Pubmed ID: 16552042 Dissection of ESAT-6 System 1 of Mycobacterium Tuberculosis and Impact on Immunogenicity and Virulence Infection and Immunity. Jan, 2006 | Pubmed ID: 16368961 Tuberculosis: from Genome to Vaccine Expert Review of Vaccines. Aug, 2005 | Pubmed ID: 16117711 Functional Analysis of Early Secreted Antigenic Target-6, the Dominant T-cell Antigen of Mycobacterium Tuberculosis, Reveals Key Residues Involved in Secretion, Complex Formation, Virulence, and Immunogenicity The Journal of Biological Chemistry. Oct, 2005 | Pubmed ID: 16048998 Immunogenic Membrane-associated Proteins of Mycobacterium Tuberculosis Revealed by Proteomics Microbiology (Reading, England). Jul, 2005 | Pubmed ID: 16000731 Influence of ESAT-6 Secretion System 1 (RD1) of Mycobacterium Tuberculosis on the Interaction Between Mycobacteria and the Host Immune System Journal of Immunology (Baltimore, Md. : 1950). Mar, 2005 | Pubmed ID: 15749894 結核のモルモットエアロゾル感染モデルを用いたEUの結核ワクチンのクラスタでのワクチンの評価 Tuberculosis (Edinburgh, Scotland). Jan-Mar, 2005 | Pubmed ID: 15687025 ESAT-6 Proteins: Protective Antigens and Virulence Factors? Trends in Microbiology. Nov, 2004 | Pubmed ID: 15488391 Enhanced Protection Against Tuberculosis by Vaccination with Recombinant Mycobacterium Microti Vaccine That Induces T Cell Immunity Against Region of Difference 1 Antigens The Journal of Infectious Diseases. Jul, 2004 | Pubmed ID: 15195250 Cell Envelope Protein PPE68 Contributes to Mycobacterium Tuberculosis RD1 Immunogenicity Independently of a 10-kilodalton Culture Filtrate Protein and ESAT-6 Infection and Immunity. Apr, 2004 | Pubmed ID: 15039340 Macro-array and Bioinformatic Analyses Reveal Mycobacterial 'core' Genes, Variation in the ESAT-6 Gene Family and New Phylogenetic Markers for the Mycobacterium Tuberculosis Complex Microbiology (Reading, England). Feb, 2004 | Pubmed ID: 14766927 CD8+-T-cell Responses of Mycobacterium-infected Mice to a Newly Identified Major Histocompatibility Complex Class I-restricted Epitope Shared by Proteins of the ESAT-6 Family Infection and Immunity. Dec, 2003 | Pubmed ID: 14638811 Recombinant BCG Exporting ESAT-6 Confers Enhanced Protection Against Tuberculosis Nature Medicine. May, 2003 | Pubmed ID: 12692540 Loss of RD1 Contributed to the Attenuation of the Live Tuberculosis Vaccines Mycobacterium Bovis BCG and Mycobacterium Microti Molecular Microbiology. Nov, 2002 | Pubmed ID: 12410828 Bacterial Artificial Chromosome-based Comparative Genomic Analysis Identifies Mycobacterium Microti As a Natural ESAT-6 Deletion Mutant Infection and Immunity. Oct, 2002 | Pubmed ID: 12228284 Disruption of HIV-1 Integrase-DNA Complexes by Short 6-oxocytosine-containing Oligonucleotides Biochemistry. Feb, 2002 | Pubmed ID: 11814346 高スループット/高含有スクリーニングに適応した細胞内マイコバクテリアの定量化のための顕微鏡表現型アッセイ Christophe. J Queval*1, Ok-Ryul Song*1, Vincent Delorme*1, Raffaella Iantomasi1, Romain Veyron-Churlet1, Nathalie Deboosère1, Valérie Landry1, Alain Baulard1, Priscille Brodin1 1Inserm U1019 - CNRS UMR 8024, Institut Pasteur de Lille, Université de Lille JoVE 51114 Immunology and Infection
高スループット/高含有スクリーニングに適応した細胞内マイコバクテリアの定量化のための顕微鏡表現型アッセイ Christophe. J Queval*1, Ok-Ryul Song*1, Vincent Delorme*1, Raffaella Iantomasi1, Romain Veyron-Churlet1, Nathalie Deboosère1, Valérie Landry1, Alain Baulard1, Priscille Brodin1 1Inserm U1019 - CNRS UMR 8024, Institut Pasteur de Lille, Université de Lille JoVE 51114 Immunology and Infection