Rekha G. Panchal Division of Molecular and Translational Sciences US Army Medical Research Institute of Infectious Diseases Biography Publications Institution JoVE Articles Rekha G. Panchal has not added a biography. If you are Rekha G. Panchal and would like to personalize this page please email our Author Liaison for assistance. Publications Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names Viruses. Sep, 2014 | Pubmed ID: 25256396 Applications of In Vivo Imaging in the Evaluation of the Pathophysiology of Viral and Bacterial Infections and in Development of Countermeasures to BSL3/4 Pathogens Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Jul, 2014 | Pubmed ID: 25008802 Synthesis and Antibacterial Evaluation of New, Unsymmetrical Triaryl Bisamidine Compounds Bioorganic & Medicinal Chemistry Letters. Aug, 2014 | Pubmed ID: 24969013 A High-content Imaging Assay for the Quantification of the Burkholderia Pseudomallei Induced Multinucleated Giant Cell (MNGC) Phenotype in Murine Macrophages BMC Microbiology. 2014 | Pubmed ID: 24750902 Induced IL-10 Splice Altering Approach to Antiviral Drug Discovery Nucleic Acid Therapeutics. Jun, 2014 | Pubmed ID: 24655055 Protection Against Filovirus Diseases by a Novel Broad-spectrum Nucleoside Analogue BCX4430 Nature. Apr, 2014 | Pubmed ID: 24590073 Alveolar Macrophages Infected with Ames or Sterne Strain of Bacillus Anthracis Elicit Differential Molecular Expression Patterns PloS One. 2014 | Pubmed ID: 24516547 Potent and Broad-spectrum Antibacterial Activity of Indole-based Bisamidine Antibiotics: Synthesis and SAR of Novel Analogs of MBX 1066 and MBX 1090 Bioorganic & Medicinal Chemistry. Dec, 2013 | Pubmed ID: 24239389 Anthrax Toxin-induced Rupture of Artificial Lipid Bilayer Membranes The Journal of Chemical Physics. Aug, 2013 | Pubmed ID: 23947891 Characterization of the Burkholderia Thailandensis SOS Response by Using Whole-transcriptome Shotgun Sequencing Applied and Environmental Microbiology. Oct, 2013 | Pubmed ID: 23872555 A Systematic Screen of FDA-approved Drugs for Inhibitors of Biological Threat Agents PloS One. 2013 | Pubmed ID: 23577127 높은 콘텐츠 이미징 및 호스트 세포 경로 Yersinia Pestis 감염에 대 한 중요 한 프로브를 화학 유전학을 통합 PloS One. 2013 | Pubmed ID: 23383093 Bis-imidazolinylindoles Are Active Against Methicillin-resistant Staphylococcus Aureus and Multidrug-resistant Mycobacterium Tuberculosis The Journal of Antibiotics. Jan, 2013 | Pubmed ID: 23149517 Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of Ebola Virus and Marburg Virus Infections Viruses. Nov, 2012 | Pubmed ID: 23202506 High Content Image Based Analysis Identifies Cell Cycle Inhibitors As Regulators of Ebola Virus Infection Viruses. Oct, 2012 | Pubmed ID: 23202445 Shedding Light on Filovirus Infection with High-content Imaging Viruses. Aug, 2012 | Pubmed ID: 23012631 A Limited Structural Modification Results in a Significantly More Efficacious Diazachrysene-based Filovirus Inhibitor Viruses. Aug, 2012 | Pubmed ID: 23012625 Peptide Conjugated Phosphorodiamidate Morpholino Oligomers Increase Survival of Mice Challenged with Ames Bacillus Anthracis Nucleic Acid Therapeutics. Oct, 2012 | Pubmed ID: 22978365 High-throughput Screen Using a Single-cell Tyrosine Phosphatase Assay Reveals Biologically Active Inhibitors of Tyrosine Phosphatase CD45 Proceedings of the National Academy of Sciences of the United States of America. Aug, 2012 | Pubmed ID: 22891353 Identification of an Antioxidant Small-molecule with Broad-spectrum Antiviral Activity Antiviral Research. Jan, 2012 | Pubmed ID: 22027648 Identification of a Small-molecule Entry Inhibitor for Filoviruses