Qun Lu

Publications

• Nanoarchitecture and Molecular Interactions of Epithelial Cell Junction Proteins Revealed by Super-resolution Microscopy
  Annals of the New York Academy of Sciences. Jul, 2022  |   Pubmed ID: 35819053
• TRPV4: En RhoA To a Cure?
  BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. 06, 2022  |   Pubmed ID: 35441721
• The Effect of Exercise on Early Sensorimotor Performance Alterations in the 3xTg-AD Model of Alzheimer's Disease
  Neuroscience Research. May, 2022  |   Pubmed ID: 35033583
• Pharmacological Modulators of Small GTPases of Rho Family in Neurodegenerative Diseases
  Frontiers in Cellular Neuroscience. 2021  |   Pubmed ID: 34054432
• Selective Axonal Translation of the MRNA Isoform Encoding Prenylated Cdc42 Supports Axon Growth
  Journal of Cell Science. 04, 2021  |   Pubmed ID: 33674450
• Intratumor δ-catenin Heterogeneity Driven by Genomic Rearrangement Dictates Growth Factor Dependent Prostate Cancer Progression
  Oncogene. 05, 2020  |   Pubmed ID: 32313227
• Tight Junction Protein Claudin-7 Is Essential for Intestinal Epithelial Stem Cell Self-Renewal and Differentiation
  Cellular and Molecular Gastroenterology and Hepatology. 2020  |   Pubmed ID: 31874254
• Therapeutic Effect of Y-27632 on Tumorigenesis and Cisplatin-Induced Peripheral Sensory Loss Through RhoA-NF-κB
  Molecular Cancer Research : MCR. 09, 2019  |   Pubmed ID: 31189689
• Claudin-7 Modulates Cell-matrix Adhesion That Controls Cell Migration, Invasion and Attachment of Human HCC827 Lung Cancer Cells
  Oncology Letters. Mar, 2019  |   Pubmed ID: 30854065
• Inhibition of Cdc42-intersectin Interaction by Small Molecule ZCL367 Impedes Cancer Cell Cycle Progression, Proliferation, Migration, and Tumor Growth
  Cancer Biology & Therapy. 2019  |   Pubmed ID: 30849276
• The Effects of Exercise on Hypothalamic Neurodegeneration of Alzheimer's Disease Mouse Model
  PloS One. 2018  |   Pubmed ID: 29293568
• Epithelial Mesenchymal Transition in Embryonic Development, Tissue Repair and Cancer: A Comprehensive Overview
  Journal of Clinical Medicine. Dec, 2017  |   Pubmed ID: 29271928
• Rho GTPases As Therapeutic Targets in Alzheimer's Disease
  Alzheimer's Research & Therapy. Dec, 2017  |   Pubmed ID: 29246246
• Cdc42 Signaling Pathway Inhibition As a Therapeutic Target in Ras- Related Cancers
  Current Medicinal Chemistry. 2017  |   Pubmed ID: 28571533
• Genetic Alterations of δ-catenin/NPRAP/Neurojungin (CTNND2): Functional Implications in Complex Human Diseases
  Human Genetics. 10, 2016  |   Pubmed ID: 27380241
• Early Alterations in Blood and Brain RANTES and MCP-1 Expression and the Effect of Exercise Frequency in the 3xTg-AD Mouse Model of Alzheimer's Disease
  Neuroscience Letters. Jan, 2016  |   Pubmed ID: 26547034
• A Non-tight Junction Function of Claudin-7-Interaction with Integrin Signaling in Suppressing Lung Cancer Cell Proliferation and Detachment
  Molecular Cancer. Jun, 2015  |   Pubmed ID: 26081244
• δ-Catenin, a Wnt/β-catenin Modulator, Reveals Inducible Mutagenesis Promoting Cancer Cell Survival Adaptation and Metabolic Reprogramming
  Oncogene. Mar, 2015  |   Pubmed ID: 24727894
• Amelioration of Cisplatin-induced Experimental Peripheral Neuropathy by a Small Molecule Targeting P75 NTR
  Neurotoxicology. Dec, 2014  |   Pubmed ID: 25277379
• δ-Catenin As a Potential Cancer Biomarker
  Pathology International. May, 2014  |   Pubmed ID: 24888779
• VASP Activation Via the Gα13/RhoA/PKA Pathway Mediates Cucurbitacin-B-induced Actin Aggregation and Cofilin-actin Rod Formation
  PloS One. 2014  |   Pubmed ID: 24691407
• Cytotoxicity of Cyclometalated Platinum Complexes Based on Tridentate NCN and CNN-coordinating Ligands: Remarkable Coordination Dependence
  Journal of Inorganic Biochemistry. May, 2014  |   Pubmed ID: 24531534
