Shai Izraeli Cancer Research Center Sheba Medical Center Biography Publications Institution JoVE Articles Shai Izraeli has not added a biography. If you are Shai Izraeli and would like to personalize this page please email our Author Liaison for assistance. Publications Perturbation of Fetal Hematopoiesis in a Mouse Model of Down Syndrome's Transient Myeloproliferative Disorder Blood. Aug, 2013 | Pubmed ID: 23719302 Interleukin 7 and Thymic Stromal Lymphopoietin: from Immunity to Leukemia Cellular and Molecular Life Sciences : CMLS. Apr, 2013 | Pubmed ID: 23625073 Identification of Regulators of Polyploidization Presents Therapeutic Targets for Treatment of AMKL Cell. Aug, 2012 | Pubmed ID: 22863010 Cell Lineage Analysis of Acute Leukemia Relapse Uncovers the Role of Replication-rate Heterogeneity and Microsatellite Instability Blood. Jul, 2012 | Pubmed ID: 22645183 Spontaneous Remission of Childhood Acute Marrow Fibrosis and Megakaryoblastic Leukemia Journal of Pediatric Hematology/oncology. Oct, 2012 | Pubmed ID: 22627572 DYRK1A in Down Syndrome: an Oncogene or Tumor Suppressor? The Journal of Clinical Investigation. Mar, 2012 | Pubmed ID: 22354166 STIL is Required for Centriole Duplication in Human Cells Journal of Cell Science. Mar, 2012 | Pubmed ID: 22349705 A Phenanthrene Derived PARP Inhibitor is an Extra-centrosomes De-clustering Agent Exclusively Eradicating Human Cancer Cells BMC Cancer. 2011 | Pubmed ID: 21943092 Large-scale Analysis of Chromosomal Aberrations in Cancer Karyotypes Reveals Two Distinct Paths to Aneuploidy Genome Biology. 2011 | Pubmed ID: 21714908 ERG Promotes T-acute Lymphoblastic Leukemia and is Transcriptionally Regulated in Leukemic Cells by a Stem Cell Enhancer Blood. Jun, 2011 | Pubmed ID: 21536859 Gain-of-function Mutations in Interleukin-7 Receptor-α (IL7R) in Childhood Acute Lymphoblastic Leukemias The Journal of Experimental Medicine. May, 2011 | Pubmed ID: 21536738 The Stil Protein Regulates Centrosome Integrity and Mitosis Through Suppression of Chfr Journal of Cell Science. Feb, 2011 | Pubmed ID: 21245198 Therapy-related Acute Myeloid Leukemia with T(2;11)(q37;q23) After Treatment for Osteosarcoma Cancer Genetics and Cytogenetics. Dec, 2010 | Pubmed ID: 21156246 Similar Yet Different Blood. Aug, 2010 | Pubmed ID: 20724545 Detection of Prognostically Relevant Genetic Abnormalities in Childhood B-cell Precursor Acute Lymphoblastic Leukaemia: Recommendations from the Biology and Diagnosis Committee of the International Berlin-Frankfürt-Münster Study Group British Journal of Haematology. Oct, 2010 | Pubmed ID: 20701601 Application of Genomics for Risk Stratification of Childhood Acute Lymphoblastic Leukaemia: from Bench to Bedside? British Journal of Haematology. Oct, 2010 | Pubmed ID: 20678159 Prospective Comparison of Two Flow Cytometry Methodologies for Monitoring Minimal Residual Disease in a Multicenter Treatment Protocol of Childhood Acute Lymphoblastic Leukemia Cytometry. Part B, Clinical Cytometry. Nov, 2010 | Pubmed ID: 20632326 Presence of the P2RY8-CRLF2 Rearrangement is Associated with a Poor Prognosis in Non-high-risk Precursor B-cell Acute Lymphoblastic Leukemia in Children Treated According to the ALL-BFM 2000 Protocol Blood. Jul, 2010 | Pubmed ID: 20378752 Where Can Biology of Childhood ALL Be Attacked by New Compounds? Cancer Treatment Reviews. Jun, 2010 | Pubmed ID: 20223597 A Rare Case of GATA1 Negative Chemoresistant Acute Megakaryocytic Leukemia in an 8-month-old Infant with Trisomy 21 Pediatric Blood & Cancer. Jul, 2010 | Pubmed ID: 20108342 Down Syndrome Acute Lymphoblastic Leukemia, a Highly Heterogeneous Disease in Which Aberrant Expression of CRLF2 is Associated with Mutated JAK2: a Report from the International BFM Study Group Blood. Feb, 2010 | Pubmed ID: 19965641 Detection of Residual B Precursor Lymphoblastic Leukemia by Uniform Gating Flow Cytometry