Journal of Virology. Apr, 2011 | Pubmed ID: 21270170 A Chemotype That Inhibits Three Unrelated Pathogenic Targets: the Botulinum Neurotoxin Serotype A Light Chain, P. Falciparum Malaria, and the Ebola Filovirus Journal of Medicinal Chemistry. Mar, 2011 | Pubmed ID: 21265542 Development of High-content Imaging Assays for Lethal Viral Pathogens Journal of Biomolecular Screening. Aug, 2010 | Pubmed ID: 20639507 Comparative in Vitro Activity Profiles of Novel Bis-indole Antibacterials Against Gram-positive and Gram-negative Clinical Isolates Antimicrobial Agents and Chemotherapy. Sep, 2010 | Pubmed ID: 20625154 Efflux-mediated Bis-indole Resistance in Staphylococcus Aureus Reveals Differential Substrate Specificities for MepA and MepR Bioorganic & Medicinal Chemistry. Mar, 2010 | Pubmed ID: 20188576 Reduced Levels of Protein Tyrosine Phosphatase CD45 Protect Mice from the Lethal Effects of Ebola Virus Infection Cell Host & Microbe. Aug, 2009 | Pubmed ID: 19683682 Novel Broad-spectrum Bis-(imidazolinylindole) Derivatives with Potent Antibacterial Activities Against Antibiotic-resistant Strains Antimicrobial Agents and Chemotherapy. Oct, 2009 | Pubmed ID: 19635954 Reduced Expression of CD45 Protein-tyrosine Phosphatase Provides Protection Against Anthrax Pathogenesis The Journal of Biological Chemistry. May, 2009 | Pubmed ID: 19269962 Burkholderia Mallei TssM Encodes a Putative Deubiquitinase That is Secreted and Expressed Inside Infected RAW 264.7 Murine Macrophages Infection and Immunity. Apr, 2009 | Pubmed ID: 19168747 Sizing the Bacillus Anthracis PA63 Channel with Nonelectrolyte Poly(ethylene Glycols) Biophysical Journal. Aug, 2008 | Pubmed ID: 18645196 Filovirus-like Particles Produced in Insect Cells: Immunogenicity and Protection in Rodents The Journal of Infectious Diseases. Nov, 2007 | Pubmed ID: 17940979 A Refined Pharmacophore Identifies Potent 4-amino-7-chloroquinoline-based Inhibitors of the Botulinum Neurotoxin Serotype A Metalloprotease Journal of Medicinal Chemistry. May, 2007 | Pubmed ID: 17417831 Chemical Genetic Screening Identifies Critical Pathways in Anthrax Lethal Toxin-induced Pathogenesis Chemistry & Biology. Mar, 2007 | Pubmed ID: 17379140 Primary Cultures of Embryonic Chicken Neurons for Sensitive Cell-based Assay of Botulinum Neurotoxin: Implications for Therapeutic Discovery Journal of Biomolecular Screening. Apr, 2007 | Pubmed ID: 17332092 Inhibition of Metalloprotease Botulinum Serotype A from a Pseudo-peptide Binding Mode to a Small Molecule That is Active in Primary Neurons The Journal of Biological Chemistry. Feb, 2007 | Pubmed ID: 17092934 Anthrax Lethal Toxin Impairs Innate Immune Functions of Alveolar Macrophages and Facilitates Bacillus Anthracis Survival Infection and Immunity. Sep, 2006 | Pubmed ID: 16926394 Passive Immunotherapy of Bacillus Anthracis Pulmonary Infection in Mice with Antisera Produced by DNA Immunization Vaccine. Jul, 2006 | Pubmed ID: 16790303 Antisense Treatments for Biothreat Agents Current Opinion in Molecular Therapeutics. Apr, 2006 | Pubmed ID: 16610760 The Rapidly Advancing Field of Biodefense Benefits Many Other, Critical Public Health Concerns Discovery Medicine. Aug, 2005 | Pubmed ID: 20704875 Anthrax Biosensor, Protective Antigen Ion Channel Asymmetric Blockade The Journal of Biological Chemistry. Oct, 2005 | Pubmed ID: 16087661 Functional Reconstitution of Protein Ion Channels into Planar Polymerizable Phospholipid Membranes Nano Letters. Jun, 2005 | Pubmed ID: 15943465 An All-atom Model of the Pore-like Structure of Hexameric VP40 from Ebola: Structural Insights into the Monomer-hexamer Transition