Sang-Jun Ha

Publications

• Cell Type Preference of a Novel Human Derived Cell-Permeable Peptide DNP2 and TAT in Murine Splenic Immune Cells
  PloS One. 2016  |   Pubmed ID: 27186978
• Cisplatin Induces Tolerogenic Dendritic Cells in Response to TLR Agonists Via the Abundant Production of IL-10, Thereby Promoting Th2- and Tr1-biased T-cell Immunity
  Oncotarget. May, 2016  |   Pubmed ID: 27172902
• Effect of IL-4 on the Development and Function of Memory-like CD8 T Cells in the Peripheral Lymphoid Tissues
  Immune Network. Apr, 2016  |   Pubmed ID: 27162529
• Generation of Tolerogenic Dendritic Cells and Their Therapeutic Applications
  Immune Network. Feb, 2016  |   Pubmed ID: 26937232
• Altered Biological Potential and Radioresponse of Murine Tumors in Different Microenvironments
  Cancer Research and Treatment : Official Journal of Korean Cancer Association. Apr, 2016  |   Pubmed ID: 26323643
• Correction: PD-1 Upregulated on Regulatory T Cells During Chronic Virus Infection Enhances the Suppression of CD8+ T Cell Immune Response Via the Interaction with PD-L1 Expressed on CD8+ T Cells
  Journal of Immunology (Baltimore, Md. : 1950). Dec, 2015  |   Pubmed ID: 26637664
• A Small Molecule Inhibitor for ATPase Activity of Hsp70 and Hsc70 Enhances the Immune Response to Protein Antigens
  Scientific Reports. 2015  |   Pubmed ID: 26631605
• AMIGO2, a Novel Membrane Anchor of PDK1, Controls Cell Survival and Angiogenesis Via Akt Activation
  The Journal of Cell Biology. Nov, 2015  |   Pubmed ID: 26553931
• IL-4 Induced Innate CD8+ T Cells Control Persistent Viral Infection
  PLoS Pathogens. Oct, 2015  |   Pubmed ID: 26452143
• PD-1: Dual Guard for Immunopathology
  Oncotarget. Sep, 2015  |   Pubmed ID: 26318040
• PD-1 Upregulated on Regulatory T Cells During Chronic Virus Infection Enhances the Suppression of CD8+ T Cell Immune Response Via the Interaction with PD-L1 Expressed on CD8+ T Cells
  Journal of Immunology (Baltimore, Md. : 1950). Jun, 2015  |   Pubmed ID: 25934860
• Identification of a Subnuclear Body Involved in Sequence-specific Cytokine RNA Processing
  Nature Communications. 2015  |   Pubmed ID: 25557830
• Diagnostic Performance of a Cytokine and IFN-γ-induced Chemokine MRNA Assay After Mycobacterium Tuberculosis-specific Antigen Stimulation in Whole Blood from Infected Individuals
  The Journal of Molecular Diagnostics : JMD. Jan, 2015  |   Pubmed ID: 25528189
• Discrimination Between Active and Latent Tuberculosis Based on Ratio of Antigen-specific to Mitogen-induced IP-10 Production
  Journal of Clinical Microbiology. Feb, 2015  |   Pubmed ID: 25428147
• Peptidylarginine Deiminase Inhibition Impairs Toll-like Receptor Agonist-induced Functional Maturation of Dendritic Cells, Resulting in the Loss of T Cell-proliferative Capacity: a Partial Mechanism with Therapeutic Potential in Inflammatory Settings
  Journal of Leukocyte Biology. Feb, 2015  |   Pubmed ID: 25420918
• Inhibition of IL-17A Suppresses Enhanced-tumor Growth in Low Dose Pre-irradiated Tumor Beds
  PloS One. 2014  |   Pubmed ID: 25181290
• Enhancing T Cell Immune Responses by B Cell-based Therapeutic Vaccine Against Chronic Virus Infection
  Immune Network. Aug, 2014  |   Pubmed ID: 25177253
