Saeid Ghavami Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, Max Rady College of Medicine University of Manitoba Biography Publications Institution JoVE Articles Saeid Ghavami has not added a biography. If you are Saeid Ghavami and would like to personalize this page please email our Author Liaison for assistance. Publications Simultaneous Detection of Autophagy and Epithelial to Mesenchymal Transition in the Non-small Cell Lung Cancer Cells Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 29101677 Autophagy Activation in Asthma Airways Remodeling American Journal of Respiratory Cell and Molecular Biology. Nov, 2018 | Pubmed ID: 30383396 Association Between CASP3 Polymorphisms and Overall Cancer Risk: A Meta-analysis of Case-control Studies Journal of Cellular Biochemistry. Oct, 2018 | Pubmed ID: 30368918 Statins: a New Approach to Combat Temozolomide Chemoresistance in Glioblastoma Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research. Oct, 2018 | Pubmed ID: 30368483 Changes in Serum Level of Trace Elements in Pulmonary Tuberculosis Patients During Anti-tuberculosis Treatment Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS). Dec, 2018 | Pubmed ID: 30262275 LAPTM4B Gene Polymorphism Augments the Risk of Cancer: Evidence from an Updated Meta-analysis Journal of Cellular and Molecular Medicine. Sep, 2018 | Pubmed ID: 30255662 Association of Single Nucleotide Autophagy-related Protein 5 Gene Polymorphism Rs2245214 with Susceptibility to Non-small Cell Lung Cancer Journal of Cellular Biochemistry. Sep, 2018 | Pubmed ID: 30242869 Association Between MiR-34b/c Rs4938723 Polymorphism and Risk of Cancer: An Updated Meta-analysis of 27 Case-control Studies Journal of Cellular Biochemistry. Sep, 2018 | Pubmed ID: 30203457 Preparation and Characterization of Simvastatin Nanocapsules: Encapsulation of Hydrophobic Drugs in Calcium Alginate Methods in Molecular Biology (Clifton, N.J.). Aug, 2018 | Pubmed ID: 30159829 Toll-Like Receptor 4 As an Immune Receptor Against Mycobacterium Tuberculosis: A Systematic Review Laboratory Medicine. Aug, 2018 | Pubmed ID: 30124945 Association of PDCD6 Polymorphisms with the Risk of Cancer: Evidence from a Meta-analysis Oncotarget. May, 2018 | Pubmed ID: 29872511 A Comparison Between Cell, Protein and Peptide-Based Approaches for Selection of Nanobodies Against CD44 from a Synthetic Library Protein and Peptide Letters. 2018 | Pubmed ID: 29848261 Evaluation of 4-bp Insertion/deletion Polymorphism Within the 3'UTR of SGSM3 in Bladder Cancer Using Mismatch PCR-RFLP Method: A Preliminary Report Journal of Cellular Biochemistry. Aug, 2018 | Pubmed ID: 29693742 Autophagy Modulates Transforming Growth Factor Beta 1 Induced Epithelial to Mesenchymal Transition in Non-small Cell Lung Cancer Cells Biochimica Et Biophysica Acta. Molecular Cell Research. May, 2018 | Pubmed ID: 29481833 Association Between Single Nucleotide Polymorphisms in the PI3K/AKT/mTOR Pathway and Bladder Cancer Risk in a Sample of Iranian Population EXCLI Journal. 2018 | Pubmed ID: 29383014 Glioblastoma and Chemoresistance to Alkylating Agents: Involvement of Apoptosis, Autophagy, and Unfolded Protein Response Pharmacology & Therapeutics. Apr, 2018 | Pubmed ID: 29080702 Autophagy and the Unfolded Protein Response Promote Profibrotic Effects of TGF-β in Human Lung Fibroblasts American Journal of Physiology. Lung Cellular and Molecular Physiology. Mar, 2018 | Pubmed ID: 29074489 4-bp Insertion/deletion (rs3783553) Polymorphism Within the 3'UTR of IL1A Contributes to the Risk of Prostate Cancer in a Sample of Iranian Population Journal of Cellular Biochemistry. 