Schuichi Koizumi Department of Neuropharmacology, Faculty of Medicine University of Yamanashi Biography Publications Institution JoVE Articles Schuichi Koizumi has not added a biography. If you are Schuichi Koizumi and would like to personalize this page please email our Author Liaison for assistance. Publications Ischemic Tolerance Induced by Glial Cells Neurochemical Research. Aug, 2022 | Pubmed ID: 35920970 Controlled Activation of Cortical Astrocytes Modulates Neuropathic Pain-like Behaviour Nature Communications. Jul, 2022 | Pubmed ID: 35835747 P2X7 Receptors in Astrocytes: A Switch for Ischemic Tolerance Molecules (Basel, Switzerland). Jun, 2022 | Pubmed ID: 35744780 Transient Astrocytic MGluR5 Expression Drives Synaptic Plasticity and Subsequent Chronic Pain in Mice The Journal of Experimental Medicine. 04, 2022 | Pubmed ID: 35319723 Effects of Fatty Acid Metabolites on Nocturia Scientific Reports. 02, 2022 | Pubmed ID: 35197540 Phagocytic Astrocytes: Emerging from the Shadows of Microglia Glia. Jun, 2022 | Pubmed ID: 35142399 The Mlc1 Promoter Directs Müller Cell-specific Gene Expression in the Retina Translational Vision Science & Technology. 01, 2022 | Pubmed ID: 35040915 Glial Purinergic Signals and Psychiatric Disorders Frontiers in Cellular Neuroscience. 2021 | Pubmed ID: 35069121 Abnormal Ca Signals in Reactive Astrocytes As a Common Cause of Brain Diseases International Journal of Molecular Sciences. Dec, 2021 | Pubmed ID: 35008573 Glial Pharmacology in Asia & Beyond Pharmacology Research & Perspectives. 12, 2021 | Pubmed ID: 34676997 Goshajinkigan Attenuates Paclitaxel-induced Neuropathic Pain Via Cortical Astrocytes Pharmacology Research & Perspectives. 12, 2021 | Pubmed ID: 34676996 Adenosine A Receptor Down-regulates Metabotropic Glutamate Receptor 5 in Astrocytes During Postnatal Development Glia. 11, 2021 | Pubmed ID: 34339538 Transnasal Transplantation of Human Induced Pluripotent Stem Cell-derived Microglia to the Brain of Immunocompetent Mice Glia. 10, 2021 | Pubmed ID: 34309082 Loss of P2Y Receptors Triggers Glaucoma-like Pathology in Mice British Journal of Pharmacology. 11, 2021 | Pubmed ID: 34309010 Neutrophils Initiate and Exacerbate Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Science Translational Medicine. 06, 2021 | Pubmed ID: 34193610 Mechanical Stretch-induced ATP Release from Keratinocytes Triggers Koebner Phenomenon in Psoriasis Journal of Dermatological Science. Jul, 2021 | Pubmed ID: 34187740 Mechanisms Underlying Sensitization of P2X7 Receptors in Astrocytes for Induction of Ischemic Tolerance Glia. 09, 2021 | Pubmed ID: 34076906 Different Effects of GsMTx4 on Nocturia Associated with the Circadian Clock and Piezo1 Expression in Mice Life Sciences. Aug, 2021 | Pubmed ID: 33930366 Reactive Astrocyte-driven Epileptogenesis is Induced by Microglia Initially Activated Following Status Epilepticus JCI Insight. 05, 2021 | Pubmed ID: 33830944 Potential Roles of Astrocytes and Müller Cells in the Pathogenesis of Glaucoma Journal of Pharmacological Sciences. Mar, 2021 | Pubmed ID: 33602506 Reactive Astrocyte Nomenclature, Definitions, and Future Directions Nature Neuroscience. 03, 2021 | Pubmed ID: 33589835 Extracellular ATP Augments Antigen-Induced Murine Mast Cell Degranulation and Allergic Responses Via P2X4 Receptor Activation Journal of Immunology (Baltimore, Md. : 1950). 06, 2020 | Pubmed ID: 32358018 [Pathogenic Roles of Retinal Glia in Glaucoma] Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 2020 | Pubmed ID: 32115484 Author Correction: Intermittent Restraint Stress Induces Circadian Misalignment in the Mouse Bladder, Leading to Nocturia Scientific Reports. Nov, 2019 | Pubmed ID: 31700120 Snake Venom Rhodocytin Induces Plasma Extravasation Via Toxin-mediated Interactions Between Platelets and Mast Cells Scientific Reports. 