Shuang Chen Department of Gastroenterological Surgery and Hernia Center, The Sixth Affiliated Hospital, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangzhou Sun Yat-sen University Biography Publications Institution JoVE Articles Shuang Chen has not added a biography. If you are Shuang Chen and would like to personalize this page please email our Author Liaison for assistance. Publications Cuproptosis-related Long Non-coding RNAs Model That Effectively Predicts Prognosis in Hepatocellular Carcinoma World Journal of Gastrointestinal Oncology. Oct, 2022 | Pubmed ID: 36310708 A Novel Senescence-associated LncRNA Signature Predicts the Prognosis and Tumor Microenvironment of Patients with Colorectal Cancer: a Bioinformatics Analysis Journal of Gastrointestinal Oncology. Aug, 2022 | Pubmed ID: 36092325 The Development and Validation of a Novel Senescence-related Long-chain Non-coding RNA (lncRNA) Signature That Predicts Prognosis and the Tumor Microenvironment of Patients with Hepatocellular Carcinoma Annals of Translational Medicine. Jul, 2022 | Pubmed ID: 35965795 N-methylguanosine TRNA Modification Promotes Esophageal Squamous Cell Carcinoma Tumorigenesis Via the RPTOR/ULK1/autophagy Axis Nature Communications. Mar, 2022 | Pubmed ID: 35304469 Circular RNA Protein Tyrosine Kinase 2 (circPTK2) Promotes Colorectal Cancer Proliferation, Migration, Invasion and Chemoresistance Bioengineered. Jan, 2022 | Pubmed ID: 34974791 Sox9 Cells Are Required for Salivary Gland Regeneration After Radiation Damage Via the Wnt/β-catenin Pathway Journal of Genetics and Genomics = Yi Chuan Xue Bao. Mar, 2022 | Pubmed ID: 34757039 Botulinum Toxin A Facilitated Laparoscopic Repair of Complex Ventral Hernia Frontiers in Surgery. 2021 | Pubmed ID: 35083273 Circ-RNF121 Regulates Tumor Progression and Glucose Metabolism by MiR-1224-5p/FOXM1 Axis in Colorectal Cancer Cancer Cell International. Nov, 2021 | Pubmed ID: 34742305 Methyltransferase Like 13 Mediates the Translation of Snail in Head and Neck Squamous Cell Carcinoma International Journal of Oral Science. Aug, 2021 | Pubmed ID: 34381012 Longitudinal Rehabilitation of Binocular Function in Adolescent Intermittent Exotropia After Successful Corrective Surgery Frontiers in Neuroscience. 2021 | Pubmed ID: 34290584 EIF4A3-induced Circ_0084615 Contributes to the Progression of Colorectal Cancer Via MiR-599/ONECUT2 Pathway Journal of Experimental & Clinical Cancer Research : CR. Jul, 2021 | Pubmed ID: 34253241 Sox9-expressing Cells Promote Regeneration After Radiation-induced Lung Injury Via the PI3K/AKT Pathway Stem Cell Research & Therapy. Jul, 2021 | Pubmed ID: 34215344 Preoperative Progressive Pneumoperitoneum and Botulinum Toxin Type A in Patients With Large Parastomal Hernia Frontiers in Surgery. 2021 | Pubmed ID: 34164428 Exosomal CircEPB41L2 Serves As a Sponge for MiR-21-5p and MiR-942-5p to Suppress Colorectal Cancer Progression by Regulating the PTEN/AKT Signalling Pathway European Journal of Clinical Investigation. Sep, 2021 | Pubmed ID: 34022068 Downregulating Long Non-coding RNAs CTBP1-AS2 Inhibits Colorectal Cancer Development by Modulating the MiR-93-5p/TGF-β/SMAD2/3 Pathway Frontiers in Oncology. 2021 | Pubmed ID: 33937030 Corrigendum: Deficiency of Mettl3 in Bladder Cancer Stem Cells Inhibits Bladder Cancer Progression and Angiogenesis Frontiers in Cell and Developmental Biology. 2021 | Pubmed ID: 33842490 Circ-Keratin 6c Promotes Malignant Progression and Immune Evasion of Colorectal Cancer Through MicroRNA-485-3p/Programmed Cell Death Receptor Ligand 1 Axis The Journal of Pharmacology and Experimental Therapeutics. Jun, 2021 | Pubmed ID: 33771844 Tumor Microenvironment in Head and Neck Squamous Cell Carcinoma: Functions and Regulatory Mechanisms Cancer Letters. Jun, 2021 | Pubmed ID: 33741424 Deficiency of Mettl3 in Bladder Cancer Stem Cells Inhibits Bladder Cancer Progression and Angiogenesis Frontiers in Cell and Developmental Biology. 