03, 2018 | Pubmed ID: 29023981 Structure and Properties of Slow-resorbing Nanofibers Obtained by (co-axial) Electrospinning As Tissue Scaffolds in Regenerative Medicine PeerJ. 2017 | Pubmed ID: 29302386 Inflammasomes and Type 2 Diabetes: An Updated Systematic Review Immunology Letters. 12, 2017 | Pubmed ID: 29079203 Ral Signaling Pathway in Health and Cancer Cancer Medicine. Dec, 2017 | Pubmed ID: 29047224 Genetic Polymorphisms of HOTAIR Gene Are Associated with the Risk of Breast Cancer in a Sample of Southeast Iranian Population Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine. Oct, 2017 | Pubmed ID: 29022495 Dovitinib Enhances Temozolomide Efficacy in Glioblastoma Cells Molecular Oncology. 08, 2017 | Pubmed ID: 28500786 Toll Like Receptor 4 and Hepatocellular Carcinoma; A Systematic Review Life Sciences. Jun, 2017 | Pubmed ID: 28472619 Transdifferentiation and Reprogramming: Overview of the Processes, Their Similarities and Differences Biochimica Et Biophysica Acta. Molecular Cell Research. Jul, 2017 | Pubmed ID: 28460880 Association Between Polymorphisms in TP53 and MDM2 Genes and Susceptibility to Prostate Cancer Oncology Letters. Apr, 2017 | Pubmed ID: 28454424 Editorial: New Insights into a Classical Pathway: Key Roles of the Mevalonate Cascade in Different Diseases (Part II) Current Molecular Pharmacology. 2017 | Pubmed ID: 28440195 Human Gyrovirus-Apoptin Interferes with the Cell Cycle and Induces G2/M Arrest Prior to Apoptosis Archivum Immunologiae Et Therapiae Experimentalis. Dec, 2017 | Pubmed ID: 28386695 Corrigendum to "Epidermal Growth Factor Cytoplasmic Domain Affects ErbB Protein Degradation by the Lysosomal and Ubiquitin-Proteasome Pathway in Human Cancer Cells" [Neoplasia 14 (2012) 396-409] Neoplasia (New York, N.Y.). 04, 2017 | Pubmed ID: 28385276 New Frontiers in the Treatment of Colorectal Cancer: Autophagy and the Unfolded Protein Response As Promising Targets Autophagy. May, 2017 | Pubmed ID: 28358273 Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway Via Depletion of Isoprenoids in Tumor Cells Scientific Reports. 03, 2017 | Pubmed ID: 28344327 Microfluidic Approaches for Isolation, Detection, and Characterization of Extracellular Vesicles: Current Status and Future Directions Biosensors & Bioelectronics. May, 2017 | Pubmed ID: 28088752 Editorial (Thematic Issue: New Insights into a Classical Pathway: Key Roles of the Mevalonate Cascade in Different Diseases (Part I)) Current Molecular Pharmacology. 2017 | Pubmed ID: 26768962 Inhibition of Autophagy Inhibits the Conversion of Cardiac Fibroblasts to Cardiac Myofibroblasts Oncotarget. Nov, 2016 | Pubmed ID: 27705938 Photodynamic N-TiO Nanoparticle Treatment Induces Controlled ROS-mediated Autophagy and Terminal Differentiation of Leukemia Cells Scientific Reports. 10, 2016 | Pubmed ID: 27698385 Perturbation of Redox Balance After Thioredoxin Reductase Deficiency Interrupts Autophagy-lysosomal Degradation Pathway and Enhances Cell Death in Nutritionally Stressed SH-SY5Y Cells Free Radical Biology & Medicine. 12, 2016 | Pubmed ID: 27693380 Evaluation of the Pri-miR-34b/c Rs4938723 Polymorphism and Its Association with Breast Cancer Risk Biomedical Reports. Jul, 2016 | Pubmed ID: 27347415 Could Drugs Inhibiting the Mevalonate Pathway Also Target Cancer Stem Cells? Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 03, 2016 | Pubmed ID: 27155373 How Hepatitis C Virus Leads to Hepatocellular Carcinoma: A Network-Based Study Hepatitis Monthly. Feb, 2016 | Pubmed ID: 27148389 Chronic Expression of Ski Induces Apoptosis and Represses Autophagy in Cardiac Myofibroblasts Biochimica Et Biophysica Acta. Jun, 2016 | Pubmed ID: 27039037 Cancer Stem Cells, Cancer-initiating Cells and Methods for Their Detection Drug Discovery Today. 