• C-Src-mediated Phosphorylation of δ-catenin Increases Its Protein Stability and the Ability of Inducing Nuclear Distribution of β-catenin
  Biochimica Et Biophysica Acta. Apr, 2014  |   Pubmed ID: 24412473
• Claudins in Intestines: Distribution and Functional Significance in Health and Diseases
  Tissue Barriers. Jul, 2013  |   Pubmed ID: 24478939
• The Claudin Family of Proteins in Human Malignancy: a Clinical Perspective
  Cancer Management and Research. Nov, 2013  |   Pubmed ID: 24232410
• 14-3-3É›/ζ Affects the Stability of δ-catenin and Regulates δ-catenin-induced Dendrogenesis
  FEBS Open Bio. 2013  |   Pubmed ID: 23772369
• Claudin-7 Increases Chemosensitivity to Cisplatin Through the Upregulation of Caspase Pathway in Human NCI-H522 Lung Cancer Cells
  Cancer Science. May, 2013  |   Pubmed ID: 23433123
• Small Molecule Targeting Cdc42-intersectin Interaction Disrupts Golgi Organization and Suppresses Cell Motility
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2013  |   Pubmed ID: 23284167
• δ-Catenin Promotes E-cadherin Processing and Activates β-catenin-mediated Signaling: Implications on Human Prostate Cancer Progression
  Biochimica Et Biophysica Acta. Jan, 2012  |   Pubmed ID: 22261283
• Inflammation and Disruption of the Mucosal Architecture in Claudin-7-deficient Mice
  Gastroenterology. Feb, 2012  |   Pubmed ID: 22044670
• Claudin-7 Inhibits Human Lung Cancer Cell Migration and Invasion Through ERK/MAPK Signaling Pathway
  Experimental Cell Research. Aug, 2011  |   Pubmed ID: 21641901
• Hydroxycamptothecin-loaded Fe3O4 Nanoparticles Induce Human Lung Cancer Cell Apoptosis Through Caspase-8 Pathway Activation and Disrupt Tight Junctions
  Cancer Science. Jun, 2011  |   Pubmed ID: 21435100
• Fe3O4 Nanoparticles with Daunorubicin Induce Apoptosis Through Caspase 8-PARP Pathway and Inhibit K562 Leukemia Cell-induced Tumor Growth in Vivo
  Nanomedicine : Nanotechnology, Biology, and Medicine. Oct, 2011  |   Pubmed ID: 21333751
• Human Homolog of Drosophila Hairy and Enhancer of Split 1, Hes1, Negatively Regulates δ-catenin (CTNND2) Expression in Cooperation with E2F1 in Prostate Cancer
  Molecular Cancer. Nov, 2010  |   Pubmed ID: 21106062
• Alzheimer's Disease-linked Presenilin Mutation (PS1M146L) Induces Filamin Expression and γ-secretase Independent Redistribution
  Journal of Alzheimer's Disease : JAD. 2010  |   Pubmed ID: 20847418
• δ-Catenin Dysregulation in Cancer: Interactions with E-cadherin and Beyond
  The Journal of Pathology. Oct, 2010  |   Pubmed ID: 20715154
• Delta-catenin/NPRAP: A New Member of the Glycogen Synthase Kinase-3beta Signaling Complex That Promotes Beta-catenin Turnover in Neurons
  Journal of Neuroscience Research. Aug, 2010  |   Pubmed ID: 20623542
• Pro-oncogenic and Anti-oncogenic Pathways: Opportunities and Challenges of Cancer Therapy
  Future Oncology (London, England). Apr, 2010  |   Pubmed ID: 20373871
• Delta-catenin Affects the Localization and Stability of P120-catenin by Competitively Interacting with E-cadherin
  Molecules and Cells. Mar, 2010  |   Pubmed ID: 20108168
• Isoform- and Dose-sensitive Feedback Interactions Between Paired Box 6 Gene and Delta-catenin in Cell Differentiation and Death
  Experimental Cell Research. Apr, 2010  |   Pubmed ID: 20074565
• Rho Kinase Inhibitor Y-27632 Facilitates Recovery from Experimental Peripheral Neuropathy Induced by Anti-cancer Drug Cisplatin
  Neurotoxicology. Mar, 2010  |   Pubmed ID: 20060419
• Renal Salt Wasting and Chronic Dehydration in Claudin-7-deficient Mice
  American Journal of Physiology. Renal Physiology. Jan, 2010  |   Pubmed ID: 19759267
• Xenopus Delta-catenin is Essential in Early Embryogenesis and is Functionally Linked to Cadherins and Small GTPases
  Journal of Cell Science. Nov, 2009  |   Pubmed ID: 19843587