• Direct Endothelial Junction Restoration Results in Significant Tumor Vascular Normalization and Metastasis Inhibition in Mice
  Oncotarget. May, 2014  |   Pubmed ID: 24811731
• Regulatory T Cells-an Important Target for Cancer Immunotherapy
  Nature Reviews. Clinical Oncology. Jun, 2014  |   Pubmed ID: 24781417
• Highly Efficient Gene Knockout in Mice and Zebrafish with RNA-guided Endonucleases
  Genome Research. Jan, 2014  |   Pubmed ID: 24253447
• Differentiation of Antigen-specific T Cells with Limited Functional Capacity During Mycobacterium Tuberculosis Infection
  Infection and Immunity. Jan, 2014  |   Pubmed ID: 24126533
• Negative Regulation of Type I IFN Expression by OASL1 Permits Chronic Viral Infection and CD8⁺ T-cell Exhaustion
  PLoS Pathogens. 2013  |   Pubmed ID: 23874199
• Egr2 Induced During DC Development Acts As an Intrinsic Negative Regulator of DC Immunogenicity
  European Journal of Immunology. Sep, 2013  |   Pubmed ID: 23716134
• The Impact of Cigarette Smoking on the Frequency of and Qualitative Differences in KRAS Mutations in Korean Patients with Lung Adenocarcinoma
  Yonsei Medical Journal. Jul, 2013  |   Pubmed ID: 23709419
• PD-L1 Blockade Synergizes with IL-2 Therapy in Reinvigorating Exhausted T Cells
  The Journal of Clinical Investigation. Jun, 2013  |   Pubmed ID: 23676462
• Interleukin-21 is a Critical Cytokine for the Generation of Virus-specific Long-lived Plasma Cells
  Journal of Virology. Jul, 2013  |   Pubmed ID: 23637417
• Recruitment of Monocytes/macrophages in Different Tumor Microenvironments
  Biochimica Et Biophysica Acta. Apr, 2013  |   Pubmed ID: 23287570
• A Phase I Trial of Gefitinib and Nimotuzumab in Patients with Advanced Non-small Cell Lung Cancer (NSCLC)
  Lung Cancer (Amsterdam, Netherlands). Mar, 2013  |   Pubmed ID: 23261229
• Fibroblast Growth Factor Receptor 1 Gene Amplification is Associated with Poor Survival and Cigarette Smoking Dosage in Patients with Resected Squamous Cell Lung Cancer
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Feb, 2013  |   Pubmed ID: 23182986
• Tumor-infiltrating Regulatory T Cells Delineated by Upregulation of PD-1 and Inhibitory Receptors
  Cellular Immunology. Jul-Aug, 2012  |   Pubmed ID: 23121978
• Activation of IL-6R/JAK1/STAT3 Signaling Induces De Novo Resistance to Irreversible EGFR Inhibitors in Non-small Cell Lung Cancer with T790M Resistance Mutation
  Molecular Cancer Therapeutics. Oct, 2012  |   Pubmed ID: 22891040
• Mind Bomb-1 in Dendritic Cells is Specifically Required for Notch-mediated T Helper Type 2 Differentiation
  PloS One. 2012  |   Pubmed ID: 22558446
• High EGFR Gene Copy Number and Skin Rash As Predictive Markers for EGFR Tyrosine Kinase Inhibitors in Patients with Advanced Squamous Cell Lung Carcinoma
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2012  |   Pubmed ID: 22271877
• Distinct Clinical Features and Outcomes in Never-smokers with Nonsmall Cell Lung Cancer Who Harbor EGFR or KRAS Mutations or ALK Rearrangement
  Cancer. Feb, 2012  |   Pubmed ID: 21720997
• Antigen-specific CD4 T-cell Help Rescues Exhausted CD8 T Cells During Chronic Viral Infection
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011  |   Pubmed ID: 22160724
