Rashmi Kothary Regenerative Medicine Program Ottawa Hospital Research Institute Biography Publications Institution JoVE Articles Rashmi Kothary has not added a biography. If you are Rashmi Kothary and would like to personalize this page please email our Author Liaison for assistance. Publications More Than a Bystander: the Contributions of Intrinsic Skeletal Muscle Defects in Motor Neuron Diseases Frontiers in Physiology. 2013 | Pubmed ID: 24391590 Transgenic Expression of Neuronal Dystonin Isoform 2 Partially Rescues the Disease Phenotype of the Dystonia Musculorum Mouse Model of Hereditary Sensory Autonomic Neuropathy VI Human Molecular Genetics. Dec, 2013 | Pubmed ID: 24381311 Early Onset Muscle Weakness and Disruption of Muscle Proteins in Mouse Models of Spinal Muscular Atrophy Skeletal Muscle. 2013 | Pubmed ID: 24119341 Supraphysiological Expression of Survival Motor Neuron Protein from an Adenovirus Vector Does Not Adversely Affect Cell Function Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Aug, 2013 | Pubmed ID: 23859020 Six1 Regulates MyoD Expression in Adult Muscle Progenitor Cells PloS One. 2013 | Pubmed ID: 23840772 Distinct Roles for Ste20-like Kinase SLK in Muscle Function and Regeneration Skeletal Muscle. 2013 | Pubmed ID: 23815977 Integrin-Linked Kinase Regulates Process Extension in Oligodendrocytes Via Control of Actin Cytoskeletal Dynamics The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2013 | Pubmed ID: 23739974 Cellular and Molecular Biology of Neuronal Dystonin International Review of Cell and Molecular Biology. 2013 | Pubmed ID: 23273860 A Novel Function for the Survival Motoneuron Protein As a Translational Regulator Human Molecular Genetics. Feb, 2013 | Pubmed ID: 23136128 Defects in Neuromuscular Junction Remodelling in the Smn(2B/-) Mouse Model of Spinal Muscular Atrophy Neurobiology of Disease. Aug, 2012 | Pubmed ID: 22960106 Glucose Metabolism and Pancreatic Defects in Spinal Muscular Atrophy Annals of Neurology. Aug, 2012 | Pubmed ID: 22926856 A Novel Role for the Cytoskeletal Linker Protein Dystonin in the Maintenance of Microtubule Stability and the Regulation of ER-Golgi Transport Bioarchitecture. Jan, 2012 | Pubmed ID: 22754620 The Rb/E2F Pathway Modulates Neurogenesis Through Direct Regulation of the Dlx1/Dlx2 Bigene Cluster The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2012 | Pubmed ID: 22699903 Untethering the Nuclear Envelope and Cytoskeleton: Biologically Distinct Dystonias Arising from a Common Cellular Dysfunction International Journal of Cell Biology. 2012 | Pubmed ID: 22611399 Microtubule Stability, Golgi Organization, and Transport Flux Require Dystonin-a2-MAP1B Interaction The Journal of Cell Biology. Mar, 2012 | Pubmed ID: 22412020 Fasudil Improves Survival and Promotes Skeletal Muscle Development in a Mouse Model of Spinal Muscular Atrophy BMC Medicine. 2012 | Pubmed ID: 22397316 A Novel Whole-cell Lysate Kinase Assay Identifies Substrates of the P38 MAPK in Differentiating Myoblasts Skeletal Muscle. 2012 | Pubmed ID: 22394512 神经元 Dystonin 鼻息肉 2 是内质网结构和功能的调解人。 Molecular Biology of the Cell. Feb, 2012 | Pubmed ID: 22190742 在小鼠发号施令发病的关联不同的神经肌肉接头病理中间脊髓性肌萎缩症表型临界 Smn 阈值。 