Raymond Chuen-Chung Chang Laboratory of Neurodegenerative Disease, Li Ka Shing Faculty of Medicine University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region (HK SAR) Biography Publications Institution JoVE Articles Raymond Chuen-Chung Chang has not added a biography. If you are Raymond Chuen-Chung Chang and would like to personalize this page please email our Author Liaison for assistance. Publications The Beneficial Effects of Physical Exercise in the Brain and Related Pathophysiological Mechanisms in Neurodegenerative Diseases Laboratory Investigation; a Journal of Technical Methods and Pathology. Feb, 2019 | Pubmed ID: 30808929 Palmitate and Stearate Are Increased in the Plasma in a 6-OHDA Model of Parkinson's Disease Metabolites. Feb, 2019 | Pubmed ID: 30781729 Varenicline Reduces DNA Damage, Tau Mislocalization and Post Surgical Cognitive Impairment in Aged Mice Neuropharmacology. 12, 2018 | Pubmed ID: 30273594 Silica Nanoparticles Induce Neurodegeneration-like Changes in Behavior, Neuropathology, and Affect Synapse Through MAPK Activation Particle and Fibre Toxicology. Jul, 2018 | Pubmed ID: 29970116 Evidence of the Impact of Systemic Inflammation on Neuroinflammation from a Non-bacterial Endotoxin Animal Model Journal of Neuroinflammation. May, 2018 | Pubmed ID: 29776428 Bringing CLARITY to the Human Brain: Visualization of Lewy Pathology in Three Dimensions Neuropathology and Applied Neurobiology. 10, 2016 | Pubmed ID: 26526972 Editorial: Bioactive Small Molecules in Regulating Inflammation and Metabolic Disorder Current Topics in Medicinal Chemistry. 2016 | Pubmed ID: 26381415 PKR Deficiency Alters E. Coli-induced Sickness Behaviors but Does Not Exacerbate Neuroimmune Responses or Bacterial Load Journal of Neuroinflammation. Nov, 2015 | Pubmed ID: 26585788 Sickness: From the Focus on Cytokines, Prostaglandins, and Complement Factors to the Perspectives of Neurons Neuroscience and Biobehavioral Reviews. Oct, 2015 | Pubmed ID: 26363665 Investigating Degeneration of the Retina in Young and Aged Tau P301L Mice Life Sciences. Mar, 2015 | Pubmed ID: 25592136 Neuropathology of Cigarette Smoking Acta Neuropathologica. Jan, 2014 | Pubmed ID: 24240736 从小到大的分子: 我们如何防止和延缓与年龄有关的神经变性的研究进展? Current Pharmaceutical Design. 2012 | Pubmed ID: 22211681 枸杞多糖保护小鼠肝脏免受四氯化碳诱导的氧化应激和 Necroinflammation。 Journal of Ethnopharmacology. Jan, 2012 | Pubmed ID: 22138659 内质网应激诱导马头病理及形成一种恶性循环: 在阿尔茨海默病发病机制中的意义。 Journal of Alzheimer's Disease : JAD. Nov, 2011 | Pubmed ID: 22101233 神经变性的视网膜的阿尔茨海默病小鼠模型: 我们可以学什么从视网膜? Age (Dordrecht, Netherlands). May, 2011 | Pubmed ID: 21559868 从对神经变性中药新药在阿尔茨海默病和血管性痴呆。 Chinese Medicine. 2011 | Pubmed ID: 21513513 枸杞多糖减少神经元损伤、 血-视网膜屏障的破坏和氧化应激的视网膜缺血再灌注。 PloS One. 2011 | Pubmed ID: 21298100 轻型剥夺诱发抑郁样行为并抑制神经发生的昼夜 (长爪)。 Cell Transplantation. 2011 | Pubmed ID: 21054936 自噬和受到低分子量 β-淀粉样肽的神经元凋亡的时空关系。 Journal of Cellular and Molecular Medicine. Feb, 2011 | Pubmed ID: 20015199 含硫成分和一个 1 H-吡咯-2-羧酸酸衍生物从菠萝 [菠萝 (L.) 变异。] 水果。 Phytochemistry. Dec, 2010 | Pubmed ID: 20843530 作为阿尔茨海默病的药理作用目标线粒体钙的调节作用。 Ageing Research Reviews. Oct, 2010 | Pubmed ID: 20553970 肉桂原花青素形成的特定先进的终末和葡萄糖消费甲基乙二醛所致损害的有利影响。 