Articles by Sergey Etchin in JoVE
原位压极限和骨牙周韧带齿纤维联合的相关性无创成像 Andrew T. Jang1, Jeremy D. Lin1, Youngho Seo2, Sergey Etchin3, Arno Merkle3, Kevin Fahey3, Sunita P. Ho1 1Division of Biomaterials and Bioengineering, Department of Preventive and Restorative Dental Sciences, University of California San Francisco, 2Department of Radiology and Biomedical Imaging, University of California San Francisco, 3Xradia Inc. 在这项研究中， 在加上微X射线计算机断层摄影术为纤维状关节生物力学原位装载装置使用一个将被讨论。识别与关节生物力学的整体改变的实验读数将包括：1）反动力与位移，在牙槽窝内，即牙齿位移及其装载反动响应，2）三维（3D）空间构型和形态测量， 即几何齿与齿槽插座，和3）中读出1和2的变化是由于在加载轴， 即同心或偏心载荷的变化关系。
Other articles by Sergey Etchin on PubMed
Accurate Whole Human Genome Sequencing Using Reversible Terminator Chemistry Nature. Nov, 2008 | Pubmed ID: 18987734 DNA sequence information underpins genetic research, enabling discoveries of important biological or medical benefit. Sequencing projects have traditionally used long (400-800 base pair) reads, but the existence of reference sequences for the human and many other genomes makes it possible to develop new, fast approaches to re-sequencing, whereby shorter reads are compared to a reference to identify intraspecies genetic variation. Here we report an approach that generates several billion bases of accurate nucleotide sequence per experiment at low cost. Single molecules of DNA are attached to a flat surface, amplified in situ and used as templates for synthetic sequencing with fluorescent reversible terminator deoxyribonucleotides. Images of the surface are analysed to generate high-quality sequence. We demonstrate application of this approach to human genome sequencing on flow-sorted X chromosomes and then scale the approach to determine the genome sequence of a male Yoruba from Ibadan, Nigeria. We build an accurate consensus sequence from >30x average depth of paired 35-base reads. We characterize four million single-nucleotide polymorphisms and four hundred thousand structural variants, many of which were previously unknown. Our approach is effective for accurate, rapid and economical whole-genome re-sequencing and many other biomedical applications.