Qing Li Department of Internal Medicine University of Michigan, Ann Arbor Biography Publications Institution JoVE Articles Qing Li has not added a biography. If you are Qing Li and would like to personalize this page please email our Author Liaison for assistance. Publications Oncogenic N-Ras Mitigates Oxidative Stress-Induced Apoptosis of Hematopoietic Stem Cells Cancer Research. 03, 2021 | Pubmed ID: 33441311 The Emerging Role of Ras Pathway Signaling in Pediatric Cancer Cancer Research. 12, 2020 | Pubmed ID: 32907837 Allosteric Modulation of the Catalytic VYD Loop in Slingshot by Its N-terminal Domain Underlies Both Slingshot Auto-inhibition and Activation The Journal of Biological Chemistry. Oct, 2018 | Pubmed ID: 30154244 Allosteric Mechanisms Underlie GPCR Signaling to SH3-domain Proteins Through Arrestin Nature Chemical Biology. Sep, 2018 | Pubmed ID: 30120361 Prevalence and Risk Factors for Fatigue Among Breast Cancer Survivors on Aromatase Inhibitors European Journal of Cancer (Oxford, England : 1990). Sep, 2018 | Pubmed ID: 30014974 Unraveling the Mechanical Unfolding Pathways of a Multidomain Protein: Phosphoglycerate Kinase Biophysical Journal. Jul, 2018 | Pubmed ID: 29972811 A HER2 Bispecific Antibody Can Be Efficiently Expressed in with Potent Cytotoxicity Oncology Letters. Jul, 2018 | Pubmed ID: 29963199 Site-specific PEGylation of an Anti-CEA/CD3 Bispecific Antibody Improves Its Antitumor Efficacy International Journal of Nanomedicine. 2018 | Pubmed ID: 29881272 Ablation of Somatostatin Cells Leads to Impaired Pancreatic Islet Function and Neonatal Death in Rodents Cell Death & Disease. Jun, 2018 | Pubmed ID: 29880854 Cyanidin-3-o-β-Glucoside Induces Megakaryocyte Apoptosis Via PI3K/Akt- and MAPKs-Mediated Inhibition of NF-κB Signalling Thrombosis and Haemostasis. Jul, 2018 | Pubmed ID: 29864778 A Targeted Transforming Growth Factor-beta (TGF-β) Blocker, TTB, Inhibits Tumor Growth and Metastasis Oncotarget. May, 2018 | Pubmed ID: 29796175 A Single Domain-Based Anti-Her2 Antibody Has Potent Antitumor Activities Translational Oncology. Apr, 2018 | Pubmed ID: 29455083 Surface-Assisted Alkane Polymerization: Investigation on Structure-Reactivity Relationship Journal of the American Chemical Society. 04, 2018 | Pubmed ID: 29432011 Ultrasonic RF Time Series for Early Assessment of the Tumor Response to Chemotherapy Oncotarget. Jan, 2018 | Pubmed ID: 29416800 Single Domain Based Bispecific Antibody, Muc1-Bi-1, and Its Humanized Form, Muc1-Bi-2, Induce Potent Cancer Cell Killing in Muc1 Positive Tumor Cells PloS One. 2018 | Pubmed ID: 29357376 Assessment of the Cardiac Safety Between Cetuximab and Panitumumab As Single Therapy in Chinese Chemotherapy-refractory MCRC OncoTargets and Therapy. 2018 | Pubmed ID: 29343971 Barriers to Acupuncture Use Among Breast Cancer Survivors: A Cross-Sectional Analysis Integrative Cancer Therapies. 09, 2018 | Pubmed ID: 29338443 A Bispecific Antibody Based on Pertuzumab Fab Has Potent Antitumor Activity Journal of Immunotherapy (Hagerstown, Md. : 1997). Jan, 2018 | Pubmed ID: 29232309 An SNP Panel for the Analysis of Paternally Inherited Alleles in Maternal Plasma Using Ion Torrent PGM International Journal of Legal Medicine. Mar, 2018 | Pubmed ID: 28429088 Generation of Special Autosomal Dominant Polycystic Kidney Disease IPSCs with the Capability of Functional Kidney-like Cell Differentiation Stem Cell Research & Therapy. Sep, 2017 | Pubmed ID: 28927462 Lower Plasma Fetuin-A Levels Are Associated With a Higher Mortality Risk in Patients With Coronary Artery Disease Arteriosclerosis, Thrombosis, and Vascular Biology. 