Journal of Agricultural and Food Chemistry. Jun, 2010 | Pubmed ID: 20476737 抑郁症与阿尔茨海默病之间的假定存在神经退行性联系。 Progress in Neurobiology. Aug, 2010 | Pubmed ID: 20441786 晶状体蛋白的调控被参与神经保护作用的枸杞研究高眼压模型大鼠视网膜神经节细胞存活。 Journal of Cellular Biochemistry. May, 2010 | Pubmed ID: 20336662 枸杞子,枸杞子,对同型半胱氨酸致毒性的大鼠皮层神经元的果实多糖的神经保护作用。 Journal of Alzheimer's Disease : JAD. 2010 | Pubmed ID: 20157238 人类 FE65,阿尔茨海默病淀粉样前体蛋白,Sp1 的配体的转录调控。 Journal of Cellular Biochemistry. Mar, 2010 | Pubmed ID: 20091743 小胶质细胞和单核细胞趋化蛋白-1 在实验青光眼神经保护作用的形态学变化的调节作用。 Cellular & Molecular Immunology. Jan, 2010 | Pubmed ID: 20081877 万维网的绿茶多酚 (-)-茶素-3-没食子酸 (EGCG) 防止分化的 SH SY5Y 细胞从 6-羟基多巴胺所致的毒性。 Neuroscience Letters. Jan, 2010 | Pubmed ID: 20026175 抗衰老中药 — — 如何和为什么他们可在衰老有关的神经退行性疾病? Ageing Research Reviews. Jul, 2010 | Pubmed ID: 19833234 Pinostilbene 的保护作用,白藜芦醇甲基化衍生物,对 6-羟基致 SH SY5Y 细胞毒性作用。 The Journal of Nutritional Biochemistry. Jun, 2010 | Pubmed ID: 19443200 勘误: 调制小胶质细胞的枸杞对高眼压模型大鼠视网膜神经节细胞存活。 Journal of Ocular Biology, Diseases, and Informatics. Sep, 2009 | Pubmed ID: 20046845 Neuroimmune 反应对胶质细胞在中枢神经系统的调节作用: 对 Neuroinflammation 的干预治疗的意义。 Cellular & Molecular Immunology. Oct, 2009 | Pubmed ID: 19887044 救济款抑制可以调节人体神经变性吗? Expert Review of Neurotherapeutics. Oct, 2009 | Pubmed ID: 19831834 小胶质细胞的枸杞对高眼压模型大鼠视网膜神经节细胞存活的调制。 Journal of Ocular Biology, Diseases, and Informatics. Jun, 2009 | Pubmed ID: 19672466 阿尔茨海默病患者的钙时异常: 从机制到治疗的机会。 Progress in Neurobiology. Nov, 2009 | Pubmed ID: 19664678 枸杞多糖拮抗谷氨酸兴奋毒性大鼠脑皮质神经元。 Cellular and Molecular Neurobiology. Dec, 2009 | Pubmed ID: 19499323 低分子量 Abeta 诱导内质网的崩溃。 Molecular and Cellular Neurosciences. May, 2009 | Pubmed ID: 19386229 全反式维甲酸对人类 SH SY5Y 神经母细胞瘤体外模型中神经毒性研究与影响。 Neurotoxicology. Jan, 2009 | Pubmed ID: 19056420 膳食 Oxyresveratrol 可防止帕金森病模仿 6-羟基多巴胺神经毒性。 Free Radical Biology & Medicine. Oct, 2008 | Pubmed ID: 18675900 拮抗 β-淀粉样肽的抗衰老灵芝的毒性作用。 Brain Research. Jan, 2008 | Pubmed ID: 18083148 使用的抗衰老中药,枸杞子,对老化相关疾病。到目前为止我们知道些什么? Cellular and Molecular Neurobiology. Aug, 2008 | Pubmed ID: 17710531 对 β-淀粉样肽神经毒性的抗衰老医学枸杞影响的表征。 International Journal of Molecular Medicine. Aug, 2007 | Pubmed ID: 17611646 描述对 β-淀粉样肽神经毒性碱性提取物枸杞的神经保护作用影响。 Brain Research. Jul, 2007 | Pubmed ID: 17568570 夹竹桃新多糖保护神经元通过应力激酶信号转导通路。 Brain Research. Jun, 2007 | Pubmed ID: 17475226 枸杞子恩对保护青光眼高眼压模型视网膜神经节细胞的神经保护作用。 Experimental Neurology. Jan, 2007 | Pubmed ID: 17045262 分子信号蛋白翻译控制在神经退行性疾病中的意义。 Neuro-Signals. -2007, 2006 | Pubmed ID: 17496426 枸杞子对减少对内质网应激损伤的保护作用。 International Journal of Molecular Medicine. Jun, 2006 | Pubmed ID: 16685430 Β-淀粉样肽诱导神经元凋亡通过独立的未折叠的蛋白反应机制。 Apoptosis : an International Journal on Programmed Cell Death. May, 2006 | Pubmed ID: 16532272 新型神经保护作用的马鞭属植物的提取液。 Neuropharmacology. May, 2006 | Pubmed ID: 16406021 夏枯草对单核细胞/巨噬细胞的免疫调节作用。 International Journal of Molecular Medicine. Dec, 2005 | Pubmed ID: 16273294 抗衰老东方医学枸杞对 β-淀粉样肽神经毒性的神经保护作用。 Experimental Gerontology. Aug-Sep, 2005 | Pubmed ID: 16139464 EBERs 永生化鼻咽上皮细胞中的稳定表达赋予抗凋亡应力。 Molecular Carcinogenesis. Oct, 2005 | Pubmed ID: 16086371 夏枯草的免疫调节作用 International Journal of Molecular Medicine. Mar, 2005 | Pubmed ID: 15702244 夹竹桃和其神经保护作用的花多糖的表征。 