2021 | Pubmed ID: 33681207 Cervical Extension of the Normal Thymus in Children and Adolescents: Sonographic Features and Prevalence Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Nov, 2021 | Pubmed ID: 33491815 CT-derived Abdominal Adiposity: Distributions and Better Predictive Ability Than BMI in a Nationwide Study of 59,429 Adults in China Metabolism: Clinical and Experimental. 02, 2021 | Pubmed ID: 33259834 Opportunistic Screening Using Low-Dose CT and the Prevalence of Osteoporosis in China: A Nationwide, Multicenter Study Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. 03, 2021 | Pubmed ID: 33145809 Expression and Prognostic Value of Chromobox Family Members in Gastric Cancer Journal of Gastrointestinal Oncology. Oct, 2020 | Pubmed ID: 33209492 Preoperative Progressive Pneumoperitoneum Enables Defect Closure and Laparoscopic Repair of Large Parastomal Hernias Surgical Laparoscopy, Endoscopy & Percutaneous Techniques. Apr, 2020 | Pubmed ID: 31985570 Long Non-coding RNA Mortal Obligate RNA Transcript Inhibits the Migration and Invasion of Colon Cancer Cells by Inactivating Transforming Growth Factor β1 Oncology Letters. Feb, 2020 | Pubmed ID: 31966041 Combination of Preoperative Progressive Pneumoperitoneum and Botulinum Toxin A Enables the Laparoscopic Transabdominal Preperitoneal Approach for Repairing Giant Inguinoscrotal Hernias Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A. Mar, 2020 | Pubmed ID: 31794292 LncRNA HAND2-AS1 Inhibits 5-fluorouracil Resistance by Modulating MiR-20a/PDCD4 Axis in Colorectal Cancer Cellular Signalling. Feb, 2020 | Pubmed ID: 31760170 LncRNA PART1 Regulates Colorectal Cancer Via Targeting MiR-150-5p/miR-520h/CTNNB1 and Activating Wnt/β-catenin Pathway The International Journal of Biochemistry & Cell Biology. 01, 2020 | Pubmed ID: 31669140 MiR-1245a Promotes the Proliferation and Invasion of Colon Adenocarcinoma by Targeting BRCA2 Annals of Translational Medicine. Dec, 2019 | Pubmed ID: 32042793 Analysis of TGCA Data Reveals Genetic and Epigenetic Changes and Biological Function of Family Genes in Colorectal Cancer Future Oncology (London, England). Dec, 2019 | Pubmed ID: 31773991 Neoadjuvant Chemotherapy With MFOLFOXIRI Without Routine Use of Radiotherapy for Locally Advanced Rectal Cancer Clinical Colorectal Cancer. 12, 2019 | Pubmed ID: 31378655 Identification of Novel T1D Risk Loci and Their Association With Age and Islet Function at Diagnosis in Autoantibody-Positive T1D Individuals: Based on a Two-Stage Genome-Wide Association Study Diabetes Care. Aug, 2019 | Pubmed ID: 31152121 MiR-145-5p Affects the Differentiation of Gastric Cancer by Targeting KLF5 Directly Journal of Cellular Physiology. May, 2019 | Pubmed ID: 30367481 MicroRNA-128 Targeting RPN2 Inhibits Cell Proliferation and Migration Through the Akt-p53-cyclin Pathway in Colorectal Cancer Cells Oncology Letters. Dec, 2018 | Pubmed ID: 30546426 Cancer-associated Fibroblasts Suppress SOX2-induced Dysplasia in a Lung Squamous Cancer Coculture Proceedings of the National Academy of Sciences of the United States of America. 12, 2018 | Pubmed ID: 30487219 [Repair of Hiatal Hernia Deserves Union of Anatomy and Function of Esophagus] Zhonghua Wei Chang Wai Ke Za Zhi = Chinese Journal of Gastrointestinal Surgery. Jul, 2018 | Pubmed ID: 30051438 [China Guideline for Diagnosis and Treatment of Incisional Hernia (2018 Edition)] Zhonghua Wei Chang Wai Ke Za Zhi = Chinese Journal of Gastrointestinal Surgery. Jul, 2018 | Pubmed ID: 30051436 [China Guideline for Diagnosis and Treatment of Adult Groin Hernia (2018 Edition)] Zhonghua Wei Chang Wai Ke Za Zhi = Chinese Journal of Gastrointestinal Surgery. Jul, 2018 | Pubmed ID: 30051435 [2017 Hotspots Review and Future Prospects of Abdominal Wall and Hernia Surgery] Zhonghua Wei Chang Wai Ke Za Zhi = Chinese Journal of Gastrointestinal