11, 2017 | Pubmed ID: 28912366 Associations Between Serum Calcium, Phosphorus and Mortality Among Patients with Coronary Heart Disease European Journal of Nutrition. Aug, 2017 | Pubmed ID: 28808770 BiHC, a T-Cell-Engaging Bispecific Recombinant Antibody, Has Potent Cytotoxic Activity Against Her2 Tumor Cells Translational Oncology. Oct, 2017 | Pubmed ID: 28797938 Identification of Novel Proteins Interacting with Vascular Endothelial Growth Inhibitor 174 in Renal Cell Carcinoma Anticancer Research. 08, 2017 | Pubmed ID: 28739731 Crystal Structure and Thermostability Characterization of Enterovirus D68 3D Journal of Virology. 09, 2017 | Pubmed ID: 28659472 Vascular Endothelial Growth Inhibitor 174 and Its Functional Domains Inhibit Epithelial-mesenchymal Transition in Renal Cell Carcinoma Cells In vitro International Journal of Molecular Medicine. Aug, 2017 | Pubmed ID: 28656288 A Cullin 4B-RING E3 Ligase Complex Fine-tunes Pancreatic δ Cell Paracrine Interactions The Journal of Clinical Investigation. Jun, 2017 | Pubmed ID: 28604389 Intra-tumour Molecular Heterogeneity of Clear Cell Renal Cell Carcinoma Reveals the Diversity of the Response to Targeted Therapies Using Patient-derived Xenograft Models Oncotarget. Jul, 2017 | Pubmed ID: 28548943 N-3 Polyunsaturated Fatty Acids Increase Hepatic Fibroblast Growth Factor 21 Sensitivity Via a PPAR-γ-β-klotho Pathway Molecular Nutrition & Food Research. Sep, 2017 | Pubmed ID: 28371258 Vascular Endothelial Growth Inhibitor, a Cytokine of the Tumor Necrosis Factor Family, is Associated With Epithelial-Mesenchymal Transition in Renal Cell Carcinoma Applied Immunohistochemistry & Molecular Morphology : AIMM. Mar, 2017 | Pubmed ID: 28362712 Retinol Binding Protein-4 Levels and Non-alcoholic Fatty Liver Disease: A Community-based Cross-sectional Study Scientific Reports. Mar, 2017 | Pubmed ID: 28332619 Fish Oil Supplementation Inhibits Endoplasmic Reticulum Stress and Improves Insulin Resistance: Involvement of AMP-activated Protein Kinase Food & Function. Apr, 2017 | Pubmed ID: 28327709 Noninvasive Fetal Genotyping of Paternally Inherited Alleles Using Targeted Massively Parallel Sequencing in Parentage Testing Cases Transfusion. 06, 2017 | Pubmed ID: 28295384 Cobalt Chloride-induced Hypoxia Induces Epithelial-mesenchymal Transition in Renal Carcinoma Cell Lines Annals of Clinical and Laboratory Science. Jan, 2017 | Pubmed ID: 28249915 Erratum To: 53BP1 Depletion Causes PARP Inhibitor Resistance in ATM-deficient Breast Cancer Cells BMC Cancer. 11, 2016 | Pubmed ID: 27899080 Prediction of the Risk of Mortality Using Risk Score in Patients with Coronary Heart Disease Oncotarget. Dec, 2016 | Pubmed ID: 27835576 Association Between Serum Fibroblast Growth Factor 21 and Mortality Among Patients With Coronary Artery Disease The Journal of Clinical Endocrinology and Metabolism. 12, 2016 | Pubmed ID: 27662438 Single Domain Antibody-based Bispecific Antibody Induces Potent Specific Anti-tumor Activity Cancer Biology & Therapy. 12, 2016 | Pubmed ID: 27645568 53BP1 Depletion Causes PARP Inhibitor Resistance in ATM-deficient Breast Cancer Cells BMC Cancer. 09, 2016 | Pubmed ID: 27613518 Metabolic Syndrome and Its Individual Components with Mortality Among Patients with Coronary Heart Disease International Journal of Cardiology. Dec, 2016 | Pubmed ID: 27599384 Estimated Glomerular Filtration Rate and Mortality Among Patients with Coronary Heart Disease PloS One. 2016 | Pubmed ID: 27537335 SPARC Overexpression in Primary Tumors Correlates with Disease Recurrence and Overall Survival in Patients with Triple Negative Breast Cancer Oncotarget. 