International Journal of Molecular Medicine. Nov, 2004 | Pubmed ID: 15492866 钙/钙调蛋白激酶 II 调制提供部分对 β-淀粉样肽毒性的保护作用。 The European Journal of Neuroscience. Apr, 2004 | Pubmed ID: 15090032 减少从内质网钙释放只能提供部分对 β-淀粉样肽毒性的保护作用。 Journal of Neurochemistry. Dec, 2003 | Pubmed ID: 14713297 上游信号通路中 β-淀粉样肽神经毒性导致的双链 RNA 依赖性丝氨酸/苏氨酸蛋白激酶激活。 The Journal of Biological Chemistry. Dec, 2003 | Pubmed ID: 12975376 坏和 Bcl-2 调节是链接到线粒体介导的细胞凋亡神经元内质网应激的早期事件。 Brain Research. Molecular Brain Research. Dec, 2002 | Pubmed ID: 12531534 双链 RNA 依赖的蛋白激酶和磷酸化真核启动因子-2alpha 神经元变性的参与。 Journal of Neurochemistry. Dec, 2002 | Pubmed ID: 12437593 一种用于小鼠运动技能、情绪和认知重复评估的行为测试电池 Ran You1,2,3, Yan Liu3, Raymond Chuen-Chung Chang3 1Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, 2Nanjing Key Laboratory of Pediatrics, Nanjing Medical University, 3Laboratory of Neurodegenerative Disease, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region (HK SAR) JoVE 58973 Behavior 视网膜节的形态分析 Tin Fung Chan1, Kin Chiu1, Carmen Ka Ming Lok1, Wing Lau Ho1, Kwok-Fai So1,2,3, Raymond Chuen-Chung Chang1,2,3 1Laboratory of Neurodegenerative Diseases, Department of Anatomy, LKS Faculty of Medicine, The University of Hong Kong, 2Research Centre of Heart, Brain, Hormone and Healthy Aging, LKS Faculty of Medicine, The University of Hong Kong, 3State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong JoVE 3377 Neuroscience 上丘表面上应用氟金逆行标记视网膜神经节细胞 Kin Chiu1, Wui-Man Lau1, Sze-chun Yeung1, Raymond Chuen-Chung Chang1, Kwok-Fai So1 1The University of Hong Kong - HKU JoVE 819 Biology 玻璃体内注射眼部疾病模型建立 Kin Chiu1, Raymond Chuen-Chung Chang1, Kwok-Fai So1 1The University of Hong Kong - HKU JoVE 313 Biology 从特定的大脑区域的RNA或蛋白质提取大鼠脑微解剖 Kin Chiu1, Wui Man Lau1, Ho Tak Lau1, Kwok-Fai So1, Raymond Chuen-Chung Chang1 1Laboratory of Neurodegenerative Diseases, Department of Anatomy, LKS Faculty of Medicine, The University of Hong Kong - HKU JoVE 269 Biology
一种用于小鼠运动技能、情绪和认知重复评估的行为测试电池 Ran You1,2,3, Yan Liu3, Raymond Chuen-Chung Chang3 1Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, 2Nanjing Key Laboratory of Pediatrics, Nanjing Medical University, 3Laboratory of Neurodegenerative Disease, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region (HK SAR) JoVE 58973 Behavior
视网膜节的形态分析 Tin Fung Chan1, Kin Chiu1, Carmen Ka Ming Lok1, Wing Lau Ho1, Kwok-Fai So1,2,3, Raymond Chuen-Chung Chang1,2,3 1Laboratory of Neurodegenerative Diseases, Department of Anatomy, LKS Faculty of Medicine, The University of Hong Kong, 2Research Centre of Heart, Brain, Hormone and Healthy Aging, LKS Faculty of Medicine, The University of Hong Kong, 3State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong JoVE 3377 Neuroscience
上丘表面上应用氟金逆行标记视网膜神经节细胞 Kin Chiu1, Wui-Man Lau1, Sze-chun Yeung1, Raymond Chuen-Chung Chang1, Kwok-Fai So1 1The University of Hong Kong - HKU JoVE 819 Biology
玻璃体内注射眼部疾病模型建立 Kin Chiu1, Raymond Chuen-Chung Chang1, Kwok-Fai So1 1The University of Hong Kong - HKU JoVE 313 Biology
从特定的大脑区域的RNA或蛋白质提取大鼠脑微解剖 Kin Chiu1, Wui Man Lau1, Ho Tak Lau1, Kwok-Fai So1, Raymond Chuen-Chung Chang1 1Laboratory of Neurodegenerative Diseases, Department of Anatomy, LKS Faculty of Medicine, The University of Hong Kong - HKU JoVE 269 Biology