• Co-immunization of Plasmid DNA Encoding IL-12 and IL-18 with Bacillus Calmette-Guérin Vaccine Against Progressive Tuberculosis
  Yonsei Medical Journal. Nov, 2011  |   Pubmed ID: 22028167
• Chronic Virus Infection Enforces Demethylation of the Locus That Encodes PD-1 in Antigen-specific CD8(+) T Cells
  Immunity. Sep, 2011  |   Pubmed ID: 21943489
• 4-1BB Signaling Synergizes with Programmed Death Ligand 1 Blockade to Augment CD8 T Cell Responses During Chronic Viral Infection
  Journal of Immunology (Baltimore, Md. : 1950). Aug, 2011  |   Pubmed ID: 21742975
• Mechanism of T Cell Exhaustion in a Chronic Environment
  BMB Reports. Apr, 2011  |   Pubmed ID: 21524346
• Lung Cancer in Never Smokers: Change of a Mindset in the Molecular Era
  Lung Cancer (Amsterdam, Netherlands). Apr, 2011  |   Pubmed ID: 21272954
• Cooperation of Tim-3 and PD-1 in CD8 T-cell Exhaustion During Chronic Viral Infection
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010  |   Pubmed ID: 20679213
• PD-L1 Has Distinct Functions in Hematopoietic and Nonhematopoietic Cells in Regulating T Cell Responses During Chronic Infection in Mice
  The Journal of Clinical Investigation. Jul, 2010  |   Pubmed ID: 20551512
• Visualizing Antigen-specific and Infected Cells in Situ Predicts Outcomes in Early Viral Infection
  Science (New York, N.Y.). Mar, 2009  |   Pubmed ID: 19325114
• Impact of Epitope Escape on PD-1 Expression and CD8 T-cell Exhaustion During Chronic Infection
  Journal of Virology. May, 2009  |   Pubmed ID: 19211743
• IL-10 and PD-L1 Operate Through Distinct Pathways to Suppress T-cell Activity During Persistent Viral Infection
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008  |   Pubmed ID: 19075244
• Manipulating Both the Inhibitory and Stimulatory Immune System Towards the Success of Therapeutic Vaccination Against Chronic Viral Infections
  Immunological Reviews. Jun, 2008  |   Pubmed ID: 18613845
• Enhancing Therapeutic Vaccination by Blocking PD-1-mediated Inhibitory Signals During Chronic Infection
  The Journal of Experimental Medicine. Mar, 2008  |   Pubmed ID: 18332181
• Molecular Signature of CD8+ T Cell Exhaustion During Chronic Viral Infection
  Immunity. Oct, 2007  |   Pubmed ID: 17950003
• Enhanced Immunogenicity and Protective Efficacy with the Use of Interleukin-12-encapsulated Microspheres Plus AS01B in Tuberculosis Subunit Vaccination
  Infection and Immunity. Aug, 2006  |   Pubmed ID: 16861689
• Stimulation History Dictates Memory CD8 T Cell Phenotype: Implications for Prime-boost Vaccination
  Journal of Immunology (Baltimore, Md. : 1950). Jul, 2006  |   Pubmed ID: 16818737
• Enhancement of Interleukin-12 Gene-based Tumor Immunotherapy by the Reduced Secretion of P40 Subunit and the Combination with Farnesyltransferase Inhibitor
  Human Gene Therapy. Mar, 2005  |   Pubmed ID: 15812228
• IL-12 Priming During in Vitro Antigenic Stimulation Changes Properties of CD8 T Cells and Increases Generation of Effector and Memory Cells
  Journal of Immunology (Baltimore, Md. : 1950). Mar, 2004  |   Pubmed ID: 14978082
• IL-23 Induces Stronger Sustained CTL and Th1 Immune Responses Than IL-12 in Hepatitis C Virus Envelope Protein 2 DNA Immunization
  Journal of Immunology (Baltimore, Md. : 1950). Jan, 2004  |   Pubmed ID: 14688363