Sandra Fischer Department of Laboratory Medicine and Pathobiology University of Toronto Biography Publications Institution JoVE Articles Sandra Fischer has not added a biography. If you are Sandra Fischer and would like to personalize this page please email our Author Liaison for assistance. Publications Radiological Tumor Response and Histopathological Correlation of Hepatocellular Carcinoma Treated with Stereotactic Body Radiation Therapy As a Bridge to Liver Transplantation Abdominal Radiology (New York). Oct, 2020 | Pubmed ID: 33074426 Clinical and Genomic Characterisation of Mismatch Repair Deficient Pancreatic Adenocarcinoma Gut. Sep, 2020 | Pubmed ID: 32933947 A Preclinical Trial and Molecularly Annotated Patient Cohort Identify Predictive Biomarkers in Homologous Recombination-deficient Pancreatic Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2020 | Pubmed ID: 32816949 Can Machine Learning Radiomics Provide Pre-operative Differentiation of Combined Hepatocellular Cholangiocarcinoma from Hepatocellular Carcinoma and Cholangiocarcinoma to Inform Optimal Treatment Planning? European Radiology. Aug, 2020 | Pubmed ID: 32749585 Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome Cancer Research. 07, 2020 | Pubmed ID: 32376602 Nanoparticle Uptake in a Spontaneous and Immunocompetent Woodchuck Liver Cancer Model ACS Nano. 04, 2020 | Pubmed ID: 32255624 GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2020 | Pubmed ID: 32156747 Obstructive Sleep Apnea and Non-alcoholic Fatty Liver Disease in Obese Patients Undergoing Bariatric Surgery Obesity Surgery. Jul, 2020 | Pubmed ID: 32124219 Author Correction: Transcription Phenotypes of Pancreatic Cancer Are Driven by Genomic Events During Tumor Evolution Nature Genetics. Apr, 2020 | Pubmed ID: 32051610 A Four-Chemokine Signature Is Associated with a T-cell-Inflamed Phenotype in Primary and Metastatic Pancreatic Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2020 | Pubmed ID: 31964786 Transcription Phenotypes of Pancreatic Cancer Are Driven by Genomic Events During Tumor Evolution Nature Genetics. 02, 2020 | Pubmed ID: 31932696 A Clinical-radiomic Model for Improved Prognostication of Surgical Candidates with Colorectal Liver Metastases Journal of Surgical Oncology. Dec, 2019 | Pubmed ID: 31797378 Cancer-related Gene Expression is Associated with Disease Severity and Modifiable Lifestyle Factors in Non-alcoholic Fatty Liver Disease Nutrition (Burbank, Los Angeles County, Calif.). 06, 2019 | Pubmed ID: 30870804 Effect of Portal Vein Embolization on Treatment Plan Prior to Major Hepatectomy for Hepatocellular Carcinoma HPB : the Official Journal of the International Hepato Pancreato Biliary Association. 08, 2019 | Pubmed ID: 30797726 Imaging Post-stereotactic Body Radiation Therapy Responses for Hepatocellular Carcinoma: Typical Imaging Patterns and Pitfalls Abdominal Radiology (New York). 05, 2019 | Pubmed ID: 30710166 Integration of Genomic and Transcriptional Features in Pancreatic Cancer Reveals Increased Cell Cycle Progression in Metastases Cancer Cell. 02, 2019 | Pubmed ID: 30686769 Gross and Microscopic Changes of Liver Neoplasms and Background Hepatic Structures Following Neoadjuvant Therapy Journal of Clinical Pathology. Feb, 2019 | Pubmed ID: 30670563 Whole Genomes Define Concordance of Matched Primary, Xenograft, and Organoid Models of Pancreas Cancer PLoS Computational Biology. 