11, 2016 | Pubmed ID: 27421134 Single-molecule Force Spectroscopy Reveals the Calcium Dependence of the Alternative Conformations in the Native State of a βγ-Crystallin Protein The Journal of Biological Chemistry. 08, 2016 | Pubmed ID: 27378818 Bispecific Antibodies in Cancer Immunotherapy Human Vaccines & Immunotherapeutics. 10, 2016 | Pubmed ID: 27249163 In vitro CAPE Inhibitory Activity Towards Human AKR1C3 and the Molecular Basis Chemico-biological Interactions. Jun, 2016 | Pubmed ID: 27163852 Noncoding Transcription Is a Driving Force for Nucleosome Instability in Spt16 Mutant Cells Molecular and Cellular Biology. 07, 2016 | Pubmed ID: 27141053 A Single-domain Antibody-linked Fab Bispecific Antibody Her2-S-Fab Has Potent Cytotoxicity Against Her2-expressing Tumor Cells AMB Express. Dec, 2016 | Pubmed ID: 27112931 Cholesterol Efflux Capacity is an Independent Predictor of All-cause and Cardiovascular Mortality in Patients with Coronary Artery Disease: A Prospective Cohort Study Atherosclerosis. 06, 2016 | Pubmed ID: 27088866 Research on Supporting Mounts of Spheres in Measurement of Gravitational Constant G The Review of Scientific Instruments. Mar, 2016 | Pubmed ID: 27036796 Association Between Serum Uric Acid and Mortality Among Chinese Patients with Coronary Artery Disease Cardiology. 2016 | Pubmed ID: 26985667 A Novel Bispecific Antibody, BiSS, with Potent Anti-cancer Activities Cancer Biology & Therapy. 04, 2016 | Pubmed ID: 26828900 Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) During Catalysis The Journal of Biological Chemistry. Mar, 2016 | Pubmed ID: 26797133 Contamination and Distribution of Heavy Metals, Polybrominated Diphenyl Ethers and Alternative Halogenated Flame Retardants in a Pristine Mangrove Marine Pollution Bulletin. Feb, 2016 | Pubmed ID: 26759186 In Vitro Inhibition of Glyoxalase І by Flavonoids: New Insights from Crystallographic Analysis Current Topics in Medicinal Chemistry. 2016 | Pubmed ID: 26268338 Two New Glycosides Isolated from Sapindus Mukorossi Fruits: Effects on Cell Apoptosis and Caspase-3 Activation in Human Lung Carcinoma Cells Natural Product Research. Jul, 2016 | Pubmed ID: 26158392 National Consensus in China on Diagnosis and Treatment of Patients with Advanced Breast Cancer Annals of Translational Medicine. Oct, 2015 | Pubmed ID: 26605288 Prodrug AST-003 Improves the Therapeutic Index of the Multi-Targeted Tyrosine Kinase Inhibitor Sunitinib PloS One. 2015 | Pubmed ID: 26513662 A Novel Bispecific Antibody, S-Fab, Induces Potent Cancer Cell Killing Journal of Immunotherapy (Hagerstown, Md. : 1997). Nov-Dec, 2015 | Pubmed ID: 26448579 Characterization and Machine Learning Prediction of Allele-specific DNA Methylation Genomics. Dec, 2015 | Pubmed ID: 26407641 The Degree of Contrast Washout on Contrast-Enhanced Ultrasound in Distinguishing Intrahepatic Cholangiocarcinoma from Hepatocellular Carcinoma Ultrasound in Medicine & Biology. Dec, 2015 | Pubmed ID: 26386477 In vitro Inhibition of AKR1Cs by Sulphonylureas and the Structural Basis Chemico-biological Interactions. Oct, 2015 | Pubmed ID: 26362498 Structural Basis for 18-β-glycyrrhetinic Acid As a Novel Non-GSH Analog Glyoxalase I Inhibitor Acta Pharmacologica Sinica. Sep, 2015 | Pubmed ID: 26279158 A Targeted IL-15 Fusion Protein with Potent Anti-tumor Activity Cancer Biology & Therapy. 