Journal of Structural Biology. Jul, 2005 | Pubmed ID: 15908231 Analysis of Ebola Virus and VLP Release Using an Immunocapture Assay Journal of Virological Methods. Jul, 2005 | Pubmed ID: 15893559 Dendritic Cells Endocytose Bacillus Anthracis Spores: Implications for Anthrax Pathogenesis Journal of Immunology (Baltimore, Md. : 1950). May, 2005 | Pubmed ID: 15843553 Purified Bacillus Anthracis Lethal Toxin Complex Formed in Vitro and During Infection Exhibits Functional and Biological Activity The Journal of Biological Chemistry. Mar, 2005 | Pubmed ID: 15644338 Conformational Sampling of the Botulinum Neurotoxin Serotype A Light Chain: Implications for Inhibitor Binding Bioorganic & Medicinal Chemistry. Jan, 2005 | Pubmed ID: 15598556 Identification of Small Molecule Inhibitors of Anthrax Lethal Factor Nature Structural & Molecular Biology. Jan, 2004 | Pubmed ID: 14718925 In Vivo Oligomerization and Raft Localization of Ebola Virus Protein VP40 During Vesicular Budding Proceedings of the National Academy of Sciences of the United States of America. Dec, 2003 | Pubmed ID: 14673115 Novel Small Molecule Inhibitors of Botulinum Neurotoxin A Metalloprotease Activity Biochemical and Biophysical Research Communications. Oct, 2003 | Pubmed ID: 14511652 Molecular Mechanisms of Filovirus Cellular Trafficking Microbes and Infection / Institut Pasteur. Jun, 2003 | Pubmed ID: 12787740 P2X7 Receptor Cell Surface Expression and Cytolytic Pore Formation Are Regulated by a Distal C-terminal Region The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12496266 The Rat Sodium Iodide Symporter Gene Permits More Effective Radioisotope Concentration Than the Human Sodium Iodide Symporter Gene in Human and Rodent Cancer Cells Cancer Gene Therapy. Jan, 2003 | Pubmed ID: 12489024 Fatty Acid Augmentation of the Cardiac Slowly Activating Delayed Rectifier Current (IKs) is Conferred by HminK FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2002 | Pubmed ID: 12206993 Pore Formation is Not Associated with Macroscopic Redistribution of P2X7 Receptors American Journal of Physiology. Cell Physiology. Jul, 2002 | Pubmed ID: 12055075 Release of Mitochondrial Ca2+ Via the Permeability Transition Activates Endoplasmic Reticulum Ca2+ Uptake FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2002 | Pubmed ID: 12039849 보툴리눔 신경독 억제제의 식별을 위해 높은 콘텐츠 이미징 분석 Krishna P. Kota1,6, Veronica Soloveva2,6,7, Laura M. Wanner3,6, Glenn Gomba4,6, Erkan Kiris3,5,6, Rekha G. Panchal6, Christopher D. Kane2,6,7, Sina Bavari6 1Perkin Elmer Inc., 2Henry M. Jackson Foundation, 3The Geneva Foundation, 4ORISE, 5Frederick National Laboratory for Cancer Research, 6Division of Molecular and Translational Sciences, US Army Medical Research Institute of Infectious Diseases, 7DoD Biotechnology High Performance Computing Software Applications Institute (BHSAI), Telemedicine and Advanced Technology Research Center (TATRC), US Army Medical Research and Materiel Command (USAMRMC) Neuroscience
보툴리눔 신경독 억제제의 식별을 위해 높은 콘텐츠 이미징 분석 Krishna P. Kota1,6, Veronica Soloveva2,6,7, Laura M. Wanner3,6, Glenn Gomba4,6, Erkan Kiris3,5,6, Rekha G. Panchal6, Christopher D. Kane2,6,7, Sina Bavari6 1Perkin Elmer Inc., 2Henry M. Jackson Foundation, 3The Geneva Foundation, 4ORISE, 5Frederick National Laboratory for Cancer Research, 6Division of Molecular and Translational Sciences, US Army Medical Research Institute of Infectious Diseases, 7DoD Biotechnology High Performance Computing Software Applications Institute (BHSAI), Telemedicine and Advanced Technology Research Center (TATRC), US Army Medical Research and Materiel Command (USAMRMC) Neuroscience