05, 2016 | Pubmed ID: 26976692 Inhibition of MiR301 Enhances Akt-mediated Cell Proliferation by Accumulation of PTEN in Nucleus and Its Effects on Cell-cycle Regulatory Proteins Oncotarget. Apr, 2016 | Pubmed ID: 26967567 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition) Autophagy. Jan, 2016 | Pubmed ID: 26799652 Cerebellar Expression of the Neurotrophin Receptor P75 in Naked-Ataxia Mutant Mouse International Journal of Molecular Sciences. Jan, 2016 | Pubmed ID: 26784182 Apoptosis, Autophagy and Unfolded Protein Response Pathways in Arbovirus Replication and Pathogenesis Expert Reviews in Molecular Medicine. Jan, 2016 | Pubmed ID: 26781343 Hepatitis B and C Virus-induced Hepatitis: Apoptosis, Autophagy, and Unfolded Protein Response World Journal of Gastroenterology. Dec, 2015 | Pubmed ID: 26715805 Effects of Ethanol on the Expression Level of Various BDNF MRNA Isoforms and Their Encoded Protein in the Hippocampus of Adult and Embryonic Rats International Journal of Molecular Sciences. Dec, 2015 | Pubmed ID: 26703578 The Role of the Ubiquitin Proteasome System in Cerebellar Development and Medulloblastoma Molecular Brain. Oct, 2015 | Pubmed ID: 26475605 The Expression Pattern of PFKFB3 Enzyme Distinguishes Between Induced-pluripotent Stem Cells and Cancer Stem Cells Oncotarget. Oct, 2015 | Pubmed ID: 26337471 Pre-administration of Turmeric Prevents Methotrexate-induced Liver Toxicity and Oxidative Stress BMC Complementary and Alternative Medicine. Jul, 2015 | Pubmed ID: 26199067 Association Between Programmed Cell Death 6 Interacting Protein Insertion/Deletion Polymorphism and the Risk of Breast Cancer in a Sample of Iranian Population Disease Markers. 2015 | Pubmed ID: 26063962 RAGE Mediates the Pro-Migratory Response of Extracellular S100A4 in Human Thyroid Cancer Cells Thyroid : Official Journal of the American Thyroid Association. May, 2015 | Pubmed ID: 25744544 Platinum (IV) Coiled Coil Nanotubes Selectively Kill Human Glioblastoma Cells Nanomedicine : Nanotechnology, Biology, and Medicine. May, 2015 | Pubmed ID: 25680541 Association Between Interleukin-1 Receptor Antagonist (IL1RN) Variable Number of Tandem Repeats (VNTR) Polymorphism and Pulmonary Tuberculosis Iranian Journal of Allergy, Asthma, and Immunology. Feb, 2015 | Pubmed ID: 25530139 Suppression of Influenza A Virus Replication in Human Lung Epithelial Cells by Noncytotoxic Concentrations Bafilomycin A1 American Journal of Physiology. Lung Cellular and Molecular Physiology. Feb, 2015 | Pubmed ID: 25361566 Perillyl Alcohol (Monoterpene Alcohol), Limonene The Enzymes. 2014 | Pubmed ID: 27102697 Cellular Commitment in the Developing Cerebellum Frontiers in Cellular Neuroscience. 2014 | Pubmed ID: 25628535 Association Between HTERT Polymorphisms and the Risk of Breast Cancer in a Sample of Southeast Iranian Population BMC Research Notes. Dec, 2014 | Pubmed ID: 25491902 Human-gyrovirus-Apoptin Triggers Mitochondrial Death Pathway--Nur77 is Required for Apoptosis Triggering Neoplasia (New York, N.Y.). Sep, 2014 | Pubmed ID: 25246270 Apoptins: Selective Anticancer Agents Trends in Molecular Medicine. Sep, 2014 | Pubmed ID: 25164066 Mechanisms of Therapeutic Resistance in Cancer (stem) Cells with Emphasis on Thyroid Cancer Cells Frontiers in Endocrinology. 