Neuromuscular Disorders : NMD. Nov, 2011 | Pubmed ID: 22071333 Cre/loxp 序列重组重组要交换对腺病毒衣壳蛋白九单元格绑定图案的使用。 Virology. Nov, 2011 | Pubmed ID: 21968200 MAP1B 和网格蛋白是小说巨细胞-链接器 Dystonin 的相互作用伙伴。 Journal of Proteome Research. Nov, 2011 | Pubmed ID: 21936565 肌激酶抑制: 蛋白激酶哺乳动物骨骼肌成肌的关键。 Skeletal Muscle. 2011 | Pubmed ID: 21902831 马达装置异常的肌张力障碍 Musculorum 小鼠。 PloS One. 2011 | Pubmed ID: 21698255 整合素信号在少突胶质细胞和及其在中枢神经系统髓鞘的重要性。 Journal of Signal Transduction. 2011 | Pubmed ID: 21637375 髓鞘蛋白启动子驱动器之外少突胶质细胞沿袭胚胎和早期发育过程的表达式。 PloS One. 2011 | Pubmed ID: 21572962 生化、 蛋白质组学、 结构和热力学刻画的整合素连接激酶 (ILK): 交叉验证的假激酶结构。 The Journal of Biological Chemistry. Jun, 2011 | Pubmed ID: 21524996 Wnt11 促进规范 Wnt 信号介导半胱氨酸蛋白酶抑制心肌细胞的发展。 Molecular and Cellular Biology. Jan, 2011 | Pubmed ID: 21041481 Smn 缺原因 Neuritogenesis 与神经缺陷小鼠模型的脊髓性肌萎缩症的视网膜神经细胞。 Developmental Neurobiology. Feb, 2011 | Pubmed ID: 20862739 在发展中,但不是晚,模仿 SMN2 拼接和是诱导小鼠生存运动神经元等位基因早救援胚胎致死率。 PloS One. 2010 | Pubmed ID: 21249120 腺病毒载体通过遗传融合单链或单域抗体的衣壳蛋白九重定目标。 Journal of Virology. Oct, 2010 | Pubmed ID: 20631131 肌张力障碍 Musculorum 小鼠心肌中的显示正常的形态学和组织学特征,但显示心脏压力的迹象。 PloS One. 2010 | Pubmed ID: 20209123 SMN 使用串联亲和纯化技术的新型相互作用蛋白伙伴的标识。 Journal of Proteome Research. Apr, 2010 | Pubmed ID: 20201562 用 Perivitelline 空间一个细胞阶段的胚胎干细胞注入小鼠嵌合体的生产。 Transgenic Research. Dec, 2010 | Pubmed ID: 20143261 Rho 激酶灭活延长生存的中间的 SMA 小鼠模型。 Human Molecular Genetics. Apr, 2010 | Pubmed ID: 20097679 神经发育的小鼠模型的脊髓性肌萎缩症 Smn 枯竭的后果。 Journal of Neuroscience Research. Jan, 2010 | Pubmed ID: 19642194 小鼠足细胞特异表达野生型 α-actinin-4 是健康控件的 K256E-α-actinin-4 基因突变转基因小鼠。 Transgenic Research. Apr, 2010 | Pubmed ID: 19585264 Cdx2 调节后通过非 Hox 的目标发展。 Development (Cambridge, England). Dec, 2009 | Pubmed ID: 19906845 刘斌 1 SRC 同源 3 域作为支架的肌纤维肌节大会。 The Journal of Biological Chemistry. Oct, 2009 | Pubmed ID: 19633357 SMN 前国际投资协定和 Plastin 3,: 肌动蛋白动力学的放松管制和 SMA 发病之间的链接。 Molecular and Cellular Neurosciences. Sep, 2009 | Pubmed ID: 19497369 蛋白激酶催化域中的守恒的水分子的作用。 Proteins. Aug, 2009 | Pubmed ID: 19425109 Dystonin/Bpag1 是感觉神经元的必要内质网/核膜蛋白。 Experimental Cell Research. Sep, 2008 | Pubmed ID: 18638474 SMNDelta7 通读产品赋予与 SMNDelta7 蛋白的功能。 Neuroscience Letters. Sep, 2008 | Pubmed ID: 18601974 SMN 耗竭小鼠神经源性神经干细胞在神经发育异常。 Journal of Neuroscience Research. Oct, 2008 | Pubmed ID: 18521935 养护、 多变性和活性蛋白激酶的建模。 PloS One. 2007 | Pubmed ID: 17912359 Smn 消耗改变 Profilin II 表达和 RhoA/岩通路上调导致和神经元完整性的缺陷。 Journal of Molecular Neuroscience : MN. 2007 | Pubmed ID: 17873296 Dystonin/Bpag1 — — 链接到什么? Cell Motility and the Cytoskeleton. Dec, 2007 | Pubmed ID: 17849487 Re:"可能细胞机制的肌张力障碍 Musculorum (dt) 小鼠背根神经节的神经元丢失"。 Journal of Neuropathology and Experimental Neurology. Mar, 2007 | Pubmed ID: 17356386 Cardiomyoblasts MEF2 活性的干扰抑制 Cardiomyogenesis。 Journal of Cell Science. Oct, 2006 | Pubmed ID: 17003108 增强鼠标抗肌萎缩蛋白肌/子 Mdx 转基因小鼠中的驱动器的迷你抗肌萎缩蛋白的表达和营救这些小鼠不良的。 Molecular Therapy : the Journal of the American Society of Gene Therapy. Nov, 2006 | Pubmed ID: 16807118 显性负 Beta1 整合素小鼠具有激酶活性改变时伴随的特定区域的髓鞘缺陷。 Glia. Jun, 2006 | Pubmed ID: 16575886 肌张力障碍 Musculorum 感觉神经元贩卖大分子和细胞器是正常的。 The Journal of Comparative Neurology. Feb, 2006 | Pubmed ID: 16374799 Bpag1 鼻息肉参与细胞骨架在原子核周围的组织。 Experimental Cell Research. Jan, 2006 | Pubmed ID: 16289082 在 Bpag1 轨迹 Dt 小鼠和它们对谈话内容表达影响的基因改变。 