Qingsheng Li School of Biological Sciences and Nebraska Center for Virology University of Nebraska-Lincoln Biography Publications Institution JoVE Articles Qingsheng LiProfessor Dr. Qingsheng Li is a full professor at the School of Biological Sciences and the Nebraska Center for Virology in University of Nebraska-Lincoln, USA. He is a member of American Association for the Advancement of Science (AAAS), American Associate of Immunologists (AAI), International Society for Vaccines (ISV) and American Society for Virology (ASV). Dr. Li also services as the editorial board member of Current HIV Research, Scientific Report and Virology Journal. He has over 25 years of experience in studying HIV-1 transmission, pathogenesis, microbicide, and vaccine and curative strategy development. Dr. Li’s technical expertise includes the use of SIV-rhesus macaque model, human specimens, humanized-BLT (bone marrow liver and thymus) mouse model, and single-cell in situ analyses. Dr. Li has published 87 peer-reviewed papers, including one paper in Science and two papers in Nature and three papers in Proceedings of the National Academy of Sciences (PNAS). Further, Dr. Li is the principal investigator or co-investigator on many NIH funded grants, including P01, U19, Martin Delaney, R01 and R21 grants. Additionally, Dr. Li has mentored and trained many graduate students and post-doctoral fellows. Publications Detecting the Dynamic Linkage Between Landscape Characteristics and Water Quality in a Subtropical Coastal Watershed, Southeast China Environmental Management. Nov, 2011 | Pubmed ID: 22120882 A Central Role for MTOR Kinase in Homeostatic Proliferation Induced CD8+ T Cell Memory and Tumor Immunity Immunity. Apr, 2011 | Pubmed ID: 21511183 Morphine Potentiates Neuropathogenesis of SIV Infection in Rhesus Macaques Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Dec, 2011 | Pubmed ID: 21431470 Challenges and Counter Challenges in HIV/AIDS Chinese Medical Journal. Dec, 2010 | Pubmed ID: 22166517 Uncertainties in Stormwater Runoff Data Collection from a Small Urban Catchment, Southeast China Journal of Environmental Sciences (China). Month, 2010 | Pubmed ID: 21235157 Differences in HIV Burden and Immune Activation Within the Gut of HIV-positive Patients Receiving Suppressive Antiretroviral Therapy The Journal of Infectious Diseases. Nov, 2010 | Pubmed ID: 20939732 Host Genes Associated with HIV-1 Replication in Lymphatic Tissue Journal of Immunology (Baltimore, Md. : 1950). Nov, 2010 | Pubmed ID: 20935203 Fine-tuning CD8(+) T Cell Functional Responses: MTOR Acts As a Rheostat for Regulating CD8(+) T Cell Proliferation, Survival and Differentiation? Cell Cycle (Georgetown, Tex.). Aug, 2010 | Pubmed ID: 20699660 Tc17 Cells Are Capable of Mediating Immunity to Vaccinia Virus by Acquisition of a Cytotoxic Phenotype Journal of Immunology (Baltimore, Md. : 1950). Aug, 2010 | Pubmed ID: 20624947 AIDS and Optic Neuritis in a Rhesus Monkey Infected with the R5 Clade C SHIV-1157ipd3N4 Journal of Medical Primatology. Oct, 2010 | Pubmed ID: 20412378 The MTOR Kinase Determines Effector Versus Memory CD8+ T Cell Fate by Regulating the Expression of Transcription Factors T-bet and Eomesodermin Immunity. Jan, 2010 | Pubmed ID: 20060330 Regulating Functional Cell Fates in CD8 T Cells Immunologic Research. Mar, 2010 | Pubmed ID: 19859830 Antigen-induced Erk1/2 Activation Regulates Ets-1-mediated Sensitization of CD8+ T Cells for IL-12 Responses Journal of Leukocyte Biology. Feb, 2010 | Pubmed ID: 19843578 Global Genomic Analysis Reveals Rapid Control of a Robust Innate Response in SIV-infected Sooty Mangabeys The Journal of Clinical Investigation. Dec, 2009 | Pubmed ID: 19959874 Microarray Analysis of Lymphatic Tissue Reveals Stage-specific, Gene Expression Signatures in HIV-1 Infection Journal of Immunology (Baltimore, Md. : 1950). Aug, 2009 | Pubmed ID: 19596987 Visualizing Antigen-specific and Infected Cells in Situ Predicts Outcomes in Early Viral Infection Science (New York, N.Y.). Mar, 2009 | Pubmed ID: 19325114 Glycerol Monolaurate Prevents Mucosal SIV Transmission Nature. Apr, 2009 | Pubmed ID: 19262509 Genital Ulcers Facilitate Rapid Viral Entry and Dissemination Following Intravaginal Inoculation with Cell-associated Simian Immunodeficiency Virus SIVmac239 Journal of Virology. Apr, 2008 | Pubmed ID: 18272571 Simian Immunodeficiency Virus-induced Intestinal Cell Apoptosis is the Underlying Mechanism of the Regenerative Enteropathy of Early Infection The Journal of Infectious Diseases. Feb, 2008 | Pubmed ID: 18199035 Characterizing Host Immune Responses by Monitoring Fluorescently Marked Cells Immunological Investigations. Month, 2007 | Pubmed ID: 18161529 IL-12-programmed Long-term CD8+ T Cell Responses Require STAT4 Journal of Immunology (Baltimore, Md. : 1950). Dec, 2006 | Pubmed ID: 17114431 Aspergillus Fumigatus Extract Differentially Regulates Antigen-specific CD4+ and CD8+ T Cell Responses to Promote Host Immunity Journal of Leukocyte Biology. Sep, 2006 | Pubmed ID: 16793916 Premature Induction of an Immunosuppressive Regulatory T Cell Response During Acute Simian Immunodeficiency Virus Infection The Journal of Infectious Diseases. Mar, 2006 | Pubmed ID: 16453267 Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-induced T Regulatory Cells and T-cell Anergy in Tumor-bearing Host Cancer Research. Jan, 2006 | Pubmed ID: 16424049 Potential Roles of Follicular Dendritic Cell-associated Osteopontin in Lymphoid Follicle Pathology and Repair and in B Cell Regulation in HIV-1 and SIV Infection The Journal of Infectious Diseases. Oct, 2005 | Pubmed ID: 16136472 Propagation and Dissemination of Infection After Vaginal Transmission of Simian Immunodeficiency Virus Journal of Virology. Jul, 2005 | Pubmed ID: 15994816 Peak SIV Replication in Resting Memory CD4+ T Cells Depletes Gut Lamina Propria CD4+ T Cells Nature. Apr, 2005 | Pubmed ID: 15793562 IL-21 Enhances and Sustains CD8+ T Cell Responses to Achieve Durable Tumor Immunity: Comparative Evaluation of IL-2, IL-15, and IL-21 Journal of Immunology (Baltimore, Md. : 1950). Jul, 2004 | Pubmed ID: 15240677 Regulation of Dendritic Cell Function by NK Cells: Mechanisms Underlying the Synergism in the Combination Therapy of IL-12 and 4-1BB Activation Journal of Immunology (Baltimore, Md. : 1950). Apr, 2004 | Pubmed ID: 15067054 Roles of Substrate Availability and Infection of Resting and Activated CD4+ T Cells in Transmission and Acute Simian Immunodeficiency Virus Infection Proceedings of the National Academy of Sciences of the United States of America. Apr, 2004 | Pubmed ID: 15064398 NK and CD8+ T Cell-mediated Eradication of Poorly Immunogenic B16-F10 Melanoma by the Combined Action of IL-12 Gene Therapy and 4-1BB Costimulation International Journal of Cancer. Journal International Du Cancer. Apr, 2004 | Pubmed ID: 14991570 Role of Immature Myeloid Gr-1+ Cells in the Development of Antitumor Immunity Cancer Research. Feb, 2004 | Pubmed ID: 14871848 Functional Genomic Analysis of the Response of HIV-1-infected Lymphatic Tissue to Antiretroviral Therapy The Journal of Infectious Diseases. Feb, 2004 | Pubmed ID: 14767808 In Situ Recruitment of Antigen-presenting Cells by Intratumoral GM-CSF Gene Delivery Cancer Immunology, Immunotherapy : CII. Jan, 2004 | Pubmed ID: 12955480 안정된 인간과 같은 장내 미생물군유전체와 인간 면역 체계를 특징으로 하는 이중 인간화 BLT 마우스 모델 Lance Daharsh1,2, Jianshui Zhang1,2, Amanda Ramer-Tait3, Qingsheng Li1,2 1Nebraska Center for Virology, 2School of Biological Sciences, University of Nebraska-Lincoln, 3Department of Food Science and Technology, University of Nebraska-Lincoln JoVE 59773 Biochemistry 주요 조직 적합성 복잡한 클래스 II Dextramers을 사용하여 뇌와 심장에있는자가 반응 CD4 T 세포의 제자리 탐지에 Chandirasegaran Massilamany1, Arunakumar Gangaplara1, Ting Jia1, Christian Elowsky2, Qingsheng Li3, You Zhou2, Jay Reddy1 1School of Veterinary Medicine and Biomedical Sciences, University of Nebraska, Lincoln, 2Center for Biotechnology, University of Nebraska, Lincoln, 3Nebraska Center for Virology and School of Biological Sciences, University of Nebraska, Lincoln JoVE 51679 Immunology and Infection 동시에 바이러스 특정 CD8 + T 세포 바이러스에 감염된 세포를 시각화하는 기술 현장에서 Qingsheng Li1, Pamela J. Skinner2, Lijie Duan1, Ashley T. Haase1 1Department of Microbiology, Medical School, University of Minnesota, 2Department of Veterinary and Biomedical Sciences, University of Minnesota JoVE 1561 Biology
안정된 인간과 같은 장내 미생물군유전체와 인간 면역 체계를 특징으로 하는 이중 인간화 BLT 마우스 모델 Lance Daharsh1,2, Jianshui Zhang1,2, Amanda Ramer-Tait3, Qingsheng Li1,2 1Nebraska Center for Virology, 2School of Biological Sciences, University of Nebraska-Lincoln, 3Department of Food Science and Technology, University of Nebraska-Lincoln JoVE 59773 Biochemistry
주요 조직 적합성 복잡한 클래스 II Dextramers을 사용하여 뇌와 심장에있는자가 반응 CD4 T 세포의 제자리 탐지에 Chandirasegaran Massilamany1, Arunakumar Gangaplara1, Ting Jia1, Christian Elowsky2, Qingsheng Li3, You Zhou2, Jay Reddy1 1School of Veterinary Medicine and Biomedical Sciences, University of Nebraska, Lincoln, 2Center for Biotechnology, University of Nebraska, Lincoln, 3Nebraska Center for Virology and School of Biological Sciences, University of Nebraska, Lincoln JoVE 51679 Immunology and Infection
동시에 바이러스 특정 CD8 + T 세포 바이러스에 감염된 세포를 시각화하는 기술 현장에서 Qingsheng Li1, Pamela J. Skinner2, Lijie Duan1, Ashley T. Haase1 1Department of Microbiology, Medical School, University of Minnesota, 2Department of Veterinary and Biomedical Sciences, University of Minnesota JoVE 1561 Biology