2014 | Pubmed ID: 24723911 Airway Mesenchymal Cell Death by Mevalonate Cascade Inhibition: Integration of Autophagy, Unfolded Protein Response and Apoptosis Focusing on Bcl2 Family Proteins Biochimica Et Biophysica Acta. Jul, 2014 | Pubmed ID: 24637330 Targeting the Mevalonate Cascade As a New Therapeutic Approach in Heart Disease, Cancer and Pulmonary Disease Pharmacology & Therapeutics. Jul, 2014 | Pubmed ID: 24582968 Reprogramming and Carcinogenesis--parallels and Distinctions International Review of Cell and Molecular Biology. 2014 | Pubmed ID: 24411172 Autophagy and Apoptosis Dysfunction in Neurodegenerative Disorders Progress in Neurobiology. Jan, 2014 | Pubmed ID: 24211851 The Ski-Zeb2-Meox2 Pathway Provides a Novel Mechanism for Regulation of the Cardiac Myofibroblast Phenotype Journal of Cell Science. Jan, 2014 | Pubmed ID: 24155330 Association of Adiponectin Rs1501299 and Rs266729 Gene Polymorphisms With Nonalcoholic Fatty Liver Disease Hepatitis Monthly. May, 2013 | Pubmed ID: 23922565 Different Faces of Hepatocellular Carcinoma As a Health Threat in 21st Century Hepatitis Monthly. Feb, 2013 | Pubmed ID: 23613688 Asthma and Influenza Virus Infection:focusing on Cell Death and Stress Pathways in Influenza Virus Replication Iranian Journal of Allergy, Asthma, and Immunology. Mar, 2013 | Pubmed ID: 23454774 Functional Polymorphisms of FAS and FASL Gene and Risk of Breast Cancer - Pilot Study of 134 Cases PloS One. 2013 | Pubmed ID: 23326385 Novel Non-canonical TGF-β Signaling Networks: Emerging Roles in Airway Smooth Muscle Phenotype and Function Pulmonary Pharmacology & Therapeutics. Feb, 2013 | Pubmed ID: 22874922 Motility, Survival, and Proliferation Comprehensive Physiology. Jan, 2012 | Pubmed ID: 23728975 Autophagy Regulates Trans Fatty Acid-mediated Apoptosis in Primary Cardiac Myofibroblasts Biochimica Et Biophysica Acta. Dec, 2012 | Pubmed ID: 23026405 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy Autophagy. Apr, 2012 | Pubmed ID: 22966490 Epidermal Growth Factor Cytoplasmic Domain Affects ErbB Protein Degradation by the Lysosomal and Ubiquitin-proteasome Pathway in Human Cancer Cells Neoplasia (New York, N.Y.). May, 2012 | Pubmed ID: 22745586 Geranylgeranyl Transferase 1 Modulates Autophagy and Apoptosis in Human Airway Smooth Muscle American Journal of Physiology. Lung Cellular and Molecular Physiology. Feb, 2012 | Pubmed ID: 22160308 Hepatocellular Recurrence After Orthotopic Liver Transplantation: Is Combination of α-fetoprotein and Glypican-3 a Reliable Marker?: Hepatocellular Recurrence After Orthotopic Liver Trasplantation Hepatitis Monthly. Mar, 2011 | Pubmed ID: 22087135 Simvastatin Inhibits TGFβ1-induced Fibronectin in Human Airway Fibroblasts Respiratory Research. Aug, 2011 | Pubmed ID: 21864337 Mevalonate Cascade Regulation of Airway Mesenchymal Cell Autophagy and Apoptosis: a Dual Role for P53 PloS One. Jan, 2011 | Pubmed ID: 21304979 Antifibrotic Properties of C-Ski and Its Regulation of Cardiac Myofibroblast Phenotype and Contractility American Journal of Physiology. Cell Physiology. Jan, 2011 | Pubmed ID: 20943957 The Mevalonate Cascade As a Target to Suppress Extracellular Matrix Synthesis by Human Airway Smooth Muscle American Journal of Respiratory Cell and Molecular Biology. Mar, 2011 | Pubmed ID: 20463291 The Role of Fas-FasL Signaling Pathway in Induction of Apoptosis in Patients with Sulfur Mustard-Induced Chronic Bronchiolitis Journal of Toxicology. 