Surgery. Jan, 2018 | Pubmed ID: 29354894 Leptin Stimulates Prolactin MRNA Expression in the Goldfish Pituitary Through a Combination of the PI3K/Akt/mTOR, MKK/pMAPK and MEK/ERK Signalling Pathways International Journal of Molecular Sciences. Dec, 2017 | Pubmed ID: 29261147 Ezrin/NF-kB Activation Regulates Epithelial- Mesenchymal Transition Induced by EGF and Promotes Metastasis of Colorectal Cancer Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Aug, 2017 | Pubmed ID: 28535417 Metformin Depresses Overactivated Notch1/Hes1 Signaling in Colorectal Cancer Patients with Type 2 Diabetes Mellitus Anti-cancer Drugs. Jun, 2017 | Pubmed ID: 28177944 Temporary Tube Stoma Versus Conventional Loop Stoma for the Protection of a Low Anastomosis in Colorectal Surgery: A Systematic Review and Meta-analysis The American Surgeon. Mar, 2016 | Pubmed ID: 27099062 Musashi2 As a Novel Predictive Biomarker for Liver Metastasis and Poor Prognosis in Colorectal Cancer Cancer Medicine. Apr, 2016 | Pubmed ID: 26775684 [Mutual Influence and Development Between Gastrointestinal Surgery and Hernia and Abdominal Wall Surgery] Zhonghua Wei Chang Wai Ke Za Zhi = Chinese Journal of Gastrointestinal Surgery. Nov, 2015 | Pubmed ID: 26616795 [Application of Carbon Nanoparticles Labeled Lymph Node Staining in Curative Laparoscopic Resection for Colorectal Carcinoma] Zhonghua Wei Chang Wai Ke Za Zhi = Chinese Journal of Gastrointestinal Surgery. Jun, 2015 | Pubmed ID: 26108766 Long-term Outcome for Open Preperitoneal Mesh Repair of Recurrent Inguinal Hernia International Journal of Surgery (London, England). Jul, 2015 | Pubmed ID: 26021274 Reconstruction of Abdominal Wall Defects Using Small Intestinal Submucosa Coated with Gelatin Hydrogel Incorporating Basic Fibroblast Growth Factor Acta Cirurgica Brasileira. Apr, 2014 | Pubmed ID: 24760026 Repair of Damaged Intestinal Mucosa in a Mouse Model of Sepsis World Journal of Emergency Medicine. 2013 | Pubmed ID: 25215123 KCNN4 Channels Participate in the EMT Induced by PRL-3 in Colorectal Cancer Medical Oncology (Northwood, London, England). 2013 | Pubmed ID: 23572150 Variations of Urinary Bladder and the Urogenital Fatty Fascial Compartment with Different Filling of the Bladder Are Notable Factors Relevant to Hernia Repair-related Bladder Injury The American Surgeon. Feb, 2013 | Pubmed ID: 23336656 Comparison of Duct-to-mucosa and End-to-side Pancreaticojejunostomy Reconstruction Following Pancreaticoduodenectomy Hepato-gastroenterology. 2013 | Pubmed ID: 22773303 Butyrate Interferes with the Differentiation and Function of Human Monocyte-derived Dendritic Cells Cellular Immunology. 2012 | Pubmed ID: 22698927 [Application of Fat Clearance Technique in Pathologic Staging for Colon Cancer] Zhonghua Wei Chang Wai Ke Za Zhi = Chinese Journal of Gastrointestinal Surgery. Jul, 2011 | Pubmed ID: 21792765 PRL-3 Promotes the Proliferation of LoVo Cells Via the Upregulation of KCNN4 Channels Oncology Reports. Oct, 2011 | Pubmed ID: 21725609 [The Influence of Lymph Nodes Detection on Pathological Staging in Rectal Cancer] Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]. Jun, 2010 | Pubmed ID: 21163048 [Open Total Extraperitoneal Herniorrhaphy for Inguinal Hernia Via a Ventral Midline Incision] Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]. Sep, 2010 | Pubmed ID: 21092606 [Meta-analysis of Suture Techniques for Midline Abdominal Incisions] Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]. Aug, 2010 | Pubmed ID: 21055218 [Comparison of Fat Clearance and Fat Lucidification in Examining Rectal Cancer Specimen] Zhonghua Wei Chang Wai Ke Za Zhi = Chinese Journal of Gastrointestinal Surgery. Apr, 2010 | Pubmed ID: 20422484 Randomized Trial on the Application of Biofragmentable Anastomosis Ring in Intestinal Anastomosis Chinese Medical Journal. Aug, 2009 | Pubmed ID: 19781320 [Study on the Tectology Change of Rectum