11, 2019 | Pubmed ID: 31685912 Intermittent Restraint Stress Induces Circadian Misalignment in the Mouse Bladder, Leading to Nocturia Scientific Reports. 07, 2019 | Pubmed ID: 31296902 Microglial ROCK is Essential for Chronic Methylmercury-induced Neurodegeneration Journal of Neurochemistry. 10, 2019 | Pubmed ID: 31278875 Evaluation of M1-microglial Activation by Neurotoxic Metals Using Optimized Organotypic Cerebral Slice Cultures The Journal of Toxicological Sciences. 2019 | Pubmed ID: 31270303 Hyaluronan Synthesis Supports Glutamate Transporter Activity Journal of Neurochemistry. 08, 2019 | Pubmed ID: 31188471 Aberrant Calcium Signals in Reactive Astrocytes: A Key Process in Neurological Disorders International Journal of Molecular Sciences. Feb, 2019 | Pubmed ID: 30823575 Neuroprotective Effects of Microglial P2Y Receptors Against Ischemic Neuronal Injury Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 11, 2019 | Pubmed ID: 30334687 [Epileptogenesis Mediated by Glial Cells] Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 2018 | Pubmed ID: 30531096 Microglia Mediate Non-cell-autonomous Cell Death of Retinal Ganglion Cells Glia. 11, 2018 | Pubmed ID: 30375063 Involvement of VNUT-exocytosis in Transient Receptor Potential Vanilloid 4-dependent ATP Release from Gastrointestinal Epithelium PloS One. 2018 | Pubmed ID: 30365528 The Time-dependent Variation of ATP Release in Mouse Primary-cultured Urothelial Cells is Regulated by the Clock Gene Neurourology and Urodynamics. 11, 2018 | Pubmed ID: 30106187 Anti-Depressant Fluoxetine Reveals Its Therapeutic Effect Via Astrocytes EBioMedicine. Jun, 2018 | Pubmed ID: 29887330 The Oscillation of Intracellular Ca Influx Associated with the Circadian Expression of Piezo1 and TRPV4 in the Bladder Urothelium Scientific Reports. 04, 2018 | Pubmed ID: 29632308 Aberrant Astrocyte Ca Signals "AxCa Signals" Exacerbate Pathological Alterations in an Alexander Disease Model Glia. 05, 2018 | Pubmed ID: 29383757 New Roles of Reactive Astrocytes in the Brain; an Organizer of Cerebral Ischemia Neurochemistry International. 10, 2018 | Pubmed ID: 29360494 Role of Purinergic Receptor P2Y1 in Spatiotemporal Ca Dynamics in Astrocytes The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 02, 2018 | Pubmed ID: 29305530 Astrocytes As Therapeutic Targets in Brain Diseases Neuroscience Research. 01, 2018 | Pubmed ID: 29289274 Astrocytes and Ischemic Tolerance Neuroscience Research. Jan, 2018 | Pubmed ID: 29225139 The Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT, Associated with the Expression Levels of the Clock Genes in Mouse Primary Cultured Urothelial Cells Neurourology and Urodynamics. 03, 2018 | Pubmed ID: 28881406 Author Correction: Reactive Astrocytes Function As Phagocytes After Brain Ischemia Via ABCA1-mediated Pathway Nature Communications. 11, 2017 | Pubmed ID: 29138397 Purinergic Dysregulation Causes Hypertensive Glaucoma-like Optic Neuropathy JCI Insight. 10, 2017 | Pubmed ID: 28978804 Polymorphic Regulation of Mitochondrial Fission and Fusion Modifies Phenotypes of Microglia in Neuroinflammation Scientific Reports. 07, 2017 | Pubmed ID: 28694451 Reactive Astrocytes Function As Phagocytes After Brain Ischemia Via ABCA1-mediated Pathway Nature Communications. 06, 2017 | Pubmed ID: 28642575 Unconventional Role of Voltage-gated Proton Channels (VSOP/Hv1) in Regulation of Microglial ROS Production Journal of Neurochemistry. 09, 2017 | Pubmed ID: 28628214 Astrocyte-mediated Synapse Remodeling in the Pathological Brain Glia. 11, 2017 | Pubmed ID: 28569048 Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia Via P2Y Receptor Downregulation Cell Reports. 