2010 | Pubmed ID: 21317984 Beta-Dystroglycan Binds Caveolin-1 in Smooth Muscle: a Functional Role in Caveolae Distribution and Ca2+ Release Journal of Cell Science. Sep, 2010 | Pubmed ID: 20736308 Statin-triggered Cell Death in Primary Human Lung Mesenchymal Cells Involves P53-PUMA and Release of Smac and Omi but Not Cytochrome C Biochimica Et Biophysica Acta. Apr, 2010 | Pubmed ID: 20045437 S100A8/A9 Induces Autophagy and Apoptosis Via ROS-mediated Cross-talk Between Mitochondria and Lysosomes That Involves BNIP3 Cell Research. Mar, 2010 | Pubmed ID: 19935772 S100A8/A9: a Mediator of Severe Asthma Pathogenesis and Morbidity? Canadian Journal of Physiology and Pharmacology. Oct, 2009 | Pubmed ID: 19898558 S100A8/A9: a Janus-faced Molecule in Cancer Therapy and Tumorgenesis European Journal of Pharmacology. Dec, 2009 | Pubmed ID: 19835859 Brevinin-2R(1) Semi-selectively Kills Cancer Cells by a Distinct Mechanism, Which Involves the Lysosomal-mitochondrial Death Pathway Journal of Cellular and Molecular Medicine. Jun, 2008 | Pubmed ID: 18494941 S100A8/A9 at Low Concentration Promotes Tumor Cell Growth Via RAGE Ligation and MAP Kinase-dependent Pathway Journal of Leukocyte Biology. Jun, 2008 | Pubmed ID: 18339893 Autoimmunity and Apoptosis--therapeutic Implications Current Medicinal Chemistry. 2007 | Pubmed ID: 18220747 Cancer-specific Toxicity of Apoptin is Independent of Death Receptors but Involves the Loss of Mitochondrial Membrane Potential and the Release of Mitochondrial Cell-death Mediators by a Nur77-dependent Pathway Journal of Cell Science. Oct, 2005 | Pubmed ID: 16179607 छोटे GTPase Prenylation और GTP झिल्ली अंश और GTPase से जुड़े Immunosorbent परख का उपयोग बाध्यकारी का पता लगाने Javad Alizadeh1,2, Shahla Shojaei1,2,3, Simone da Silva Rosa1, Adel Rezaei Moghadam1,2, Amir A. Zeki4, Mohammad Hashemi5, Marek J. Los6,7,8, Joseph W. Gordon1,9, Saeid Ghavami1,2,10 1Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, 2Biology of Breathing Theme, Children Hospital Research Institute of Manitoba, University of Manitoba, 3Department of Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, 4Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, Center for Comparative Respiratory Biology and Medicine, 5Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, 6Department of Molecular Biology, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia, 7Centre de biophysique moléculaire - UPR 4301, Centre national de la recherche scientifique (CNRS) CS80054, 8LinkoCare Life Sciences AB, 9College of Nursing and Children's Hospital Research Institute of Manitoba, Rady Faculty of Health Sciences, University of Manitoba, 10Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences JoVE 57646 Biochemistry
छोटे GTPase Prenylation और GTP झिल्ली अंश और GTPase से जुड़े Immunosorbent परख का उपयोग बाध्यकारी का पता लगाने Javad Alizadeh1,2, Shahla Shojaei1,2,3, Simone da Silva Rosa1, Adel Rezaei Moghadam1,2, Amir A. Zeki4, Mohammad Hashemi5, Marek J. Los6,7,8, Joseph W. Gordon1,9, Saeid Ghavami1,2,10 1Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, 2Biology of Breathing Theme, Children Hospital Research Institute of Manitoba, University of Manitoba, 3Department of Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, 4Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, Center for Comparative Respiratory Biology and Medicine, 5Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, 6Department of Molecular Biology, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia, 7Centre de biophysique moléculaire - UPR 4301, Centre national de la recherche scientifique (CNRS) CS80054, 8LinkoCare Life Sciences AB, 9College of Nursing and Children's Hospital Research Institute of Manitoba, Rady Faculty of Health Sciences, University of Manitoba, 10Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences JoVE 57646 Biochemistry