01, 2019 | Pubmed ID: 30629588 The Development and Validation of Magnetic Resonance Elastography for Fibrosis Staging in Primary Sclerosing Cholangitis European Radiology. Feb, 2019 | Pubmed ID: 30051141 Altered Hepatic Genes Related to Retinol Metabolism and Plasma Retinol in Patients with Non-alcoholic Fatty Liver Disease PloS One. 2018 | Pubmed ID: 30379862 Markers of Activated Inflammatory Cells Are Associated with Disease Severity and Intestinal Microbiota In adults with Non‑alcoholic Fatty Liver Disease International Journal of Molecular Medicine. Oct, 2018 | Pubmed ID: 30085339 In Nonalcoholic Fatty Liver Disease, Roux-en-Y Gastric Bypass Improves Liver Histology While Persistent Disease is Associated with Lower Improvements in Waist Circumference and Glycemic Control Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery. Sep, 2018 | Pubmed ID: 30049593 Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer Cancer Discovery. 09, 2018 | Pubmed ID: 29853643 Utility of Shear-wave Elastography to Differentiate Low from Advanced Degrees of Liver Fibrosis in Patients with Hepatitis C Virus Infection of Native and Transplant Livers Journal of Clinical Ultrasound : JCU. Jun, 2018 | Pubmed ID: 29508406 MRI Features of Combined Hepatocellular- Cholangiocarcinoma Versus Mass Forming Intrahepatic Cholangiocarcinoma Cancer Imaging : the Official Publication of the International Cancer Imaging Society. Feb, 2018 | Pubmed ID: 29486800 Nonalcoholic Fatty Liver Disease is Associated with Dysbiosis Independent of Body Mass Index and Insulin Resistance Scientific Reports. 01, 2018 | Pubmed ID: 29362454 Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 03, 2018 | Pubmed ID: 29288237 Prediction of the Histopathologic Findings of Intrahepatic Cholangiocarcinoma: Qualitative and Quantitative Assessment of Diffusion-weighted Imaging European Radiology. May, 2018 | Pubmed ID: 29234913 Non-alcoholic Fatty Liver Disease in Morbidly Obese Individuals Undergoing Bariatric Surgery: Prevalence and Effect of the Pre-Bariatric Very Low Calorie Diet Obesity Surgery. 04, 2018 | Pubmed ID: 29098545 Can Negligible Hepatic Steatosis Determined by Magnetic Resonance Imaging-proton Density Fat Fraction Obviate the Need for Liver Biopsy in Potential Liver Donors? Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 04, 2018 | Pubmed ID: 29080242 Systematic Integrative Analysis of Gene Expression Identifies HNF4A As the Central Gene in Pathogenesis of Non-alcoholic Steatohepatitis PloS One. 2017 | Pubmed ID: 29216278 Prospective Comparison of Gadoxetic Acid-enhanced Liver MRI and Contrast-enhanced CT with Histopathological Correlation for Preoperative Detection of Colorectal Liver Metastases Following Chemotherapy and Potential Impact on Surgical Plan HPB : the Official Journal of the International Hepato Pancreato Biliary Association. 11, 2017 | Pubmed ID: 28760631 Stereotactic Body Radiotherapy Vs. TACE or RFA As a Bridge to Transplant in Patients with Hepatocellular Carcinoma. An Intention-to-treat Analysis Journal of Hepatology. 07, 2017 | Pubmed ID: 28257902 Primary Perivascular Epithelioid Cell Tumors of the Liver: CT/MRI Findings and Clinical Outcomes Abdominal Radiology (New York). 06, 2017 | Pubmed ID: 28246920 Treatment with Optifast Reduces Hepatic Steatosis and Increases Candidacy Rates for Living Donor Liver Transplantation Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 09, 2016 | Pubmed ID: 27314458 Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease PloS One. 2016 | Pubmed ID: 27203081 Diffusion-weighted and Hepatobiliary Phase Gadoxetic Acid-enhanced Quantitative MR Imaging for Identification of Complete Pathologic Response in Colorectal Liver Metastases After Preoperative Chemotherapy Abdominal Radiology (New York). Feb, 2016 | Pubmed ID: 26867904 Liver Failure After Abdominal Irradiation: Identifying the Right Suspects Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jul, 2014 | Pubmed ID: 25071139 Impact of Viral Hepatitis