Mammalian Genome : Official Journal of the International Mammalian Genome Society. Dec, 2005 | Pubmed ID: 16341670 Hypomorphic Smn 击倒 C2C12 成肌细胞显示成肌细胞融合和骨骼肌形态的内在缺陷。 Experimental Cell Research. Nov, 2005 | Pubmed ID: 16219305 在转基因小鼠模型中表示基因型 1a 丙型肝炎病毒核心和信封蛋白 1 和 2 的肝组织病理学的表征。 The Journal of General Virology. Aug, 2005 | Pubmed ID: 16033966 1.3 Kb 启动子片段赋予 Utrophin 在小鼠骨骼肌纤维的 MRNA 的时空的表达。 Neuromuscular Disorders : NMD. Jun, 2005 | Pubmed ID: 15907291 视网膜感光细胞的生理成熟取决于电压门控钠通道 NaV1.6 (Scn8a)。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2005 | Pubmed ID: 15901786 积极激酶蛋白质组学筛查显示型心肌病的新型信号复杂性。 Molecular & Cellular Proteomics : MCP. May, 2005 | Pubmed ID: 15722372 血影重复细胞核中的蛋白质。 BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Feb, 2005 | Pubmed ID: 15666356 需要维修的哺乳动物 Neuroretinal 身份 Mitf Chx10 镇压。 Development (Cambridge, England). Jan, 2005 | Pubmed ID: 15576400 鼠标抗肌萎缩蛋白肌肉增强剂-1 传授骨骼肌,但不是心脏肌肉、 表达转基因小鼠的抗肌萎缩蛋白浦肯启动子上。 Human Molecular Genetics. Nov, 2004 | Pubmed ID: 15385445 Bpag1 本地化肌动蛋白丝和核心被受其 N 总站。 Journal of Cell Science. Nov, 2003 | Pubmed ID: 14576348 坐骨神经从肌张力障碍 Musculorum 小鼠神经元受损快速轴突运输。 Journal of Neurochemistry. Aug, 2003 | Pubmed ID: 12859670 恢复生存运动神经元蛋白表达的基因治疗策略发展: 影响脊髓性肌萎缩治疗。 Human Gene Therapy. Jan, 2003 | Pubmed ID: 12614569 激活自然杀手受体 Ly49H 的转基因表达赋予易感基因小鼠巨细胞病毒的抗性。 The Journal of Experimental Medicine. Feb, 2003 | Pubmed ID: 12591908 肌张力障碍 Musculorum 小鼠骨骼肌源性的主成肌细胞的分化潜能。 Differentiation; Research in Biological Diversity. Aug, 2002 | Pubmed ID: 12190986 转基因表达和在面板中的自己-1 启动子 Cre 转基因小鼠 Cre 重组酶活性的表征。 Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jun, 2002 | Pubmed ID: 12112467 肌张力障碍 Musculorum 小鼠中枢神经系统髓鞘变化。 Journal of Neuroscience Research. Jul, 2002 | Pubmed ID: 12111805 鼠标抗肌萎缩蛋白增强优先目标 LacZ 在肌肉骨骼和心脏中的表达。 Developmental Dynamics : an Official Publication of the American Association of Anatomists. May, 2002 | Pubmed ID: 11984871 SRp30c 依赖于刺激的生存运动神经元 (SMN) 外显子 7 列入促进了与 HTra2 Beta 1 的直接交互的。 Human Molecular Genetics. Mar, 2002 | Pubmed ID: 11875052 从 ATRX 表达转基因小鼠所引起的神经发育缺陷。 Human Molecular Genetics. Feb, 2002 | Pubmed ID: 11823444 全山神经肌肉交界分析的 横向解剖阿布多米尼斯 肌肉 Lyndsay Murray1, Thomas H Gillingwater2, Rashmi Kothary1 1Regenerative Medicine Program, Ottawa Hospital Research Institute, 2Centre for Integrative Physiology, University of Edinburgh JoVE 51162 Neuroscience 丰富的少突胶质细胞培养和Myelinating产后小鼠组织联合培养的少突胶质细胞/神经元的推导 Ryan W. O'Meara1,2, Scott D. Ryan1, Holly Colognato3, Rashmi Kothary1,2,4 1Regenerative Medicine Program, Ottawa Hospital Research Institute, 2Department of Cellular and Molecular Medicine, University of Ottawa, 3Department of Pharmacological Sciences, Stony Brook University, 4Department of Medicine, University of Ottawa JoVE 3324 Neuroscience
全山神经肌肉交界分析的 横向解剖阿布多米尼斯 肌肉 Lyndsay Murray1, Thomas H Gillingwater2, Rashmi Kothary1 1Regenerative Medicine Program, Ottawa Hospital Research Institute, 2Centre for Integrative Physiology, University of Edinburgh JoVE 51162 Neuroscience
丰富的少突胶质细胞培养和Myelinating产后小鼠组织联合培养的少突胶质细胞/神经元的推导 Ryan W. O'Meara1,2, Scott D. Ryan1, Holly Colognato3, Rashmi Kothary1,2,4 1Regenerative Medicine Program, Ottawa Hospital Research Institute, 2Department of Cellular and Molecular Medicine, University of Ottawa, 3Department of Pharmacological Sciences, Stony Brook University, 4Department of Medicine, University of Ottawa JoVE 3324 Neuroscience