05, 2017 | Pubmed ID: 28494865 Pathologic Active MTOR Mutation in Brain Malformation with Intractable Epilepsy Leads to Cell-Autonomous Migration Delay The American Journal of Pathology. May, 2017 | Pubmed ID: 28427592 P2Y-deficiency Increases Micturition Frequency and Attenuates Sustained Contractility of the Urinary Bladder in Mice Scientific Reports. 04, 2017 | Pubmed ID: 28396595 Carbenoxolone Inhibits TRPV4 Channel-initiated Oxidative Urothelial Injury and Ameliorates Cyclophosphamide-induced Bladder Dysfunction Journal of Cellular and Molecular Medicine. Feb, 2017 | Pubmed ID: 28244642 Hypoxia-independent Mechanisms of HIF-1α Expression in Astrocytes After Ischemic Preconditioning Glia. 03, 2017 | Pubmed ID: 28063215 Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa PloS One. 2017 | Pubmed ID: 28060940 The Clock Mutant Mouse is a Novel Experimental Model for Nocturia and Nocturnal Polyuria Neurourology and Urodynamics. Apr, 2017 | Pubmed ID: 27348079 An Effective Therapeutic Approach for Oxaliplatin-induced Peripheral Neuropathy Using a Combination Therapy with Goshajinkigan and Bushi Cancer Biology & Therapy. 11, 2016 | Pubmed ID: 27416484 Urothelial ATP Exocytosis: Regulation of Bladder Compliance in the Urine Storage Phase Scientific Reports. 07, 2016 | Pubmed ID: 27412485 Cortical Astrocytes Rewire Somatosensory Cortical Circuits for Peripheral Neuropathic Pain The Journal of Clinical Investigation. May, 2016 | Pubmed ID: 27064281 Origins of Oligodendrocytes in the Cerebellum, Whose Development is Controlled by the Transcription Factor, Sox9 Mechanisms of Development. 05, 2016 | Pubmed ID: 26940020 Müller Cell-mediated Neurite Outgrowth of the Retinal Ganglion Cells Via P2Y Receptor Signals Journal of Neurochemistry. Feb, 2016 | Pubmed ID: 26560804 Astrocyte-mediated Ischemic Tolerance The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2015 | Pubmed ID: 25740510 Long-term Imipramine Treatment Increases N-methyl-d-aspartate Receptor Activity and Expression Via Epigenetic Mechanisms European Journal of Pharmacology. Apr, 2015 | Pubmed ID: 25701723 TRPV4 Regulates the Integrity of the Blood-cerebrospinal Fluid Barrier and Modulates Transepithelial Protein Transport FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2015 | Pubmed ID: 25681460 Expression of Astrocyte-related Receptors in Cortical Dysplasia with Intractable Epilepsy Journal of Neuropathology and Experimental Neurology. Aug, 2014 | Pubmed ID: 25003238 Functional Role for Piezo1 in Stretch-evoked Ca²⁺ Influx and ATP Release in Urothelial Cell Cultures The Journal of Biological Chemistry. Jun, 2014 | Pubmed ID: 24759099 Microglia Trigger Astrocyte-mediated Neuroprotection Via Purinergic Gliotransmission Scientific Reports. Mar, 2014 | Pubmed ID: 24710318 Mechanism Underlying ATP Release in Human Epidermal Keratinocytes The Journal of Investigative Dermatology. May, 2014 | Pubmed ID: 24292772 Involvement of Glial P2Y₁ Receptors in Cognitive Deficit After Focal Cerebral Stroke in a Rodent Model Journal of Neuroinflammation. Jul, 2013 | Pubmed ID: 23890321 Microglia Release ATP by Exocytosis Glia. Aug, 2013 | Pubmed ID: 23832620 Astrocytes Protect Neurons Against Methylmercury Via ATP/P2Y(1) Receptor-mediated Pathways in Astrocytes PloS One. 2013 | Pubmed ID: 23469098 In Vitro Blood-brain Barrier Models Using Brain Capillary Endothelial Cells Isolated from Neonatal and Adult Rats Retain Age-related Barrier Properties PloS One. 2013 | Pubmed ID: 23383092 Secretion of Matrix Metalloproteinase-9 from Astrocytes by Inhibition of Tonic P2Y14-receptor-mediated Signal(s) Cellular and Molecular Neurobiology. Jan, 2013 | Pubmed ID: 22872320 Purinergic Receptors in Microglia: Functional Modal Shifts of Microglia Mediated by P2 and P1 Receptors Glia. Jan, 