• GSK-3 Phosphorylates Delta-catenin and Negatively Regulates Its Stability Via Ubiquitination/proteosome-mediated Proteolysis
  The Journal of Biological Chemistry. Oct, 2009  |   Pubmed ID: 19706605
• Analysis of Claudin Genes in Pediatric Patients with Bartter's Syndrome
  Annals of the New York Academy of Sciences. May, 2009  |   Pubmed ID: 19538297
• Signaling Through Rho GTPase Pathway As Viable Drug Target
  Current Medicinal Chemistry. 2009  |   Pubmed ID: 19355891
• Methodology to Obtain a Mixed Sural Nerve Recording in Mice
  American Journal of Physical Medicine & Rehabilitation / Association of Academic Physiatrists. Jul, 2009  |   Pubmed ID: 19325459
• Delta-Catenin Promotes Prostate Cancer Cell Growth and Progression by Altering Cell Cycle and Survival Gene Profiles
  Molecular Cancer. 2009  |   Pubmed ID: 19284555
• Increased DJ-1 Expression Under Oxidative Stress and in Alzheimer's Disease Brains
  Molecular Neurodegeneration. Feb, 2009  |   Pubmed ID: 19243613
• Identification of Extracellular Delta-catenin Accumulation for Prostate Cancer Detection
  The Prostate. Mar, 2009  |   Pubmed ID: 19116988
• Increased Nucleotide Polymorphic Changes in the 5'-untranslated Region of Delta-catenin (CTNND2) Gene in Prostate Cancer
  Oncogene. Jan, 2009  |   Pubmed ID: 18978817
• Small Molecule, Non-peptide P75 Ligands Inhibit Abeta-induced Neurodegeneration and Synaptic Impairment
  PloS One. 2008  |   Pubmed ID: 18978948
• E-Cadherin Negatively Modulates Delta-catenin-induced Morphological Changes and RhoA Activity Reduction by Competing with P190RhoGEF for Delta-catenin
  Biochemical and Biophysical Research Communications. Dec, 2008  |   Pubmed ID: 18930028
• Anti-cancer Drug Induced Neurotoxicity and Identification of Rho Pathway Signaling Modulators As Potential Neuroprotectants
  Neurotoxicology. Jul, 2008  |   Pubmed ID: 18539332
• Identification of E2F1 As a Positive Transcriptional Regulator for Delta-catenin
  Biochemical and Biophysical Research Communications. May, 2008  |   Pubmed ID: 18302937
• Delta-catenin-induced Dendritic Morphogenesis. An Essential Role of P190RhoGEF Interaction Through Akt1-mediated Phosphorylation
  The Journal of Biological Chemistry. Jan, 2008  |   Pubmed ID: 17993462
• WNK4 Phosphorylates Ser(206) of Claudin-7 and Promotes Paracellular Cl(-) Permeability
  FEBS Letters. Aug, 2007  |   Pubmed ID: 17651736
• Presenilin-1 Inhibits Delta-catenin-induced Cellular Branching and Promotes Delta-catenin Processing and Turnover
  Biochemical and Biophysical Research Communications. Dec, 2006  |   Pubmed ID: 17097608
• Increased Expression of Delta-catenin/neural Plakophilin-related Armadillo Protein is Associated with the Down-regulation and Redistribution of E-cadherin and P120ctn in Human Prostate Cancer
  Human Pathology. Oct, 2005  |   Pubmed ID: 16226102
• Overexpression of Claudin-7 Decreases the Paracellular Cl- Conductance and Increases the Paracellular Na+ Conductance in LLC-PK1 Cells
  Journal of Cell Science. Jun, 2005  |   Pubmed ID: 15928046
• Abl Tyrosine Kinase Promotes Dendrogenesis by Inducing Actin Cytoskeletal Rearrangements in Cooperation with Rho Family Small GTPases in Hippocampal Neurons
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2004  |   Pubmed ID: 15456825
• Association of Nonreceptor Tyrosine Kinase C-yes with Tight Junction Protein Occludin by Coimmunoprecipitation Assay
  Methods in Molecular Biology (Clifton, N.J.). 2003  |   Pubmed ID: 12616717
• Dendrite-like Process Formation and Cytoskeletal Remodeling Regulated by Delta-catenin Expression
  Experimental Cell Research. May, 2002  |   Pubmed ID: 11969288
• Nonreceptor Tyrosine Kinase C-Yes Interacts with Occludin During Tight Junction Formation in Canine Kidney Epithelial Cells
  Molecular Biology of the Cell. Apr, 2002  |   Pubmed ID: 11950934