2015 | Pubmed ID: 26176990 Surgical Strategy for Hepatocellular Carcinoma Patients with Portal/Hepatic Vein Tumor Thrombosis PloS One. 2015 | Pubmed ID: 26076461 Dose-response Relationship in Cisplatin-treated Breast Cancer Xenografts Monitored with Dynamic Contrast-enhanced Ultrasound BMC Cancer. Mar, 2015 | Pubmed ID: 25884471 Functional Evolution of Phosphatidylethanolamine Binding Proteins in Soybean and Arabidopsis The Plant Cell. Feb, 2015 | Pubmed ID: 25663621 Tumor-induced Myeloid-derived Suppressor Cells Promote Tumor Progression Through Oxidative Metabolism in Human Colorectal Cancer Journal of Translational Medicine. Feb, 2015 | Pubmed ID: 25638150 Relationship of Karyotype to Embryo Crown-rump Length and Maternal Serum Human Chorionic Gonadotropin Level in Early Miscarriage American Journal of Perinatology. Jan, 2015 | Pubmed ID: 24705969 Capturing the Mechanical Unfolding Pathway of a Large Protein with Coiled-coil Probes Angewandte Chemie (International Ed. in English). Dec, 2014 | Pubmed ID: 25339429 A Strategy for Fabricating Nanoporous Gold Films Through Chemical Dealloying of Electrochemically Deposited Au-Sn Alloys Nanotechnology. Nov, 2014 | Pubmed ID: 25325248 Determination of Sunitinib and Its Active Metabolite, N-desethyl Sunitinib in Mouse Plasma and Tissues by UPLC-MS/MS: Assay Development and Application to Pharmacokinetic and Tissue Distribution Studies Biomedical Chromatography : BMC. Oct, 2014 | Pubmed ID: 25294592 Structure of Human Endonuclease V As an Inosine-specific Ribonuclease Acta Crystallographica. Section D, Biological Crystallography. Sep, 2014 | Pubmed ID: 25195743 Divalent Metal Ion-based Catalytic Mechanism of the Nudix Hydrolase Orf153 (YmfB) from Escherichia Coli Acta Crystallographica. Section D, Biological Crystallography. May, 2014 | Pubmed ID: 24816099 MicroRNA Profiling Implies New Markers of Chemoresistance of Triple-negative Breast Cancer PloS One. 2014 | Pubmed ID: 24788655 Structural Basis for the Inhibition of AKR1B10 by Caffeic Acid Phenethyl Ester (CAPE) ChemMedChem. Apr, 2014 | Pubmed ID: 24436249 Single Molecule Mechanical Manipulation for Studying Biological Properties of Proteins, DNA, and Sugars Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. May-Jun, 2014 | Pubmed ID: 24347439 The Effect of a Telephone Follow-up Intervention on Illness Perception and Lifestyle After Myocardial Infarction in China: a Randomized Controlled Trial International Journal of Nursing Studies. Jun, 2014 | Pubmed ID: 24211192 Enantioselective Synthesis of Axially Chiral Multifunctionalized Biaryls Via Asymmetric Suzuki-Miyaura Coupling Organic Letters. Nov, 2013 | Pubmed ID: 24138017 Inhibitor Selectivity Between Aldo-keto Reductase Superfamily Members AKR1B10 and AKR1B1: Role of Trp112 (Trp111) FEBS Letters. Nov, 2013 | Pubmed ID: 24100137 Zopolrestat As a Human Glyoxalase I Inhibitor and Its Structural Basis ChemMedChem. Sep, 2013 | Pubmed ID: 23857942 Highly Efficient Synthesis of Heterocyclic and Alicyclic β2-amino Acid Derivatives by Catalytic Asymmetric Hydrogenation Chemistry, an Asian Journal. Sep, 2013 | Pubmed ID: 23776190 Highly Efficient Synthesis of a Class of Novel Chiral-bridged Atropisomeric Monophosphine Ligands Via Simple Desymmetrization and Their Applications in Asymmetric Suzuki-Miyaura Coupling Reaction Organic Letters. Apr, 2012 | Pubmed ID: 22482994 SZ-685C, a Marine Anthraquinone, is a Potent Inducer of Apoptosis with Anticancer Activity by Suppression of the Akt/FOXO Pathway British Journal of Pharmacology. Feb, 2010 | Pubmed ID: 20128807 Serum Uric Acid Levels and Neuromyelitis Optica Journal of Neurology. Jun, 2010 | Pubmed ID: 20094725 [A Comparison of Three Methods in Establishing Transplanted Model of VX2 Tongue Carcinoma in Rabbits] Hua Xi Kou Qiang Yi Xue Za Zhi = Huaxi Kouqiang