2013 | Pubmed ID: 22674620 Purinergic Signaling Promotes Proliferation of Adult Mouse Subventricular Zone Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2012 | Pubmed ID: 22764232 Cell-autonomous Enhancement of Glutamate-uptake by Female Astrocytes Cellular and Molecular Neurobiology. Aug, 2012 | Pubmed ID: 22450870 Severe Dermatitis with Loss of Epidermal Langerhans Cells in Human and Mouse Zinc Deficiency The Journal of Clinical Investigation. Feb, 2012 | Pubmed ID: 22214844 The Astrocyte-targeted Therapy by Bushi for the Neuropathic Pain in Mice PloS One. 2011 | Pubmed ID: 21876755 Nonsteroidal Anti-inflammatory Drug Flufenamic Acid is a Potent Activator of AMP-activated Protein Kinase The Journal of Pharmacology and Experimental Therapeutics. Oct, 2011 | Pubmed ID: 21765041 In Vivo Canine Model Comparison of Cardiovascular Effects of Antidepressants Milnacipran and Imipramine Cardiovascular Toxicology. Dec, 2010 | Pubmed ID: 20680703 Synchronization of Ca2+ Oscillations: Involvement of ATP Release in Astrocytes The FEBS Journal. Jan, 2010 | Pubmed ID: 19895581 The TRPV4 Cation Channel Mediates Stretch-evoked Ca2+ Influx and ATP Release in Primary Urothelial Cell Cultures The Journal of Biological Chemistry. Aug, 2009 | Pubmed ID: 19531473 Direct Observation of ATP-induced Conformational Changes in Single P2X(4) Receptors PLoS Biology. May, 2009 | Pubmed ID: 19419241 Grape Seed Extract Acting on Astrocytes Reveals Neuronal Protection Against Oxidative Stress Via Interleukin-6-mediated Mechanisms Cellular and Molecular Neurobiology. Dec, 2009 | Pubmed ID: 19381798 [Regulation of Brain Function Mediated by Glial ATP Sensors] Seikagaku. The Journal of Japanese Biochemical Society. Jan, 2009 | Pubmed ID: 19260453 The Role of Nucleotides in the Neuron--glia Communication Responsible for the Brain Functions Journal of Neurochemistry. Sep, 2007 | Pubmed ID: 17697046 Reduced Pain Behaviors and Extracellular Signal-related Protein Kinase Activation in Primary Sensory Neurons by Peripheral Tissue Injury in Mice Lacking Platelet-activating Factor Receptor Journal of Neurochemistry. Sep, 2007 | Pubmed ID: 17662046 UDP Acting at P2Y6 Receptors is a Mediator of Microglial Phagocytosis Nature. Apr, 2007 | Pubmed ID: 17410128 في الجسم الحي تصوير الكالسيوم واسع المجال وثنائي الفوتون من فأر باستخدام نافذة جمجمة كبيرة Satoshi Manita1, Eiji Shigetomi2,3, Haruhiko Bito4, Schuichi Koizumi2,3, Kazuo Kitamura1 1Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, 2Department of Neuropharmacology, Faculty of Medicine, University of Yamanashi, 3Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 4Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo JoVE 64224 Neuroscience زرع الخلايا الدبقية الصغيرة المشتقة من الخلايا الجذعية متعددة القدرات التي يسببها الإنسان في دماغ الفئران المناعية عبر طريق الأنف غير الغازي Bijay Parajuli1,2, Youichi Shinozaki1,2, Eiji Shigetomi1,2, Schuichi Koizumi1,2 1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi JoVE 63574 Neuroscience
في الجسم الحي تصوير الكالسيوم واسع المجال وثنائي الفوتون من فأر باستخدام نافذة جمجمة كبيرة Satoshi Manita1, Eiji Shigetomi2,3, Haruhiko Bito4, Schuichi Koizumi2,3, Kazuo Kitamura1 1Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, 2Department of Neuropharmacology, Faculty of Medicine, University of Yamanashi, 3Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 4Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo JoVE 64224 Neuroscience
زرع الخلايا الدبقية الصغيرة المشتقة من الخلايا الجذعية متعددة القدرات التي يسببها الإنسان في دماغ الفئران المناعية عبر طريق الأنف غير الغازي Bijay Parajuli1,2, Youichi Shinozaki1,2, Eiji Shigetomi1,2, Schuichi Koizumi1,2 1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi JoVE 63574 Neuroscience