on Outcomes After Liver Resection for Hepatocellular Carcinoma: Results from a North American Center Annals of Surgical Oncology. Aug, 2014 | Pubmed ID: 24806113 Frequency and Significance of IgG4 Immunohistochemical Staining in Liver Explants from Patients with Primary Sclerosing Cholangitis International Journal of Experimental Pathology. Jun, 2014 | Pubmed ID: 24750423 Identification of Driver Genes in Hepatocellular Carcinoma by Exome Sequencing Hepatology (Baltimore, Md.). Nov, 2013 | Pubmed ID: 23728943 Blood Oxygen Level-dependent Liver MRI: Can It Predict Microvascular Invasion in HCC? Journal of Magnetic Resonance Imaging : JMRI. Mar, 2013 | Pubmed ID: 23125092 Patients with Autoimmune Hepatitis Who Have Antimitochondrial Antibodies Need Long-term Follow-up to Detect Late Development of Primary Biliary Cirrhosis Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Jun, 2012 | Pubmed ID: 22366178 IgG4-related Sclerosing Disease: Autoimmune Pancreatitis and Extrapancreatic Manifestations Radiographics : a Review Publication of the Radiological Society of North America, Inc. Sep-Oct, 2011 | Pubmed ID: 21918050 Association of Hepatic Hemangiomatosis with Giant Cavernous Hemangioma in the Adult Population: Prevalence, Imaging Appearance, and Relevance AJR. American Journal of Roentgenology. Apr, 2011 | Pubmed ID: 21427329 Non-viral-related Pathologic Findings in Liver Needle Biopsy Specimens from Patients with Chronic Viral Hepatitis American Journal of Clinical Pathology. Jan, 2010 | Pubmed ID: 20023268 The Use of Cytokeratin 19 (CK19) Immunohistochemistry in Lesions of the Pancreas, Gastrointestinal Tract, and Liver Applied Immunohistochemistry & Molecular Morphology : AIMM. Jan, 2010 | Pubmed ID: 19956064 Cell-type Specific Gene Expression Signature in Liver Underlies Response to Interferon Therapy in Chronic Hepatitis C Infection Gastroenterology. Mar, 2010 | Pubmed ID: 19900446 Intrahepatic Bile Duct Dilatation Due to Liver Metastases from Colorectal Carcinoma AJR. American Journal of Roentgenology. Sep, 2009 | Pubmed ID: 19696289 Tumor-derived Ikaros 6 Acetylates the Bcl-XL Promoter to Up-regulate a Survival Signal in Pituitary Cells Molecular Endocrinology (Baltimore, Md.). Nov, 2006 | Pubmed ID: 16873443 An Essential Role for the Hematopoietic Transcription Factor Ikaros in Hypothalamic-pituitary-mediated Somatic Growth Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006 | Pubmed ID: 16467156 Handheld Computing in Medicine Journal of the American Medical Informatics Association : JAMIA. Mar-Apr, 2003 | Pubmed ID: 12595403 Surgical Procedure Logging with Use of a Hand-held Computer Canadian Journal of Surgery. Journal Canadien De Chirurgie. Oct, 2002 | Pubmed ID: 12387537 Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation Xu-Chun Chen*1, Manmeet Sekhon*1,2, Xue-Zhong Ma*1, Justin Manuel1, Sai Chung1,2, Eddie He1, Agata Bartczak1, Sandra Fischer3, Cornelia Thoeni3, Graziano Oldani1, Catia T. Perciani1, Sonya MacParland1,2,3, Ian McGilvray1 1Multi-Organ Transplant Program, University Health Network, 2Department of Immunology, University of Toronto, 3Department of Laboratory Medicine and Pathobiology, University of Toronto JoVE 60628 Medicine
Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation Xu-Chun Chen*1, Manmeet Sekhon*1,2, Xue-Zhong Ma*1, Justin Manuel1, Sai Chung1,2, Eddie He1, Agata Bartczak1, Sandra Fischer3, Cornelia Thoeni3, Graziano Oldani1, Catia T. Perciani1, Sonya MacParland1,2,3, Ian McGilvray1 1Multi-Organ Transplant Program, University Health Network, 2Department of Immunology, University of Toronto, 3Department of Laboratory Medicine and Pathobiology, University of Toronto JoVE 60628 Medicine