Yixue Zazhi = West China Journal of Stomatology. Jun, 2009 | Pubmed ID: 19637489 [Exploration of Lymphangiogenesis in Alkali Burned Human Cornea] [Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology. Feb, 2009 | Pubmed ID: 19573329 [Cytotoxicity of the Secondary Metabolites of Marine Mangrove Fungus Paecilomyces Sp. Tree 1-7 on Human Hepatoma Cell Line HepG2] Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials. Jun, 2008 | Pubmed ID: 18998570 [E1A Gene Transfection of Human Undifferentiated Thyroid Cancer Cell Line HTC/3 by Nanoparticles] Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology]. Dec, 2007 | Pubmed ID: 18478924 [Study of the Difference of Ocular Surface Change and Restoration After Two Correction Surgeries of Congenital Ptosis] Yan Ke Xue Bao = Eye Science. Dec, 2007 | Pubmed ID: 18303670 [Changes of Corneal Endothelium Morphology and Thickness After Secondary Intraocular Lens Implantation of Traumatic Aphakia] Yan Ke Xue Bao = Eye Science. Jun, 2007 | Pubmed ID: 17867513 The Influence of Central Corneal Thickness and Corneal Curvature and Axial Length on the Measurement of Intraocular Pressure Yan Ke Xue Bao = Eye Science. Sep, 2002 | Pubmed ID: 15510750 Évaluation de la bioénergétique cellulaire dans les cellules souches hématopoïétiques et progénitrices primitives de souris à l’aide de l’analyseur de flux extracellulaire Surinder Kumar1, Morgan Jones2, Qing Li2,3,4, David B. Lombard1,4,5 1Department of Pathology, University of Michigan, Ann Arbor, 2Department of Internal Medicine, University of Michigan, Ann Arbor, 3Department of Cellular and Developmental Biology, University of Michigan, Ann Arbor, 4Rogel Cancer Center, University of Michigan, Ann Arbor, 5Institute of Gerontology, University of Michigan, Ann Arbor JoVE 63045 Biology Spectroscopie de force unique de molécules de protéines à l’aide d’un Microscope à Force atomique Zackary N. Scholl1, Qing Li1, Eric Josephs1, Dimitra Apostolidou1, Piotr E. Marszalek1 1Mechanical Engineering and Materials Science, Duke University JoVE 55989 Biochemistry Un ciblage GPC3 anticorps bispécifiques, GPC3-S-Fab, avec puissante cytotoxicité Yanlan Wang1,2, Jiayu Liu1,2, Haitao Pan1,2, Jieyu Xing1,2, Xiaoqiong Wu1,2, Qing Li1,2, Zhong Wang1,2 1School of Pharmaceutical Sciences, Sun Yat-Sen University, 2Center for Cellular & Structural Biology, Sun Yat-Sen University JoVE 57588 Cancer Research
Évaluation de la bioénergétique cellulaire dans les cellules souches hématopoïétiques et progénitrices primitives de souris à l’aide de l’analyseur de flux extracellulaire Surinder Kumar1, Morgan Jones2, Qing Li2,3,4, David B. Lombard1,4,5 1Department of Pathology, University of Michigan, Ann Arbor, 2Department of Internal Medicine, University of Michigan, Ann Arbor, 3Department of Cellular and Developmental Biology, University of Michigan, Ann Arbor, 4Rogel Cancer Center, University of Michigan, Ann Arbor, 5Institute of Gerontology, University of Michigan, Ann Arbor JoVE 63045 Biology
Spectroscopie de force unique de molécules de protéines à l’aide d’un Microscope à Force atomique Zackary N. Scholl1, Qing Li1, Eric Josephs1, Dimitra Apostolidou1, Piotr E. Marszalek1 1Mechanical Engineering and Materials Science, Duke University JoVE 55989 Biochemistry
Un ciblage GPC3 anticorps bispécifiques, GPC3-S-Fab, avec puissante cytotoxicité Yanlan Wang1,2, Jiayu Liu1,2, Haitao Pan1,2, Jieyu Xing1,2, Xiaoqiong Wu1,2, Qing Li1,2, Zhong Wang1,2 1School of Pharmaceutical Sciences, Sun Yat-Sen University, 2Center for Cellular & Structural Biology, Sun Yat-Sen University JoVE 57588 Cancer Research