Pediatric Blood & Cancer. Jan, 2010 | Pubmed ID: 19760767 A Selective Eradication of Human Nonhereditary Breast Cancer Cells by Phenanthridine-derived PolyADP-ribose Polymerase Inhibitors Breast Cancer Research : BCR. 2009 | Pubmed ID: 19891779 Extended Triple Intrathecal Therapy in Children with T-cell Acute Lymphoblastic Leukaemia: a Report from the Israeli National ALL-Studies British Journal of Haematology. Oct, 2009 | Pubmed ID: 19694717 ERG is a Megakaryocytic Oncogene Cancer Research. Jun, 2009 | Pubmed ID: 19487285 Constitutional Aneuploidy and Cancer Predisposition Human Molecular Genetics. Apr, 2009 | Pubmed ID: 19297405 Diagnostic Assay Based on Hsa-miR-205 Expression Distinguishes Squamous from Nonsquamous Non-small-cell Lung Carcinoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Apr, 2009 | Pubmed ID: 19273703 The Expression of Three Genes in Primary Non-small Cell Lung Cancer is Associated with Metastatic Spread to the Brain Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2009 | Pubmed ID: 19190132 Insights into the Manifestations, Outcomes, and Mechanisms of Leukemogenesis in Down Syndrome Blood. Mar, 2009 | Pubmed ID: 19139078 Prevalence and Clinical Correlates of JAK2 Mutations in Down Syndrome Acute Lymphoblastic Leukaemia British Journal of Haematology. Mar, 2009 | Pubmed ID: 19120350 Trisomy 21 Tilts the Balance Blood. Dec, 2008 | Pubmed ID: 19029447 Mutations of JAK2 in Acute Lymphoblastic Leukaemias Associated with Down's Syndrome Lancet. Oct, 2008 | Pubmed ID: 18805579 The Mitotic Checkpoint Gene, SIL is Regulated by E2F1 International Journal of Cancer. Journal International Du Cancer. Oct, 2008 | Pubmed ID: 18649360 Array Comparative Genome Hybridization Analysis of Acute Lymphoblastic Leukaemia and Acute Megakaryoblastic Leukaemia in Patients with Down Syndrome British Journal of Haematology. Sep, 2008 | Pubmed ID: 18557744 ETV6-NCOA2: a Novel Fusion Gene in Acute Leukemia Associated with Coexpression of T-lymphoid and Myeloid Markers and Frequent NOTCH1 Mutations Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2008 | Pubmed ID: 18281529 Integration of a Palliative and Terminal Care Center into a Comprehensive Pediatric Oncology Department Pediatric Blood & Cancer. May, 2008 | Pubmed ID: 18240176 Cytogenetic Features of Acute Lymphoblastic and Myeloid Leukemias in Pediatric Patients with Down Syndrome: an IBFM-SG Study Blood. Feb, 2008 | Pubmed ID: 17971484 Acute Lymphoblastic Leukemia in Children: Correlation of Musculoskeletal Manifestations and Immunophenotypes Journal of Children's Orthopaedics. Mar, 2007 | Pubmed ID: 19308508 Biased Exonization of Transposed Elements in Duplicated Genes: A Lesson from the TIF-IA Gene BMC Molecular Biology. 2007 | Pubmed ID: 18047649 High Interleukin-15 Expression Characterizes Childhood Acute Lymphoblastic Leukemia with Involvement of the CNS Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2007 | Pubmed ID: 17947730 Trisomy of Chromosome 21 in Leukemogenesis Blood Cells, Molecules & Diseases. Sep-Oct, 2007 | Pubmed ID: 17532652 STOP: Searching for Transcription Factor Motifs Using Gene Expression Bioinformatics (Oxford, England). Jul, 2007 | Pubmed ID: 17488754 The SIL Gene is Essential for Mitotic Entry and Survival of Cancer Cells Cancer Research. May, 2007 | Pubmed ID: 17456584 Prediction of Chromosomal Aneuploidy from Gene Expression Data Genes, Chromosomes & Cancer. Jan, 2007 | Pubmed ID: 17044051 The SCL 3' Enhancer Responds to Hedgehog Signaling During Hemangioblast Specification Experimental Hematology. Dec, 2006 | Pubmed ID: 17157160 Down's Syndrome As a Model of a Pre-leukemic Condition Haematologica. Nov, 2006 | Pubmed ID: 17082004 Molecular Pathways Regulating Pro-migratory Effects of Hedgehog Signaling The Journal of Biological Chemistry. Nov, 2006 | Pubmed ID: 16943197 Myeloid Dysplasia in Familial 3-methylglutaconic Aciduria Journal of Pediatric Hematology/oncology. Feb, 2006 | Pubmed ID: 16462576 Perspective: Chromosomal Aneuploidy in Leukemia--lessons from Down Syndrome Hematological Oncology. Mar, 2006 | Pubmed ID: 16270377 Epidermal Growth Factor Receptor Gene Amplification and Expression in Disseminated Pediatric Low-grade Gliomas Journal of Neurosurgery. Oct, 2005 | Pubmed ID: 16270688 Chromosome Copy Number and Leukemia-lessons from Down's Syndrome Hematology (Amsterdam, Netherlands). 