Wall Above the Hemorrhoids] Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]. Jun, 2009 | Pubmed ID: 19781245 [Study on Intra-abdominal Pressure in Indirect Inguinal Hernia Patients] Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]. Nov, 2007 | Pubmed ID: 18275705 [On Certain Issues in Pathogenesis of Inguinal Hernia] Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]. Nov, 2007 | Pubmed ID: 18275701 [Therapeutic Comparison Between Procedure for Prolapse and Hemorrhoids and Ligasure Technique for Hemorrhoids] Zhonghua Wei Chang Wai Ke Za Zhi = Chinese Journal of Gastrointestinal Surgery. Jul, 2007 | Pubmed ID: 17659458 [Effect of Goblet Cell in Rat Intestine on the Restitution Process of the Gut Barrier After Hemorrhagic Shock] Zhonghua Wei Chang Wai Ke Za Zhi = Chinese Journal of Gastrointestinal Surgery. Nov, 2005 | Pubmed ID: 16299653 [Risk Factors for Postoperative Pulmonary Complications After Gastroduodenal Operation] Zhonghua Wei Chang Wai Ke Za Zhi = Chinese Journal of Gastrointestinal Surgery. Sep, 2005 | Pubmed ID: 16224659 Functional and Morphological Changes of the Gut Barrier During the Restitution Process After Hemorrhagic Shock World Journal of Gastroenterology. Sep, 2005 | Pubmed ID: 16222741 Protective Effects of Recombinant Human Growth Hormone on Cirrhotic Rats World Journal of Gastroenterology. Oct, 2004 | Pubmed ID: 15334695 [Study on Morphological Change in Intestinal Mucosa from Injury to Repair After Hemorrhagic Shock] Zhongguo Wei Zhong Bing Ji Jiu Yi Xue = Chinese Critical Care Medicine = Zhongguo Weizhongbing Jijiuyixue. Aug, 2004 | Pubmed ID: 15298805 Expression of Growth Hormone Receptor and Its MRNA in Hepatic Cirrhosis World Journal of Gastroenterology. Apr, 2003 | Pubmed ID: 12679928 [Expression of Growth Hormone Receptor MRNA in Hepatocellular Carcinoma and Matched Para-cancer Cirrhotic Liver Tissue] Ai Zheng = Aizheng = Chinese Journal of Cancer. Feb, 2002 | Pubmed ID: 12479063 [Expression of Growth Hormone Receptor and Its MRNA in Cirrhotic Livers] Zhonghua Yi Xue Za Zhi. Feb, 2002 | Pubmed ID: 11953152 लैप्रोस्कोपिक चीरा हर्निया मरम्मत में एक नई जाल निर्धारण विधि का अनुप्रयोग Ning Ma*1, Dai Tang*2, Fu-xing Tang1, En-min Huang1, Tao Ma1, Wei-sheng Yang1, Chuang-xiong Liu1, Hao-nan Huang1, Shuang Chen1, Tai-cheng Zhou1 1Department of Gastroenterological Surgery and Hernia Center, The Sixth Affiliated Hospital, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangzhou, Sun Yat-sen University, 2Department of Gastrointestinal Surgery, the Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi) JoVE 64916 Medicine Application of Straight-needle, Three-tailed, Knot-free, Peritoneal Sutures in Laparoscopic Transabdominal Preperitoneal Hernia Repair JoVE 63233 Medicine मॉडल फेफड़ों स्क्वैमस कार्सिनोमा प्रगति के लिए बहुआयामी सहसंस्कृति प्रणाली Shuang Chen1, Andreas Giannakou1, Jonathon Golas1, Kenneth G. Geles1 1Oncology R&D group, Pfizer Worldwide Research and Development JoVE 60644 Cancer Research
लैप्रोस्कोपिक चीरा हर्निया मरम्मत में एक नई जाल निर्धारण विधि का अनुप्रयोग Ning Ma*1, Dai Tang*2, Fu-xing Tang1, En-min Huang1, Tao Ma1, Wei-sheng Yang1, Chuang-xiong Liu1, Hao-nan Huang1, Shuang Chen1, Tai-cheng Zhou1 1Department of Gastroenterological Surgery and Hernia Center, The Sixth Affiliated Hospital, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangzhou, Sun Yat-sen University, 2Department of Gastrointestinal Surgery, the Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi) JoVE 64916 Medicine
Application of Straight-needle, Three-tailed, Knot-free, Peritoneal Sutures in Laparoscopic Transabdominal Preperitoneal Hernia Repair JoVE 63233 Medicine
मॉडल फेफड़ों स्क्वैमस कार्सिनोमा प्रगति के लिए बहुआयामी सहसंस्कृति प्रणाली Shuang Chen1, Andreas Giannakou1, Jonathon Golas1, Kenneth G. Geles1 1Oncology R&D group, Pfizer Worldwide Research and Development JoVE 60644 Cancer Research