2005 | Pubmed ID: 16188662 The Proto-oncogene ERG in Megakaryoblastic Leukemias Cancer Research. Sep, 2005 | Pubmed ID: 16140924 Sil Phosphorylation in a Pin1 Binding Domain Affects the Duration of the Spindle Checkpoint Molecular and Cellular Biology. Aug, 2005 | Pubmed ID: 16024801 Gene Expression Analysis Reveals a Strong Signature of an Interferon-induced Pathway in Childhood Lymphoblastic Leukemia As Well As in Breast and Ovarian Cancer Oncogene. Sep, 2005 | Pubmed ID: 16007187 Co-existence of Multiple Subclones in TEL-AML1 at Diagnosis of Acute Lymphoblastic Leukaemia in Association with Submicroscopic Deletion of AML1 British Journal of Haematology. May, 2005 | Pubmed ID: 15877731 Histone Deacetylase Inhibitors--a New Tool to Treat Cancer Cancer Treatment Reviews. Aug, 2004 | Pubmed ID: 15245778 Leukaemia -- a Developmental Perspective British Journal of Haematology. Jul, 2004 | Pubmed ID: 15198727 Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia: Current Status and Challenges Acta Haematologica. 2004 | Pubmed ID: 15179003 Mitochondrial Pro-apoptotic ARTS Protein is Lost in the Majority of Acute Lymphoblastic Leukemia Patients Oncogene. Jul, 2004 | Pubmed ID: 15122323 Sil Overexpression in Lung Cancer Characterizes Tumors with Increased Mitotic Activity Oncogene. Jul, 2004 | Pubmed ID: 15107824 Kidney, Blood, and Endothelium: Developmental Expression of Stem Cell Leukemia During Nephrogenesis Kidney International. Apr, 2004 | Pubmed ID: 15086455 Congenital Syndromes and Leukemia: Clues to Pathogenesis Reviews in Clinical and Experimental Hematology. Sep, 2003 | Pubmed ID: 15024968 Mutations in Exon 2 of GATA1 Are Early Events in Megakaryocytic Malignancies Associated with Trisomy 21 Blood. Aug, 2003 | Pubmed ID: 12649131 Cancer Research--from Bench to Bedside The Israel Medical Association Journal : IMAJ. Sep, 2002 | Pubmed ID: 12440253 Molecular Medicine--an Overview The Israel Medical Association Journal : IMAJ. Aug, 2002 | Pubmed ID: 12183874 GLI3 is Not Mutated Commonly in Sporadic Medulloblastomas Cancer. Jul, 2002 | Pubmed ID: 12115313 Сотовые смерти, связанной с аномальными митоза Наблюдаемые конфокальной микроскопии в живых клетках рака Asher Castiel1, Leonid Visochek2,3, Leonid Mittelman4, Yael Zilberstein4, Francoise Dantzer5, Shai Izraeli1,6, Malka Cohen-Armon2,3 1Cancer Research Center, Sheba Medical Center, 2The Neufeld Cardiac Research Institute, Tel-Aviv University, 3Department of Physiology and Pharmacology, Tel-Aviv University, 4Imaging Unit, Sackler Faculty of Medicine, Tel-Aviv University, 5Biotechnology and Cell Signaling, Ecole Superieure de Biotechnologie Strasbourg, 6Department of Human Molecular Genetics and Biochemistry, Tel-Aviv University JoVE 50568 Medicine
Сотовые смерти, связанной с аномальными митоза Наблюдаемые конфокальной микроскопии в живых клетках рака Asher Castiel1, Leonid Visochek2,3, Leonid Mittelman4, Yael Zilberstein4, Francoise Dantzer5, Shai Izraeli1,6, Malka Cohen-Armon2,3 1Cancer Research Center, Sheba Medical Center, 2The Neufeld Cardiac Research Institute, Tel-Aviv University, 3Department of Physiology and Pharmacology, Tel-Aviv University, 4Imaging Unit, Sackler Faculty of Medicine, Tel-Aviv University, 5Biotechnology and Cell Signaling, Ecole Superieure de Biotechnologie Strasbourg, 6Department of Human Molecular Genetics and Biochemistry, Tel-Aviv University JoVE 50568 Medicine